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Volumn 122, Issue 8, 2009, Pages 1155-1162

Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis

Author keywords

Degeneration; Low density lipoprotein receptor related protein; Multiple sclerosis; Myelin; Myelin basic protein; Phagocytosis

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MESSENGER RNA; MYELIN BASIC PROTEIN; RAP PROTEIN; LIGAND; LOW DENSITY LIPOPROTEIN RECEPTOR; LRP1 PROTEIN, MOUSE; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN;

EID: 66849121678     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.040717     Document Type: Article
Times cited : (91)

References (55)
  • 1
    • 33947363967 scopus 로고    scopus 로고
    • The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease
    • Adams, R. A., Bauer, J., Flick, M. J., Sikorski, S. L., Nuriel, T., Lassmann, H., Degen, J. L. and Akassoglou, K. (2007). The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease. J. Exp. Med. 204, 571-582.
    • (2007) J. Exp. Med , vol.204 , pp. 571-582
    • Adams, R.A.1    Bauer, J.2    Flick, M.J.3    Sikorski, S.L.4    Nuriel, T.5    Lassmann, H.6    Degen, J.L.7    Akassoglou, K.8
  • 2
    • 0037458017 scopus 로고    scopus 로고
    • Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice
    • Akassoglou, K., Douni, E., Bauer, J., Lassmann, H., Kollias, G. and Probert, L. (2003). Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice. Proc. Natl. Acad. Sci. USA 100, 709-714.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 709-714
    • Akassoglou, K.1    Douni, E.2    Bauer, J.3    Lassmann, H.4    Kollias, G.5    Probert, L.6
  • 3
    • 53449099141 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator and the low density lipoprotein receptor-related protein induce Akt phosphorylation in the ischemic brain
    • An, J., Zhang, C., Polavarapu, R., Zhang, X., Zhang, X. and Yepes, M. (2008). Tissue-type plasminogen activator and the low density lipoprotein receptor-related protein induce Akt phosphorylation in the ischemic brain. Blood 112, 2787-2794.
    • (2008) Blood , vol.112 , pp. 2787-2794
    • An, J.1    Zhang, C.2    Polavarapu, R.3    Zhang, X.4    Zhang, X.5    Yepes, M.6
  • 5
    • 0033120990 scopus 로고    scopus 로고
    • Cutting edge: Receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells
    • Arnold-Schild, D., Hanau, D., Spehner, D., Schmid, C., Rammensee, H. G., de la Salle, H. and Schild, H. (1999). Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells. J. Immunol. 162, 3757-3760.
    • (1999) J. Immunol , vol.162 , pp. 3757-3760
    • Arnold-Schild, D.1    Hanau, D.2    Spehner, D.3    Schmid, C.4    Rammensee, H.G.5    de la Salle, H.6    Schild, H.7
  • 6
    • 0037784051 scopus 로고    scopus 로고
    • v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1
    • Barnes, H., Ackermann, E. J. and van der Geer, P. (2003). v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1. Oncogene 22, 3589-3597.
    • (2003) Oncogene , vol.22 , pp. 3589-3597
    • Barnes, H.1    Ackermann, E.J.2    van der Geer, P.3
  • 7
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett, M. H. and Prineas, J. W. (2004). Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann. Neurol. 55, 458-468.
    • (2004) Ann. Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 8
    • 0035070198 scopus 로고    scopus 로고
    • CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
    • Basu, S., Binder, R. J., Ramalingam, T. and Srivastava, P. K. (2001). CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin. Immunity 14, 303-313.
    • (2001) Immunity , vol.14 , pp. 303-313
    • Basu, S.1    Binder, R.J.2    Ramalingam, T.3    Srivastava, P.K.4
  • 9
    • 33748487414 scopus 로고    scopus 로고
    • Myelin basic protein: A multifunctional protein
    • Boggs, J. M. (2006). Myelin basic protein: a multifunctional protein. Cell Mol. Life Sci. 63, 1945-1961.
