메뉴 건너뛰기




Volumn 68, Issue 7, 2008, Pages 2065-2070

MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUCIN 4; SMALL INTERFERING RNA;

EID: 42049105135     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-6041     Document Type: Article
Times cited : (146)

References (20)
  • 1
    • 34547854801 scopus 로고    scopus 로고
    • The oncogene HER2: Its signaling and transforming functions and its role in human cancer pathogenesis
    • Moasser MM. The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis. Oncogene 2007;26:6469-87.
    • (2007) Oncogene , vol.26 , pp. 6469-6487
    • Moasser, M.M.1
  • 2
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005;5:341-54.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 3
    • 33645130990 scopus 로고    scopus 로고
    • Signaling through ERBB receptors: Multiple layers of diversity and control
    • Warren CM, Landgraf R. Signaling through ERBB receptors: multiple layers of diversity and control. Cell Signal 2006;18:923-33.
    • (2006) Cell Signal , vol.18 , pp. 923-933
    • Warren, C.M.1    Landgraf, R.2
  • 4
    • 0033605267 scopus 로고    scopus 로고
    • An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling
    • Carraway KL III, Rossi EA, Komatsu M, et al. An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling. J Biol Chem 1999;274:5263-6.
    • (1999) J Biol Chem , vol.274 , pp. 5263-5266
    • Carraway III, K.L.1    Rossi, E.A.2    Komatsu, M.3
  • 5
    • 0037168129 scopus 로고    scopus 로고
    • Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinase B/Akt pathways
    • Jepson S, Komatsu M, Haq B, et al. Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinase B/Akt pathways. Oncogene 2002;21:7524-32.
    • (2002) Oncogene , vol.21 , pp. 7524-7532
    • Jepson, S.1    Komatsu, M.2    Haq, B.3
  • 6
    • 1642475141 scopus 로고    scopus 로고
    • Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis
    • Singh AP, Moniaux N, Chauhan SC, Meza JL, Batra SK. Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis. Cancer Res 2004;64:622-30.
    • (2004) Cancer Res , vol.64 , pp. 622-630
    • Singh, A.P.1    Moniaux, N.2    Chauhan, S.C.3    Meza, J.L.4    Batra, S.K.5
  • 7
    • 34248218177 scopus 로고    scopus 로고
    • MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins
    • Chaturvedi P, Singh AP, Moniaux N, et al. MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins. Mol Cancer Res 2007;5:309-20.
    • (2007) Mol Cancer Res , vol.5 , pp. 309-320
    • Chaturvedi, P.1    Singh, A.P.2    Moniaux, N.3
  • 8
    • 33846658776 scopus 로고    scopus 로고
    • Emerging roles of MUC4 in cancer: A novel target for diagnosis and therapy
    • Singh AP, Chaturvedi P, Batra SK. Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy. Cancer Res 2007;67:433-6.
    • (2007) Cancer Res , vol.67 , pp. 433-436
    • Singh, A.P.1    Chaturvedi, P.2    Batra, S.K.3
  • 9
    • 0742305197 scopus 로고    scopus 로고
    • Generation and characterization of anti-MUC4 monoclonal antibodies reactive with normal and cancer cells in humans
    • Moniaux N, Varshney GC, Chauhan SC, et al. Generation and characterization of anti-MUC4 monoclonal antibodies reactive with normal and cancer cells in humans. J Histochem Cytochem 2004;52:253-61.
    • (2004) J Histochem Cytochem , vol.52 , pp. 253-261
    • Moniaux, N.1    Varshney, G.C.2    Chauhan, S.C.3
  • 10
    • 33747883766 scopus 로고    scopus 로고
    • Cell surface-associated mucins in signal transduction
    • Singh PK, Hollingsworth MA. Cell surface-associated mucins in signal transduction. Trends Cell Biol 2006;16:467-76.
    • (2006) Trends Cell Biol , vol.16 , pp. 467-476
