메뉴 건너뛰기




Volumn 15, Issue 12, 2013, Pages

Flavonoids from fruit and vegetables: A focus on cardiovascular risk factors

Author keywords

Blood lipids; Blood pressure; Cardiovascular risk; Flavonoids; Fruit and vegetables; Vascular function

Indexed keywords

ANTHOCYANIN; APPLE FLAVONOID; ATORVASTATIN; AURANTIIN; BERRY FLAVONOID; BIOFLAVONOID; BIOLOGICAL MARKER; CRANBERRY EXTRACT; EPICATECHIN; FLAVAN DERIVATIVE; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; FLUINDOSTATIN; HESPERETIN; HESPERIDIN; ISOFLAVONE DERIVATIVE; NARINGENIN; ONION FLAVONOID; PLACEBO; POLYPHENOL; PRAVASTATIN; QUERCETIN; SIMVASTATIN; UNCLASSIFIED DRUG; PLANT EXTRACT;

EID: 84890535643     PISSN: 15233804     EISSN: 15346242     Source Type: Journal    
DOI: 10.1007/s11883-013-0368-y     Document Type: Article
Times cited : (83)

References (55)
  • 1
    • 84865097262 scopus 로고    scopus 로고
    • Flavonoid basics: Chemistry, sources, mechanisms of action, and safety
    • 10.1080/21551197.2012.698219 22888837 10.1080/21551197.2012.698219 This article offers comprehensive information on flavonoids, along with details on flavonoid content in various important food sources
    • •• Corcoran MP, McKay DL, Blumberg JB. Flavonoid basics: chemistry, sources, mechanisms of action, and safety. J Nutr Gerontol Geriatr. 2012;31(3):176-89. doi: 10.1080/21551197.2012.698219. This article offers comprehensive information on flavonoids, along with details on flavonoid content in various important food sources.
    • (2012) J Nutr Gerontol Geriatr , vol.31 , Issue.3 , pp. 176-189
    • Corcoran, M.P.1    McKay, D.L.2    Blumberg, J.B.3
  • 2
    • 0027504187 scopus 로고
    • Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen elderly study
    • 8105262 10.1016/0140-6736(93)92876-U 1:STN:280:DyaK2c%2FhvVajsQ%3D%3D
    • Hertog MG, Feskens EJ, Hollman PC, et al. Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen elderly study. Lancet. 1993;342(8878):1007-11.
    • (1993) Lancet , vol.342 , Issue.8878 , pp. 1007-1011
    • Hertog, M.G.1    Feskens, E.J.2    Hollman, P.C.3
  • 3
    • 33847789892 scopus 로고    scopus 로고
    • Flavonoid intake and cardiovascular disease mortality: A prospective study in postmenopausal women
    • 17344514 1:CAS:528:DC%2BD2sXjtleqtbc%3D
    • Mink PJ, Scrafford CG, Barraj LM, et al. Flavonoid intake and cardiovascular disease mortality: A prospective study in postmenopausal women. Am J Clin Nutr. 2007;85(3):895-909.
    • (2007) Am J Clin Nutr , vol.85 , Issue.3 , pp. 895-909
    • Mink, P.J.1    Scrafford, C.G.2    Barraj, L.M.3
  • 4
    • 34748907232 scopus 로고    scopus 로고
    • The intake of flavonoids and carotid atherosclerosis: The Kuopio ischaemic heart disease risk factor study
    • 10.1017/S0007114507744410 17466095 10.1017/S0007114507744410 1:CAS:528:DC%2BD2sXhtlWhsrnN
    • Mursu J, Nurmi T, Tuomainen TP, et al. The intake of flavonoids and carotid atherosclerosis: The Kuopio ischaemic heart disease risk factor study. Br J Nutr. 2007;98(4):814-8. doi: 10.1017/S0007114507744410.
    • (2007) Br J Nutr , vol.98 , Issue.4 , pp. 814-818
    • Mursu, J.1    Nurmi, T.2    Tuomainen, T.P.3
  • 5
    • 79251498922 scopus 로고    scopus 로고
    • Habitual intake of flavonoid subclasses and incident hypertension in adults
    • 10.3945/ajcn.110.006783 21106916 10.3945/ajcn.110.006783 1:CAS:528:DC%2BC3MXhs1Cksro%3D
    • Cassidy A, O'Reilly EJ, Kay C, et al. Habitual intake of flavonoid subclasses and incident hypertension in adults. Am J Clin Nutr. 2011;93(2):338-47. doi: 10.3945/ajcn.110.006783.
