-
1
-
-
70350764945
-
Trends in cardiovascular mortality in patients with rheumatoid arthritis over 50 years: A systematic review and meta-analysis of cohort studies
-
Meune C, Tousé E, Trinquart L, Allanore Y. Trends in cardiovascular mortality in patients with rheumatoid arthritis over 50 years: a systematic review and meta-analysis of cohort studies. Rheumatology (Oxford). 2009;48:1309-1313.
-
(2009)
Rheumatology (Oxford)
, vol.48
, pp. 1309-1313
-
-
Meune, C.1
Tousé, E.2
Trinquart, L.3
Allanore, Y.4
-
2
-
-
0034121235
-
Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins
-
MacGregor AJ, Snieder H, Rigby AS, et al. Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum. 2000;43:30-37.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 30-37
-
-
Macgregor, A.J.1
Snieder, H.2
Rigby, A.S.3
-
3
-
-
0027375302
-
Twin concordance rates for rheumatoid arthritis: Results from a nationwide study
-
Silman AJ, MacGregor AJ, Thomson W, et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol. 1993;32:903-907.
-
(1993)
Br J Rheumatol
, vol.32
, pp. 903-907
-
-
Silman, A.J.1
Macgregor, A.J.2
Thomson, W.3
-
4
-
-
84865375172
-
Rheumatoid arthritis: From autoimmunity to synovitis and joint destruction
-
Boissier MC, Semerano L, Challal S, Saidenberg-Kermanac KN, Falgarone G. Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction. J Autoimmun. 2012;39:222-228.
-
(2012)
J Autoimmun
, vol.39
, pp. 222-228
-
-
Boissier, M.C.1
Semerano, L.2
Challal, S.3
Saidenberg-Kermanac, K.N.4
Falgarone, G.5
-
5
-
-
84883548680
-
Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis
-
Arvikar SL, Collier DS, Fisher MC, et al. Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis. Arthritis Res Ther. 2013;15:R109.
-
(2013)
Arthritis Res Ther
, vol.15
-
-
Arvikar, S.L.1
Collier, D.S.2
Fisher, M.C.3
-
6
-
-
18744430797
-
Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis
-
Rantapaa-Dahlqvist S, de Jong BA, Berglin E, et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum. 2003;48: 2741-2749.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2741-2749
-
-
Rantapaa-Dahlqvist, S.1
de Jong, B.A.2
Berglin, E.3
-
7
-
-
67449124634
-
Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: The RAPID 2 study. A randomised controlled trial
-
Smolen J, Landewé RB, Mease P, et al. Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial. Ann Rheum Dis. 2009;68: 797-804.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 797-804
-
-
Smolen, J.1
Landewé, R.B.2
Mease, P.3
-
8
-
-
67449133560
-
Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: The GO-FORWARD Study
-
Keystone EC, Genovese MC, Klareskog L, et al. Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study. Ann Rheum Dis. 2009;68:789-796.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 789-796
-
-
Keystone, E.C.1
Genovese, M.C.2
Klareskog, L.3
-
9
-
-
34447336406
-
Long-term infliximab treatment in rheumatoid arthritis: Subsequent outcome of initial responders
-
Buch MH, Bingham SJ, Bryer D, Emery P. Long-term infliximab treatment in rheumatoid arthritis: subsequent outcome of initial responders. Rheumatology (Oxford). 2007;46:1153-1156.
-
(2007)
Rheumatology (Oxford)
, vol.46
, pp. 1153-1156
-
-
Buch, M.H.1
Bingham, S.J.2
Bryer, D.3
Emery, P.4
-
10
-
-
0031712994
-
Correlation of serum IgA rheumatoid factor levels with disease severity in rheumatoid arthritis
-
Pai S, Pai L, Birkenfeldt R. Correlation of serum IgA rheumatoid factor levels with disease severity in rheumatoid arthritis. Scand J Rheumatol. 1998;27:252-256.
-
(1998)
Scand J Rheumatol
, vol.27
, pp. 252-256
-
-
Pai, S.1
Pai, L.2
Birkenfeldt, R.3
-
11
-
-
27844575688
-
Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis
-
van der Helm-van Mil AH, Verpoort KN, Breedveld FC, Toes RE, Huizinga TW. Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis. Arthritis Res Ther. 2005;7: R949-R958.
-
(2005)
Arthritis Res Ther
, vol.7
-
-
van der Helm-van Mil, A.H.1
Verpoort, K.N.2
Breedveld, F.C.3
Toes, R.E.4
Huizinga, T.W.5
-
12
-
-
33646483031
-
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
-
Emery P, Fleischmann R, Filipowicz-Sosnowska A, et al. The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum. 2006;54:1390-1400.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1390-1400
-
-
Emery, P.1
Fleischmann, R.2
Filipowicz-Sosnowska, A.3
-
13
-
-
78650645377
-
Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: The IMAGE trial
-
Tak PP, Rigby WF, Rubbert-Roth A, et al. Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial. Ann Rheum Dis. 2011;70:39-46.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 39-46
-
-
Tak, P.P.1
Rigby, W.F.2
Rubbert-Roth, A.3
-
14
-
-
77951777466
-
Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: Results from the SUNRISE trial
-
Mease PJ, Cohen S, Gaylis NB, et al. Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: results from the SUNRISE trial. J Rheumatol. 2010;37:917-927.
