-
1
-
-
0347123435
-
Mucins in cancer: Protection and control of the cell surface
-
Hollingsworth, M. A.; Swanson, B. J. Mucins in cancer: protection and control of the cell surface. Nat. Rev. Cancer 2004, 4, 45-60.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 45-60
-
-
Hollingsworth, M.A.1
Swanson, B.J.2
-
2
-
-
42049099903
-
Structure, evolution, and biology of the MUC4 mucin
-
Chaturvedi, P.; Singh, A. P.; Batra, S. K. Structure, evolution, and biology of the MUC4 mucin. FASEB J. 2008, 22, 966-981.
-
(2008)
FASEB J.
, vol.22
, pp. 966-981
-
-
Chaturvedi, P.1
Singh, A.P.2
Batra, S.K.3
-
3
-
-
79955105128
-
MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells
-
Ponnusamy, M. P.; Seshacharyulu, P.; Vaz, A.; Dey, P.; Batra, S. K. MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells. J. Ovarian Res. 2011, 4, 7.
-
(2011)
J. Ovarian Res.
, vol.4
, pp. 7
-
-
Ponnusamy, M.P.1
Seshacharyulu, P.2
Vaz, A.3
Dey, P.4
Batra, S.K.5
-
4
-
-
70349653064
-
Pancreatic cancer cells resistance to gemcitabine: The role of MUC4 mucin
-
Bafna, S.; Kaur, S.; Momi, N.; Batra, S. K. Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin. Br. J. Cancer 2009, 101, 1155-1161.
-
(2009)
Br. J. Cancer
, vol.101
, pp. 1155-1161
-
-
Bafna, S.1
Kaur, S.2
Momi, N.3
Batra, S.K.4
-
5
-
-
77950828177
-
MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies
-
Mimeault, M.; Johansson, S. L.; Senapati, S.; Momi, N.; Chakraborty, S.; Batra, S. K. MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies. Cancer Lett. 2010, 295, 69-84.
-
(2010)
Cancer Lett.
, vol.295
, pp. 69-84
-
-
Mimeault, M.1
Johansson, S.L.2
Senapati, S.3
Momi, N.4
Chakraborty, S.5
Batra, S.K.6
-
6
-
-
42049109699
-
MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1
-
Engelmann, K.; Shen, H.; Finn, O. J. MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1. Cancer Res. 2008, 68, 2419-2426.
-
(2008)
Cancer Res.
, vol.68
, pp. 2419-2426
-
-
Engelmann, K.1
Shen, H.2
Finn, O.J.3
-
7
-
-
84865527612
-
Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelialmesenchymal transition
-
Jing, Y.; Han, Z.; Liu, Y.; Sun, K.; Zhang, S.; Jiang, G.; Li, R.; Gao, L.; Zhao, X.; Wu, D.; Cai, X.; Wu, M.; Wei, L. Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelialmesenchymal transition. PLoS One 2012, 7, e43272.
-
(2012)
PLoS One
, vol.7
-
-
Jing, Y.1
Han, Z.2
Liu, Y.3
Sun, K.4
Zhang, S.5
Jiang, G.6
Li, R.7
Gao, L.8
Zhao, X.9
Wu, D.10
Cai, X.11
Wu, M.12
Wei, L.13
-
9
-
-
78650175637
-
Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells
-
Kikuta, K.; Masamune, A.; Watanabe, T.; Ariga, H.; Itoh, H.; Hamada, S.; Satoh, K.; Egawa, S.; Unno, M.; Shimosegawa, T. Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells. Biochem. Biophys. Res. Commun. 2010, 403, 380-384.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.403
, pp. 380-384
-
-
Kikuta, K.1
Masamune, A.2
Watanabe, T.3
Ariga, H.4
Itoh, H.5
Hamada, S.6
Satoh, K.7
Egawa, S.8
Unno, M.9
Shimosegawa, T.10
-
10
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo, A.; Gupta, P. B.; Sgroi, D. C.; Arenzana-Seisdedos, F.; Delaunay, T.; Naeem, R.; Carey, V. J.; Richardson, A. L.; Weinberg, R. A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005, 121, 335-348.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
11
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle, E.; Sancho, E.; Franci, C.; Dominguez, D.; Monfar, M.; Baulida, J.; Garcia De, H. A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2000, 2, 84-89.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Franci, C.3
Dominguez, D.4
Monfar, M.5
Baulida, J.6
De Garcia, H.A.7
-
12
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano, A.; Perez-Moreno, M. A.; Rodrigo, I.; Locascio, A.; Blanco, M. J.; del Barrio, M. G.; Portillo, F.; Nieto, M. A. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2000, 2, 76-83.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
del Barrio, M.G.6
Portillo, F.7
Nieto, M.A.8
-
13
-
-
0037086277
-
The SLUG zinc-finger protein represses E-cadherin in breast cancer
-
Hajra, K. M.; Chen, D. Y.; Fearon, E. R. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res. 2002, 62, 1613-1618.
-
(2002)
Cancer Res.
, vol.62
, pp. 1613-1618
-
-
Hajra, K.M.1
Chen, D.Y.2
Fearon, E.R.3
-
14
-
-
0034964418
-
The twohanded E box binding zinc finger protein SIP1 downregulates Ecadherin and induces invasion
-
Comijn, J.; Berx, G.; Vermassen, P.; Verschueren, K.; van, G. L.; Bruyneel, E.; Mareel, M.; Huylebroeck, D.; van, R. F. The twohanded E box binding zinc finger protein SIP1 downregulates Ecadherin and induces invasion. Mol. Cell 2001, 7, 1267-1278.
-
(2001)
Mol. Cell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
van, G.L.5
Bruyneel, E.6
Mareel, M.7
Huylebroeck, D.8
van, R.F.9
-
15
-
-
20144388095
-
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
-
Eger, A.; Aigner, K.; Sonderegger, S.; Dampier, B.; Oehler, S.; Schreiber, M.; Berx, G.; Cano, A.; Beug, H.; Foisner, R. DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene. 2005, 24(14), 2375-2385.
-
(2005)
Oncogene.
, vol.24
, Issue.14
, pp. 2375-2385
-
-
Eger, A.1
Aigner, K.2
Sonderegger, S.3
Dampier, B.4
Oehler, S.5
Schreiber, M.6
Berx, G.7
Cano, A.8
Beug, H.9
Foisner, R.10
-
16
-
-
34547620873
-
Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion
-
Wang, X.; Zheng, M.; Liu, G.; Xia, W.; McKeown-Longo, P. J.; Hung, M. C.; Zhao, J. Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Cancer Res. 2007, 67, 7184-7193.
