Acid sensing ion channel 1 in lateral hypothalamus contributes to breathing control

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Song, Nana ^a   Zhang, Guihong ^a   Geng, Wenye ^a   Liu, Zibing ^a   Jin, Weizhong ^a   Li, Li ^a   Cao, Yinxiang ^a   Zhu, Danian ^a   Yu, Jerry ^a,b   Shen, Linlin ^a  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1; AMILORIDE; OREXIN A; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; IMMUNOFLUORESCENCE TEST; LATERAL HYPOTHALAMUS; MALE; NONHUMAN; PEAK INSPIRATORY FLOW; PH MEASUREMENT; PHARMACOLOGICAL BLOCKING; PHRENIC NERVE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RESPIRATION CONTROL; RESPIRATORY DRIVE; SENSITIVITY ANALYSIS;

ACID SENSING ION CHANNEL BLOCKERS; ACID SENSING ION CHANNELS; ACIDOSIS; AMILORIDE; ANIMALS; ARTERIAL PRESSURE; BODY WEIGHT; GENE EXPRESSION; HEART RATE; HYDROGEN-ION CONCENTRATION; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEURONS; NEUROPEPTIDES; PHRENIC NERVE; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION; RESPIRATORY CENTER; RESPIRATORY RATE;

RATTUS;

EID: 84863655028     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039982     Document Type: Article

References (54)

1. Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M, (1997) A proton-gated cation channel involved in acid-sensing. Nature 386: 173-177.
2. Xiong ZG, Pignataro G, Li M, Chang SY, Simon RP, (2008) Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr Opin Pharmacol 8: 25-32.
3. 2+ ions. Brain Res 900: 277-281.
4. Chen CC, England S, Akopian AN, Wood JN, (1998) A sensory neuron-specific, proton-gated ion channel. Proc Natl Acad Sci U S A 95: 10240-10245.
5. Lingueglia E, de WeilleJR, Bassilana F, Heurteaux C, Sakai H, et al. (1997) A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. J Biol Chem 272: 29778-29783.
6. Bassilana F, Champigny G, Waldmann R, de WeilleJR, Heurteaux C, et al. (1997) The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties. J Biol Chem 272: 28819-28822.
7. 3+. J Biol Chem 275: 28519-28525.
8. Donier E, Rugiero F, Jacob C, Wood JN, (2008) Regulation of ASIC activity by ASIC4-new insights into ASIC channel function revealed by a yeast two-hybrid assay. Eur J Neurosci 28: 74-86.
9. Ugawa S, Yamamoto T, Ueda T, Ishida Y, Inagaki A, et al. (2003) Amiloride-insensitive currents of the acid-sensing ion channel-2a (ASIC2a)/ASIC2b heteromeric sour-taste receptor channel. J Neurosci 23: 3616-3622.
10. Hildebrand MS, de Silva MG, Klockars T, Rose E, Price M, et al. (2004) Characterisation of DRASIC in the mouse inner ear. Hear Res 190: 149-160.
11. Peng BG, Ahmad S, Chen S, Chen P, Price MP, et al. (2004) Acid-sensing ion channel 2 contributes a major component to acid-evoked excitatory responses in spiral ganglion neurons and plays a role in noise susceptibility of mice. J Neurosci 24: 10167-10175.
12. Benson CJ, Eckert SP, McCleskey EW, (1999) Acid-evoked currents in cardiac sensory neurons: A possible mediator of myocardial ischemic sensation. Circ Res 84: 921-928.
13. Price MP, Lewin GR, McIlwrath SL, Cheng C, Xie J, et al. (2000) The mammalian sodium channel BNC1 is required for normal touch sensation. Nature 407: 1007-1011.
14. Price MP, McIlwrath SL, Xie J, Cheng C, Qiao J, et al. (2001) The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice. Neuron 32: 1071-1083.
15. Garcia-Anoveros J, Samad TA, Zuvela-Jelaska L, Woolf CJ, Corey DP, (2001) Transport and localization of the DEG/ENaC ion channel BNaC1alpha to peripheral mechanosensory terminals of dorsal root ganglia neurons. J Neurosci 21: 2678-2686.
16. Lingueglia E, (2007) Acid-sensing ion channels in sensory perception. J Biol Chem 282: 17325-17329.
17. Wemmie JA, Askwith CC, Lamani E, Cassell MD, Freeman JH Jr, et al. (2003) Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. J Neurosci 23: 5496-5502.
18. Alvarez de la Rosa D, Krueger SR, Kolar A, Shao D, Fitzsimonds RM, et al. (2003) Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system. J Physiol 546: 77-87.
19. Redgate ES, Gellhorn E, (1958) Respiratory activity and the hypothalamus. Am J Physiol 193: 189-194.
20. Liu ZB, Song NN, Geng WY, Jin WZ, Li L, et al. (2010) Orexin-A and respiration in a rat model of smoke-induced chronic obstructive pulmonary disease. Clinical and Experimental Pharmacology and Physiology 37: 963-968.
21. Saper CB, Chou TC, Scammell TE, (2001) The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci 24: 726-731.
22. 2+. Proc Natl Acad Sci U S A 104: 10685-10690.
23. Waldmann R, Bassilana F, de Weille J, Champigny G, Heurteaux C, et al. (1997) Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neurons. J Biol Chem 272: 20975-20978.
24. Garcia-Añoveros J DB, Neville-Golden J, Hyman BT, Corey DP, (1997) BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc Natl Acad Sci U S A 94: 1459-1464.
25. Chu XP, Miesch J, Johnson M, Root L, Zhu XM, et al. (2002) Proton-gated channels in PC12 cells. J Neurophysiol 87: 2555-2561.
26. Benson CJ, Xie J, Wemmie JA, Price MP, Henss JM, et al. (2002) Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons. Proc Natl Acad Sci U S A 99: 2338-2343.
27. Askwith CC, Wemmie JA, Price MP, Rokhlina T, Welsh MJ, (2004) Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons. J Biol Chem 279: 18296-18305.
28. Meng QY, Wang W, Chen XN, Xu TL, Zhou JN, (2009) Distribution of acid-sensing ion channel 3 in the rat hypothalamus. Neuroscience 159: 1126-1134.
29. Cao XL, Chen Q, Zhou H, Tang YH, Xu JG, et al. (2009) Expression of ASIC 1b, 2a and 3 in neurons of nucleus of trapezoid body and lateral paragigantocellular nucleus and effects of intermittent hypoxia on their expression. Journal of Sichuan University (Medical Science Edition) 40: 662-666.
30. 2+ in cultured hypothalamic neurons of the rat. Neuroscience 145: 631-641.
31. Zha XM, Wemmie JA, Green SH, Welsh MJ, (2006) Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines. Proc Natl Acad Sci U S A 103: 16556-16561.
32. Yermolaieva O, Leonard AS, Schnizler MK, Abboud FM, Welsh MJ, (2004) Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a. Proc Natl Acad Sci U S A 101: 6752-6757.
33. Krishtal O, (2003) The ASICs: signaling molecules? Modulators? Trends Neurosci 26: 477-483.
34. Yuan FL, Chen FH, Lu WG, Li X, Wu FR, et al. (2010) Acid-sensing ion channel 1a mediates acid-induced increases in intracellular calcium in rat articular chondrocytes. Molecular and Cellular Biochemistry 340: 153-159.
35. Dong X, Ko KH, Chow J, Tuo B, Barrett KE, et al. (2011) Expression of acid-sensing ion channels in intestinal epithelial cells and their role in the regulation of duodenal mucosal bicarbonate secretion. Acta Physiologica 201: 97-107.
36. Tanaka M, McAllen RM, (2008) Functional topography of the dorsomedial hypothalamus. Am J Physiol Regul Integr Comp Physiol 294: R477-486.
37. Berquin P, Bodineau L, Gros F, Larnicol N, (2000) Brainstem and hypothalamic areas involved in respiratory chemoreflexes: a Fos study in adult rats. Brain Res 857: 30-40.
38. 2+-induced c-Fos expression in hypothalamic vasopressin containing neurons. Respir Physiol 129: 289-296.
39. 2+ activates orexin-containing neurons in mice. Respiratory Physiology & Neurobiology 166: 184-186.
40. Kayaba Y, Nakamura A, Kasuya Y, Ohuchi T, Yanagisawa M, et al. (2003) Attenuated defense response and low basal blood pressure in orexin knockout mice. Am J Physiol Regul Integr Comp Physiol 285: R581-593.
41. Nakamura A, Zhang W, Yanagisawa M, Fukuda Y, Kuwaki T, (2007) Vigilance state-dependent attenuation of hypercapnic chemoreflex and exaggerated sleep apnea in orexin knockout mice. J Appl Physiol 102: 241-248.
42. Fung SJ, Yamuy J, Sampogna S, Morales FR, Chase MH, (2001) Hypocretin (orexin) input to trigeminal and hypoglossal motoneurons in the cat: a double-labeling immunohistochemical study. Brain Res 903: 257-262.
43. Krout KE, Mettenleiter TC, Karpitskiy V, Nguyen XV, Loewy AD, (2005) CNS neurons with links to both mood-related cortex and sympathetic nervous system. Brain Res 1050: 199-202.
44. Young JK, Wu M, Manaye KF, Kc P, Allard JS, et al. (2005) Orexin stimulates breathing via medullary and spinal pathways. J Appl Physiol 98: 1387-1395.
45. Kuwaki T, Li A, Nattie E, (2010) State-dependent central chemoreception: A role of orexin. Respiratory Physiology & Neurobiology 173: 223-229.
46. Dias MB, Li A, Nattie E, (2010) The orexin receptor 1 (OX1R) in the rostral medullary raphe contributes to the hypercapnic chemoreflex in wakefulness, during the active period of the diurnal cycle. Respiratory Physiology & Neurobiology 170: 96-102.
47. Li A, Nattie E, (2010) Antagonism of rat orexin receptors by almorexant attenuates central chemoreception in wakefulness in the active period of the diurnal cycle. The Journal of Physiology 588: 2935-2944.
48. Dias MB, Li A, Nattie EE, (2009) Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness. The Journal of Physiology 587: 2059-2067.
49. Johnson PL, Truitt W, Fitz SD, Minick PE, Dietrich A, et al. (2010) A key role for orexin in panic anxiety. Nat Med 16: 111-115.
50. Han F, (2011) Narcolepsy, orexins and respiratory regulation. Sleep and Biological Rhythms 9: 44-51.
51. von der Goltz C, Koopmann A, Dinter C, Richter A, Grosshans M, et al. (2011) Involvement of orexin in the regulation of stress, depression and reward in alcohol dependence. Hormones and Behavior 60: 644-650.
52. Guyenet PG, Mulkey DK, Stornetta RL, Bayliss DA, (2005) Regulation of ventral surface chemoreceptors by the central respiratory pattern generator. J Neurosci 25: 8938-8947.
53. Mulkey DK, Stornetta RL, Weston MC, Simmons JR, Parker A, et al. (2004) Respiratory control by ventral surface chemoreceptor neurons in rats. Nat Neurosci 7: 1360-1369.
54. Paxinos G, Watson C, (2006) The Rat Brain in Stereotaxic Coordinates. Academic Press San Diego, CA, USA.