    • (2006) Cell Mol. Life Sci , vol.63 , pp. 1945-1961
    • Boggs, J.M.1
  • 10
    • 0034812412 scopus 로고    scopus 로고
    • The roles of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family
    • Bu, G. (2001). The roles of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family. Int. Rev. Cytol. 209, 79-116.
    • (2001) Int. Rev. Cytol , vol.209 , pp. 79-116
    • Bu, G.1
  • 12
    • 33751104453 scopus 로고    scopus 로고
    • The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: Possible implications in peripheral nerve injury
    • Campana, W. M., Li, X., Dragojlovic, N., Janes, J., Gaultier, A. and Gonias, S. L. (2006). The low-density lipoprotein receptor-related protein is a pro-survival receptor in Schwann cells: possible implications in peripheral nerve injury. J. Neurosci. 26, 11197-11207.
    • (2006) J. Neurosci , vol.26 , pp. 11197-11207
    • Campana, W.M.1    Li, X.2    Dragojlovic, N.3    Janes, J.4    Gaultier, A.5    Gonias, S.L.6
  • 16
    • 45949089484 scopus 로고    scopus 로고
    • Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor
    • Gaultier, A., Arandjelovic, S., Niessen, S., Overton, C. D., Linton, M. F., Fazio, S., Campana, W. M., Cravatt, B. F., 3rd and Gonias, S. L. (2008b). Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor. Blood 111, 5316-5325.
    • (2008) Blood , vol.111 , pp. 5316-5325
    • Gaultier, A.1    Arandjelovic, S.2    Niessen, S.3    Overton, C.D.4    Linton, M.F.5    Fazio, S.6    Campana, W.M.7    Cravatt 3rd, B.F.8    Gonias, S.L.9
  • 17
    • 0020381381 scopus 로고
    • A unique pathway for the plasma elimination of alpha 2-antiplasmin-protease complexes in mice
    • Gonias, S. L., Fuchs, H. E. and Pizzo, S. V. (1982). A unique pathway for the plasma elimination of alpha 2-antiplasmin-protease complexes in mice. Thromb. Haemost. 48, 208-210.
    • (1982) Thromb. Haemost , vol.48 , pp. 208-210
    • Gonias, S.L.1    Fuchs, H.E.2    Pizzo, S.V.3
  • 18
    • 3042664089 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein: Regulation of the plasma membrane proteome
    • Gonias, S. L., Wu, L. and Salicioni, A. M. (2004). Low density lipoprotein receptor-related protein: regulation of the plasma membrane proteome. Thromb. Haemost. 91, 1056-1064.
    • (2004) Thromb. Haemost , vol.91 , pp. 1056-1064
    • Gonias, S.L.1    Wu, L.2    Salicioni, A.M.3
  • 19
    • 0347994962 scopus 로고    scopus 로고
    • A CD91-positive subset of CD11c+ blood dendritic cells: Characterization of the APC that functions to enhance adaptive immune responses against CD91-targeted antigens
    • Hart, J. P., Gunn, M. D. and Pizzo, S. V. (2004). A CD91-positive subset of CD11c+ blood dendritic cells: characterization of the APC that functions to enhance adaptive immune responses against CD91-targeted antigens. J. Immunol. 172, 70-78.
    • (2004) J. Immunol , vol.172 , pp. 70-78
    • Hart, J.P.1    Gunn, M.D.2    Pizzo, S.V.3
  • 20
    • 0034836428 scopus 로고    scopus 로고
    • LRP: A multifunctional scavenger and signaling receptor
    • Herz, J. and Strickland, D. K. (2001). LRP: a multifunctional scavenger and signaling receptor. J. Clin. Invest. 108, 779-784.
    • (2001) J. Clin. Invest , vol.108 , pp. 779-784
    • Herz, J.1    Strickland, D.K.2
  • 21
    • 0025786502 scopus 로고
    • 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor
    • Herz, J., Goldstein, J. L., Strickland, D. K., Ho, Y. K. and Brown, M. S. (1991). 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. J. Biol. Chem. 266, 21232-21238.
