Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 69, Issue 1, 2014, Pages 13-24

  Mitterberger, Maria C ^a   Lechner, Stefan ^a   Mattesich, Monika ^b   Zwerschke, Werner ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Adipogenesis; Adipokine; Adipose derived stromal progenitor cells; Aging; C EBP ; P16Ink4A; P21Cip1; P53; PPAR 2; Proliferation; Retinoblastoma protein; Senescence

Indexed keywords

ADIPOCYTOKINE; CCAAT BINDING FACTOR; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P53; RNA;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE-DERIVED STROMAL/PROGENITOR CELLS; ADULT; AGED; AGING; ARTICLE; BIOSYNTHESIS; C/EBPΑ; CELL AGING; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MIDDLE AGED; P16INK4A; P21CIP1; PHYSIOLOGY; PPARΓ2; PROLIFERATION; RETINOBLASTOMA PROTEIN.; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; STEM CELL; STROMA CELL; WESTERN BLOTTING;

ADIPOGENESIS; ADIPOKINE; ADIPOSE-DERIVED STROMAL/PROGENITOR CELLS; AGING; C/EBPΑ; P16INK4A; P21CIP1; P53; PPARΓ2; PROLIFERATION; RETINOBLASTOMA PROTEIN.; SENESCENCE;

ADIPOCYTES; ADIPOGENESIS; ADULT; AGED; BLOTTING, WESTERN; CCAAT-BINDING FACTOR; CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MIDDLE AGED; PPAR GAMMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; STEM CELLS; STROMAL CELLS;

EID: 84890443997     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt043     Document Type: Article

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