-
(2010)
J Rheumatol
, vol.37
, pp. 917-927
-
-
Mease, P.J.1
Cohen, S.2
Gaylis, N.B.3
-
15
-
-
54949129325
-
Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis
-
Dass S, Rawstron AC, Vital EM, Henshaw K, McGonagle D, Emery P. Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis. Arthritis Rheum. 2008;58:2993-2999.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2993-2999
-
-
Dass, S.1
Rawstron, A.C.2
Vital, E.M.3
Henshaw, K.4
McGonagle, D.5
Emery, P.6
-
16
-
-
79953679566
-
Reduced-dose rituximab in rheumatoid arthritis
-
Vital EM, Rawstron AC, Dass S, et al. Reduced-dose rituximab in rheumatoid arthritis. Arthritis Rheum. 2011;63:603-608.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 603-608
-
-
Vital, E.M.1
Rawstron, A.C.2
Dass, S.3
-
17
-
-
67449152722
-
Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation
-
Teng YK, Levarht EW, Toes RE, Huizinga TW, van Laar JM. Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation. Ann Rheum Dis. 2009;68:1011-1016.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1011-1016
-
-
Teng, Y.K.1
Levarht, E.W.2
Toes, R.E.3
Huizinga, T.W.4
van Laar, J.M.5
-
18
-
-
82455210480
-
Blood memory B cells are disturbed and predict the response to rituximab in patients with rheumatoid arthritis
-
Sellam J, Rouanet S, Hendel-Chavez H, et al. Blood memory B cells are disturbed and predict the response to rituximab in patients with rheumatoid arthritis. Arthritis Rheum. 2011;63:3692-3701.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3692-3701
-
-
Sellam, J.1
Rouanet, S.2
Hendel-Chavez, H.3
-
20
-
-
32444447885
-
Reconstitution of peripheral blood B cells after depletion with rituximab in patients with rheumatoid arthritis
-
Leandro MJ, Cambridge G, Ehrenstein MR, Edwards JCW. Reconstitution of peripheral blood B cells after depletion with rituximab in patients with rheumatoid arthritis. Arthritis Rheum. 2006;54:613-620.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 613-620
-
-
Leandro, M.J.1
Cambridge, G.2
Ehrenstein, M.R.3
Edwards, J.C.W.4
-
21
-
-
45349102781
-
Anti-CD20 therapy in patients with rheumatoid arthritis: Predictors of response and B cell subset regeneration after repeated treatment
-
Roll P, Dörner T, Tony HP. Anti-CD20 therapy in patients with rheumatoid arthritis: predictors of response and B cell subset regeneration after repeated treatment. Arthritis Rheum. 2008;58:1566-1575.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1566-1575
-
-
Roll, P.1
Dörner, T.2
Tony, H.P.3
-
22
-
-
14844347864
-
Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis
-
O'Neill SK, Shlomchik MJ, Glant TT, Cao Y, Doodes PD, Finnegan A. Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis. J Immunol. 2005;174:3781-3788.
-
(2005)
J Immunol
, vol.174
, pp. 3781-3788
-
-
O'Neill, S.K.1
Shlomchik, M.J.2
Glant, T.T.3
Cao, Y.4
Doodes, P.D.5
Finnegan, A.6
-
23
-
-
0033577903
-
A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
-
Chan OT, Hannum LG, Haberman AM, Madaio MP, Shlomchik MJ. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med. 1999;189:1639-1648.
-
(1999)
J Exp Med
, vol.189
, pp. 1639-1648
-
-
Chan, O.T.1
Hannum, L.G.2
Haberman, A.M.3
Madaio, M.P.4
Shlomchik, M.J.5
-
24
-
-
58149316141
-
B cells play a crucial role as antigen-presenting cells and collaborate with inflammatory cytokines in glucose-6-phosphate isomerase-induced arthritis
-
Tanaka-Watanabe Y, Matsumoto I, Iwanami K, et al. B cells play a crucial role as antigen-presenting cells and collaborate with inflammatory cytokines in glucose-6-phosphate isomerase-induced arthritis. Clin Exp Immunol. 2009;155:285-294.
-
(2009)
Clin Exp Immunol
, vol.155
, pp. 285-294
-
-
Tanaka-Watanabe, Y.1
Matsumoto, I.2
Iwanami, K.3
-
25
-
-
0035888030
-
T cell activation in rheumatoid synovium is B cell dependent
-
Takemura S, Klimiuk PA, Brown A, Goronzy JJ, Weyand CM. T cell activation in rheumatoid synovium is B cell dependent. J Immunol. 2001;167:4710-4718.
-
(2001)
J Immunol
, vol.167
, pp. 4710-4718
-
-
Takemura, S.1
Klimiuk, P.A.2
Brown, A.3
Goronzy, J.J.4
Weyand, C.M.5
-
27
-
-
84871664898
-
To B or not to B: The conducter of rheumatoid arthritis orchestra
-
Moura RA, Graça L, Fonseca JE. To B or not to B: the conducter of rheumatoid arthritis orchestra. Clin Rev Allergy Immunol. 2012;43: 281-291.
-
(2012)
Clin Rev Allergy Immunol
, vol.43
, pp. 281-291
-
-
Moura, R.A.1
Graça, L.2
Fonseca, J.E.3
-
28
-
-
0006379753
-
Affinity maturation without germinal centres in lymphotoxin-alpha-deficient mice
-
Matsumoto M, Lo SF, Carruthers CJ, et al. Affinity maturation without germinal centres in lymphotoxin-alpha-deficient mice. Nature. 2006;382:462-466.
-
(2006)
Nature
, vol.382
, pp. 462-466
-
-
Matsumoto, M.1
Lo, S.F.2
Carruthers, C.J.3
-
29
-
-
0032127288
-
Lymph node genesis is induced by signaling through the lymphotoxin beta receptor
-
Rennert PD, James D, Mackay F, Browning JL, Hochman PS. Lymph node genesis is induced by signaling through the lymphotoxin beta receptor. Immunity. 1998;9:71-79.
-
(1998)
Immunity
, vol.9
, pp. 71-79
-
-
Rennert, P.D.1
James, D.2
Mackay, F.3
Browning, J.L.4
Hochman, P.S.5
-
30
-
-
79955806071
-
Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis
-
Buch MH, Smolen JS, Betteridge N, et al. Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis. Ann Rheum Dis. 2011;70:909-920.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 909-920
-
-
Buch, M.H.1
Smolen, J.S.2
Betteridge, N.3
-
31
-
-
33747203086
-
Immunopathologic role of B lymphocytes in rheumatoid arthritis: Rational of B cell-directed therapy
-
Martinez-Gamboa L, Brezinschek HP, Burmester GR, Dörner T. Immunopathologic role of B lymphocytes in rheumatoid arthritis: rational of B cell-directed therapy. Autoimmun Rev. 2006;5:437-442.
