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Volumn 184, Issue 1, 2014, Pages 18-27

LDL receptor-related protein-1: A regulator of inflammation in atherosclerosis, cancer, and injury to the nervous system

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; HEAT SHOCK PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

EID: 84890389234     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.08.029     Document Type: Review
Times cited : (151)

References (100)
  • 1
    • 0001665337 scopus 로고
    • Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
    • J. Herz, U. Hamann, S. Rogne, O. Myklebost, H. Gausepohl, and K.K. Stanley Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor EMBO J 7 1988 4119 4127
    • (1988) EMBO J , vol.7 , pp. 4119-4127
    • Herz, J.1    Hamann, U.2    Rogne, S.3    Myklebost, O.4    Gausepohl, H.5    Stanley, K.K.6
  • 2
    • 0025369190 scopus 로고
    • Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment
    • J. Herz, R.C. Kowal, J.L. Goldstein, and M.S. Brown Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment EMBO J 9 1990 1769 1776
    • (1990) EMBO J , vol.9 , pp. 1769-1776
    • Herz, J.1    Kowal, R.C.2    Goldstein, J.L.3    Brown, M.S.4
  • 3
    • 0018856999 scopus 로고
    • Primary amines inhibit recycling of alpha 2M receptors in fibroblasts
    • F. Van Leuven, J.J. Cassiman, and H. Van Den Berghe Primary amines inhibit recycling of alpha 2M receptors in fibroblasts Cell 20 1980 37 43
    • (1980) Cell , vol.20 , pp. 37-43
    • Van Leuven, F.1    Cassiman, J.J.2    Van Den Berghe, H.3
  • 4
    • 0025652124 scopus 로고
    • Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver
    • J. Herz, R.C. Kowal, Y.K. Ho, M.S. Brown, and J.L. Goldstein Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver J Biol Chem 265 1990 21355 21362
    • (1990) J Biol Chem , vol.265 , pp. 21355-21362
    • Herz, J.1    Kowal, R.C.2    Ho, Y.K.3    Brown, M.S.4    Goldstein, J.L.5
  • 5
    • 28044434891 scopus 로고    scopus 로고
    • The low-density lipoprotein receptor-related protein-1 associates transiently with lipid rafts
    • L. Wu, and S.L. Gonias The low-density lipoprotein receptor-related protein-1 associates transiently with lipid rafts J Cell Biochem 96 2005 1021 1033
    • (2005) J Cell Biochem , vol.96 , pp. 1021-1033
    • Wu, L.1    Gonias, S.L.2
  • 6
    • 0018927306 scopus 로고
    • The receptosome: An intermediate organelle of receptor mediated endocytosis in cultured fibroblasts
    • M.C. Willingham, and I. Pastan The receptosome: an intermediate organelle of receptor mediated endocytosis in cultured fibroblasts Cell 21 1980 67 77
    • (1980) Cell , vol.21 , pp. 67-77
    • Willingham, M.C.1    Pastan, I.2
  • 7
    • 8744266243 scopus 로고    scopus 로고
    • Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier
    • W. Pan, A.J. Kastin, T.C. Zankel, P. van Kerkhof, T. Terasaki, and G. Bu Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier J Cell Sci 117 2004 5071 5078
    • (2004) J Cell Sci , vol.117 , pp. 5071-5078
    • Pan, W.1    Kastin, A.J.2    Zankel, T.C.3    Van Kerkhof, P.4    Terasaki, T.5    Bu, G.6
  • 10
    • 0033615548 scopus 로고    scopus 로고
    • The second and fourth cluster of class A cysteine-rich repeats of the low density lipoprotein receptor-related protein share ligand-binding properties
    • J.G. Neels, B.M. van Den Berg, A. Lookene, G. Olivecrona, H. Pannekoek, and A.J. van Zonneveld The second and fourth cluster of class A cysteine-rich repeats of the low density lipoprotein receptor-related protein share ligand-binding properties J Biol Chem 274 1999 31305 31311
    • (1999) J Biol Chem , vol.274 , pp. 31305-31311
    • Neels, J.G.1    Van Den Berg, B.M.2    Lookene, A.3    Olivecrona, G.4    Pannekoek, H.5    Van Zonneveld, A.J.6
  • 11
    • 0034595799 scopus 로고    scopus 로고
    • The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein
    • Y. Li, M.P. Marzolo, P. van Kerkhof, G.J. Strous, and G. Bu The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein J Biol Chem 275 2000 17187 17194
    • (2000) J Biol Chem , vol.275 , pp. 17187-17194
    • Li, Y.1    Marzolo, M.P.2    Van Kerkhof, P.3    Strous, G.J.4    Bu, G.5
  • 12