-
(2007)
Cancer Res.
, vol.67
, pp. 7184-7193
-
-
Wang, X.1
Zheng, M.2
Liu, G.3
Xia, W.4
McKeown-Longo, P.J.5
Hung, M.C.6
Zhao, J.7
-
17
-
-
0035920152
-
A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
-
Perez-Moreno, M. A.; Locascio, A.; Rodrigo, I.; Dhondt, G.; Portillo, F.; Nieto, M. A.; Cano, A. A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J. Biol. Chem. 2001, 276, 27424-27431.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27424-27431
-
-
Perez-Moreno, M.A.1
Locascio, A.2
Rodrigo, I.3
Dhondt, G.4
Portillo, F.5
Nieto, M.A.6
Cano, A.7
-
18
-
-
76649138588
-
The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells
-
Fernando, R. I.; Litzinger, M.; Trono, P.; Hamilton, D. H.; Schlom, J.; Palena, C. The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. J. Clin. Invest. 2010, 120, 533-544.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 533-544
-
-
Fernando, R.I.1
Litzinger, M.2
Trono, P.3
Hamilton, D.H.4
Schlom, J.5
Palena, C.6
-
19
-
-
22244432840
-
The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program
-
De, C. B.; Gilbert, B.; Stove, C.; Bruyneel, E.; van, R. F.; Berx, G. The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. Cancer Res. 2005, 65, 6237-6244.
-
(2005)
Cancer Res.
, vol.65
, pp. 6237-6244
-
-
De, C.B.1
Gilbert, B.2
Stove, C.3
Bruyneel, E.4
van, R.F.5
Berx, G.6
-
20
-
-
33750358078
-
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition
-
Moreno-Bueno, G.; Cubillo, E.; Sarrio, D.; Peinado, H.; Rodriguez-Pinilla, S. M.; Villa, S.; Bolos, V.; Jorda, M.; Fabra, A.; Portillo, F.; Palacios, J.; Cano, A. Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res. 2006, 66, 9543-9556.
-
(2006)
Cancer Res.
, vol.66
, pp. 9543-9556
-
-
Moreno-Bueno, G.1
Cubillo, E.2
Sarrio, D.3
Peinado, H.4
Rodriguez-Pinilla, S.M.5
Villa, S.6
Bolos, V.7
Jorda, M.8
Fabra, A.9
Portillo, F.10
Palacios, J.11
Cano, A.12
-
21
-
-
29144485712
-
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
-
Vandewalle, C.; Comijn, J.; De, C. B.; Vermassen, P.; Bruyneel, E.; Andersen, H.; Tulchinsky, E.; van, R. F.; Berx, G. SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic Acids Res. 2005, 33, 6566-6578.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 6566-6578
-
-
Vandewalle, C.1
Comijn, J.2
De, C.B.3
Vermassen, P.4
Bruyneel, E.5
Andersen, H.6
Tulchinsky, E.7
van, R.F.8
Berx, G.9
-
22
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang, J.; Mani, S. A.; Donaher, J. L.; Ramaswamy, S.; Itzykson, R. A.; Come, C.; Savagner, P.; Gitelman, I.; Richardson, A.; Weinberg, R.A. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004, 117, 927-939.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
23
-
-
70349205537
-
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition
-
McCoy, E. L.; Iwanaga, R.; Jedlicka, P.; Abbey, N. S.; Chodosh, L. A.; Heichman, K. A.; Welm, A. L.; Ford, H. L. Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition. J. Clin. Invest 2009, 119, 2663-2677.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 2663-2677
-
-
McCoy, E.L.1
Iwanaga, R.2
Jedlicka, P.3
Abbey, N.S.4
Chodosh, L.A.5
Heichman, K.A.6
Welm, A.L.7
Ford, H.L.8
-
24
-
-
34547141894
-
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
-
Mani, S. A.; Yang, J.; Brooks, M.; Schwaninger, G.; Zhou, A.; Miura, N.; Kutok, J. L.; Hartwell, K.; Richardson, A. L.; Weinberg, R. A. Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc. Natl. Acad. Sci. USA 2007, 104, 10069-10074.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 10069-10074
-
-
Mani, S.A.1
Yang, J.2
Brooks, M.3
Schwaninger, G.4
Zhou, A.5
Miura, N.6
Kutok, J.L.7
Hartwell, K.8
Richardson, A.L.9
Weinberg, R.A.10
-
25
-
-
66849104147
-
The class I bHLH factors E2-2A and E2-2B regulate EMT
-
Sobrado, V. R.; Moreno-Bueno, G.; Cubillo, E.; Holt, L. J.; Nieto, M. A.; Portillo, F.; Cano, A. The class I bHLH factors E2-2A and E2-2B regulate EMT. J. Cell Sci. 2009, 122, 1014-1024.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1014-1024
-
-
Sobrado, V.R.1
Moreno-Bueno, G.2
Cubillo, E.3
Holt, L.J.4
Nieto, M.A.5
Portillo, F.6
Cano, A.7
-
26
-
-
84870816403
-
Metastatic colonization requires the repression of the epithelialmesenchymal transition inducer Prrx1
-
Ocana, O. H.; Corcoles, R.; Fabra, A.; Moreno-Bueno, G.; Acloque, H.; Vega, S.; Barrallo-Gimeno, A.; Cano, A.; Nieto, M.A. Metastatic colonization requires the repression of the epithelialmesenchymal transition inducer Prrx1. Cancer Cell 2012, 22, 709-724.
-
(2012)
Cancer Cell
, vol.22
, pp. 709-724
-
-
Ocana, O.H.1
Corcoles, R.2
Fabra, A.3
Moreno-Bueno, G.4
Acloque, H.5
Vega, S.6
Barrallo-Gimeno, A.7
Cano, A.8
Nieto, M.A.9
-
27
-
-
0031215023
-
The epithelial cell default-phenotype hypothesis and its implications for cancer
-
Frisch, S. M. The epithelial cell default-phenotype hypothesis and its implications for cancer. Bioessays 1997, 19, 705-709.