-
(2006)
Autoimmun Rev
, vol.5
, pp. 437-442
-
-
Martinez-Gamboa, L.1
Brezinschek, H.P.2
Burmester, G.R.3
Dörner, T.4
-
32
-
-
73349104126
-
Rituximab therapy reduces antivated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: Depletion of memory B cells correlates with clinical response
-
Nakou M, Katsikas G, Sidiropoulos P, et al. Rituximab therapy reduces antivated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response. Arthritis Res Ther. 2009;11:R131.
-
(2009)
Arthritis Res Ther
, vol.11
-
-
Nakou, M.1
Katsikas, G.2
Sidiropoulos, P.3
-
33
-
-
39549100140
-
Assessment of rituximab's immunomodulatory synovial effects (ARISE trial). 1: Clinical and synovial biomarker results
-
Kavanaugh A, Rosengren S, Lee SJ, et al. Assessment of rituximab's immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results. Ann Rheum Dis. 2008;67:402-408.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 402-408
-
-
Kavanaugh, A.1
Rosengren, S.2
Lee, S.J.3
-
34
-
-
84855709532
-
Rituximab restored the muscle power and rescued from a refractory fatal respiratory failure in a patient with elderly-onset polymyositis
-
Gheita TA, Gheita HA, Kenawy SA. Rituximab restored the muscle power and rescued from a refractory fatal respiratory failure in a patient with elderly-onset polymyositis. Joint Bone Spine. 2012;79: 101-102.
-
(2012)
Joint Bone Spine
, vol.79
, pp. 101-102
-
-
Gheita, T.A.1
Gheita, H.A.2
Kenawy, S.A.3
-
35
-
-
77955738274
-
Efficacy and safety of various repeat treatment dosing regimens of rituximab in patients with active rheumatoid arthritis: Results of a phase III randomized study (MIRROR)
-
Rubbert-Roth A, Tak PP, Zerbini C, et al. Efficacy and safety of various repeat treatment dosing regimens of rituximab in patients with active rheumatoid arthritis: results of a phase III randomized study (MIRROR). Rheumatology (Oxford). 2010;49:1683-1693.
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 1683-1693
-
-
Rubbert-Roth, A.1
Tak, P.P.2
Zerbini, C.3
-
36
-
-
33746961890
-
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
-
Cohen SB, Emery P, Greenwald MW, et al. Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum. 2006;54:2793-2806.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2793-2806
-
-
Cohen, S.B.1
Emery, P.2
Greenwald, M.W.3
-
37
-
-
84870330803
-
Multiple courses of rituximab produce sustained clinical and radiographic efficacy and safety in patients with rheumatoid arthritis and an inadequate response to 1 or more tumor necrosis factor inhibitors: 5-year data from the REFLEX study
-
Keystone EC, Cohen SB, Emery P, et al. Multiple courses of rituximab produce sustained clinical and radiographic efficacy and safety in patients with rheumatoid arthritis and an inadequate response to 1 or more tumor necrosis factor inhibitors: 5-year data from the REFLEX study. J Rheumatol. 2012;39:2238-2246.
-
(2012)
J Rheumatol
, vol.39
, pp. 2238-2246
-
-
Keystone, E.C.1
Cohen, S.B.2
Emery, P.3
-
38
-
-
84867404092
-
Comparative effectiveness of switching to alternative tumour necrosis factor (TNF) antagonists versus switching to rituximab in patients with rheumatoid arthritis who failed previous TNF antagonists: The MIRAR Study
-
Gomez-Reino JJ, Maneiro JR, Ruiz J, et al. Comparative effectiveness of switching to alternative tumour necrosis factor (TNF) antagonists versus switching to rituximab in patients with rheumatoid arthritis who failed previous TNF antagonists: the MIRAR Study. Ann Rheum Dis. 2012;71:1861-1864.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 1861-1864
-
-
Gomez-Reino, J.J.1
Maneiro, J.R.2
Ruiz, J.3
-
39
-
-
84864454091
-
Rituximab or a second anti-tumor necrosis factor therapy for rheumatoid arthritis patients who have failed their first anti-tumor necrosis factor therapy? Comparative analysis from the British Society for Rheumatology Biologics Register
-
Soliman MM, Hyrich KL, Lunt M, Watson KD, Symmons DP, Ashcroft DM. Rituximab or a second anti-tumor necrosis factor therapy for rheumatoid arthritis patients who have failed their first anti-tumor necrosis factor therapy? Comparative analysis from the British Society for Rheumatology Biologics Register. Arthritis Care Res. 2012;64:1108-1115.
-
(2012)
Arthritis Care Res
, vol.64
, pp. 1108-1115
-
-
Soliman, M.M.1
Hyrich, K.L.2
Lunt, M.3
Watson, K.D.4
Symmons, D.P.5
Ashcroft, D.M.6
-
40
-
-
77955896561
-
Efficacy and safety of different doses and retreatment of rituximab: A randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE)
-
Emery P, Deodhar A, Rigby WF, et al. Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE). Ann Rheum Dis. 2010;69:1629-1635.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1629-1635
-
-
Emery, P.1
Deodhar, A.2
Rigby, W.F.3
-
41
-
-
84857238587
-
Effectiveness of disease-modifying antirheumatic drug co-therapy with methotrexate and leflunomide in rituximab-treated rheumatoid arthritis patients: Results of a 1-year follow-up study from the CERERRA collaboration
-
Chatzidionysiou K, Lie E, Nasonov E, et al. Effectiveness of disease-modifying antirheumatic drug co-therapy with methotrexate and leflunomide in rituximab-treated rheumatoid arthritis patients: results of a 1-year follow-up study from the CERERRA collaboration. Ann Rheum Dis. 2012;71:374-377.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 374-377
-
-
Chatzidionysiou, K.1
Lie, E.2
Nasonov, E.3
-
42
-
-
77953696525
-
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatid drugs
-
Smolen JS, Landewé R, Breedveld FC, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatid drugs. Ann Rheum Dis. 2010;69:964-975.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 964-975
-
-
Smolen, J.S.1
Landewé, R.2
Breedveld, F.C.3
-
43
-
-
84859832981
-
Update of the 2008 American College of Rheumatology recommendations for the use of diseas-modifying antirheumatic drugs and biologic agents in the treatment of theumatoid arthritis
-
Singh JA, Furst DE, Bharat A, et al. 2012 Update of the 2008 American College of Rheumatology recommendations for the use of diseas-modifying antirheumatic drugs and biologic agents in the treatment of theumatoid arthritis. Arthritis Care Res (Hoboken). 2012;64:625-639.