    • Singh, P.K.1    Hollingsworth, M.A.2
  • 11
    • 33845296622 scopus 로고    scopus 로고
    • MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling
    • Ren J, Raina D, Chen W, Li G, Huang L, Kufe D. MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling. Mol Cancer Res 2006;4:873-83.
    • (2006) Mol Cancer Res , vol.4 , pp. 873-883
    • Ren, J.1    Raina, D.2    Chen, W.3    Li, G.4    Huang, L.5    Kufe, D.6
  • 12
    • 33947224631 scopus 로고    scopus 로고
    • MUC1 is a novel regulator of ErbB1 receptor trafficking
    • Pochampalli MR, el Bejjani RM, Schroeder JA. MUC1 is a novel regulator of ErbB1 receptor trafficking. Oncogene 2007;26:1693-701.
    • (2007) Oncogene , vol.26 , pp. 1693-1701
    • Pochampalli, M.R.1    el Bejjani, R.M.2    Schroeder, J.A.3
  • 13
    • 34748902247 scopus 로고    scopus 로고
    • The MUC1 and galectin-3 oncoproteins function in a MicroRNA-dependent regulatory loop
    • Ramasamy S, Duraisamy S, Barbashov S, Kawano T, Kharbanda S, Kufe D. The MUC1 and galectin-3 oncoproteins function in a MicroRNA-dependent regulatory loop. Mol Cell 2007;27:992-1004.
    • (2007) Mol Cell , vol.27 , pp. 992-1004
    • Ramasamy, S.1    Duraisamy, S.2    Barbashov, S.3    Kawano, T.4    Kharbanda, S.5    Kufe, D.6
  • 14
    • 1342323632 scopus 로고    scopus 로고
    • ErbB receptors: Directing key signaling networks throughout life
    • Holbro T, Hynes NE. ErbB receptors: directing key signaling networks throughout life. Annu Rev Pharmacol Toxicol 2004;44:195-217.
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 15
    • 0032510109 scopus 로고    scopus 로고
    • Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes
    • Amundadottir LT, Leder P. Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes. Oncogene 1998;16:737-46.
    • (1998) Oncogene , vol.16 , pp. 737-746
    • Amundadottir, L.T.1    Leder, P.2
  • 16
    • 0028229715 scopus 로고
    • A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway
    • Ben-Levy R, Paterson HF, Marshall CJ, Yarden Y. A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway. EMBO J 1994;13:3302-11.
    • (1994) EMBO J , vol.13 , pp. 3302-3311
    • Ben-Levy, R.1    Paterson, H.F.2    Marshall, C.J.3    Yarden, Y.4
  • 17
    • 0842320996 scopus 로고    scopus 로고
    • Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells
    • Seton-Rogers SE, Lu Y, Hines LM, et al. Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells. Proc Natl Acad Sci U S A 2004;101:1257-62.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1257-1262
    • Seton-Rogers, S.E.1    Lu, Y.2    Hines, L.M.3
  • 18
    • 0037179871 scopus 로고    scopus 로고
    • Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells
    • Timms JF, White SL, O'Hare MJ, Waterfield MD. Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells. Oncogene 2002;21:6573-86.
    • (2002) Oncogene , vol.21 , pp. 6573-6586
    • Timms, J.F.1    White, S.L.2    O'Hare, M.J.3    Waterfield, M.D.4
  • 19
    • 0029120440 scopus 로고
    • Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
    • Ilic D, Furuta Y, Kanazawa S, et al. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 1995;377:539-44.
    • (1995) Nature , vol.377 , pp. 539-544
    • Ilic, D.1    Furuta, Y.2    Kanazawa, S.3
  • 20
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion-dependent cell survival by focal adhesion kinase
    • Frisch SM, Vuori K, Ruoslahti E, Chan-Hui PY. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996;134:793-9.
    • (1996) J Cell Biol , vol.134 , pp. 793-799
    • Frisch, S.M.1    Vuori, K.2    Ruoslahti, E.3    Chan-Hui, P.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.