    • (2011) Am J Clin Nutr , vol.93 , Issue.2 , pp. 338-347
    • Cassidy, A.1    O'Reilly, E.J.2    Kay, C.3
  • 6
    • 84867930002 scopus 로고    scopus 로고
    • Relative impact of flavonoid composition, dose and structure on vascular function: A systematic review of randomised controlled trials of flavonoid-rich food products
    • 10.1002/mnfr.201200363 22996837 10.1002/mnfr.201200363 1:CAS:528:DC%2BC38XhtlKisbrP
    • Kay CD, Hooper L, Kroon PA, et al. Relative impact of flavonoid composition, dose and structure on vascular function: A systematic review of randomised controlled trials of flavonoid-rich food products. Mol Nutr Food Res. 2012;56(11):1605-16. doi: 10.1002/mnfr.201200363.
    • (2012) Mol Nutr Food Res , vol.56 , Issue.11 , pp. 1605-1616
    • Kay, C.D.1    Hooper, L.2    Kroon, P.A.3
  • 7
    • 77952769142 scopus 로고    scopus 로고
    • Antiatherogenic properties of flavonoids: Implications for cardiovascular health
    • 20386755 10.1016/S0828-282X(10)71056-4 1:CAS:528:DC%2BC3cXltV2nt7k%3D
    • Mulvihill EE, Huff MW. Antiatherogenic properties of flavonoids: Implications for cardiovascular health. Can J Cardiol. 2010;26(A):17A-21A.
    • (2010) Can J Cardiol , vol.26 , Issue.A
    • Mulvihill, E.E.1    Huff, M.W.2
  • 8
    • 79951711056 scopus 로고    scopus 로고
    • Modulation of platelet function and signaling by flavonoids
    • 21222578 10.2174/138955711794519537
    • El Haouari M, Rosado JA. Modulation of platelet function and signaling by flavonoids. Mini Rev Med Chem. 2011;11(2):131-42.
    • (2011) Mini Rev Med Chem , vol.11 , Issue.2 , pp. 131-142
    • El Haouari, M.1    Rosado, J.A.2
  • 9
    • 84880286634 scopus 로고    scopus 로고
    • Flavonoids in atherosclerosis: An overview of their mechanisms of action
    • 23627935 10.2174/0929867311320210003 1:CAS:528:DC%2BC3sXhtFShsb%2FF
    • Siasos G, Tousoulis D, Tsigkou V, et al. Flavonoids in atherosclerosis: An overview of their mechanisms of action. Curr Med Chem. 2013;20(21):2641-60.
    • (2013) Curr Med Chem , vol.20 , Issue.21 , pp. 2641-2660
    • Siasos, G.1    Tousoulis, D.2    Tsigkou, V.3
  • 10
    • 79951683262 scopus 로고    scopus 로고
    • Effects of resveratrol and other wine polyphenols on vascular function: An update
    • 10.1016/j.jnutbio.2010.07.004 21111592 10.1016/j.jnutbio.2010.07.004 1:CAS:528:DC%2BC3MXit12js7c%3D
    • Gresele P, Cerletti C, Guglielmini G, et al. Effects of resveratrol and other wine polyphenols on vascular function: An update. J Nutr Biochem. 2011;22(3):201-11. doi: 10.1016/j.jnutbio.2010.07.004.
    • (2011) J Nutr Biochem , vol.22 , Issue.3 , pp. 201-211
    • Gresele, P.1    Cerletti, C.2    Guglielmini, G.3
  • 11
    • 33750342645 scopus 로고    scopus 로고
    • Endothelial function, nitric oxide, and cocoa flavanols
    • 16794450 10.1097/00005344-200606001-00007 1:CAS:528:DC%2BD28XmtVOkt70%3D discussion S72-6
    • Heiss C, Schroeter H, Balzer J, et al. Endothelial function, nitric oxide, and cocoa flavanols. J Cardiovasc Pharmacol. 2006;47(2):S128-35. discussion S72-6.
    • (2006) J Cardiovasc Pharmacol , vol.47 , Issue.2 , pp. 128-135
    • Heiss, C.1    Schroeter, H.2    Balzer, J.3
  • 12
    • 65649100099 scopus 로고    scopus 로고
    • Flavonoids, vascular function and cardiovascular protection
    • 19355949 10.2174/138161209787846982 1:CAS:528:DC%2BD1MXktlSlsrY%3D
    • Grassi D, Desideri G, Croce G, et al. Flavonoids, vascular function and cardiovascular protection. Curr Pharm Des. 2009;15(10):1072-84.
