Transcriptional profiles induced by the Aryl Hydrocarbon Receptor agonists 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran in primary rat hepatocytes

Chemosphere

Volumn 85, Issue 2, 2011, Pages 232-238

  Rowlands, J Craig ^a   Budinsky, Robert ^a   Gollapudi, Bhaskar ^a   Novak, Raymond ^b   Abdelmegeed, Mohamed ^b,c   Cukovic, Daniela ^b   Dombkowski, Alan ^b  

^a DOW CHEMICAL COMPANY   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

2,3,4,7,8 PeCDF; 2,3,7,8 TCDD; 2,3,7,8 TCDF; CYP1A; Genomics; Hepatocytes

Indexed keywords

GENE EXPRESSION; RATS;

2 , 3 , 7 , 8-TCDD; 2,3,4,7,8-PECDF; 2,3,7,8-TCDF; CYP1A; GENOMICS; HEPATOCYTES;

PRINCIPAL COMPONENT ANALYSIS;

2,3,4,7,8 PENTACHLORODIBENZOFURAN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,3,7,8 TETRACHLORODIBENZOFURAN; ALDO KETO REDUCTASE FAMILY 1 MEMBER C LIKE 2; ALDO KETO REDUCTASE FAMILY 1 MEMBER C12; ALDO KETO REDUCTASE FAMILY 1 MEMBER C13; ALPHA TOCOPHEROL TRANSFER PROTEIN; AREG PROTEIN; AROMATIC HYDROCARBON RECEPTOR; CADHERIN; CADHERIN 13; CD36 ANTIGEN; CDC42 EFFECTOR PROTEIN 5; CYTOCHROME P450 17; CYTOCHROME P450 17A1; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; DIBENZOFURAN DERIVATIVE; EREG PROTEIN; GLUCURONOSYLTRANSFERASE 1A1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INITIATION FACTOR 4E BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 2; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 5; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; NEPHRONOPHTHISIS 3 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

CHEMICAL POLLUTANT; DOSE-RESPONSE RELATIONSHIP; GENE EXPRESSION; GENOMICS; HIERARCHICAL SYSTEM; MITOCHONDRIAL DNA; PRINCIPAL COMPONENT ANALYSIS; RODENT; TCDD;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; LIVER CELL; MICROARRAY ANALYSIS; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOXICOGENETICS;

RATTUS;

EID: 80054875776     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2011.06.026     Document Type: Article

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