-
(1997)
Bioessays
, vol.19
, pp. 705-709
-
-
Frisch, S.M.1
-
28
-
-
47249091921
-
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
-
Korpal, M.; Lee, E. S.; Hu, G.; Kang, Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J. Biol. Chem. 2008, 283, 14910-14914.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
29
-
-
84862703901
-
Smad3 regulates E-cadherin via miRNA-200 pathway
-
Ahn, S. M.; Cha, J. Y.; Kim, J.; Kim, D.; Trang, H. T.; Kim, Y. M.; Cho, Y. H.; Park, D.; Hong, S. Smad3 regulates E-cadherin via miRNA-200 pathway. Oncogene 2012, 31, 3051-3059.
-
(2012)
Oncogene
, vol.31
, pp. 3051-3059
-
-
Ahn, S.M.1
Cha, J.Y.2
Kim, J.3
Kim, D.4
Trang, H.T.5
Kim, Y.M.6
Cho, Y.H.7
Park, D.8
Hong, S.9
-
30
-
-
84856006660
-
miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-tomesenchymal transition
-
Zhang, Z.; Liu, S.; Shi, R.; Zhao, G. miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-tomesenchymal transition. Cancer Genet. 2011, 204, 486-491.
-
(2011)
Cancer Genet.
, vol.204
, pp. 486-491
-
-
Zhang, Z.1
Liu, S.2
Shi, R.3
Zhao, G.4
-
31
-
-
0034604110
-
Role of transforming growth factor beta in human disease
-
Blobe, G. C.; Schiemann, W. P.; Lodish, H. F. Role of transforming growth factor beta in human disease. N. Engl. J. Med. 2000, 342, 1350-1358.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
32
-
-
71049163832
-
Promoter-wide analysis of Smad4 binding sites in human epithelial cells
-
Koinuma, D.; Tsutsumi, S.; Kamimura, N.; Imamura, T.; Aburatani, H.; Miyazono, K. Promoter-wide analysis of Smad4 binding sites in human epithelial cells. Cancer Sci. 2009, 100, 2133-2142.
-
(2009)
Cancer Sci.
, vol.100
, pp. 2133-2142
-
-
Koinuma, D.1
Tsutsumi, S.2
Kamimura, N.3
Imamura, T.4
Aburatani, H.5
Miyazono, K.6
-
33
-
-
79952706985
-
Transforming growth factor-beta and the hallmarks of cancer
-
Tian, M.; Neil, J. R.; Schiemann, W. P. Transforming growth factor-beta and the hallmarks of cancer. Cell Signal. 2011, 23, 951-962.
-
(2011)
Cell Signal.
, vol.23
, pp. 951-962
-
-
Tian, M.1
Neil, J.R.2
Schiemann, W.P.3
-
34
-
-
0026009094
-
TWIST and SNAIL as positive and negative regulators during Drosophila mesoderm development
-
Leptin, M. TWIST and SNAIL as positive and negative regulators during Drosophila mesoderm development. Genes Dev. 1991, 5, 1568-1576.
-
(1991)
Genes Dev.
, vol.5
, pp. 1568-1576
-
-
Leptin, M.1
-
35
-
-
84857119664
-
Deconstructing the mechanisms and consequences of TGF-beta-induced EMT during cancer progression
-
Wendt, M. K.; Tian, M.; Schiemann, W. P. Deconstructing the mechanisms and consequences of TGF-beta-induced EMT during cancer progression. Cell Tissue Res. 2012, 347, 85-101.
-
(2012)
Cell Tissue Res.
, vol.347
, pp. 85-101
-
-
Wendt, M.K.1
Tian, M.2
Schiemann, W.P.3
-
36
-
-
84860431089
-
A novel human Smad4 mutation is involved in papillary thyroid carcinoma progression
-
D'Inzeo, S.; Nicolussi, A.; Donini, C. F.; Zani, M.; Mancini, P.; Nardi, F.; Coppa, A. A novel human Smad4 mutation is involved in papillary thyroid carcinoma progression. Endocr. Relat. Cancer 2012, 19, 39-55.
-
(2012)
Endocr. Relat. Cancer
, vol.19
, pp. 39-55
-
-
D'Inzeo, S.1
Nicolussi, A.2
Donini, C.F.3
Zani, M.4
Mancini, P.5
Nardi, F.6
Coppa, A.7
-
37
-
-
84855999650
-
E/N-cadherin switch mediates cancer progression via TGF-beta-induced epithelialto-mesenchymal transition in extrahepatic cholangiocarcinoma
-
Araki, K.; Shimura, T.; Suzuki, H.; Tsutsumi, S.; Wada, W.; Yajima, T.; Kobayahi, T.; Kubo, N.; Kuwano, H. E/N-cadherin switch mediates cancer progression via TGF-beta-induced epithelialto-mesenchymal transition in extrahepatic cholangiocarcinoma. Br. J. Cancer 2011, 105, 1885-1893.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 1885-1893
-
-
Araki, K.1
Shimura, T.2
Suzuki, H.3
Tsutsumi, S.4
Wada, W.5
Yajima, T.6
Kobayahi, T.7
Kubo, N.8
Kuwano, H.9
-
38
-
-
33751514601
-
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells
-
Yook, J. I.; Li, X. Y.; Ota, I.; Hu, C.; Kim, H. S.; Kim, N. H.; Cha, S. Y.; Ryu, J. K.; Choi, Y. J.; Kim, J.; Fearon, E. R.; Weiss, S. J. A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nat. Cell Biol. 2006, 8, 1398-1406.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1398-1406
-
-
Yook, J.I.1
Li, X.Y.2
Ota, I.3
Hu, C.4
Kim, H.S.5
Kim, N.H.6
Cha, S.Y.7
Ryu, J.K.8
Choi, Y.J.9
Kim, J.10
Fearon, E.R.11
Weiss, S.J.12
-
39
-
-
79551681371
-
SFRP1 reduction results in an increased sensitivity to TGF-beta signaling
-
Gauger, K. J.; Chenausky, K. L.; Murray, M. E.; Schneider, S. S. SFRP1 reduction results in an increased sensitivity to TGF-beta signaling. BMC Cancer 2011, 11, 59-11.
-
(2011)
BMC Cancer
, vol.11
, pp. 11-59
-
-
Gauger, K.J.1
Chenausky, K.L.2
Murray, M.E.3
Schneider, S.S.4
-
40
-
-
77956521605
-
The role of serum response factor in hepatocellular carcinoma: Implications for disease progression
-
Kwon, C. Y.; Kim, K. R.; Choi, H. N.; Chung, M. J.; Noh, S. J.; Kim, D. G.; Kang, M. J.; Lee, D. G.; Moon, W. S. The role of serum response factor in hepatocellular carcinoma: implications for disease progression. Int. J. Oncol. 2010, 37, 837-844.