    • (2009) Curr Pharm des , vol.15 , Issue.10 , pp. 1072-1084
    • Grassi, D.1    Desideri, G.2    Croce, G.3
  • 13
    • 70350703413 scopus 로고    scopus 로고
    • Fruits, vegetables and coronary heart disease
    • 10.1038/nrcardio.2009.131 19652655 10.1038/nrcardio.2009.131
    • Dauchet L, Amouyel P, Dallongeville J. Fruits, vegetables and coronary heart disease. Nat Rev Cardiol. 2009;6(9):599-608. doi: 10.1038/nrcardio.2009. 131.
    • (2009) Nat Rev Cardiol , vol.6 , Issue.9 , pp. 599-608
    • Dauchet, L.1    Amouyel, P.2    Dallongeville, J.3
  • 14
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • 10.1038/35025203 11001066 10.1038/35025203 1:CAS:528:DC%2BD3cXmvVSlsrk%3D
    • Lusis AJ. Atherosclerosis. Nature. 2000;407(6801):233-41. doi: 10.1038/35025203.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 233-241
    • Lusis, A.J.1
  • 15
    • 0025347391 scopus 로고
    • Blood pressure, stroke, and coronary heart disease. Part 2, short-term reductions in blood pressure: Overview of randomised drug trials in their epidemiological context
    • 1969567 10.1016/0140-6736(90)90944-Z 1:STN:280:DyaK3c3gsFeruw%3D%3D
    • Collins R, Peto R, MacMahon S, et al. Blood pressure, stroke, and coronary heart disease. Part 2, short-term reductions in blood pressure: Overview of randomised drug trials in their epidemiological context. Lancet. 1990;335(8693):827-38.
    • (1990) Lancet , vol.335 , Issue.8693 , pp. 827-838
    • Collins, R.1    Peto, R.2    Macmahon, S.3
  • 16
    • 34447333367 scopus 로고    scopus 로고
    • Hyperlipidaemia and cardiovascular disease
    • 10.1097/MOL.0b013e32823bcb28 17620866 10.1097/MOL.0b013e32823bcb28 1:CAS:528:DC%2BD2sXnsVCku7o%3D
    • Aviram M. Hyperlipidaemia and cardiovascular disease. Curr Opin Lipidol. 2007;18(4):473-5. doi: 10.1097/MOL.0b013e32823bcb28.
    • (2007) Curr Opin Lipidol , vol.18 , Issue.4 , pp. 473-475
    • Aviram, M.1
  • 17
    • 0037031310 scopus 로고    scopus 로고
    • Endothelial function: A barometer for cardiovascular risk?
    • 12163419 10.1161/01.CIR.0000028581.07992.56
    • Vita JA, Keaney Jr JF. Endothelial function: A barometer for cardiovascular risk? Circulation. 2002;106(6):640-2.
    • (2002) Circulation , vol.106 , Issue.6 , pp. 640-642
    • Vita, J.A.1    Keaney, Jr.J.F.2
  • 18
    • 0035177827 scopus 로고    scopus 로고
    • Phenol antioxidant quantity and quality in foods: Fruits
    • 11714322 10.1021/jf0009293 1:CAS:528:DC%2BD3MXntFymtb8%3D
    • Vinson JA, Su X, Zubik L, Bose P. Phenol antioxidant quantity and quality in foods: Fruits. J Agric Food Chem. 2001;49(11):5315-21.
    • (2001) J Agric Food Chem , vol.49 , Issue.11 , pp. 5315-5321
    • Vinson, J.A.1    Su, X.2    Zubik, L.3    Bose, P.4
  • 19
    • 1842290326 scopus 로고    scopus 로고
    • Dietary flavonoids and the risk of lung cancer and other malignant neoplasms
    • 9247006 10.1093/oxfordjournals.aje.a009257 1:STN:280:DyaK2szovF2mtg%3D%3D
    • Knekt P, Jarvinen R, Seppanen R, et al. Dietary flavonoids and the risk of lung cancer and other malignant neoplasms. Am J Epidemiol. 1997;146(3):223-30.
    • (1997) Am J Epidemiol , vol.146 , Issue.3 , pp. 223-230
    • Knekt, P.1    Jarvinen, R.2    Seppanen, R.3
  • 20
    • 84655167655 scopus 로고    scopus 로고
    • Flavonoid-rich apples and nitrate-rich spinach augment nitric oxide status and improve endothelial function in healthy men and women: A randomized controlled trial
    • 10.1016/j.freeradbiomed.2011.09.028 22019438 10.1016/j.freeradbiomed. 2011.09.028 1:CAS:528:DC%2BC38XitlylsQ%3D%3D
    • Bondonno CP, Yang X, Croft KD, et al. Flavonoid-rich apples and nitrate-rich spinach augment nitric oxide status and improve endothelial function in healthy men and women: a randomized controlled trial. Free Radic Biol Med. 2012;52(1):95-102. doi: 10.1016/j.freeradbiomed.2011.09.028.