    • (1991) J. Biol. Chem , vol.266 , pp. 21232-21238
    • Herz, J.1    Goldstein, J.L.2    Strickland, D.K.3    Ho, Y.K.4    Brown, M.S.5
  • 22
    • 0026439778 scopus 로고
    • LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation
    • Herz, J., Clouthier, D. E. and Hammer, R. E. (1992). LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation. Cell 71, 411-421.
    • (1992) Cell , vol.71 , pp. 411-421
    • Herz, J.1    Clouthier, D.E.2    Hammer, R.E.3
  • 23
    • 0029143336 scopus 로고
    • Expression and distribution of low density lipoprotein receptor-related protein mRNA in the rat central nervous system
    • Ishiguro, M., Imai, Y. and Kohsaka, S. (1995). Expression and distribution of low density lipoprotein receptor-related protein mRNA in the rat central nervous system. Brain Res. Mol. Brain Res. 33, 37-46.
    • (1995) Brain Res. Mol. Brain Res , vol.33 , pp. 37-46
    • Ishiguro, M.1    Imai, Y.2    Kohsaka, S.3
  • 24
    • 0030341635 scopus 로고    scopus 로고
    • Regulation of myelin development
    • Kamholz, J. A. (1996). Regulation of myelin development. Mult. Scler. 2, 236-240.
    • (1996) Mult. Scler , vol.2 , pp. 236-240
    • Kamholz, J.A.1
  • 25
    • 0024990661 scopus 로고
    • Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis: Pathogenetic and clinical implications
    • Kermode, A. G., Thompson, A. J., Tofts, P., MacManus, D. G., Kendall, B. E., Kingsley, D. P., Moseley, I. F., Rudge, P. and McDonald, W. I. (1990). Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis: pathogenetic and clinical implications. Brain 113, 1477-1489.
    • (1990) Brain , vol.113 , pp. 1477-1489
    • Kermode, A.G.1    Thompson, A.J.2    Tofts, P.3    MacManus, D.G.4    Kendall, B.E.5    Kingsley, D.P.6    Moseley, I.F.7    Rudge, P.8    McDonald, W.I.9
  • 26
    • 50349092250 scopus 로고    scopus 로고
    • LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies
    • Lillis, A. P., Van Duyn, L. B., Murphy-Ullrich, J. E. and Strickland, D. K. (2008). LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol. Rev. 88, 887-918.
    • (2008) Physiol. Rev , vol.88 , pp. 887-918
    • Lillis, A.P.1    Van Duyn, L.B.2    Murphy-Ullrich, J.E.3    Strickland, D.K.4
  • 27
    • 0028180385 scopus 로고
    • Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells
    • Lopes, M. B., Bogaev, C. A., Gonias, S. L. and VandenBerg, S. R. (1994). Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells. FEBS Lett. 338, 301-305.
    • (1994) FEBS Lett , vol.338 , pp. 301-305
    • Lopes, M.B.1    Bogaev, C.A.2    Gonias, S.L.3    VandenBerg, S.R.4
  • 28
    • 0345633543 scopus 로고    scopus 로고
    • A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases
    • Lucchinetti, C., Bruck, W., Parisi, J., Scheithauer, B., Rodriguez, M. and Lassmann, H. (1999). A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain 122, 2279-2295.
    • (1999) Brain , vol.122 , pp. 2279-2295
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 29
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • Lucchinetti, C., Bruck, W., Parisi, J., Scheithauer, B., Rodriguez, M. and Lassmann, H. (2000). Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann. Neurol. 47, 707-717.
    • (2000) Ann. Neurol , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 30
    • 3843127502 scopus 로고    scopus 로고
    • Evidence for pathogenic heterogeneity in multiple sclerosis
    • Lucchinetti, C. F., Bruck, W. and Lassmann, H. (2004). Evidence for pathogenic heterogeneity in multiple sclerosis. Ann. Neurol. 56, 308.
    • (2004) Ann. Neurol , vol.56 , pp. 308
    • Lucchinetti, C.F.1    Bruck, W.2    Lassmann, H.3
  • 32
    • 0034194071 scopus 로고    scopus 로고
    • Expression of alpha(2)-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells
    • Marzolo, M. P., von Bernhardi, R., Bu, G. and Inestrosa, N. C. (2000). Expression of alpha(2)-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells. J. Neurosci. Res. 60, 401-411.