    • 0032509346 scopus 로고    scopus 로고
    • Interaction of cytosolic adaptor proteins with neuronal apolipoprotein e receptors and the amyloid precursor protein
    • M. Trommsdorff, J.P. Borg, B. Margolis, and J. Herz Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein J Biol Chem 273 1998 33556 33560
    • (1998) J Biol Chem , vol.273 , pp. 33556-33560
    • Trommsdorff, M.1    Borg, J.P.2    Margolis, B.3    Herz, J.4
  • 13
    • 18544378303 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP): Evidence for integrated co-receptor function between LRP and the PDGF
    • E. Loukinova, S. Ranganathan, S. Kuznetsov, N. Gorlatova, M.M. Migliorini, D. Loukinov, P.G. Ulery, I. Mikhailenko, D.A. Lawrence, and D.K. Strickland Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP): evidence for integrated co-receptor function between LRP and the PDGF J Biol Chem 277 2002 15499 15506
    • (2002) J Biol Chem , vol.277 , pp. 15499-15506
    • Loukinova, E.1    Ranganathan, S.2    Kuznetsov, S.3    Gorlatova, N.4    Migliorini, M.M.5    Loukinov, D.6    Ulery, P.G.7    Mikhailenko, I.8    Lawrence, D.A.9    Strickland, D.K.10
  • 14
    • 0040177065 scopus 로고
    • Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins
    • R.C. Kowal, J. Herz, J.L. Goldstein, V. Esser, and M.S. Brown Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins Proc Natl Acad Sci U S A 86 1989 5810 5814
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 5810-5814
    • Kowal, R.C.1    Herz, J.2    Goldstein, J.L.3    Esser, V.4    Brown, M.S.5
  • 15
    • 0025080835 scopus 로고
    • Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor
    • D.K. Strickland, J.D. Ashcom, S. Williams, W.H. Burgess, M. Migliorini, and W.S. Argraves Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor J Biol Chem 265 1990 17401 17404
    • (1990) J Biol Chem , vol.265 , pp. 17401-17404
    • Strickland, D.K.1    Ashcom, J.D.2    Williams, S.3    Burgess, W.H.4    Migliorini, M.5    Argraves, W.S.6
  • 16
    • 19444365227 scopus 로고    scopus 로고
    • Mutation of lysine 1370 in full-length human alpha2-macroglobulin blocks binding to the low density lipoprotein receptor-related protein-1
    • S. Arandjelovic, B.D. Hall, and S.L. Gonias Mutation of lysine 1370 in full-length human alpha2-macroglobulin blocks binding to the low density lipoprotein receptor-related protein-1 Arch Biochem Biophys 438 2005 29 35
    • (2005) Arch Biochem Biophys , vol.438 , pp. 29-35
    • Arandjelovic, S.1    Hall, B.D.2    Gonias, S.L.3
  • 17
    • 84858321170 scopus 로고    scopus 로고
    • A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein)
    • P.G. Gettins, and K. Dolmer A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein) Biochem J 443 2012 65 73
    • (2012) Biochem J , vol.443 , pp. 65-73
    • Gettins, P.G.1    Dolmer, K.2
  • 19
    • 84875616437 scopus 로고    scopus 로고
    • LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin
    • T.L. Stiles, T.L. Dickendesher, A. Gaultier, A. Fernandez-Castaneda, E. Mantuano, R.J. Giger, and S.L. Gonias LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin J Cell Sci 126 2013 209 220
    • (2013) J Cell Sci , vol.126 , pp. 209-220
    • Stiles, T.L.1    Dickendesher, T.L.2    Gaultier, A.3    Fernandez-Castaneda, A.4    Mantuano, E.5    Giger, R.J.6    Gonias, S.L.7
  • 20
    • 0035903289 scopus 로고    scopus 로고
    • C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells
    • C. Ogden, A. deCathelineau, P. Hoffmann, D. Bratton, B. Ghebrehiwet, V. Fadok, and P. Henson C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells J Exp Med 194 2001 781 795
    • (2001) J Exp Med , vol.194 , pp. 781-795
    • Ogden, C.1    Decathelineau, A.2    Hoffmann, P.3    Bratton, D.4    Ghebrehiwet, B.5    Fadok, V.6    Henson, P.7
  • 21
    • 0141918823 scopus 로고    scopus 로고
    • By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation
    • S.J. Gardai, Y.Q. Xiao, M. Dickinson, J.A. Nick, D.R. Voelker, K.E. Greene, and P.M. Henson By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation Cell 115 2003 13 23
    • (2003) Cell , vol.115 , pp. 13-23
    • Gardai, S.J.1    Xiao, Y.Q.2    Dickinson, M.3    Nick, J.A.4    Voelker, D.R.5    Greene, K.E.6    Henson, P.M.7