    • (2012) Free Radic Biol Med , vol.52 , Issue.1 , pp. 95-102
    • Bondonno, C.P.1    Yang, X.2    Croft, K.D.3
  • 21
    • 77957833229 scopus 로고    scopus 로고
    • The regular consumption of a polyphenol-rich apple does not influence endothelial function: A randomised double-blind trial in hypercholesterolemic adults
    • 10.1038/ejcn.2010.135 20683465 10.1038/ejcn.2010.135 1:CAS:528: DC%2BC3cXht1Cgt7%2FJ
    • Auclair S, Chironi G, Milenkovic D, et al. The regular consumption of a polyphenol-rich apple does not influence endothelial function: A randomised double-blind trial in hypercholesterolemic adults. Eur J Clin Nutr. 2010;64(10):1158-65. doi: 10.1038/ejcn.2010.135.
    • (2010) Eur J Clin Nutr , vol.64 , Issue.10 , pp. 1158-1165
    • Auclair, S.1    Chironi, G.2    Milenkovic, D.3
  • 22
    • 79952719879 scopus 로고    scopus 로고
    • Effects of apple consumption on lipid profile of hyperlipidemic and overweight men
    • 21603015
    • Vafa MR, Haghighatjoo E, Shidfar F, et al. Effects of apple consumption on lipid profile of hyperlipidemic and overweight men. Int J Prev Med. 2011;2(2):94-100.
    • (2011) Int J Prev Med , vol.2 , Issue.2 , pp. 94-100
    • Vafa, M.R.1    Haghighatjoo, E.2    Shidfar, F.3
  • 23
    • 38449117476 scopus 로고    scopus 로고
    • Apple polyphenols influence cholesterol metabolism in healthy subjects with relatively high body mass index
    • 17898508 10.5650/jos.56.417 1:CAS:528:DC%2BD2sXosVOisrs%3D
    • Nagasako-Akazome Y, Kanda T, Ohtake Y, et al. Apple polyphenols influence cholesterol metabolism in healthy subjects with relatively high body mass index. J Oleo Sci. 2007;56(8):417-28.
    • (2007) J Oleo Sci , vol.56 , Issue.8 , pp. 417-428
    • Nagasako-Akazome, Y.1    Kanda, T.2    Ohtake, Y.3
  • 24
    • 84890565437 scopus 로고    scopus 로고
    • Intake of whole apples or clear apple juice has contrasting effects on plasma lipids in healthy volunteers
    • 10.1007/s00394-012-0489-z 23271615 This article looks at the effects of food processing on the flavonoid content of apples and the subsequent effect on CVD risk factors. The results revealed that besides flavonoids, the lack of soluble pectins in clear apple juice as compared with whole apples also had a role to play in improving the lipid profile of the subjects
    • • Ravn-Haren G, Dragsted LO, Buch-Andersen T, et al. Intake of whole apples or clear apple juice has contrasting effects on plasma lipids in healthy volunteers. Eur J Nutr. 2012. doi: 10.1007/s00394-012-0489-z. This article looks at the effects of food processing on the flavonoid content of apples and the subsequent effect on CVD risk factors. The results revealed that besides flavonoids, the lack of soluble pectins in clear apple juice as compared with whole apples also had a role to play in improving the lipid profile of the subjects.
    • (2012) Eur J Nutr
    • Ravn-Haren, G.1    Dragsted, L.O.2    Buch-Andersen, T.3
  • 25
    • 34247468812 scopus 로고    scopus 로고
    • Citrus flavonoids: Molecular structure, biological activity and nutritional properties: A review
    • 10.1016/j.foodchem.2006.11.054 10.1016/j.foodchem.2006.11.054 1:CAS:528:DC%2BD2sXkvFagt7o%3D
    • Tripoli E, Guardia ML, Giammanco S, et al. Citrus flavonoids: molecular structure, biological activity and nutritional properties: A review. Food Chem. 2007;104(2):466-79. doi: 10.1016/j.foodchem.2006.11.054.
    • (2007) Food Chem , vol.104 , Issue.2 , pp. 466-479
    • Tripoli, E.1    Guardia, M.L.2    Giammanco, S.3
  • 26
    • 78651304738 scopus 로고    scopus 로고
    • Hesperidin contributes to the vascular protective effects of orange juice: A randomized crossover study in healthy volunteers
    • 10.3945/ajcn.110.004945 21068346 10.3945/ajcn.110.004945 1:CAS:528:DC%2BC3MXls1CksA%3D%3D
    • Morand C, Dubray C, Milenkovic D, et al. Hesperidin contributes to the vascular protective effects of orange juice: A randomized crossover study in healthy volunteers. Am J Clin Nutr. 2011;93(1):73-80. doi: 10.3945/ajcn.110. 004945.