    • (2000) J. Neurosci. Res , vol.60 , pp. 401-411
    • Marzolo, M.P.1    von Bernhardi, R.2    Bu, G.3    Inestrosa, N.C.4
  • 35
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • McCarthy, K. D. and de Vellis, J. (1980). Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 85, 890-902.
    • (1980) J. Cell Biol , vol.85 , pp. 890-902
    • McCarthy, K.D.1    de Vellis, J.2
  • 36
    • 0026731852 scopus 로고
    • Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues
    • Moestrup, S. K., Gliemann, J. and Pallesen, G. (1992). Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues. Cell Tissue Res. 269, 375-382.
    • (1992) Cell Tissue Res , vol.269 , pp. 375-382
    • Moestrup, S.K.1    Gliemann, J.2    Pallesen, G.3
  • 37
    • 1842356008 scopus 로고
    • Recombination within the myelin basic protein gene created the dysmyelinating shiverer mouse mutation
    • Molineaux, S. M., Engh, H., de Ferra, F., Hudson, L. and Lazzarini, R. A. (1986). Recombination within the myelin basic protein gene created the dysmyelinating shiverer mouse mutation. Proc. Natl. Acad. Sci. USA 83, 7542-7546.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7542-7546
    • Molineaux, S.M.1    Engh, H.2    de Ferra, F.3    Hudson, L.4    Lazzarini, R.A.5
  • 38
    • 33645210449 scopus 로고    scopus 로고
    • Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope
    • Musse, A. A., Boggs, J. M. and Harauz, G. (2006). Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope. Proc. Natl. Acad. Sci. USA 103, 4422-4427.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4422-4427
    • Musse, A.A.1    Boggs, J.M.2    Harauz, G.3
  • 39
    • 0015857284 scopus 로고
    • Myelination in rat brain: Method of myelin isolation
    • Norton, W. T. and Poduslo, S. E. (1973). Myelination in rat brain: method of myelin isolation. J. Neurochem. 21, 749-757.
    • (1973) J. Neurochem , vol.21 , pp. 749-757
    • Norton, W.T.1    Poduslo, S.E.2
  • 40
    • 0030926412 scopus 로고    scopus 로고
    • Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes
    • Nykjaer, A., Conese, M., Christensen, E. I., Olson, D., Cremona, O., Gliemann, J. and Blasi, F. (1997). Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes. EMBO J. 16, 2610-2620.
    • (1997) EMBO J , vol.16 , pp. 2610-2620
    • Nykjaer, A.1    Conese, M.2    Christensen, E.I.3    Olson, D.4    Cremona, O.5    Gliemann, J.6    Blasi, F.7
  • 41
    • 0025370870 scopus 로고
    • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
    • Ota, K., Matsui, M., Milford, E. L., Mackin, G. A., Weiner, H. L. and Hafler, D. A. (1990). T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 346, 183-187.
    • (1990) Nature , vol.346 , pp. 183-187
    • Ota, K.1    Matsui, M.2    Milford, E.L.3    Mackin, G.A.4    Weiner, H.L.5    Hafler, D.A.6
  • 43
    • 0033568616 scopus 로고    scopus 로고
    • Characterization of the soluble form of the low density lipoprotein receptor-related protein (LRP)
    • Quinn, K. A., Pye, V. J., Dai, Y. P., Chesterman, C. N. and Owensby, D. A. (1999). Characterization of the soluble form of the low density lipoprotein receptor-related protein (LRP). Exp. Cell Res. 251, 433-441.
    • (1999) Exp. Cell Res , vol.251 , pp. 433-441
    • Quinn, K.A.1    Pye, V.J.2    Dai, Y.P.3    Chesterman, C.N.4    Owensby, D.A.5
  • 44
    • 0029346926 scopus 로고
    • Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune encephalomyelitis: An investigation using rat radiation bone marrow chimeras
    • Rinner, W. A., Bauer, J., Schmidts, M., Lassmann, H. and Hickey, W. F. (1995). Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune encephalomyelitis: an investigation using rat radiation bone marrow chimeras. Glia 14, 257-266.
