Macrophage LRP-1 controls plaque cellularity by regulating efferocytosis and Akt activation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 4, 2010, Pages 787-795

  Yancey, Patricia G ^a   Blakemore, John ^a   Ding, Lei ^a   Fan, Daping ^a   Overton, Cheryl D ^b   Zhang, Youmin ^a   Linton, MacRae F ^a,c   Fazio, Sergio ^a,b  

^a Atherosclerosis Research Unit   (United States)

^b Department of Pathology ^*  (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apolipoprotein E; Apoptosis; Efferocytosis; Inflammation; LRP 1; Necrosis

Indexed keywords

APOLIPOPROTEIN E; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN ASSOCIATED PROTEIN; MESSENGER RNA; PROTEIN KINASE B; LOW DENSITY LIPOPROTEIN; LRP1 PROTEIN, MOUSE; OXIDIZED LOW DENSITY LIPOPROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL DEATH; CHOLESTEROL TRANSPORT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MOUSE; NECROSIS; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE; ANIMAL; CELL CULTURE; CELL SURVIVAL; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETICS; METABOLISM; MOUSE MUTANT; NICK END LABELING; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; FEMALE; IN SITU NICK-END LABELING; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LIPOPROTEINS, LDL; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; NECROSIS; PHAGOCYTOSIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, LDL; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS;

EID: 77950888338     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.202051     Document Type: Article

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