    • (2011) Am J Clin Nutr , vol.93 , Issue.1 , pp. 73-80
    • Morand, C.1    Dubray, C.2    Milenkovic, D.3
  • 27
    • 79955655412 scopus 로고    scopus 로고
    • Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome
    • 10.1210/jc.2010-2879 21346065 10.1210/jc.2010-2879 1:CAS:528: DC%2BC3MXmsVWntrs%3D
    • Rizza S, Muniyappa R, Iantorno M, et al. Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome. J Clin Endocrinol Metab. 2011;96(5):E782-92. doi: 10.1210/jc.2010-2879.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.5 , pp. 782-792
    • Rizza, S.1    Muniyappa, R.2    Iantorno, M.3
  • 28
    • 2942604944 scopus 로고    scopus 로고
    • Preventive effects of diets supplemented with sweetie fruits in hypercholesterolemic patients suffering from coronary artery disease
    • 10.1016/j.ypmed.2003.12.021 15193907 10.1016/j.ypmed.2003.12.021
    • Gorinstein S, Caspi A, Libman I, et al. Preventive effects of diets supplemented with sweetie fruits in hypercholesterolemic patients suffering from coronary artery disease. Prev Med. 2004;38(6):841-7. doi: 10.1016/j.ypmed.2003. 12.021.
    • (2004) Prev Med , vol.38 , Issue.6 , pp. 841-847
    • Gorinstein, S.1    Caspi, A.2    Libman, I.3
  • 29
    • 33645453199 scopus 로고    scopus 로고
    • Red grapefruit positively influences serum triglyceride level in patients suffering from coronary atherosclerosis: Studies in vitro and in humans
    • 10.1021/jf058171g 16506849 10.1021/jf058171g 1:CAS:528: DC%2BD28XpvFGgtA%3D%3D
    • Gorinstein S, Caspi A, Libman I, et al. Red grapefruit positively influences serum triglyceride level in patients suffering from coronary atherosclerosis: studies in vitro and in humans. J Agric Food Chem. 2006;54(5):1887-92. doi: 10.1021/jf058171g.
    • (2006) J Agric Food Chem , vol.54 , Issue.5 , pp. 1887-1892
    • Gorinstein, S.1    Caspi, A.2    Libman, I.3
  • 30
    • 0031255282 scopus 로고    scopus 로고
    • Phytochemicals: Guardians of our health
    • 9336591 10.1016/S0002-8223(97)00765-7 1:CAS:528:DyaK2sXmvFyqs7c%3D
    • Craig WJ. Phytochemicals: Guardians of our health. J Am Diet Assoc. 1997;97(10 Suppl 2):S199-204.
    • (1997) J Am Diet Assoc , vol.97 , Issue.10 SUPPL. 2 , pp. 199-204
    • Craig, W.J.1
  • 31
    • 0345256647 scopus 로고    scopus 로고
    • Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects
    • 14613759 10.1016/S0261-5614(03)00059-1 1:CAS:528:DC%2BD3sXovVeitbc%3D
    • Jung UJ, Kim HJ, Lee JS, et al. Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects. Clin Nutr. 2003;22(6):561-8.
    • (2003) Clin Nutr , vol.22 , Issue.6 , pp. 561-568
    • Jung, U.J.1    Kim, H.J.2    Lee, J.S.3
  • 32
    • 77956582061 scopus 로고    scopus 로고
    • The citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and women
    • 10.3945/jn.110.124735 20660284 10.3945/jn.110.124735 1:CAS:528: DC%2BC3cXhtFajurnK
    • Demonty I, Lin Y, Zebregs YE, et al. The citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and women. J Nutr. 2010;140(9):1615-20. doi: 10.3945/jn.110.124735.
    • (2010) J Nutr , vol.140 , Issue.9 , pp. 1615-1620
    • Demonty, I.1    Lin, Y.2    Zebregs, Y.E.3
  • 33
    • 84875880840 scopus 로고    scopus 로고
    • A more balanced approach to drug-grapefruit juice interactions
    • 10.1136/bmj.f1073 23444431 10.1136/bmj.f1073
    • Backman WD, Bakhai A. A more balanced approach to drug-grapefruit juice interactions. BMJ. 2013;346:f1073. doi: 10.1136/bmj.f1073.
