Acid-sensing ion channel 1a-mediated calcium influx regulates apoptosis of endplate chondrocytes in intervertebral discs

Expert Opinion on Therapeutic Targets

Volumn 18, Issue 1, 2014, Pages 1-14

  Li, Xia ^a   Wu, Fan Rong ^b   Xu, Rui Sheng ^a   Hu, Wei ^b   Jiang, Dong Lin ^a   Ji, Cheng ^a   Chen, Fei Hu ^b   Yuan, Feng Lai ^a  

^a NANTONG UNIVERSITY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Acid sensing ion channel 1a; Apoptosis; Calcium; Calcium sensitive proteases; Endplate chondrocytes; Intervertebral disc degeneration

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; ACID SENSING ION CHANNEL BLOCKING AGENT; CALCINEURIN; CALCIUM; CALPAIN; CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN BAD; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ACIDOSIS; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARTILAGE CELL; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; INHIBITION KINETICS; INTERVERTEBRAL DISK; MITOCHONDRION; NERVE ENDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT;

ACID SENSING ION CHANNELS; ANIMALS; APOPTOSIS; CALCINEURIN; CALCIUM; CELLS, CULTURED; CHONDROCYTES; GROWTH PLATE; INTERVERTEBRAL DISC; ION TRANSPORT; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 84890390392     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2014.859248     Document Type: Article

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