Blockade of acid-sensing ion channels protects articular chondrocytes from acid-induced apoptotic injury

Inflammation Research

Volumn 61, Issue 4, 2012, Pages 327-335

  Hu, Wei ^a   Chen, Fei Hu ^a   Yuan, Feng Lai ^a   Zhang, Teng Yue ^a   Wu, Fan Rong ^a   Rong, Chao ^a   Jiang, Sheng ^a   Tang, Jie ^a   Zhang, Cheng Cheng ^a   Lin, Mei Ying ^b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Acid sensing ion channels (ASICs); Amiloride; Apoptosis; Articular chondrocytes; Calcineurin; Calpain; Caspase 3

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACID SENSING ION CHANNEL; AMILORIDE; CALCINEURIN; CALCIUM ION; CALPAIN; CASPASE 3; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; PROPIDIUM IODIDE; TOLONIUM CHLORIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CARTILAGE CELL; CELL ASSAY; CELL DEATH; CELL ISOLATION; CELL LABELING; CELL PROTECTION; CELL VIABILITY; CHANNEL GATING; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNOCYTOCHEMISTRY; MALE; NICK END LABELING; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY;

AMILORIDE; ANIMALS; APOPTOSIS; CALCINEURIN; CALCIUM; CALPAIN; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; HYDROCHLORIC ACID; MALE; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 84863110452     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-011-0414-6     Document Type: Article

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