    • (2013) BMJ. , vol.346 , pp. 1073
    • Backman, W.D.1    Bakhai, A.2
  • 34
    • 77953673295 scopus 로고    scopus 로고
    • Berries: Emerging impact on cardiovascular health
    • 10.1111/j.1753-4887.2010.00273.x 20384847 10.1111/j.1753-4887.2010.00273. x
    • Basu A, Rhone M, Lyons TJ. Berries: Emerging impact on cardiovascular health. Nutr Rev. 2010;68(3):168-77. doi: 10.1111/j.1753-4887.2010.00273.x.
    • (2010) Nutr Rev , vol.68 , Issue.3 , pp. 168-177
    • Basu, A.1    Rhone, M.2    Lyons, T.J.3
  • 35
    • 38949148660 scopus 로고    scopus 로고
    • Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol
    • 18258621 1:CAS:528:DC%2BD1cXitFajsb4%3D
    • Erlund I, Koli R, Alfthan G, et al. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr. 2008;87(2):323-31.
    • (2008) Am J Clin Nutr , vol.87 , Issue.2 , pp. 323-331
    • Erlund, I.1    Koli, R.2    Alfthan, G.3
  • 36
    • 77956590596 scopus 로고    scopus 로고
    • Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome
    • 10.3945/jn.110.124701 20660279 10.3945/jn.110.124701 1:CAS:528: DC%2BC3cXhtFajurnN
    • Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr. 2010;140(9):1582-7. doi: 10.3945/jn.110.124701.
    • (2010) J Nutr , vol.140 , Issue.9 , pp. 1582-1587
    • Basu, A.1    Du, M.2    Leyva, M.J.3
  • 37
    • 84866607468 scopus 로고    scopus 로고
    • Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women
    • 10.3945/ajcn.112.042036 22914551 10.3945/ajcn.112.042036 1:CAS:528:DC%2BC38XhsVCku7zF
    • Jennings A, Welch AA, Fairweather-Tait SJ, et al. Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women. Am J Clin Nutr. 2012;96(4):781-8. doi: 10.3945/ajcn.112.042036.
    • (2012) Am J Clin Nutr , vol.96 , Issue.4 , pp. 781-788
    • Jennings, A.1    Welch, A.A.2    Fairweather-Tait, S.J.3
  • 38
    • 34548062593 scopus 로고    scopus 로고
    • Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults
    • 17634269 1:CAS:528:DC%2BD2sXos1Cktbc%3D
    • Karlsen A, Retterstol L, Laake P, et al. Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. J Nutr. 2007;137(8):1951-4.
    • (2007) J Nutr , vol.137 , Issue.8 , pp. 1951-1954
    • Karlsen, A.1    Retterstol, L.2    Laake, P.3
  • 39
    • 38049102766 scopus 로고    scopus 로고
    • Low-calorie cranberry juice supplementation reduces plasma oxidized LDL and cell adhesion molecule concentrations in men
    • 10.1017/S0007114507811986 17761017 10.1017/S0007114507811986 1:CAS:528:DC%2BD1cXhs1CktL0%3D
    • Ruel G, Pomerleau S, Couture P, et al. Low-calorie cranberry juice supplementation reduces plasma oxidized LDL and cell adhesion molecule concentrations in men. Br J Nutr. 2008;99(2):352-9. doi: 10.1017/ S0007114507811986.
    • (2008) Br J Nutr , vol.99 , Issue.2 , pp. 352-359
    • Ruel, G.1    Pomerleau, S.2    Couture, P.3
  • 40
    • 77955974733 scopus 로고    scopus 로고
    • Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome
    • 10.1016/j.nutres.2010.06.016 20797478 10.1016/j.nutres.2010.06.016 1:CAS:528:DC%2BC3cXhtV2hurzK The article discusses several aspects of metabolic syndrome, and provides important findings that support the benefits of strawberries in improving metabolic syndrome
    • • Basu A, Fu DX, Wilkinson M, et al. Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome. Nutr Res. 2010;30(7):462-9. doi: 10.1016/j.nutres.2010.06.016. The article discusses several aspects of metabolic syndrome, and provides important findings that support the benefits of strawberries in improving metabolic syndrome.
    • (2010) Nutr Res , vol.30 , Issue.7 , pp. 462-469
    • Basu, A.1    Fu, D.X.2    Wilkinson, M.3
  • 41
    • 57449115355 scopus 로고    scopus 로고
    • Effect of cranberry extracts on lipid profiles in subjects with type 2 diabetes
    • 10.1111/j.1464-5491.2008.02588.x 19046248 10.1111/j.1464-5491.2008.02588. x 1:CAS:528:DC%2BD1MXht1yks7g%3D
    • Lee IT, Chan YC, Lin CW, et al. Effect of cranberry extracts on lipid profiles in subjects with type 2 diabetes. Diabet Med. 2008;25(12):1473-7. doi: 10.1111/j.1464-5491.2008.02588.x.
