Extracellular acidification induces connective tissue growth factor production through proton-sensing receptor OGR1 in human airway smooth muscle cells

Biochemical and Biophysical Research Communications

Volumn 413, Issue 4, 2011, Pages 499-503

  Matsuzaki, Shinichi ^a   Ishizuka, Tamotsu ^a   Yamada, Hidenori ^a   Kamide, Yosuke ^a   Hisada, Takeshi ^a   Ichimonji, Isao ^a   Aoki, Haruka ^a   Yatomi, Masakiyo ^a   Komachi, Mayumi ^b   Tsurumaki, Hiroaki ^a   Ono, Akihiro ^a   Koga, Yasuhiko ^a   Dobashi, Kunio ^b   Mogi, Chihiro ^b   Sato, Koichi ^b   Tomura, Hideaki ^b   Mori, Masatomo ^a   Okajima, Fumikazu ^b  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

Airway acidification; Airway smooth muscle cell; Connective tissue growth factor; G q 11 protein; Ovarian cancer G protein coupled receptor 1

Indexed keywords

CALCIUM ION; CONNECTIVE TISSUE GROWTH FACTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INOSITOL 1,4,5 TRISPHOSPHATE; PROTON SENSING OVARIAN CANCER G PROTEIN COUPLED RECEPTOR 1; UNCLASSIFIED DRUG;

ACIDIFICATION; AIRWAY REMODELING; ARTICLE; ASTHMA; CALCIUM MOBILIZATION; CONTROLLED STUDY; EXTRACELLULAR ACIDIFICATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS;

ACIDS; AIRWAY REMODELING; CALCIUM; CONNECTIVE TISSUE GROWTH FACTOR; HUMANS; HYDROGEN-ION CONCENTRATION; INOSITOL 1,4,5-TRISPHOSPHATE; LUNG; MYOCYTES, SMOOTH MUSCLE; PEPTIDES, CYCLIC; PROTONS; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING;

EID: 80053592377     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.08.087     Document Type: Article

References (36)