-
(2012)
Arthritis Care Res (Hoboken)
, vol.64
, pp. 625-639
-
-
Singh, J.A.1
Furst, D.E.2
Bharat, A.3
-
44
-
-
47949114181
-
B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis
-
Cantaert T, Kolln J, Timmer T, et al. B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis. J Immunol. 2008;181:785-794.
-
(2008)
J Immunol
, vol.181
, pp. 785-794
-
-
Cantaert, T.1
Kolln, J.2
Timmer, T.3
-
45
-
-
79955094058
-
Factors implicated in the generation and persistence of long-lived plasma cell-mediated autoimmunity
-
Neves M, Alves JD. Factors implicated in the generation and persistence of long-lived plasma cell-mediated autoimmunity. Autoimmun Rev. 2011;10:375-382.
-
(2011)
Autoimmun Rev
, vol.10
, pp. 375-382
-
-
Neves, M.1
Alves, J.D.2
-
46
-
-
59249104722
-
Ectopic lymphoid structures support ongoing production of class-switch autoantibodies in rheumatoid synovium
-
Humby F, Bombardieri M, Manzo A, et al. Ectopic lymphoid structures support ongoing production of class-switch autoantibodies in rheumatoid synovium. PLoS Med. 2009;6:59-75.
-
(2009)
PLoS Med
, vol.6
, pp. 59-75
-
-
Humby, F.1
Bombardieri, M.2
Manzo, A.3
-
47
-
-
0030664045
-
Tissue cytokine patterns distinguishes variants of rheumatoid synovitis
-
Klimiuk PA, Goronzy JJ, Björnsson J, Beckenbaugh RD, Weyand CM. Tissue cytokine patterns distinguishes variants of rheumatoid synovitis. Am J Pathol. 1997;151:1311-1319.
-
(1997)
Am J Pathol
, vol.151
, pp. 1311-1319
-
-
Klimiuk, P.A.1
Goronzy, J.J.2
Björnsson, J.3
Beckenbaugh, R.D.4
Weyand, C.M.5
-
48
-
-
0033818367
-
Histology of the synovium tissue: Value of semi-quantitative analysis for the prediction of joint erosions in rheumatoid arthritis
-
Fonseca JE, Canhão H, Resende C, et al. Histology of the synovium tissue: value of semi-quantitative analysis for the prediction of joint erosions in rheumatoid arthritis. Clin Exp Rheumatol. 2000;18:559-564.
-
(2000)
Clin Exp Rheumatol
, vol.18
, pp. 559-564
-
-
Fonseca, J.E.1
Canhão, H.2
Resende, C.3
-
49
-
-
84868675342
-
Rational of anti-CD19 immunotherapy: An option to target autoreactive plasma cells in autoimmunity
-
Mei HE, Schmidt S, Dörner T. Rational of anti-CD19 immunotherapy: an option to target autoreactive plasma cells in autoimmunity. Arthritis Res Ther. 2012;14 Suppl 5:S1.
-
(2012)
Arthritis Res Ther
, Issue.14 SUPPL. 5
-
-
Mei, H.E.1
Schmidt, S.2
Dörner, T.3
-
50
-
-
27244432745
-
Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease
-
Yazawa N, Hamaguchi Y, Poe JC, Tedder TF. Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease. Proc Natl Acad Sci U S A. 2005;102:15178-15183.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15178-15183
-
-
Yazawa, N.1
Hamaguchi, Y.2
Poe, J.C.3
Tedder, T.F.4
-
51
-
-
15444368773
-
The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice
-
Hamaguchi Y, Uchida J, Cain DW, et al. The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. J Immunol. 2005;174:4389-4399.
-
(2005)
J Immunol
, vol.174
, pp. 4389-4399
-
-
Hamaguchi, Y.1
Uchida, J.2
Cain, D.W.3
-
52
-
-
70349973753
-
CD19: A promising B cell target for rheumatoid arthritis
-
Tedder TF. CD19: a promising B cell target for rheumatoid arthritis. Nat Rev Rheumatol. 2009;5:572-577.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 572-577
-
-
Tedder, T.F.1
-
53
-
-
9444268741
-
A Phase I study of bolus versus continuous infusion of the anti-CD19 immunotoxin, IgG-HD37-dgA, in patients with B-cell lymphoma
-
Stone MJ, Sausville EA, Fay JW, et al. A Phase I study of bolus versus continuous infusion of the anti-CD19 immunotoxin, IgG-HD37-dgA, in patients with B-cell lymphoma. Blood. 1996;88:1188-1197.
-
(1996)
Blood
, vol.88
, pp. 1188-1197
-
-
Stone, M.J.1
Sausville, E.A.2
Fay, J.W.3
-
54
-
-
84864544136
-
Phase I multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma
-
Younes A, Kim S, Romaguera J, et al. Phase I multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma. J Clin Oncol. 2012;30:2776-2782.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2776-2782
-
-
Younes, A.1
Kim, S.2
Romaguera, J.3
-
55
-
-
84872191194
-
Belimumab - an anti-BLyS human monoclonal antibody for rheumatoid arthritis
-
Jin X, Ding C. Belimumab - an anti-BLyS human monoclonal antibody for rheumatoid arthritis. Expert Opin Biol Ther. 2013;13:315-322.