    • (2008) Diabet Med , vol.25 , Issue.12 , pp. 1473-1477
    • Lee, I.T.1    Chan, Y.C.2    Lin, C.W.3
  • 42
    • 84862251868 scopus 로고    scopus 로고
    • Therapeutic potential of quercetin to decrease blood pressure: Review of efficacy and mechanisms
    • 10.3945/an.111.001271 22332099 10.3945/an.111.001271 1:CAS:528: DC%2BC38XjtFGmtLs%3D
    • Larson AJ, Symons JD, Jalili T. Therapeutic potential of quercetin to decrease blood pressure: Review of efficacy and mechanisms. Adv Nutr. 2012;3(1):39-46. doi: 10.3945/an.111.001271.
    • (2012) Adv Nutr , vol.3 , Issue.1 , pp. 39-46
    • Larson, A.J.1    Symons, J.D.2    Jalili, T.3
  • 43
    • 35848966547 scopus 로고    scopus 로고
    • Quercetin reduces blood pressure in hypertensive subjects
    • 17951477 1:CAS:528:DC%2BD2sXht1ynsb3K
    • Edwards RL, Lyon T, Litwin SE, et al. Quercetin reduces blood pressure in hypertensive subjects. J Nutr. 2007;137(11):2405-11.
    • (2007) J Nutr , vol.137 , Issue.11 , pp. 2405-2411
    • Edwards, R.L.1    Lyon, T.2    Litwin, S.E.3
  • 44
    • 73749083955 scopus 로고    scopus 로고
    • Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: A double-blinded, placebo-controlled cross-over study
    • 10.1017/S0007114509359127 19402938 10.1017/S0007114509359127 1:CAS:528:DC%2BD1MXhsVSkurjP
    • Egert S, Bosy-Westphal A, Seiberl J, et al. Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: A double-blinded, placebo-controlled cross-over study. Br J Nutr. 2009;102(7):1065-74. doi: 10.1017/S0007114509359127.
    • (2009) Br J Nutr , vol.102 , Issue.7 , pp. 1065-1074
    • Egert, S.1    Bosy-Westphal, A.2    Seiberl, J.3
  • 45
    • 53849146739 scopus 로고    scopus 로고
    • Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men
    • 18842789 1:CAS:528:DC%2BD1cXht1Gks7nJ
    • Loke WM, Hodgson JM, Proudfoot JM, et al. Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men. Am J Clin Nutr. 2008;88(4):1018-25.
    • (2008) Am J Clin Nutr , vol.88 , Issue.4 , pp. 1018-1025
    • Loke, W.M.1    Hodgson, J.M.2    Proudfoot, J.M.3
  • 46
    • 77949874571 scopus 로고    scopus 로고
    • DASH lowers blood pressure in obese hypertensives beyond potassium, magnesium and fibre
    • 19626043 10.1038/jhh.2009.58 1:CAS:528:DC%2BC3cXjsFCrsr0%3D
    • Al-Solaiman Y, Jesri A, Mountford W, et al. DASH lowers blood pressure in obese hypertensives beyond potassium, magnesium and fibre. J Hum Hypertens. 2010;24(4):237-46.
    • (2010) J Hum Hypertens , vol.24 , Issue.4 , pp. 237-246
    • Al-Solaiman, Y.1    Jesri, A.2    Mountford, W.3
  • 47
    • 79951878451 scopus 로고    scopus 로고
    • Vitamin A supplementation modifies the association between mucosal innate and adaptive immune responses and resolution of enteric pathogen infections
    • 10.3945/ajcn.110.003913 21248183 10.3945/ajcn.110.003913 1:CAS:528:DC%2BC3MXivVKktL0%3D
    • Long KZ, Santos JI, Rosado JL, et al. Vitamin A supplementation modifies the association between mucosal innate and adaptive immune responses and resolution of enteric pathogen infections. Am J Clin Nutr. 2011;93(3):578-85. doi: 10.3945/ajcn.110.003913.
    • (2011) Am J Clin Nutr , vol.93 , Issue.3 , pp. 578-585
    • Long, K.Z.1    Santos, J.I.2    Rosado, J.L.3
  • 48
    • 84881346737 scopus 로고    scopus 로고
    • MicroRNAs in the diagnosis and treatment of unstable angina
    • 10.2174/15680266113139990108 1:CAS:528:DC%2BC3sXht1Wgu7fO
    • Latsios G, Tousoulis D, Androulakis E, et al. MicroRNAs in the diagnosis and treatment of unstable angina. Cur Top Med Chem. 2013;13(13):1596-604.