  • 22
    • 84874088008 scopus 로고    scopus 로고
    • Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris
    • A. Fernandez-Castaneda, S. Arandjelovic, T.L. Stiles, R.K. Schlobach, K.A. Mowen, S.L. Gonias, and A. Gaultier Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris J Biol Chem 288 2013 4538 4548
    • (2013) J Biol Chem , vol.288 , pp. 4538-4548
    • Fernandez-Castaneda, A.1    Arandjelovic, S.2    Stiles, T.L.3    Schlobach, R.K.4    Mowen, K.A.5    Gonias, S.L.6    Gaultier, A.7
  • 23
    • 2342584674 scopus 로고    scopus 로고
    • Clearance of apoptotic cells: Getting rid of the corpses
    • K. Lauber, S.G. Blumenthal, M. Waibel, and S. Wesselborg Clearance of apoptotic cells: getting rid of the corpses Mol Cell 14 2004 277 287
    • (2004) Mol Cell , vol.14 , pp. 277-287
    • Lauber, K.1    Blumenthal, S.G.2    Waibel, M.3    Wesselborg, S.4
  • 24
    • 3042664089 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein: Regulation of the plasma membrane proteome
    • S.L. Gonias, L. Wu, and A.M. Salicioni Low density lipoprotein receptor-related protein: regulation of the plasma membrane proteome Thromb Haemost 91 2004 1056 1064
    • (2004) Thromb Haemost , vol.91 , pp. 1056-1064
    • Gonias, S.L.1    Wu, L.2    Salicioni, A.M.3
  • 25
    • 78649807482 scopus 로고    scopus 로고
    • LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome
    • A. Gaultier, G. Simon, S. Niessen, M. Dix, S. Takimoto, B. Cravatt 3rd, and S. Gonias LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome J Proteome Res 9 2010 6689 6695
    • (2010) J Proteome Res , vol.9 , pp. 6689-6695
    • Gaultier, A.1    Simon, G.2    Niessen, S.3    Dix, M.4    Takimoto, S.5    Cravatt III, B.6    Gonias, S.7
  • 26
    • 0034629292 scopus 로고    scopus 로고
    • Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP): Evidence that LRP contributes to the pathogenesis of Alzheimer's disease
    • P. Ulery, J. Beers, I. Mikhailenko, R. Tanzi, G. Rebeck, B. Hyman, and D. Strickland Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP): evidence that LRP contributes to the pathogenesis of Alzheimer's disease J Biol Chem 275 2000 7410 7415
    • (2000) J Biol Chem , vol.275 , pp. 7410-7415
    • Ulery, P.1    Beers, J.2    Mikhailenko, I.3    Tanzi, R.4    Rebeck, G.5    Hyman, B.6    Strickland, D.7
  • 27
    • 2442498577 scopus 로고    scopus 로고
    • FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein
    • C.U. Pietrzik, I.S. Yoon, S. Jaeger, T. Busse, S. Weggen, and E. Koo FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein J Neurosci 24 2004 4259 4265
    • (2004) J Neurosci , vol.24 , pp. 4259-4265
    • Pietrzik, C.U.1    Yoon, I.S.2    Jaeger, S.3    Busse, T.4    Weggen, S.5    Koo, E.6
  • 29
    • 80051682259 scopus 로고    scopus 로고
    • Regulation of the urokinase receptor (uPAR) by LDL receptor-related protein-1 (LRP1)
    • S.L. Gonias, A. Gaultier, and M. Jo Regulation of the urokinase receptor (uPAR) by LDL receptor-related protein-1 (LRP1) Curr Pharm Des 17 2011 1962 1969
    • (2011) Curr Pharm des , vol.17 , pp. 1962-1969
    • Gonias, S.L.1    Gaultier, A.2    Jo, M.3
  • 30
    • 0028355715 scopus 로고
    • The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor
    • I. Warshawsky, G.J. Broze Jr., and A.L. Schwartz The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor Proc Natl Acad Sci U S A 91 1994 6664 6668
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 6664-6668
    • Warshawsky, I.1    Broze, Jr.G.J.2    Schwartz, A.L.3
  • 31
    • 0025786502 scopus 로고
    • 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor
    • J. Herz, J.L. Goldstein, D.K. Strickland, Y.K. Ho, and M.S. Brown 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor J Biol Chem 266 1991 21232 21238
    • (1991) J Biol Chem , vol.266 , pp. 21232-21238
    • Herz, J.1    Goldstein, J.L.2    Strickland, D.K.3    Ho, Y.K.4    Brown, M.S.5
  • 32
    • 0035070198 scopus 로고    scopus 로고
    • CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
    • S. Basu, R.J. Binder, T. Ramalingam, and P.K. Srivastava CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin Immunity 14 2001 303 313
