LRP: Role in vascular wall integrity and protection from atherosclerosis

Science

Volumn 300, Issue 5617, 2003, Pages 329-332

  Boucher, Philippe ^a   Gotthardt, Michael ^a   Li, Wei Ping ^b   Anderson, Richard G W ^b   Herz, Joachim ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTICITY; MUSCLE; SIGNALING;

ATHEROSCLEROSIS;

CELLS;

CHOLESTEROL; IMATINIB; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; UNCLASSIFIED DRUG;

BIOLOGY; CARDIOVASCULAR DISEASE; PROTEIN;

ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BLOOD VESSEL WALL; CELL MIGRATION; CELL PROLIFERATION; DRUG MECHANISM; ELASTICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; ARTERIOSCLEROSIS; CATTLE; CELL DIVISION; CELL LINE; CHOLESTEROL, DIETARY; DIET, ATHEROGENIC; ELASTIN; ENZYME INHIBITORS; LDL-RECEPTOR RELATED PROTEIN 1; LIGANDS; MESENTERIC ARTERIES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PIPERAZINES; PLATELET-DERIVED GROWTH FACTOR; PYRIMIDINES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0037432766     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1082095     Document Type: Article

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24. We thank J. Hayes and J. Stark for excellent technical assistance, K. Kamm for the gift of SMMHC antibody, P. Liu and R. E. Hammer for helpful discussions, and M. Brown and J. Goldstein for critical reading of the manuscript. Supported by grants from NIH (HL20948, HL63762, NS43408, and GM 52016), the Alzheimer's Association, the Humboldt Foundation, and the Perot Family Foundation.