The functional role of the second NPXY motif of the LRP1 β-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors

Journal of Biological Chemistry

Volumn 283, Issue 18, 2008, Pages 12004-12013

  Martin, Anne M ^a   Kuhlmann, Christoph ^a   Trossbach, Svenja ^a   Jaeger, Sebastian ^a   Waldron, Elaine ^a   Roebroek, Anton ^b   Luhmann, Heiko J ^a   Laatsch, Alexander ^c   Weggen, Sascha ^d   Lessmann, Volkmar ^e   Pietrzik, Claus U ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; CALCIUM; CALCIUM ALLOYS; FLOW INTERACTIONS; ORGANIC ACIDS;

ACTIVATED PROTEIN KINASES; ADAPTOR PROTEINS; AMINO ACID MOTIFS; ASPARTATE; ASPARTATE RECEPTORS; BINDING MOTIFS; C TERMINUSES; CALCIUM INFLUXES; CELLULAR SIGNALING PATHWAYS; DO-MAINS; EXPERIMENTAL APPROACHES; FUNCTIONAL INTERACTIONS; FUNCTIONAL ROLES; GATING MECHANISMS; LOW DENSITY LIPOPROTEIN RECEPTORS; MITOGEN; NMDA RECEPTORS; PLASMINOGEN ACTIVATORS; SERINE PROTEINASES;

CHEMICAL ACTIVATION;

ADAPTOR PROTEIN; DIZOCILPINE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POSTSYNAPTIC DENSITY PROTEIN 95; TISSUE PLASMINOGEN ACTIVATOR; CALCIUM; DLGH4 PROTEIN, MOUSE; MEMBRANE PROTEIN; SIGNAL PEPTIDE; SMALL INTERFERING RNA;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NERVE CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; INTRACELLULAR SPACE; METABOLISM; MOUSE; PHOSPHORYLATION; PLASMID; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CELL LINE; ENZYME ACTIVATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SPACE; LDL-RECEPTOR RELATED PROTEIN 1; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONS; PHOSPHORYLATION; PLASMIDS; PROTEIN STRUCTURE, SECONDARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR CROSS-TALK; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE PLASMINOGEN ACTIVATOR;

EID: 45549088806     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707607200     Document Type: Article

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