    • (2001) Immunity , vol.14 , pp. 303-313
    • Basu, S.1    Binder, R.J.2    Ramalingam, T.3    Srivastava, P.K.4
  • 33
    • 1942501656 scopus 로고    scopus 로고
    • Essential role of CD91 in re-presentation of gp96-chaperoned peptides
    • R.J. Binder, and P.K. Srivastava Essential role of CD91 in re-presentation of gp96-chaperoned peptides Proc Natl Acad Sci U S A 101 2004 6128 6133
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6128-6133
    • Binder, R.J.1    Srivastava, P.K.2
  • 34
    • 0027499466 scopus 로고
    • Receptor-mediated antigen delivery into macrophages: Complexing antigen to alpha 2-macroglobulin enhances presentation to T cells
    • C.T. Chu, and S.V. Pizzo Receptor-mediated antigen delivery into macrophages: complexing antigen to alpha 2-macroglobulin enhances presentation to T cells J Immunol 150 1993 48 58
    • (1993) J Immunol , vol.150 , pp. 48-58
    • Chu, C.T.1    Pizzo, S.V.2
  • 35
    • 84868601059 scopus 로고    scopus 로고
    • LRP1 mediates Hedgehog-induced endocytosis of the GPC3-Hedgehog complex
    • M.I. Capurro, W. Shi, and J. Filmus LRP1 mediates Hedgehog-induced endocytosis of the GPC3-Hedgehog complex J Cell Sci 125 2012 3380 3389
    • (2012) J Cell Sci , vol.125 , pp. 3380-3389
    • Capurro, M.I.1    Shi, W.2    Filmus, J.3
  • 37
    • 0037432766 scopus 로고    scopus 로고
    • LRP: Role in vascular wall integrity and protection from atherosclerosis
    • P. Boucher, M. Gotthardt, W.P. Li, R.G. Anderson, and J. Herz LRP: role in vascular wall integrity and protection from atherosclerosis Science 300 2003 329 332
    • (2003) Science , vol.300 , pp. 329-332
    • Boucher, P.1    Gotthardt, M.2    Li, W.P.3    Anderson, R.G.4    Herz, J.5
  • 38
    • 23044469458 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP): Evidence for co-receptor function
    • C.S. Newton, E. Loukinova, I. Mikhailenko, S. Ranganathan, Y. Gao, C. Haudenschild, and D.K. Strickland Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP): evidence for co-receptor function J Biol Chem 280 2005 27872 27878
    • (2005) J Biol Chem , vol.280 , pp. 27872-27878
    • Newton, C.S.1    Loukinova, E.2    Mikhailenko, I.3    Ranganathan, S.4    Gao, Y.5    Haudenschild, C.6    Strickland, D.K.7
  • 39
    • 77952002497 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein 1 (LRP1) forms a signaling complex with platelet-derived growth factor receptor-beta in endosomes and regulates activation of the MAPK pathway
    • S.C. Muratoglu, I. Mikhailenko, C. Newton, M. Migliorini, and D.K. Strickland Low density lipoprotein receptor-related protein 1 (LRP1) forms a signaling complex with platelet-derived growth factor receptor-beta in endosomes and regulates activation of the MAPK pathway J Biol Chem 285 2010 14308 14317
    • (2010) J Biol Chem , vol.285 , pp. 14308-14317
    • Muratoglu, S.C.1    Mikhailenko, I.2    Newton, C.3    Migliorini, M.4    Strickland, D.K.5
  • 40
    • 4544297239 scopus 로고    scopus 로고
    • Apolipoprotein e receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons
    • Z. Qiu, B.T. Hyman, and G.W. Rebeck Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons J Biol Chem 279 2004 34948 34956
    • (2004) J Biol Chem , vol.279 , pp. 34948-34956
    • Qiu, Z.1    Hyman, B.T.2    Rebeck, G.W.3
  • 41
    • 33644869414 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression
    • K. Hu, J. Yang, S. Tanaka, S.L. Gonias, W.M. Mars, and Y. Liu Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression J Biol Chem 281 2006 2120 2127
    • (2006) J Biol Chem , vol.281 , pp. 2120-2127
    • Hu, K.1    Yang, J.2    Tanaka, S.3    Gonias, S.L.4    Mars, W.M.5    Liu, Y.6
  • 42
    • 33847240080 scopus 로고    scopus 로고
    • Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1
    • H. Hayashi, R. Campenot, D. Vance, and J. Vance Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1 J Neurosci 27 2007 1933 1941
    • (2007) J Neurosci , vol.27 , pp. 1933-1941
    • Hayashi, H.1    Campenot, R.2    Vance, D.3    Vance, J.4
  • 43
    • 50649110085 scopus 로고    scopus 로고
    • Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling
    • E. Mantuano, G. Mukandala, X. Li, W.M. Campana, and S.L. Gonias Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling J Biol Chem 283 2008 19904 19911