-
(2010)
Int. J. Oncol.
, vol.37
, pp. 837-844
-
-
Kwon, C.Y.1
Kim, K.R.2
Choi, H.N.3
Chung, M.J.4
Noh, S.J.5
Kim, D.G.6
Kang, M.J.7
Lee, D.G.8
Moon, W.S.9
-
41
-
-
34250744600
-
Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions
-
Doble, B. W.; Woodgett, J. R. Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions. Cells Tissues Organs 2007, 185, 73-84.
-
(2007)
Cells Tissues Organs
, vol.185
, pp. 73-84
-
-
Doble, B.W.1
Woodgett, J.R.2
-
42
-
-
77950683362
-
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling
-
Heuberger, J.; Birchmeier, W. Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb. Perspect. Biol. 2010, 2, a002915.
-
(2010)
Cold Spring Harb. Perspect. Biol.
, vol.2
-
-
Heuberger, J.1
Birchmeier, W.2
-
43
-
-
34250867977
-
Notch signaling in development and cancer
-
Bolos, V.; Grego-Bessa, J.; de la Pompa, J. L. Notch signaling in development and cancer. Endocr. Rev. 2007, 28, 339-363.
-
(2007)
Endocr. Rev.
, vol.28
, pp. 339-363
-
-
Bolos, V.1
Grego-Bessa, J.2
de la Pompa, J.L.3
-
44
-
-
84863393099
-
A monoclonal antibody against human Notch1 ligand-binding domain depletes subpopulation of putative breast cancer stem-like cells
-
Sharma, A.; Paranjape, A. N.; Rangarajan, A.; Dighe, R. R. A monoclonal antibody against human Notch1 ligand-binding domain depletes subpopulation of putative breast cancer stem-like cells. Mol. Cancer Ther. 2012, 11, 77-86.
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 77-86
-
-
Sharma, A.1
Paranjape, A.N.2
Rangarajan, A.3
Dighe, R.R.4
-
45
-
-
78649466892
-
Targeting Notch signaling pathway to overcome drug resistance for cancer therapy
-
Wang, Z.; Li, Y.; Ahmad, A.; Azmi, A. S.; Banerjee, S.; Kong, D.; Sarkar, F. H. Targeting Notch signaling pathway to overcome drug resistance for cancer therapy. Biochim. Biophys. Acta 2010, 1806, 258-267.
-
(2010)
Biochim. Biophys. Acta
, vol.1806
, pp. 258-267
-
-
Wang, Z.1
Li, Y.2
Ahmad, A.3
Azmi, A.S.4
Banerjee, S.5
Kong, D.6
Sarkar, F.H.7
-
46
-
-
9144246932
-
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
-
Timmerman, L. A.; Grego-Bessa, J.; Raya, A.; Bertran, E.; Perez-Pomares, J. M.; Diez, J.; Aranda, S.; Palomo, S.; McCormick, F.; Izpisua-Belmonte, J. C.; de la Pompa, J. L. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 2004, 18, 99-115.
-
(2004)
Genes Dev.
, vol.18
, pp. 99-115
-
-
Timmerman, L.A.1
Grego-Bessa, J.2
Raya, A.3
Bertran, E.4
Perez-Pomares, J.M.5
Diez, J.6
Aranda, S.7
Palomo, S.8
McCormick, F.9
Izpisua-Belmonte, J.C.10
de la Pompa, J.L.11
-
47
-
-
79957487931
-
Notch-1 induces epithelialmesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
-
Bao, B.; Wang, Z.; Ali, S.; Kong, D.; Li, Y.; Ahmad, A.; Banerjee, S.; Azmi, A. S.; Miele, L.; Sarkar, F. H. Notch-1 induces epithelialmesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett. 2011, 307, 26-36.
-
(2011)
Cancer Lett.
, vol.307
, pp. 26-36
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
Kong, D.4
Li, Y.5
Ahmad, A.6
Banerjee, S.7
Azmi, A.S.8
Miele, L.9
Sarkar, F.H.10
-
48
-
-
79951813950
-
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
-
Brabletz, S.; Bajdak, K.; Meidhof, S.; Burk, U.; Niedermann, G.; Firat, E.; Wellner, U.; Dimmler, A.; Faller, G.; Schubert, J.; Brabletz, T. The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J. 2011, 30, 770-782.
-
(2011)
EMBO J.
, vol.30
, pp. 770-782
-
-
Brabletz, S.1
Bajdak, K.2
Meidhof, S.3
Burk, U.4
Niedermann, G.5
Firat, E.6
Wellner, U.7
Dimmler, A.8
Faller, G.9
Schubert, J.10
Brabletz, T.11
-
49
-
-
79953329774
-
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
-
Yang, Y.; Ahn, Y. H.; Gibbons, D. L.; Zang, Y.; Lin, W.; Thilaganathan, N.; Alvarez, C. A.; Moreira, D. C.; Creighton, C. J.; Gregory, P. A.; Goodall, G. J.; Kurie, J. M. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J. Clin. Invest. 2011, 121, 1373-1385.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1373-1385
-
-
Yang, Y.1
Ahn, Y.H.2
Gibbons, D.L.3
Zang, Y.4
Lin, W.5
Thilaganathan, N.6
Alvarez, C.A.7
Moreira, D.C.8
Creighton, C.J.9
Gregory, P.A.10
Goodall, G.J.11
Kurie, J.M.12
-
50
-
-
0037108828
-
Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation
-
Louro, I. D.; Bailey, E. C.; Li, X.; South, L. S.; McKie-Bell, P. R.; Yoder, B. K.; Huang, C. C.; Johnson, M. R.; Hill, A. E.; Johnson, R. L.; Ruppert, J. M. Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation. Cancer Res. 2002, 62, 5867-5873.
-
(2002)
Cancer Res.