-
(2013)
Expert Opin Biol Ther
, vol.13
, pp. 315-322
-
-
Jin, X.1
Ding, C.2
-
56
-
-
79959832697
-
Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: Results of a Phase II, randomized, placebo-controlled, dose-finding trial
-
Genovese MC, Kinnman N, de La Bourdonnaye G, Pena Rossi C, Tak PP. Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: results of a Phase II, randomized, placebo-controlled, dose-finding trial. Arthritis Rheum. 2011;63:1793-1803.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1793-1803
-
-
Genovese, M.C.1
Kinnman, N.2
de La Bourdonnaye, G.3
Pena, R.C.4
Tak, P.P.5
-
57
-
-
84876889502
-
Efficacy and safety of belimumab in patients with rheumatoid arthritis: A Phase II, randomized, double-blind, placebo-controlled, dose-ranging study
-
Stohl W, Merrill JT, McKay JD, et al. Efficacy and safety of belimumab in patients with rheumatoid arthritis: a Phase II, randomized, double-blind, placebo-controlled, dose-ranging study. J Rheumatol. 2013;40: 579-589.
-
(2013)
J Rheumatol
, vol.40
, pp. 579-589
-
-
Stohl, W.1
Merrill, J.T.2
McKay, J.D.3
-
58
-
-
79959856423
-
Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate
-
van Vollenhoven RF, Kinnman N, Vincent E, Wax S, Bathon J. Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate. Arthritis Rheum. 2011;63:1782-1792.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1782-1792
-
-
van Vollenhoven, R.F.1
Kinnman, N.2
Vincent, E.3
Wax, S.4
Bathon, J.5
-
59
-
-
77957004137
-
B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin
-
Dillon SR, Harder B, Lewis KB, et al. B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin. Arthritis Res Ther. 2010;12: R48.
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Dillon, S.R.1
Harder, B.2
Lewis, K.B.3
-
60
-
-
73249118620
-
Etiology and pathogenesis of rheumatoid arthritis
-
Firestein GS, Budd RC, Harris EDJ, McInnes IB, Ruddy S, Sergent JS, editors, Philadelphia, PA: Saunders
-
Firestein GS. Etiology and pathogenesis of rheumatoid arthritis. In: Firestein GS, Budd RC, Harris EDJ, McInnes IB, Ruddy S, Sergent JS, editors. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, PA: Saunders; 2009.
-
(2009)
Kelley's Textbook of Rheumatology. 8th Ed
-
-
Firestein, G.S.1
-
61
-
-
33646490259
-
Interleukin-17 acts independently of TNF-alpha under arthritic conditions
-
Koenders MI, Lubberts E, van de Loo FAJ, et al. Interleukin-17 acts independently of TNF-alpha under arthritic conditions. J Immunol. 2006;176:6262-6269.
-
(2006)
J Immunol
, vol.176
, pp. 6262-6269
-
-
Koenders, M.I.1
Lubberts, E.2
van de Loo, F.A.J.3
-
62
-
-
57149107119
-
The effects of IL-6 on CD4 T cell responses
-
Dienz O, Rincon M. The effects of IL-6 on CD4 T cell responses. Clin Immunol. 2009;130:27-33.
-
(2009)
Clin Immunol
, vol.130
, pp. 27-33
-
-
Dienz, O.1
Rincon, M.2
-
63
-
-
77953980528
-
IL-6: From its discovery to clinical applications
-
Kishimoto T. IL-6: from its discovery to clinical applications. Int Immunol. 2010;22:347-352.
-
(2010)
Int Immunol
, vol.22
, pp. 347-352
-
-
Kishimoto, T.1
-
64
-
-
84888199536
-
Altered Th17 cells and Th17/regulatory T-cell ratios indicate the subsequent conversion from undifferentiated connective tissue disease to definitive systemic autoimmune disorders
-
August 20, Epub ahead of print
-
Szodoray P, Nakken B, Barath S, et al. Altered Th17 cells and Th17/regulatory T-cell ratios indicate the subsequent conversion from undifferentiated connective tissue disease to definitive systemic autoimmune disorders. Hum Immunol. August 20, 2013.[Epub ahead of print.]
-
(2013)
Hum Immunol
-
-
Szodoray, P.1
Nakken, B.2
Barath, S.3
-
65
-
-
84883297026
-
CD45RA-Foxp3high activated/effector regulatory T cells in the CCR7+CD45RA-CD27+CD28+ central memory subset are the decreased in peripheral blood from patients with rheumatoid arthritis
-
Matsuki F, Saegusa J, Miyamoto Y, Misaki K, Kumagai S, Morinobu A. CD45RA-Foxp3high activated/effector regulatory T cells in the CCR7+CD45RA-CD27+CD28+ central memory subset are the decreased in peripheral blood from patients with rheumatoid arthritis. Biochem Biophys Res Commun. 2013;438:778-783.
-
(2013)
Biochem Biophys Res Commun
, vol.438
, pp. 778-783
-
-
Matsuki, F.1
Saegusa, J.2
Miyamoto, Y.3
Misaki, K.4
Kumagai, S.5
Morinobu, A.6
-
66
-
-
70349969840
-
Regulatory T cells as therapeutic targets in rheumatoid arthritis
-
Esensten JH, Wofsy D, Bluestone JA. Regulatory T cells as therapeutic targets in rheumatoid arthritis. Nat Rev Rheumatol. 2009;5:560-565.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 560-565
-
-
Esensten, J.H.1
Wofsy, D.2
Bluestone, J.A.3
-
67
-
-
84883606628
-
Defective CD8+CD28- regulatory T cell suppressor function in rheumatoid arthritis is restored by TNF inihibitor therapy
-
Ceeraz S, Hall C, Choy E, Spencer J, Corrigall VM. Defective CD8+CD28- regulatory T cell suppressor function in rheumatoid arthritis is restored by TNF inihibitor therapy. Clin Exp Immunol. 2013;174: 18-26.