    • (2008) J Biol Chem , vol.283 , pp. 19904-19911
    • Mantuano, E.1    Mukandala, G.2    Li, X.3    Campana, W.M.4    Gonias, S.L.5
  • 45
    • 58149266689 scopus 로고    scopus 로고
    • The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein
    • E. Mantuano, G. Inoue, X. Li, K. Takahashi, A. Gaultier, S.L. Gonias, and W.M. Campana The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein J Neurosci 28 2008 11571 11582
    • (2008) J Neurosci , vol.28 , pp. 11571-11582
    • Mantuano, E.1    Inoue, G.2    Li, X.3    Takahashi, K.4    Gaultier, A.5    Gonias, S.L.6    Campana, W.M.7
  • 46
    • 0034633703 scopus 로고    scopus 로고
    • The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors
    • B. Bacskai, M. Xia, D. Strickland, G. Rebeck, and B. Hyman The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors Proc Natl Acad Sci U S A 97 2000 11551 11556
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 11551-11556
    • Bacskai, B.1    Xia, M.2    Strickland, D.3    Rebeck, G.4    Hyman, B.5
  • 47
    • 70349327570 scopus 로고    scopus 로고
    • Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway
    • Y. Shi, E. Mantuano, G. Inoue, W. Campana, and S. Gonias Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway Sci Signal 2 2009 ra18
    • (2009) Sci Signal , vol.2 , pp. 18
    • Shi, Y.1    Mantuano, E.2    Inoue, G.3    Campana, W.4    Gonias, S.5
  • 48
    • 0037166319 scopus 로고    scopus 로고
    • Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain
    • P. May, Y.K. Reddy, and J. Herz Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain J Biol Chem 277 2002 18736 18743
    • (2002) J Biol Chem , vol.277 , pp. 18736-18743
    • May, P.1    Reddy, Y.K.2    Herz, J.3
  • 49
    • 58749110564 scopus 로고    scopus 로고
    • Gamma-secretase limits the inflammatory response through the processing of LRP1
    • K. Zurhove, C. Nakajima, J. Herz, H.H. Bock, and P. May Gamma-secretase limits the inflammatory response through the processing of LRP1 Sci Signal 1 2008 ra15
    • (2008) Sci Signal , vol.1 , pp. 15
    • Zurhove, K.1    Nakajima, C.2    Herz, J.3    Bock, H.H.4    May, P.5
  • 51
    • 77957866595 scopus 로고    scopus 로고
    • Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages
    • M. Gorovoy, A. Gaultier, W.M. Campana, G.S. Firestein, and S.L. Gonias Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages J Leukoc Biol 88 2010 769 778
    • (2010) J Leukoc Biol , vol.88 , pp. 769-778
    • Gorovoy, M.1    Gaultier, A.2    Campana, W.M.3    Firestein, G.S.4    Gonias, S.L.5
  • 52
    • 0026439778 scopus 로고
    • LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation
    • J. Herz, D.E. Couthier, and R.E. Hammer LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation Cell 71 1992 411 421
    • (1992) Cell , vol.71 , pp. 411-421
    • Herz, J.1    Couthier, D.E.2    Hammer, R.E.3
  • 53
    • 0026673511 scopus 로고
    • Signal transduction in atherosclerosis: Integration of cytokines and the eicosanoid network
    • D.P. Hajjar, and K.B. Pomerantz Signal transduction in atherosclerosis: integration of cytokines and the eicosanoid network FASEB J 6 1992 2933 2941
    • (1992) FASEB J , vol.6 , pp. 2933-2941
    • Hajjar, D.P.1    Pomerantz, K.B.2
  • 54
    • 33845358396 scopus 로고    scopus 로고
    • Intertwining of thrombosis and inflammation in atherosclerosis
    • K. Croce, and P. Libby Intertwining of thrombosis and inflammation in atherosclerosis Curr Opin Hematol 14 2007 55 61
    • (2007) Curr Opin Hematol , vol.14 , pp. 55-61
    • Croce, K.1    Libby, P.2
  • 56
    • 0027296736 scopus 로고
    • Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response
    • G.A. Stouffer, J. LaMarre, S.L. Gonias, and G.K. Owens Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response J Biol Chem 268 1993 18340 18344
    • (1993) J Biol Chem , vol.268 , pp. 18340-18344
    • Stouffer, G.A.1    Lamarre, J.2    Gonias, S.L.3    Owens, G.K.4
  • 58
    • 33947715605 scopus 로고    scopus 로고
    • Deletion of macrophage LDL receptor-related protein increases atherogenesis in the mouse