, vol.62
, pp. 5867-5873
-
-
Louro, I.D.1
Bailey, E.C.2
Li, X.3
South, L.S.4
McKie-Bell, P.R.5
Yoder, B.K.6
Huang, C.C.7
Johnson, M.R.8
Hill, A.E.9
Johnson, R.L.10
Ruppert, J.M.11
-
51
-
-
79251547708
-
Upregulation of sonic hedgehog contributes to TGF-beta1-induced epithelial to mesenchymal transition in NSCLC cells
-
Maitah, M. Y.; Ali, S.; Ahmad, A.; Gadgeel, S.; Sarkar, F. H. Upregulation of sonic hedgehog contributes to TGF-beta1-induced epithelial to mesenchymal transition in NSCLC cells. PLoS One 2011, 6, e16068.
-
(2011)
PLoS One
, vol.6
-
-
Maitah, M.Y.1
Ali, S.2
Ahmad, A.3
Gadgeel, S.4
Sarkar, F.H.5
-
52
-
-
81155126047
-
Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer
-
Yoo, Y. A.; Kang, M. H.; Lee, H. J.; Kim, B. H.; Park, J. K.; Kim, H. K.; Kim, J. S.; Oh, S. C. Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer. Cancer Res. 2011, 71, 7061-7070.
-
(2011)
Cancer Res.
, vol.71
, pp. 7061-7070
-
-
Yoo, Y.A.1
Kang, M.H.2
Lee, H.J.3
Kim, B.H.4
Park, J.K.5
Kim, H.K.6
Kim, J.S.7
Oh, S.C.8
-
53
-
-
84855391207
-
GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells
-
Joost, S.; Almada, L. L.; Rohnalter, V.; Holz, P. S.; Vrabel, A. M.; Fernandez-Barrena, M. G.; McWilliams, R. R.; Krause, M.; Fernandez-Zapico, M. E.; Lauth, M. GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells. Cancer Res. 2012, 72, 88-99.
-
(2012)
Cancer Res.
, vol.72
, pp. 88-99
-
-
Joost, S.1
Almada, L.L.2
Rohnalter, V.3
Holz, P.S.4
Vrabel, A.M.5
Fernandez-Barrena, M.G.6
McWilliams, R.R.7
Krause, M.8
Fernandez-Zapico, M.E.9
Lauth, M.10
-
54
-
-
56449088532
-
MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells
-
Bafna, S.; Singh, A. P.; Moniaux, N.; Eudy, J. D.; Meza, J. L.; Batra, S. K. MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells. Cancer Res. 2008, 68, 9231-9238.
-
(2008)
Cancer Res.
, vol.68
, pp. 9231-9238
-
-
Bafna, S.1
Singh, A.P.2
Moniaux, N.3
Eudy, J.D.4
Meza, J.L.5
Batra, S.K.6
-
55
-
-
42049105135
-
MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells
-
Chaturvedi, P.; Singh, A. P.; Chakraborty, S.; Chauhan, S. C.; Bafna, S.; Meza, J. L.; Singh, P. K.; Hollingsworth, M. A.; Mehta, P. P.; Batra, S. K. MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells. Cancer Res. 2008, 68, 2065-2070.
-
(2008)
Cancer Res.
, vol.68
, pp. 2065-2070
-
-
Chaturvedi, P.1
Singh, A.P.2
Chakraborty, S.3
Chauhan, S.C.4
Bafna, S.5
Meza, J.L.6
Singh, P.K.7
Hollingsworth, M.A.8
Mehta, P.P.9
Batra, S.K.10
-
56
-
-
84873682464
-
MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells
-
Mukhopadhyay, P.; Lakshmanan, I.; Ponnusamy, M. P.; Chakraborty, S.; Jain, M.; Pai, P.; Smith, L. M.; Lele, S. M.; Batra, S. K. MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells. PLoS One 2013, 8, e54455.
-
(2013)
PLoS One
, vol.8
-
-
Mukhopadhyay, P.1
Lakshmanan, I.2
Ponnusamy, M.P.3
Chakraborty, S.4
Jain, M.5
Pai, P.6
Smith, L.M.7
Lele, S.M.8
Batra, S.K.9
-
57
-
-
48349129798
-
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells
-
Ponnusamy, M. P.; Singh, A. P.; Jain, M.; Chakraborty, S.; Moniaux, N.; Batra, S. K. MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells. Br. J. Cancer. 2008, 99, 520-526.
-
(2008)
Br. J. Cancer.
, vol.99
, pp. 520-526
-
-
Ponnusamy, M.P.1
Singh, A.P.2
Jain, M.3
Chakraborty, S.4
Moniaux, N.5
Batra, S.K.6
-
58
-
-
77958451128
-
MUC4 mucin-induced epithelial to mesenchymal transition: A novel mechanism for metastasis of human ovarian cancer cells
-
Ponnusamy, M. P.; Lakshmanan, I.; Jain, M.; Das, S.; Chakraborty, S.; Dey, P.; Batra, S.K. MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells. Oncogene 2010, 29, 5741-5754.
-
(2010)
Oncogene
, vol.29
, pp. 5741-5754
-
-
Ponnusamy, M.P.1
Lakshmanan, I.2
Jain, M.3
Das, S.4
Chakraborty, S.5
Dey, P.6
Batra, S.K.7
-
59
-
-
84867311798
-
MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1
-
Rachagani, S.; Macha, M. A.; Ponnusamy, M. P.; Haridas, D.; Kaur, S.; Jain, M.; Batra, S. K. MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1. Carcinogenesis 2012, 33, 1953-1964.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1953-1964
-
-
Rachagani, S.1
Macha, M.A.2
Ponnusamy, M.P.3
Haridas, D.4
Kaur, S.5
Jain, M.6
Batra, S.K.7
-
60
-
-
84890310936
-
The role of tumour-associated MUC1 in epithelial ovarian cancer metastasis and progression
-
[Epub ahead of print]
-
Deng, J.; Wang, L.; Chen, H.; Li, L.; Ma, Y.; Ni, J.; Li, Y. The role of tumour-associated MUC1 in epithelial ovarian cancer metastasis and progression. Cancer Metastasis Rev. 2013. [Epub ahead of print]
-
(2013)
Cancer Metastasis Rev.
-
-
Deng, J.1
Wang, L.2
Chen, H.3
Li, L.4
Ma, Y.5
Ni, J.6
Li, Y.7
-
61
-
-
77953178125
-
Mucin 1 oncoprotein expression is suppressed by the Mir-125b Oncomir
-
Rajabi, H.; Jin, C.; Ahmad, R.; McClary, C.; Joshi, M. D.; Kufe, D. Mucin 1 oncoprotein expression is suppressed by the Mir-125b Oncomir. Genes Cancer. 2010, 1, 62-68.