-
(2013)
Clin Exp Immunol
, vol.174
, pp. 18-26
-
-
Ceeraz, S.1
Hall, C.2
Choy, E.3
Spencer, J.4
Corrigall, V.M.5
-
68
-
-
84940217378
-
The impact of conventional DMARD and biological therapies on CD4+ cell subsets in rheumatoid arthritis: A follow-up study
-
August 11, Epub ahead of print
-
Szalay B, Vásárhelyi B, Cseh A, et al. The impact of conventional DMARD and biological therapies on CD4+ cell subsets in rheumatoid arthritis: a follow-up study. Clin Rheumatol. August 11, 2013. [Epub ahead of print.]
-
(2013)
Clin Rheumatol
-
-
Szalay, B.1
Vásárhelyi, B.2
Cseh, A.3
-
69
-
-
84869430125
-
T-cell agents in the treatment of rheumatoid arthritis
-
Solomon GE. T-cell agents in the treatment of rheumatoid arthritis. Bull NYU Hosp Jt Dis. 2012;70:191-194.
-
(2012)
Bull NYU Hosp Jt Dis
, vol.70
, pp. 191-194
-
-
Solomon, G.E.1
-
70
-
-
67549119579
-
Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: A histological, gene expression and dynamic magnetic resonance imaging pilot study
-
Buch MH, Boyle DL, Rosengren S, et al. Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study. Ann Rheum Dis. 2009;68:1220-1227.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1220-1227
-
-
Buch, M.H.1
Boyle, D.L.2
Rosengren, S.3
-
71
-
-
33750992180
-
Reduction of inflammatory biomarker response by abatacept in treatment of rheumatoid arthritis
-
Weisman MH, Durez P, Hallegua D, et al. Reduction of inflammatory biomarker response by abatacept in treatment of rheumatoid arthritis. J Rheumatol. 2006;33:2162-2166.
-
(2006)
J Rheumatol
, vol.33
, pp. 2162-2166
-
-
Weisman, M.H.1
Durez, P.2
Hallegua, D.3
-
73
-
-
84867401801
-
Positivity for anti-cyclic citrullinated peptide is associated with a better response to abatacept: Data from the 'Orencia and Rheumatoid Arthritis' registry
-
Gottenberg JE, Ravaud P, Cantagrel A, et al. Positivity for anti-cyclic citrullinated peptide is associated with a better response to abatacept: data from the 'Orencia and Rheumatoid Arthritis' registry. Ann Rheum Dis. 2012;71:1815-1819.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 1815-1819
-
-
Gottenberg, J.E.1
Ravaud, P.2
Cantagrel, A.3
-
74
-
-
33745291091
-
Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: A randomized trial
-
Kremer JM, Genant HK, Moreland LW, et al. Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial. Ann Intern Med. 2006;144:865-876.
-
(2006)
Ann Intern Med
, vol.144
, pp. 865-876
-
-
Kremer, J.M.1
Genant, H.K.2
Moreland, L.W.3
-
75
-
-
47949106400
-
Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: A phase III, multi-centre, randomised, doubleblind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate
-
Schiff M, Keiserman M, Codding C, et al. Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, doubleblind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate. Ann Rheum Dis. 2008;67:1096-1103.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1096-1103
-
-
Schiff, M.1
Keiserman, M.2
Codding, C.3
-
76
-
-
24944498854
-
Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition
-
Genovese MC, Becker JC, Schiff M, et al. Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med. 2005;353:1114-1123.
-
(2005)
N Engl J Med
, vol.353
, pp. 1114-1123
-
-
Genovese, M.C.1
Becker, J.C.2
Schiff, M.3
-
77
-
-
80053571696
-
Clinical response and tolerability to abatacept in patients with rheumatoid arthritis previously treated with infliximab or abatacept: Open-label extension of the ATTEST Study
-
Schiff M, Keiserman M, Codding C, et al. Clinical response and tolerability to abatacept in patients with rheumatoid arthritis previously treated with infliximab or abatacept: open-label extension of the ATTEST Study. Ann Rheum Dis. 2011;70:2003-2007.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 2003-2007
-
-
Schiff, M.1
Keiserman, M.2
Codding, C.3
-
78
-
-
70449709528
-
The 6-month safety and efficacy of abatacept in patients with rheumatoid arthritis who underwent a washout after anti-tumour necrosis factor therapy or were directly switched to abatacept: The ARRIVE trial
-
Schiff M, Pritchard C, Huffstutter JE, et al. The 6-month safety and efficacy of abatacept in patients with rheumatoid arthritis who underwent a washout after anti-tumour necrosis factor therapy or were directly switched to abatacept: the ARRIVE trial. Ann Rheum Dis. 2009;68: 1708-1714.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1708-1714
-
-
Schiff, M.1
Pritchard, C.2
Huffstutter, J.E.3
-
79
-
-
65349176911
-
Clinical efficacy and safety of abatacept in methotrexate naive patients with early rheumatoid arthritis and poor prognostic factors
-
Westhovens R, Robles M, Ximenes AC, et al. Clinical efficacy and safety of abatacept in methotrexate naive patients with early rheumatoid arthritis and poor prognostic factors. Ann Rheum Dis. 2009;68: 1870-1877.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1870-1877
-
-
Westhovens, R.1
Robles, M.2
Ximenes, A.C.3
-
80
-
-
84878155949
-
Subcutaneous abatacept for the treatment of rheumatoid arthritis
-
Schiff M. Subcutaneous abatacept for the treatment of rheumatoid arthritis. Rheumatology (Oxford). 2013;52:986-997.
-
(2013)
Rheumatology (Oxford)
, vol.52
, pp. 986-997
-
-
Schiff, M.1
-
81
-
-
84876701598
-
Immunogenicity, safety, and efficacy of abatacept administered subcutaneously with or without background methotrexate in patients with rheumatoid arthritis: Results from a phase III, international, multicenter, parallel-arm, open-label study
-
Nash P, Nayiager S, Genovese MC, et al. Immunogenicity, safety, and efficacy of abatacept administered subcutaneously with or without background methotrexate in patients with rheumatoid arthritis: results from a phase III, international, multicenter, parallel-arm, open-label study. Arthritis Care Res (Hoboken). 2013;65:718-728.