    • C. Overton, P. Yancey, A. Major, M. Linton, and S. Fazio Deletion of macrophage LDL receptor-related protein increases atherogenesis in the mouse Circ Res 100 2007 670 677
    • (2007) Circ Res , vol.100 , pp. 670-677
    • Overton, C.1    Yancey, P.2    Major, A.3    Linton, M.4    Fazio, S.5
  • 59
    • 79961027891 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: Evidence that the effects are not apolipoprotein e dependent
    • P.G. Yancey, Y. Ding, D. Fan, J.L. Blakemore, Y. Zhang, L. Ding, J. Zhang, M.F. Linton, and S. Fazio Low-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: evidence that the effects are not apolipoprotein E dependent Circulation 124 2011 454 464
    • (2011) Circulation , vol.124 , pp. 454-464
    • Yancey, P.G.1    Ding, Y.2    Fan, D.3    Blakemore, J.L.4    Zhang, Y.5    Ding, L.6    Zhang, J.7    Linton, M.F.8    Fazio, S.9
  • 61
    • 45949089484 scopus 로고    scopus 로고
    • Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor
    • A. Gaultier, S. Arandjelovic, S. Niessen, C.D. Overton, M.F. Linton, S. Fazio, W.M. Campana, B.F. Cravatt 3rd, and S.L. Gonias Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor Blood 111 2008 5316 5325
    • (2008) Blood , vol.111 , pp. 5316-5325
    • Gaultier, A.1    Arandjelovic, S.2    Niessen, S.3    Overton, C.D.4    Linton, M.F.5    Fazio, S.6    Campana, W.M.7    Cravatt III, B.F.8    Gonias, S.L.9
  • 63
    • 0025223182 scopus 로고
    • Colony-stimulating factor-1 modulates alpha 2-macroglobulin receptor expression in murine bone marrow macrophages
    • I.M. Hussaini, K. Srikumar, P.J. Quesenberry, and S.L. Gonias Colony-stimulating factor-1 modulates alpha 2-macroglobulin receptor expression in murine bone marrow macrophages J Biol Chem 265 1990 19441 19446
    • (1990) J Biol Chem , vol.265 , pp. 19441-19446
    • Hussaini, I.M.1    Srikumar, K.2    Quesenberry, P.J.3    Gonias, S.L.4
  • 64
    • 0027502159 scopus 로고
    • Regulation of macrophage alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein by lipopolysaccharide and interferon-gamma
    • J. LaMarre, B.B. Wolf, E.L. Kittler, P.J. Quesenberry, and S.L. Gonias Regulation of macrophage alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein by lipopolysaccharide and interferon-gamma J Clin Invest 91 1993 1219 1224
    • (1993) J Clin Invest , vol.91 , pp. 1219-1224
    • Lamarre, J.1    Wolf, B.B.2    Kittler, E.L.3    Quesenberry, P.J.4    Gonias, S.L.5
  • 65
    • 62649120101 scopus 로고    scopus 로고
    • Insulin induces the low density lipoprotein receptor-related protein 1 (LRP1) degradation by the proteasomal system in J774 macrophage-derived cells
    • D.G. Ceschin, M.C. Sanchez, and G.A. Chiabrando Insulin induces the low density lipoprotein receptor-related protein 1 (LRP1) degradation by the proteasomal system in J774 macrophage-derived cells J Cell Biochem 106 2009 372 380
    • (2009) J Cell Biochem , vol.106 , pp. 372-380
    • Ceschin, D.G.1    Sanchez, M.C.2    Chiabrando, G.A.3
  • 66
    • 84856220918 scopus 로고    scopus 로고
    • Macrophage expression of LRP1, a receptor for apoptotic cells and unopsonized erythrocytes, can be regulated by glucocorticoids
    • A. Nilsson, L. Vesterlund, and P.A. Oldenborg Macrophage expression of LRP1, a receptor for apoptotic cells and unopsonized erythrocytes, can be regulated by glucocorticoids Biochem Biophys Res Commun 417 2012 1304 1309
    • (2012) Biochem Biophys Res Commun , vol.417 , pp. 1304-1309
    • Nilsson, A.1    Vesterlund, L.2    Oldenborg, P.A.3
  • 68
    • 0028284556 scopus 로고
    • Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist
    • T.E. Willnow, Z. Sheng, S. Ishibashi, and J. Herz Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist Science 264 1994 1471 1474
    • (1994) Science , vol.264 , pp. 1471-1474
    • Willnow, T.E.1    Sheng, Z.2    Ishibashi, S.3    Herz, J.4
  • 70
    • 0018656991 scopus 로고
    • Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines
    • F. Van Leuven, J.J. Cassiman, and H. Van Den Berghe Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines J Biol Chem 254 1979 5155 5160
    • (1979) J Biol Chem , vol.254 , pp. 5155-5160
    • Van Leuven, F.1    Cassiman, J.J.2    Van Den Berghe, H.3
  • 72