    • (2013) Cur Top Med Chem , vol.13 , Issue.13 , pp. 1596-1604
    • Latsios, G.1    Tousoulis, D.2    Androulakis, E.3
  • 49
    • 84881339221 scopus 로고    scopus 로고
    • Novel biomarkers assessing endothelial dysfunction: Role of miRNAs
    • 23745803 10.2174/15680266113139990100 1:CAS:528:DC%2BC3sXht1WnsbvM
    • Tousoulis D, Androulakis E, Papageorgiou N, et al. Novel biomarkers assessing endothelial dysfunction: role of miRNAs. Curr Top Med Chem. 2013;13(13):1518-26.
    • (2013) Curr Top Med Chem , vol.13 , Issue.13 , pp. 1518-1526
    • Tousoulis, D.1    Androulakis, E.2    Papageorgiou, N.3
  • 50
    • 84878179093 scopus 로고    scopus 로고
    • The impact of physical activity on endothelial function in middle-aged and elderly subjects: The Ikaria study
    • Siasos G, Chrysohoou C, Tousoulis D, et al. The impact of physical activity on endothelial function in middle-aged and elderly subjects: The Ikaria study. Hell J Cardiol. 2013;54(2):94-101.
    • (2013) Hell J Cardiol , vol.54 , Issue.2 , pp. 94-101
    • Siasos, G.1    Chrysohoou, C.2    Tousoulis, D.3
  • 51
    • 84885295315 scopus 로고    scopus 로고
    • The impact of CYP2C19 genotype on cardiovascular events and platelet reactivity in patients with coronary artery disease receiving clopidogrel
    • 10.1016/j.ijcard.2013.01.040
    • Tousoulis D, Siasos G, Zaromitidou M, et al. The impact of CYP2C19 genotype on cardiovascular events and platelet reactivity in patients with coronary artery disease receiving clopidogrel. Int J Cardiol. 2013. doi: 10.1016/j.ijcard.2013.01.040.
    • (2013) Int J Cardiol
    • Tousoulis, D.1    Siasos, G.2    Zaromitidou, M.3
  • 52
    • 80052284088 scopus 로고    scopus 로고
    • Biomarkers of fruit and vegetable intake in human intervention studies: A systematic review
    • 10.1080/10408398.2010.482217 21888531 10.1080/10408398.2010.482217 1:CAS:528:DC%2BC3MXhtlOnt7jK
    • Baldrick FR, Woodside JV, Elborn JS, et al. Biomarkers of fruit and vegetable intake in human intervention studies: A systematic review. Crit Rev Food Sci Nutr. 2011;51(9):795-815. doi: 10.1080/10408398.2010.482217.
    • (2011) Crit Rev Food Sci Nutr , vol.51 , Issue.9 , pp. 795-815
    • Baldrick, F.R.1    Woodside, J.V.2    Elborn, J.S.3
  • 53
    • 0036737867 scopus 로고    scopus 로고
    • Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables
    • 10.1038/sj.ejcn.1601409 12209378 10.1038/sj.ejcn.1601409 1:CAS:528:DC%2BD38Xms1eqsrw%3D
    • Erlund I, Silaste ML, Alfthan G, et al. Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables. Eur J Clin Nutr. 2002;56(9):891-8. doi: 10.1038/sj.ejcn.1601409.
    • (2002) Eur J Clin Nutr , vol.56 , Issue.9 , pp. 891-898
    • Erlund, I.1    Silaste, M.L.2    Alfthan, G.3
  • 54
    • 0141863402 scopus 로고    scopus 로고
    • Overview of dietary flavonoids: Nomenclature, occurrence and intake
    • 14519822 1:CAS:528:DC%2BD3sXotFKrtb4%3D
    • Beecher GR. Overview of dietary flavonoids: Nomenclature, occurrence and intake. J Nutr. 2003;133(10):3248S-54S.
    • (2003) J Nutr , vol.133 , Issue.10
    • Beecher, G.R.1
  • 55
    • 46649098436 scopus 로고    scopus 로고
    • Flavonoids, flavonoid-rich foods, and cardiovascular risk: A meta-analysis of randomized controlled trials
    • 18614722 1:CAS:528:DC%2BD1cXoslylsL4%3D
    • Hooper L, Kroon PA, Rimm EB, et al. Flavonoids, flavonoid-rich foods, and cardiovascular risk: A meta-analysis of randomized controlled trials. Am J Clin Nutr. 2008;88(1):38-50.
    • (2008) Am J Clin Nutr , vol.88 , Issue.1 , pp. 38-50
    • Hooper, L.1    Kroon, P.A.2    Rimm, E.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.