Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer

Cancer Research

Volumn 71, Issue 22, 2011, Pages 7061-7070

  Yoo, Young A ^a   Kang, Myoung Hee ^b   Lee, Hyun Joo ^a   Kim, Baek Hui ^a   Park, Jong Kuk ^c   Kim, Hyun Koo ^a   Kim, Jun Suk ^a   Oh, Sang Cheul ^a  

^a Korea University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Korea Institute of Radiation and Medical Science   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; PROTEIN KINASE B; SONIC HEDGEHOG PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER INCIDENCE; CANCER INVASION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; LYMPHANGIOGENESIS; MAJOR CLINICAL STUDY; MALE; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR BIOPSY; TUMOR XENOGRAFT;

ADULT; AGED; ANIMALS; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HEDGEHOG PROTEINS; HUMANS; LYMPHANGIOGENESIS; LYMPHATIC METASTASIS; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 81155126047     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-1338     Document Type: Article

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