-
(2010)
Genes Cancer.
, vol.1
, pp. 62-68
-
-
Rajabi, H.1
Jin, C.2
Ahmad, R.3
McClary, C.4
Joshi, M.D.5
Kufe, D.6
-
62
-
-
84897998624
-
MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition
-
[Epub ahead of print]
-
Rajabi, H.; Alam, M.; Takahashi, H.; Kharbanda, A.; Guha, M.; Ahmad, R.; Kufe, D. MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition. Oncogene. 2013, 10. [Epub ahead of print]
-
(2013)
Oncogene.
, pp. 10
-
-
Rajabi, H.1
Alam, M.2
Takahashi, H.3
Kharbanda, A.4
Guha, M.5
Ahmad, R.6
Kufe, D.7
-
63
-
-
79953061206
-
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
-
Roy, L. D.; Sahraei, M.; Subramani, D. B.; Besmer, D.; Nath, S.; Tinder, T. L.; Bajaj, E.; Shanmugam, K.; Lee, Y. Y.; Hwang, S. I.; Gendler, S. J.; Mukherjee, P. MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. Oncogene 2011, 30, 1449-1459.
-
(2011)
Oncogene
, vol.30
, pp. 1449-1459
-
-
Roy, L.D.1
Sahraei, M.2
Subramani, D.B.3
Besmer, D.4
Nath, S.5
Tinder, T.L.6
Bajaj, E.7
Shanmugam, K.8
Lee, Y.Y.9
Hwang, S.I.10
Gendler, S.J.11
Mukherjee, P.12
-
64
-
-
64049093492
-
ERK and PI3K regulate different aspects of the epithelial to mesenchymal transition of mammary tumor cells induced by truncated MUC1
-
Horn, G.; Gaziel, A.; Wreschner, D. H.; Smorodinsky, N. I.; Ehrlich, M. ERK and PI3K regulate different aspects of the epithelial to mesenchymal transition of mammary tumor cells induced by truncated MUC1. Exp. Cell Res. 2009, 315, 1490-1504.
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 1490-1504
-
-
Horn, G.1
Gaziel, A.2
Wreschner, D.H.3
Smorodinsky, N.I.4
Ehrlich, M.5
-
65
-
-
84867047477
-
MUC1-C oncoprotein confers androgenindependent growth of human prostate cancer cells
-
Rajabi, H.; Ahmad, R.; Jin, C.; Joshi, M. D.; Guha, M.; Alam, M.; Kharbanda, S.; Kufe, D. MUC1-C oncoprotein confers androgenindependent growth of human prostate cancer cells. Prostate 2012, 72, 1659-1668.
-
(2012)
Prostate
, vol.72
, pp. 1659-1668
-
-
Rajabi, H.1
Ahmad, R.2
Jin, C.3
Joshi, M.D.4
Guha, M.5
Alam, M.6
Kharbanda, S.7
Kufe, D.8
-
66
-
-
84875392649
-
Pathobiological implications of MUC4 in non-smallcell lung cancer
-
Majhi, P. D.; Lakshmanan, I.; Ponnusamy, M. P.; Jain, M.; Das, S.; Kaur, S.; Shimizu, S. T.; West, W. W.; Johansson, S. L.; Smith, L. M.; Yu, F.; Rolle, C. E.; Sharma, P.; Carey, G. B.; Batra, S. K.; Ganti, A. K. Pathobiological implications of MUC4 in non-smallcell lung cancer. J. Thorac. Oncol. 2013, 8, 398-407.
-
(2013)
J. Thorac. Oncol.
, vol.8
, pp. 398-407
-
-
Majhi, P.D.1
Lakshmanan, I.2
Ponnusamy, M.P.3
Jain, M.4
Das, S.5
Kaur, S.6
Shimizu, S.T.7
West, W.W.8
Johansson, S.L.9
Smith, L.M.10
Yu, F.11
Rolle, C.E.12
Sharma, P.13
Carey, G.B.14
Batra, S.K.15
Ganti, A.K.16
-
67
-
-
79952704437
-
Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells
-
Comamala, M.; Pinard, M.; Theriault, C.; Matte, I.; Albert, A.; Boivin, M.; Beaudin, J.; Piche, A.; Rancourt, C. Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells. Br. J. Cancer 2011, 104, 989-999.
-
(2011)
Br. J. Cancer
, vol.104
, pp. 989-999
-
-
Comamala, M.1
Pinard, M.2
Theriault, C.3
Matte, I.4
Albert, A.5
Boivin, M.6
Beaudin, J.7
Piche, A.8
Rancourt, C.9
-
68
-
-
79957525887
-
MUC16 (CA125) regulates epithelial ovarian cancer cell growth, tumorigenesis and metastasis
-
Theriault, C.; Pinard, M.; Comamala, M.; Migneault, M.; Beaudin, J.; Matte, I.; Boivin, M.; Piche, A.; Rancourt, C. MUC16 (CA125) regulates epithelial ovarian cancer cell growth, tumorigenesis and metastasis. Gynecol. Oncol. 2011, 121, 434-443.
-
(2011)
Gynecol. Oncol.
, vol.121
, pp. 434-443
-
-
Theriault, C.1
Pinard, M.2
Comamala, M.3
Migneault, M.4
Beaudin, J.5
Matte, I.6
Boivin, M.7
Piche, A.8
Rancourt, C.9
-
69
-
-
79957519171
-
More than a biomarker: CA125 may contribute to ovarian cancer pathogenesis
-
Bast, R. C. Jr.; Spriggs, D. R. More than a biomarker: CA125 may contribute to ovarian cancer pathogenesis. Gynecol. Oncol. 2011, 121, 429-430.
-
(2011)
Gynecol. Oncol.
, vol.121
, pp. 429-430
-
-
Bast Jr., R.C.1
Spriggs, D.R.2
-
70
-
-
33750998782
-
Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors
-
Gubbels, J. A.; Belisle, J.; Onda, M.; Rancourt, C.; Migneault, M.; Ho, M.; Bera, T. K.; Connor, J.; Sathyanarayana, B. K.; Lee, B.; Pastan, I.; Patankar, M. S. Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors. Mol. Cancer 2006, 5, 50.