    • 0030614317 scopus 로고    scopus 로고
    • Expression of alpha2-macroglobulin receptor/low density lipoprotein receptor-related protein on surfaces of tumour cells: A study using flow cytometry
    • Y. Li, N. Wood, P.G. Parsons, D. Yellowlees, and P.K. Donnelly Expression of alpha2-macroglobulin receptor/low density lipoprotein receptor-related protein on surfaces of tumour cells: a study using flow cytometry Cancer Lett 111 1997 199 205
    • (1997) Cancer Lett , vol.111 , pp. 199-205
    • Li, Y.1    Wood, N.2    Parsons, P.G.3    Yellowlees, D.4    Donnelly, P.K.5
  • 73
    • 35448935962 scopus 로고    scopus 로고
    • The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development
    • V. Montel, A. Gaultier, R.D. Lester, W.M. Campana, and S.L. Gonias The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development Cancer Res 67 2007 9817 9824
    • (2007) Cancer Res , vol.67 , pp. 9817-9824
    • Montel, V.1    Gaultier, A.2    Lester, R.D.3    Campana, W.M.4    Gonias, S.L.5
  • 74
    • 0029869167 scopus 로고    scopus 로고
    • In situ hybridization studies of alpha 2-macroglobulin receptor and receptor-associated protein in human prostate carcinoma
    • T. McGarvey, M.M. Hussain, and M.E. Stearns In situ hybridization studies of alpha 2-macroglobulin receptor and receptor-associated protein in human prostate carcinoma Prostate 28 1996 311 317
    • (1996) Prostate , vol.28 , pp. 311-317
    • McGarvey, T.1    Hussain, M.M.2    Stearns, M.E.3
  • 76
    • 0033959101 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion
    • D. Webb, D. Nguyen, and S. Gonias Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion J Cell Sci 113 2000 123 134
    • (2000) J Cell Sci , vol.113 , pp. 123-134
    • Webb, D.1    Nguyen, D.2    Gonias, S.3
  • 78
    • 67651007506 scopus 로고    scopus 로고
    • The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression
    • B. Fayard, F. Bianchi, J. Dey, E. Moreno, S. Djaffer, N.E. Hynes, and D. Monard The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression Cancer Res 69 2009 5690 5698
    • (2009) Cancer Res , vol.69 , pp. 5690-5698
    • Fayard, B.1    Bianchi, F.2    Dey, J.3    Moreno, E.4    Djaffer, S.5    Hynes, N.E.6    Monard, D.7
  • 79
    • 79952433556 scopus 로고    scopus 로고
    • A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion
    • U. Gopal, J.E. Bohonowych, C. Lema-Tome, A. Liu, E. Garrett-Mayer, B. Wang, and J.S. Isaacs A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion PLoS One 6 2011 e17649
    • (2011) PLoS One , vol.6 , pp. 17649
    • Gopal, U.1    Bohonowych, J.E.2    Lema-Tome, C.3    Liu, A.4    Garrett-Mayer, E.5    Wang, B.6    Isaacs, J.S.7
  • 80
    • 37249028744 scopus 로고    scopus 로고
    • Midkine and LDL-receptor-related protein 1 contribute to the anchorage-independent cell growth of cancer cells
    • S. Chen, G. Bu, Y. Takei, K. Sakamoto, S. Ikematsu, T. Muramatsu, and K. Kadomatsu Midkine and LDL-receptor-related protein 1 contribute to the anchorage-independent cell growth of cancer cells J Cell Sci 120 2007 4009 4015
    • (2007) J Cell Sci , vol.120 , pp. 4009-4015
    • Chen, S.1    Bu, G.2    Takei, Y.3    Sakamoto, K.4    Ikematsu, S.5    Muramatsu, T.6    Kadomatsu, K.7
  • 81
    • 59149098234 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9
    • H. Song, Y. Li, J. Lee, A.L. Schwartz, and G. Bu Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9 Cancer Res 69 2009 879 886
    • (2009) Cancer Res , vol.69 , pp. 879-886
    • Song, H.1    Li, Y.2    Lee, J.3    Schwartz, A.L.4    Bu, G.5
  • 82
    • 84870052886 scopus 로고    scopus 로고
    • Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis
    • N. Pencheva, H. Tran, C. Buss, D. Huh, M. Drobnjak, K. Busam, and S.F. Tavazoie Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis Cell 151 2012 1068 1082
    • (2012) Cell , vol.151 , pp. 1068-1082
    • Pencheva, N.1    Tran, H.2    Buss, C.3    Huh, D.4    Drobnjak, M.5    Busam, K.6    Tavazoie, S.F.7
  • 83
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • B.Z. Qian, and J.W. Pollard Macrophage diversity enhances tumor progression and metastasis Cell 141 2010 39 51
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 85
