A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes

Toxicological Sciences

Volumn 136, Issue 2, 2013, Pages 595-604

  Rowlands, J Craig ^a   Budinsky, Robert ^a   Gollapudi, Bhaskar ^a   Black, Michael B ^b   Wolfinger, Russell D ^c   Cukovic, Daniela ^d   Dombkowski, Alan ^d   Thompson, Chad M ^e   Urban, Jonathan D ^f   Thomas, Russell S ^b  

^a DOW CHEMICAL COMPANY   (United States)

^b HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^c SAS INSTITUTE INC   (United States)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ToxStrategies Inc   (United States)

^f ToxStrategies Inc   (United States)

Author keywords

aryl hydrocarbon receptor; Dioxin; Dose response; Risk assessment; Toxicogenomics

Indexed keywords

2,3,4,7,8 PENTACHLORODIBENZOFURAN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,3,7,8 TETRACHLORODIBENZOFURAN; DIBENZOFURAN DERIVATIVE; DIOXIN; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENE EXPRESSION; GENE INTERACTION; GENOMICS; LIVER CELL; NONHUMAN; RAT; SIGNAL TRANSDUCTION; WORLD HEALTH ORGANIZATION;

ARYL HYDROCARBON RECEPTOR; DIOXIN; DOSE RESPONSE; RISK ASSESSMENT.; TOXICOGENOMICS;

ANIMALS; CELLS, CULTURED; DIOXINS; FEMALE; GENE EXPRESSION REGULATION; GENOMICS; HEPATOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84890394630     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft203     Document Type: Article

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