-
(2013)
Arthritis Care Res (Hoboken)
, vol.65
, pp. 718-728
-
-
Nash, P.1
Nayiager, S.2
Genovese, M.C.3
-
82
-
-
84881041617
-
CTLA4-Ig (abatacept) therapy modulates T cell effector functions in autoantibody-positive rheumatoid arthritis patients
-
Pieper J, Herrath J, Raghavan S, Muhammad K, van Vollenhoven R, Malmström V. CTLA4-Ig (abatacept) therapy modulates T cell effector functions in autoantibody-positive rheumatoid arthritis patients. BMC Immunol. 2013;14:34.
-
(2013)
BMC Immunol
, vol.14
, pp. 34
-
-
Pieper, J.1
Herrath, J.2
Raghavan, S.3
Muhammad, K.4
van Vollenhoven, R.5
Malmström, V.6
-
83
-
-
33846853779
-
Selective co-stimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: A randomized clinical trial
-
Weinblatt M, Schiff M, Goldman A, et al. Selective co-stimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: a randomized clinical trial. Ann Rheum Dis. 2007;66:228-234.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 228-234
-
-
Weinblatt, M.1
Schiff, M.2
Goldman, A.3
-
84
-
-
55849095891
-
Evidence that cytokines play a role in rheumatoid arthritis
-
Brennen FM, McLnnes IV. Evidence that cytokines play a role in rheumatoid arthritis. J Clin Invest. 2008;118:3537-3545.
-
(2008)
J Clin Invest
, vol.118
, pp. 3537-3545
-
-
Brennen, F.M.1
McLnnes, I.V.2
-
85
-
-
84863861008
-
Understanding the dynamics: Pathways involved in the pathogenesis of rheumatoid arthritis
-
Choy E. Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis. Rheumatology (Oxford). 2012;51 Suppl 5:v3-v11.
-
(2012)
Rheumatology (Oxford)
, Issue.51 SUPPL. 5
-
-
Choy, E.1
-
86
-
-
74849102659
-
Rapid and sustained improvement in bone and cartilage turnover markers with the anti-interleukin-6 receptor inhibitor tocilizumab plus methotrexate in rheumatoid arthritis patients with an inadequate response to methotrexate
-
Gernero P, Thompson E, Woodworth T, Smolen JS. Rapid and sustained improvement in bone and cartilage turnover markers with the anti-interleukin-6 receptor inhibitor tocilizumab plus methotrexate in rheumatoid arthritis patients with an inadequate response to methotrexate. Arthritis Rheum. 2010;62:33-43.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 33-43
-
-
Gernero, P.1
Thompson, E.2
Woodworth, T.3
Smolen, J.S.4
-
87
-
-
77955096184
-
Therapeutic targets in rheumatoid arthritis: The interleukin-6 receptor
-
Dayer JM, Choy E. Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor. Rheumatology (Oxford). 2010;49:15-24.
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 15-24
-
-
Dayer, J.M.1
Choy, E.2
-
88
-
-
0025483386
-
Binding of low density lipoprotein (LDL) to C-reactive protein (CRP): A possible binding through apolipoprotein B in LDL at phosphorylcholine-binding site of CRP
-
Japanese
-
Nunomura W, Hatakeyama M. [Binding of low density lipoprotein (LDL) to C-reactive protein (CRP): a possible binding through apolipoprotein B in LDL at phosphorylcholine-binding site of CRP]. Hokkaido Igaku Zasshi. 1990;65:474-480.Japanese.
-
(1990)
Hokkaido Igaku Zasshi
, vol.65
, pp. 474-480
-
-
Nunomura, W.1
Hatakeyama, M.2
-
89
-
-
77955980286
-
Metabolic syndrome and carotid intima-media thickness in young adults: Roles of apolipoprotein B, apolipoprotein A-I, C-reactive protein, and secretory phospholipase A2: The cardiovascular risk in young Finns study
-
Mattsson N, Magnussen CG, Rönnemaa T, et al. Metabolic syndrome and carotid intima-media thickness in young adults: roles of apolipoprotein B, apolipoprotein A-I, C-reactive protein, and secretory phospholipase A2: the cardiovascular risk in young Finns study. Arterioscler Thromb Vasc Biol. 2010;30:1861-1866.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1861-1866
-
-
Mattsson, N.1
Magnussen, C.G.2
Rönnemaa, T.3
-
90
-
-
0034100717
-
Role of serum amyloid A during metabolism of acute-phase HDL by macrophages
-
Artl A, Marsche G, Lestavel S, Sattler W, Malle E. Role of serum amyloid A during metabolism of acute-phase HDL by macrophages. Arterioscler Thromb Vasc Biol. 2000;20:763-772.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 763-772
-
-
Artl, A.1
Marsche, G.2
Lestavel, S.3
Sattler, W.4
Malle, E.5
-
91
-
-
0029049806
-
Serum amyloid A (SAA): Influence on HDL-mediated cellular cholesterol efflux
-
Banka CL, Yuan T, de Beer MC, Kindy M, Curtiss LK, de Beer FC. Serum amyloid A (SAA): influence on HDL-mediated cellular cholesterol efflux. J Lipid Res. 1995;36:1058-1065.
-
(1995)
J Lipid Res
, vol.36
, pp. 1058-1065
-
-
Banka, C.L.1
Yuan, T.2
de Beer, M.C.3
Kindy, M.4
Curtiss, L.K.5
de Beer, F.C.6
-
92
-
-
84875809836
-
Serum amyloid A stimulates macrophage foam cell formation via lectin-like oxidized low-density lipoprotein receptor 1 upregulation
-
Lee HY, Kim SD, Baek SH, et al. Serum amyloid A stimulates macrophage foam cell formation via lectin-like oxidized low-density lipoprotein receptor 1 upregulation. Biochem Biophys Res Commun. 2013;433:18-23.