-
(2006)
Mol. Cancer
, vol.5
, pp. 50
-
-
Gubbels, J.A.1
Belisle, J.2
Onda, M.3
Rancourt, C.4
Migneault, M.5
Ho, M.6
Bera, T.K.7
Connor, J.8
Sathyanarayana, B.K.9
Lee, B.10
Pastan, I.11
Patankar, M.S.12
-
71
-
-
0032473494
-
Gastric M1 mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene
-
Bara, J.; Chastre, E.; Mahiou, J.; Singh, R. L.; Forgue-Lafitte, M. E.; Hollande, E.; Godeau, F. Gastric M1 mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene. Int. J. Cancer 1998, 75, 767-773.
-
(1998)
Int. J. Cancer
, vol.75
, pp. 767-773
-
-
Bara, J.1
Chastre, E.2
Mahiou, J.3
Singh, R.L.4
Forgue-Lafitte, M.E.5
Hollande, E.6
Godeau, F.7
-
72
-
-
0025953376
-
Increased growth adaptability to 5-fluorouracil and methotrexate of HT-29 sub-populations selected for their commitment to differentiation
-
Lesuffleur, T.; Kornowski, A.; Augeron, C.; Dussaulx, E.; Barbat, A.; Laboisse, C.; Zweibaum, A. Increased growth adaptability to 5-fluorouracil and methotrexate of HT-29 sub-populations selected for their commitment to differentiation. Int. J. Cancer 1991, 49, 731-737.
-
(1991)
Int. J. Cancer
, vol.49
, pp. 731-737
-
-
Lesuffleur, T.1
Kornowski, A.2
Augeron, C.3
Dussaulx, E.4
Barbat, A.5
Laboisse, C.6
Zweibaum, A.7
-
73
-
-
0034782288
-
Differential expression of the chromosome 11 mucin genes in colorectal cancer
-
Sylvester, P. A.; Myerscough, N.; Warren, B. F.; Carlstedt, I.; Corfield, A. P.; Durdey, P.; Thomas, M. G. Differential expression of the chromosome 11 mucin genes in colorectal cancer. J. Pathol. 2001, 195, 327-335.
-
(2001)
J. Pathol.
, vol.195
, pp. 327-335
-
-
Sylvester, P.A.1
Myerscough, N.2
Warren, B.F.3
Carlstedt, I.4
Corfield, A.P.5
Durdey, P.6
Thomas, M.G.7
-
74
-
-
79951512092
-
GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin
-
Inaguma, S.; Kasai, K.; Ikeda, H. GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin. Oncogene 2011, 30, 714-723.
-
(2011)
Oncogene
, vol.30
, pp. 714-723
-
-
Inaguma, S.1
Kasai, K.2
Ikeda, H.3
-
75
-
-
77952452039
-
RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells
-
Yamazoe, S.; Tanaka, H.; Sawada, T.; Amano, R.; Yamada, N.; Ohira, M.; Hirakawa, K. RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells. J. Exp. Clin. Cancer Res. 2010, 23, 29:53.
-
(2010)
J. Exp. Clin. Cancer Res.
, vol.23
, Issue.29
, pp. 53
-
-
Yamazoe, S.1
Tanaka, H.2
Sawada, T.3
Amano, R.4
Yamada, N.5
Ohira, M.6
Hirakawa, K.7
-
76
-
-
0345269741
-
Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells
-
Truant, S.; Bruyneel, E.; Gouyer, V.; De, W. O.; Pruvot, F. R.; Mareel, M.; Huet, G. Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells. Int. J. Cancer 2003, 104, 683-694.
-
(2003)
Int. J. Cancer
, vol.104
, pp. 683-694
-
-
Truant, S.1
Bruyneel, E.2
Gouyer, V.3
De, W.O.4
Pruvot, F.R.5
Mareel, M.6
Huet, G.7
-
77
-
-
84866995203
-
MUC5B leads to aggressive behavior of breast cancer MCF7 cells
-
Valque, H.; Gouyer, V.; Gottrand, F.; Desseyn, J. L. MUC5B leads to aggressive behavior of breast cancer MCF7 cells. PLoS One 2012, 7, e46699.
-
(2012)
PLoS One
, vol.7
-
-
Valque, H.1
Gouyer, V.2
Gottrand, F.3
Desseyn, J.L.4
-
78
-
-
80052627385
-
MUC6 mucin expression inhibits tumor cell invasion
-
Leir, S. H.; Harris, A. MUC6 mucin expression inhibits tumor cell invasion. Exp. Cell Res. 2011, 317, 2408-2419.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 2408-2419
-
-
Leir, S.H.1
Harris, A.2
-
79
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
-
Singh, A.; Settleman, J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010, 29, 4741-4751.
-
(2010)
Oncogene
, vol.29
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
80
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S. A.; Guo, W.; Liao, M. J.; Eaton, E. N.; Ayyanan, A.; Zhou, A. Y.; Brooks, M.; Reinhard, F.; Zhang, C. C.; Shipitsin, M.; Campbell, L. L.; Polyak, K.; Brisken, C.; Yang, J.; Weinberg, R. A. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133, 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
81
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner, U.; Schubert, J.; Burk, U. C.; Schmalhofer, O.; Zhu, F.; Sonntag, A.; Waldvogel, B.; Vannier, C.; Darling, D.; zur, H. A.; Brunton, V. G.; Morton, J.; Sansom, O.; Schuler, J.; Stemmler, M. P.; Herzberger, C.; Hopt, U.; Keck, T.; Brabletz, S.; Brabletz, T. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat. Cell Biol. 2009, 11, 1487-1495.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
Waldvogel, B.7
Vannier, C.8
Darling, D.9
Zur, H.A.10
Brunton, V.G.11
Morton, J.12
Sansom, O.13
Schuler, J.14
Stemmler, M.P.15
Herzberger, C.16
Hopt, U.17
Keck, T.18
Brabletz, S.19
Brabletz, T.20
more..
-
82
-
-
84879375174
-
TGF-beta1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133(+) A549 cell fraction
-
Tirino, V.; Camerlingo, R.; Bifulco, K.; Irollo, E.; Montella, R.; Paino, F.; Sessa, G.; Carriero, M. V.; Normanno, N.; Rocco, G.; Pirozzi, G. TGF-beta1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133(+) A549 cell fraction. Cell Death Dis. 2013, 4, e620.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Tirino, V.1
Camerlingo, R.2
Bifulco, K.3
Irollo, E.4
Montella, R.5
Paino, F.6
Sessa, G.7
Carriero, M.V.8
Normanno, N.9
Rocco, G.10
Pirozzi, G.11
-
83
-
-
84883354717
-
CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis
-
Gassenmaier, M.; Chen, D.; Buchner, A.; Henkel, L.; Schiemann, M.; Mack, B.; Schendel, D. J.; Zimmermann, W.; Pohla, H. CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis. Stem Cells 2013, 31(8), 1467-1476.