    • (1995) Glia , vol.14 , pp. 257-266
    • Rinner, W.A.1    Bauer, J.2    Schmidts, M.3    Lassmann, H.4    Hickey, W.F.5
  • 45
    • 35748946007 scopus 로고    scopus 로고
    • Role of megalin, a proximal tubular endocytic receptor, in calcium and phosphate homeostasis
    • Saito, A., Iino, N., Takeda, T. and Gejyo, F. (2007). Role of megalin, a proximal tubular endocytic receptor, in calcium and phosphate homeostasis. Ther. Apher. Dial. 11 Suppl. 1, S23-S26.
    • (2007) Ther. Apher. Dial , vol.11 , Issue.SUPPL. 1
    • Saito, A.1    Iino, N.2    Takeda, T.3    Gejyo, F.4
  • 47
    • 0035879567 scopus 로고    scopus 로고
    • Phagocytic properties of microglia in vitro: Implications for a role in multiple sclerosis and EAE
    • Smith, M. E. (2001). Phagocytic properties of microglia in vitro: implications for a role in multiple sclerosis and EAE. Microsc. Res. Tech. 54, 81-94.
    • (2001) Microsc. Res. Tech , vol.54 , pp. 81-94
    • Smith, M.E.1
  • 48
    • 0031025835 scopus 로고    scopus 로고
    • Autoimmune pathogenesis of multiple sclerosis: Role of autoreactive T lymphocytes and new immunotherapeutic strategies
    • Stinissen, P., Raus, J. and Zhang, J. (1997). Autoimmune pathogenesis of multiple sclerosis: role of autoreactive T lymphocytes and new immunotherapeutic strategies. Crit. Rev. Immunol. 17, 33-75.
    • (1997) Crit. Rev. Immunol , vol.17 , pp. 33-75
    • Stinissen, P.1    Raus, J.2    Zhang, J.3
  • 51
    • 0036785571 scopus 로고    scopus 로고
    • Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: Calreticulin and CD91 as a common collectin receptor complex
    • Vandivier, R. W., Ogden, C. A., Fadok, V. A., Hoffmann, P. R., Brown, K. K., Botto, M., Walport, M. J., Fisher, J. H., Henson, P. M. and Greene, K. E. (2002). Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex. J. Immunol. 169, 3978-3986.
    • (2002) J. Immunol , vol.169 , pp. 3978-3986
    • Vandivier, R.W.1    Ogden, C.A.2    Fadok, V.A.3    Hoffmann, P.R.4    Brown, K.K.5    Botto, M.6    Walport, M.J.7    Fisher, J.H.8    Henson, P.M.9    Greene, K.E.10
  • 53
    • 0028343888 scopus 로고
    • Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A: Evidence that this protein is required for uptake and degradation of multiple ligands
    • Willnow, T. E. and Herz, J. (1994). Genetic deficiency in low density lipoprotein receptor-related protein confers cellular resistance to Pseudomonas exotoxin A: evidence that this protein is required for uptake and degradation of multiple ligands. J. Cell Sci. 107, 719-726.
    • (1994) J. Cell Sci , vol.107 , pp. 719-726
    • Willnow, T.E.1    Herz, J.2
  • 54
    • 0026693345 scopus 로고
    • Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain
    • Wolf, B. B., Lopes, M. B., VandenBerg, S. R. and Gonias, S. L. (1992). Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain. Am. J. Pathol. 141, 37-42.
    • (1992) Am. J. Pathol , vol.141 , pp. 37-42
    • Wolf, B.B.1    Lopes, M.B.2    VandenBerg, S.R.3    Gonias, S.L.4
  • 55
    • 0345824713 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein
    • Yepes, M., Sandkvist, M., Moore, E. G., Bugge, T. H., Strickland, D. K. and Lawrence, D. A. (2003). Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. J. Clin. Invest. 112, 1533-1540.
    • (2003) J. Clin. Invest , vol.112 , pp. 1533-1540
    • Yepes, M.1    Sandkvist, M.2    Moore, E.G.3    Bugge, T.H.4    Strickland, D.K.5    Lawrence, D.A.6


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