1. Vignola A.M., Kips J., Bousquet J. Tissue remodeling as a feature of persistent asthma. J. Allergy Clin. Immunol. 2000, 105:1041-1053.
2. Bradham D.M., Igarashi A., Potter R.L., Grotendorst G.R. Connective tissue growth factor: a cystein-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J. Cell Biol. 1991, 114:1285-1294.
3. Fan W.H., Pech M., Karnovsky M.J. Connective tissue growth factor (CTGF) stimulates vascular smooth muscle cell growth and migration in vitro. Eur. J. Cell Biol. 2000, 79:915-923.
4. Frazier K., Williams S., Kothapalli D., Klapper H., Grotendorst G.R. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J. Invest. Dermatol. 1996, 107:404-411.
5. Minshall E.M., Leung D.Y., Martin R.J., Song Y.L., Cameron L., Ernst P., Hamid Q. Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. Am. J. Respir. Cell Mol. Biol. 1997, 17:326-333.
6. Vignola A.M., Chanez P., Chiappara G., Merendino A., Pace E., Rizo A., la Rocca A.M., Bellia V., Bonsignore G., Bousquet J. Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis. Am. J. Respir. Crit. Care Med. 1997, 156:591-599.
7. Redington A.E., Madden J., Frew A.J., Djukanovic R., Roche W.R., Holgate S.T., Howarth P.H. Transforming growth factor-beta 1 in asthma: measurement in bronchoalveolar lavage fluid. Am. J. Respir. Crit. Care Med. 1997, 156:642-647.
8. Grotendorst C.R. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev. 1997, 8:171-179.
9. Leask A., Holms A., Abraham D.J. Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis. Curr. Rheumatol. Rep. 2002, 4:136-142.
10. Duvernelle C., Freund V., Frossard N. Transforming growth factor-beta and its role in asthma. Pulm. Pharmacol. Ther. 2003, 16:181-196.
11. Burgess J.K., Johnson P.R., Ge Q., Au W.W., Poniris M.H., McParland B.E., King G., Roth M., Black J.L. Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. Am. J. Respir. Crit. Care Med. 2003, 167:71-77.
12. Kodric M., Shah A.N., Fabbri L.M., Confalonieri M. An investigation of airway acidification in asthma using induced sputum: a study of feasibility and correlation. Am. J. Respir. Crit. Care Med. 2007, 175:905-910.
13. Ricciardolo F.L., Gaston B., Hunt J. Acid stress in the pathology of asthma. J. Allergy Clin. Immunol. 2004, 113:610-619.
14. Faisy C., Planquette B., Naline E., Risse P.A., Frossard N., Fagon J.Y., Advenier C., Devillier P. Acid-induced modulation of airway basal tone and contractility: role of acid-sensing ion channels (ASICs) and TRPV1 receptor. Life Sci. 2007, 81:1094-1102.
15. Lee L.Y., Gu Q. Role of TRPV1 in inflammation-induced airway hypersensitivity. Curr. Opin. Pharmacol. 2009, 9:243-249.
16. Ludwig M.G., Vanek M., Guerini D., Gasser J.A., Jones C.E., Junker U., Hofstetter H., Wolf R.M., Seuwen K. Proton-sensing G-protein-coupled receptors. Nature 2003, 425:93-98.
17. Meyer zu Heringdorf D., Jakobs K.H. Lysophopholipid receptors: signaling, pharmacology and regulation by lysophospholipid metabolism. Biochim. Biophys. Acta 2007, 1768:923-940.
18. Seuwen K., Ludwig M.G., Wolf R.M. Receptors for protons or lipid messengers or both?. J. Recept. Signal Transduct. Res. 2006, 26:599-610.
19. Tobo M., Tomura H., Mogi C., Wang J.Q., Liu J.P., Komachi M., Damirin A., Kimura T., Murata N., Kurose H., Sato K., Okajima F. Previously postulated " ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms. Cell. Signal. 2007, 19:1745-1753.
20. Tomura H., Mogi C., Sato K., Okajima F. Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: a novel type of multi-functional receptors. Cell Signal. 2005, 17:1466-1476.
21. 2+ mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 2010, 299:L567-577.
22. Bosse Y., Maghni K., Hudson T.J. 1α,25-Dihydroxy-vitamin D3 stimulation of bronchial smooth muscle cells induces autocrine, contractility, and remodeling processes. Physiol. Genomics 2007, (29):161-168.
23. Matsuzaki S., Ishizuka T., Hisada T., Aoki H., Komachi M., Ichimonji I., Utsugi M., Ono A., Koga Y., Dobashi K., Kurose H., Tomura H., Mori M., Okajima F F. Lysophosphatidic acid inhibits CCL5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells. J. Immunol. 2010, 185:4863-4872.
24. Tomura H., Wang J.Q., Komachi M., Damirin A., Mogi C., Tobo M., Kon J., Misawa N., Sato K., Okajima F. Prostaglandin I(2) production and cAMP accumulation in response to acidic extracellular pH through OGR1 in human aortic smooth muscle cells. J. Biol. Chem. 2005, (280):34458-34464.
25. Tomura H., Wang J.Q., Liu J.P., Komachi M., Damirin A., Mogi C., Tobo M., Nochi H., Tamoto K., Im D.S., Sato K., Okajima F. Cyclooxygenase-2 expression and prostaglandin E2 production in response to acidic pH through OGR1 in a human osteoblastic cell line. J. Bone Miner. Res. 2008, 23:1129-1139.
26. Takasaki J., Saito T., Taniguchi M., Kawasaki T., Moritani Y., Hayashi K., Kobori M. A novel Galphaq/11-selective inhibitor. J. Biol. Chem. 2004, 279:47438-47445.
27. 2+ entry mediated by sore depletion, S-nitrosylation, and TRP3 channels. Comparison of coupling and function. J. Biol. Chem. 2000, 275:28562-28568.
28. K Burgess J. Connective tissue growth factor: a role in airway remodelling in asthma?. Clin. Exp. Pharmacol. Physiol. 2005, 32:988-994.
29. Johnson P.R., Burgess J.K., Ge Q., Poniris M., Boustany S., Twigg S.M., Black J.L. Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle. Am. J. Respir. Crit. Care Med. 2006, 173:32-41.
30. Halwani R., Al-Muhsen S., Al-Jahdali H., Hamid Q. Role of transforming growth factor-beta in airway remodeling in asthma. Am. J. Respir. Cell Mol. Biol. 2011, 44:127-133.
31. Atamas S.P., White B. Cytokine regulation of pulmonary fibrosis in scleroderma. Cytokine Growth Factor Rev. 2003, 14:537-550.
32. Venkatachalam K., van Rossum D.B., Patterson R.L., Ma H.-T., Gill D.L. The cellular and molecular basis of store-operated calcium entry. Nat. Cell Biol. 2002, 4:E263-E272.
33. DiCosmo B.F., Geba G.P., Picarella D., Elias J.A., Rankin J.A., Stripp B.R., Whitsett J.A., Flavell R.A. Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity. J. Clin. Invest. 1994, 94:2028-2035.
34. Ono A., Utsugi M., Masubuchi K., Ishizuka T., Kawata T., Shimizu Y., Hisada T., Hamuro J., Mori M., Dobashi K. Glutathione redox regulates TGF-β-induced fibrogenic effects through Smad3 activation. FEBS Lett. 2009, 583:357-362.
35. Leivonen S.K., Hakkinen L., Liu D., Kahari V.M. Smad3 and extracellular signal-regulated kinase 1/2 coordinately mediate transforming growth factor-beta-induced expression of connective tissue growth factor in human fibroblasts. J. Invest. Dermatol. 2005, 124:1162-1169.
36. Mogi C., Tobo M., Tomura H., Murata N., He X.D., Sato K., Kimura T., Ishizuka T., Sasaki T., Sato T., Kihara Y., Ishii S., Harada A., Okajima F. Involvement of proton-sensing TDAG8 in extracellular acidification-induced inhibition of proinflammatory cytokine production in peritoneal macrophages. J. Immunol. 2009, 182:3243-3251.