-
(2013)
Stem Cells
, vol.31
, Issue.8
, pp. 1467-1476
-
-
Gassenmaier, M.1
Chen, D.2
Buchner, A.3
Henkel, L.4
Schiemann, M.5
Mack, B.6
Schendel, D.J.7
Zimmermann, W.8
Pohla, H.9
-
84
-
-
0029121284
-
Bone resorption induced by a metastatic human melanoma cell line
-
Hiraga, T.; Nakajima, T.; Ozawa, H. Bone resorption induced by a metastatic human melanoma cell line. Bone 1995, 16, 349-356.
-
(1995)
Bone
, vol.16
, pp. 349-356
-
-
Hiraga, T.1
Nakajima, T.2
Ozawa, H.3
-
85
-
-
58149395521
-
Imatinib mesylate suppresses bone metastases of breast cancer by inhibiting osteoclasts through the blockade of c-Fms signals
-
Hiraga, T.; Nakamura, H. Imatinib mesylate suppresses bone metastases of breast cancer by inhibiting osteoclasts through the blockade of c-Fms signals. Int. J. Cancer 2009, 124, 215-222.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 215-222
-
-
Hiraga, T.1
Nakamura, H.2
-
86
-
-
0029813935
-
An experimental model of bone metastasis by human lung cancer cells: The role of parathyroid hormone-related protein in bone metastasis
-
Iguchi, H.; Tanaka, S.; Ozawa, Y.; Kashiwakuma, T.; Kimura, T.; Hiraga, T.; Ozawa, H.; Kono, A. An experimental model of bone metastasis by human lung cancer cells: the role of parathyroid hormone-related protein in bone metastasis. Cancer Res. 1996, 56, 4040-4043.
-
(1996)
Cancer Res.
, vol.56
, pp. 4040-4043
-
-
Iguchi, H.1
Tanaka, S.2
Ozawa, Y.3
Kashiwakuma, T.4
Kimura, T.5
Hiraga, T.6
Ozawa, H.7
Kono, A.8
-
87
-
-
84875204442
-
Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer
-
Giudice, F. S.; Pinto, D. S. Jr.; Nor, J. E.; Squarize, C. H.; Castilho, R. M. Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer. PLoS One 2013, 8, e58672.
-
(2013)
PLoS One
, vol.8
-
-
Giudice, F.S.1
Pinto Jr., D.S.2
Nor, J.E.3
Squarize, C.H.4
Castilho, R.M.5
-
88
-
-
79957532451
-
Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness
-
Giannoni, E.; Bianchini, F.; Calorini, L.; Chiarugi, P. Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness. Antioxid. Redox Signal. 2011, 14, 2361-2371.
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 2361-2371
-
-
Giannoni, E.1
Bianchini, F.2
Calorini, L.3
Chiarugi, P.4
-
89
-
-
69249221254
-
Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells
-
Sullivan, N. J.; Sasser, A. K.; Axel, A. E.; Vesuna, F.; Raman, V.; Ramirez, N.; Oberyszyn, T. M.; Hall, B. M. Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells. Oncogene 2009, 28, 2940-2947.
-
(2009)
Oncogene
, vol.28
, pp. 2940-2947
-
-
Sullivan, N.J.1
Sasser, A.K.2
Axel, A.E.3
Vesuna, F.4
Raman, V.5
Ramirez, N.6
Oberyszyn, T.M.7
Hall, B.M.8
-
90
-
-
24644487312
-
TGF-beta and epithelial-to-mesenchymal transitions
-
Zavadil, J.; Bottinger, E. P. TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 2005, 24, 5764-5774.
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Bottinger, E.P.2
-
91
-
-
0037572319
-
Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids
-
Bates, R. C.; Mercurio, A. M. Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids. Mol. Biol. Cell. 2003, 14, 1790-1800.
-
(2003)
Mol. Biol. Cell.
, vol.14
, pp. 1790-1800
-
-
Bates, R.C.1
Mercurio, A.M.2
-
92
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
Sahlgren, C.; Gustafsson, M. V.; Jin, S.; Poellinger, L.; Lendahl, U. Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc. Natl. Acad. Sci. USA 2008, 105, 6392-6397.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
93
-
-
21844432918
-
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
-
Radisky, D. C.; Levy, D. D.; Littlepage, L. E.; Liu, H.; Nelson, C. M.; Fata, J. E.; Leake, D.; Godden, E. L. Albertson, D. G.; Nieto, M. A.; Werb, Z.; Bissell, M. J. Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature 2005, 436, 123-127.
-
(2005)
Nature
, vol.436
, pp. 123-127
-
-
Radisky, D.C.1
Levy, D.D.2
Littlepage, L.E.3
Liu, H.4
Nelson, C.M.5
Fata, J.E.6
Leake, D.7
Godden, E.L.8
Albertson, D.G.9
Nieto, M.A.10
Werb, Z.11
Bissell, M.J.12
-
94
-
-
84898006693
-
Mammary epithelial cell interactions with fibronectin stimulate epithelial-mesenchymal transition
-
[Epub ahead of print]
-
Park, J.; Schwarzbauer, J. E. Mammary epithelial cell interactions with fibronectin stimulate epithelial-mesenchymal transition. Oncogene 2013. [Epub ahead of print]
-
(2013)
Oncogene
-
-
Park, J.1
Schwarzbauer, J.E.2
-
95
-
-
82455191552
-
Epigenetic regulation of mucin genes in human cancers
-
Yamada, N.; Kitamoto, S.; Yokoyama, S.; Hamada, T.; Goto, M.; Tsutsumida, H.; Higashi, M.; Yonezawa, S. Epigenetic regulation of mucin genes in human cancers. Clin. Epigenetics 2011, 2, 85-96.
-
(2011)
Clin. Epigenetics
, vol.2
, pp. 85-96
-
-
Yamada, N.1
Kitamoto, S.2
Yokoyama, S.3
Hamada, T.4
Goto, M.5
Tsutsumida, H.6
Higashi, M.7
Yonezawa, S.8
|