    • 0026693345 scopus 로고
    • Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain
    • B.B. Wolf, M.B. Lopes, S.R. VandenBerg, and S.L. Gonias Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain Am J Pathol 141 1992 37 42
    • (1992) Am J Pathol , vol.141 , pp. 37-42
    • Wolf, B.B.1    Lopes, M.B.2    Vandenberg, S.R.3    Gonias, S.L.4
  • 86
    • 33751104453 scopus 로고    scopus 로고
    • The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: Possible implications in peripheral nerve injury
    • W.M. Campana, X. Li, N. Dragojlovic, J. Janes, A. Gaultier, and S.L. Gonias The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: possible implications in peripheral nerve injury J Neurosci 26 2006 11197 11207
    • (2006) J Neurosci , vol.26 , pp. 11197-11207
    • Campana, W.M.1    Li, X.2    Dragojlovic, N.3    Janes, J.4    Gaultier, A.5    Gonias, S.L.6
  • 87
    • 0028180385 scopus 로고
    • Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells
    • M.B. Lopes, C.A. Bogaev, S.L. Gonias, and S.R. VandenBerg Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells FEBS Lett 338 1994 301 305
    • (1994) FEBS Lett , vol.338 , pp. 301-305
    • Lopes, M.B.1    Bogaev, C.A.2    Gonias, S.L.3    Vandenberg, S.R.4
  • 88
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • M.H. Barnett, and J.W. Prineas Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion Ann Neurol 55 2004 458 468
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 90
    • 84863504256 scopus 로고    scopus 로고
    • Apolipoprotein e and apolipoprotein e receptors: Normal biology and roles in Alzheimer disease
    • D.M. Holtzman, J. Herz, and G. Bu Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease Cold Spring Harb Perspect Med 2 2012 a006312
    • (2012) Cold Spring Harb Perspect Med , vol.2 , pp. 006312
    • Holtzman, D.M.1    Herz, J.2    Bu, G.3
  • 91
    • 68249134074 scopus 로고    scopus 로고
    • The role of apolipoprotein e in Alzheimer's disease
    • J. Kim, J.M. Basak, and D.M. Holtzman The role of apolipoprotein E in Alzheimer's disease Neuron 63 2009 287 303
    • (2009) Neuron , vol.63 , pp. 287-303
    • Kim, J.1    Basak, J.M.2    Holtzman, D.M.3
  • 92
    • 0020068202 scopus 로고
    • Extensive elongation of axons from rat brain into peripheral nerve grafts
    • M. Benfey, and A.J. Aguayo Extensive elongation of axons from rat brain into peripheral nerve grafts Nature 296 1982 150 152
    • (1982) Nature , vol.296 , pp. 150-152
    • Benfey, M.1    Aguayo, A.J.2
  • 96
    • 77952002192 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration
    • E. Mantuano, M. Jo, S. Gonias, and W. Campana Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration J Biol Chem 285 2010 14259 14266
    • (2010) J Biol Chem , vol.285 , pp. 14259-14266
    • Mantuano, E.1    Jo, M.2    Gonias, S.3    Campana, W.4
  • 97
    • 79751511360 scopus 로고    scopus 로고
    • Regulation of cytokine expression by Schwann cells in response to alpha2-macroglobulin binding to LRP1
    • Y. Shi, T. Yamauchi, A. Gaultier, S. Takimoto, W.M. Campana, and S.L. Gonias Regulation of cytokine expression by Schwann cells in response to alpha2-macroglobulin binding to LRP1 J Neurosci Res 89 2011 544 551
    • (2011) J Neurosci Res , vol.89 , pp. 544-551
    • Shi, Y.1    Yamauchi, T.2    Gaultier, A.3    Takimoto, S.4    Campana, W.M.5    Gonias, S.L.6
  • 99
    • 0034729210 scopus 로고    scopus 로고
    • Tissue plasminogen activator-mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury
    • K. Akassoglou, K. Kombrinck, J. Degen, and S. Strickland Tissue plasminogen activator-mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury J Cell Biol 149 2000 1157 1166
    • (2000) J Cell Biol , vol.149 , pp. 1157-1166
    • Akassoglou, K.1    Kombrinck, K.2    Degen, J.3    Strickland, S.4
  • 100
    • 68349131604 scopus 로고    scopus 로고
    • The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population
    • C. Toth, J. Lander, and S. Wiebe The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population Pain Med 10 2009 918 929
    • (2009) Pain Med , vol.10 , pp. 918-929
    • Toth, C.1    Lander, J.2    Wiebe, S.3


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