Calcineurin inhibitors promote chondrogenic marker expression of dedifferentiated human adult chondrocytes via stimulation of endogenous TGFβ1 production

Tissue Engineering - Part A

Volumn 16, Issue 1, 2010, Pages 1-10

  Van Der Windt, Anna E ^a   Jahr, Holger ^a   Farrell, Eric ^a   Verhaar, Jan A N ^a   Weinans, Harrie ^a   Van Osch, Gerjo J V M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CARTILAGE; CELL CULTURE; ENZYME INHIBITION; GENE EXPRESSION; LIGAMENTS; REPAIR;

CALCINEURIN; CALCINEURIN INHIBITORS; CALCIUM INFLUX; CARTILAGE REPAIR; CELL-BASED; CHONDROCYTE REDIFFERENTIATION; CHONDROCYTES; CHONDROGENIC MARKERS; CHONDROGENIC PHENOTYPES; HUMAN ARTICULAR CHONDROCYTES; IN-VITRO; PROTEIN LEVEL; TRANSFORMING GROWTH FACTORS;

BODY FLUIDS;

CALCINEURIN; DIFFERENTIATION ANTIGEN; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY; TACROLIMUS; TRANSFORMING GROWTH FACTOR BETA1;

AGED; ARTICLE; ARTICULAR CARTILAGE; BIOSYNTHESIS; CARTILAGE CELL; CELL CULTURE; CELL DEDIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; HUMAN; MALE; METABOLISM; MIDDLE AGED;

AGED; ANTIBODIES, MONOCLONAL; ANTIGENS, DIFFERENTIATION; CALCINEURIN; CARTILAGE, ARTICULAR; CELL DEDIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; MIDDLE AGED; TACROLIMUS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77049090563     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0082     Document Type: Article

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