-
(2013)
Biochem Biophys Res Commun
, vol.433
, pp. 18-23
-
-
Lee, H.Y.1
Kim, S.D.2
Baek, S.H.3
-
93
-
-
79951739491
-
Interleukin-6 inhibition for treatment of rheumatoid arthritis: A review of tocilizumab therapy
-
Patel AM, Moreland LW. Interleukin-6 inhibition for treatment of rheumatoid arthritis: a review of tocilizumab therapy. Drug Des Dev Ther. 2010;4:263-278.
-
(2010)
Drug Des Dev Ther
, vol.4
, pp. 263-278
-
-
Patel, A.M.1
Moreland, L.W.2
-
94
-
-
40749114497
-
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): A double-blind, placebo-controlled, randomized trial
-
Smolen JS, Beaulieu A, Rubbert-Roth A, et al. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomized trial. Lancet. 2008;371:987-997.
-
(2008)
Lancet
, vol.371
, pp. 987-997
-
-
Smolen, J.S.1
Beaulieu, A.2
Rubbert-Roth, A.3
-
95
-
-
84873600423
-
Tocilizumab inhibits structural joint damage and improves physical function in patients with rheumatoid arthritis and inadequate responses to methotrexate: LITHE study 2-year results
-
Fleischmann RM, Halland AM, Brzosko M, et al. Tocilizumab inhibits structural joint damage and improves physical function in patients with rheumatoid arthritis and inadequate responses to methotrexate: LITHE study 2-year results. J Rheumatol. 2013;40(2):113-126.
-
(2013)
J Rheumatol
, vol.40
, Issue.2
, pp. 113-126
-
-
Fleischmann, R.M.1
Halland, A.M.2
Brzosko, M.3
-
96
-
-
54949150604
-
Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to diseasemodifying antirheumatic drugs: The tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study
-
Genovese MC, McKay JD, Nasonov EL, et al. Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to diseasemodifying antirheumatic drugs: the tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study. Arthritis Rheum. 2008;58(10):2968-2980.
-
(2008)
Arthritis Rheum
, vol.58
, Issue.10
, pp. 2968-2980
-
-
Genovese, M.C.1
McKay, J.D.2
Nasonov, E.L.3
-
97
-
-
54949150604
-
Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to diseasemodifying antirheumatic drugs: The tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study
-
Genovese MC, McKay JD, Nasonov EL, et al. Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to diseasemodifying antirheumatic drugs: the tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study. Arthritis Rheum. 2008;58(10):2968-2980.
-
(2008)
Arthritis Rheum
, vol.58
, Issue.10
, pp. 2968-2980
-
-
Genovese, M.C.1
McKay, J.D.2
Nasonov, E.L.3
-
98
-
-
84871093047
-
Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)
-
Dougados M, Kissel K, Sheeran T, et al. Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY). Ann Rheum Dis. 2013;72:43-50.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 43-50
-
-
Dougados, M.1
Kissel, K.2
Sheeran, T.3
-
99
-
-
73449118587
-
Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: The AMBITION study
-
Jones G, Sebba A, Gu J, et al. Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study. Ann Rheum Dis. 2010;69(1):88-96.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.1
, pp. 88-96
-
-
Jones, G.1
Sebba, A.2
Gu, J.3
-
100
-
-
67549107120
-
Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: A systematic literature research
-
Salliot C, van der Heijde D. Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research. Ann Rheum Dis. 2009;68:1100-1104.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1100-1104
-
-
Salliot, C.1
van der Heijde, D.2
-
101
-
-
77956229543
-
Lipid profile and cardiovascular risk in patients with rheumatoid arthritis: Effect of the disease and of drug therapy
-
French
-
Hansel B, Bruckert E. [Lipid profile and cardiovascular risk in patients with rheumatoid arthritis: effect of the disease and of drug therapy]. Ann Endocrinol (Paris). 2010;71:257-263.French.
-
(2010)
Ann Endocrinol (Paris)
, vol.71
, pp. 257-263
-
-
Hansel, B.1
Bruckert, E.2
-
102
-
-
84890301704
-
Patient with a 9-year history of rheumatoid arthritis and hepatitis B co-infection who responds favorably to tocilizumab monotherapy after progression or intolerance to several disease-modifying anti-rheumatic drugs
-
Oliveira S. Patient with a 9-year history of rheumatoid arthritis and hepatitis B co-infection who responds favorably to tocilizumab monotherapy after progression or intolerance to several disease-modifying anti-rheumatic drugs. Adv Ther. 2012;29 Special Issue:12-13.
-
(2012)
Adv Ther
, vol.29
, pp. 12-13
-
-
Oliveira, S.1
-
103
-
-
84869797922
-
IL-6 Trans-signaling via the soluble IL-6 receptor: Importance for the pro-inflammatory activities of IL-6
-
Rose-John S. IL-6 Trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6. Int J Biol Sci. 2012;8:1237-1247.
-
(2012)
Int J Biol Sci
, vol.8
, pp. 1237-1247
-
-
Rose-John, S.1
-
104
-
-
59849091830
-
Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis
-
Nowell MA, Williams AS, Carty SA, et al. Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis. J Immunol. 2009;182:613-622.
-
(2009)
J Immunol
, vol.182
, pp. 613-622
-
-
Nowell, M.A.1
Williams, A.S.2
Carty, S.A.3
-
105
-
-
79957656408
-
Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model
-
Barkhausen T, Tschernig T, Rosenstiel P, et al. Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model. Crit Care Med. 2011;39:1407-1413.
-
(2011)
Crit Care Med
, vol.39
, pp. 1407-1413
-
-
Barkhausen, T.1
Tschernig, T.2
Rosenstiel, P.3
-
106
-
-
33847351136
-
The JAK-STAT signaling pathway: Input and output integration
-
Murray PJ. The JAK-STAT signaling pathway: input and output integration. J Immunol. 2007;178:2623-2629.
-
(2007)
J Immunol
, vol.178
, pp. 2623-2629
-
-
Murray, P.J.1
-
107
-
-
84877767875
-
JAK inhibitor tofacitinib for treating rheumatoid arthritis: From basic to clinical
-
Tanaka Y, Yamaoka K. JAK inhibitor tofacitinib for treating rheumatoid arthritis: from basic to clinical. Mod Rheumatol. 2013;23:415-424.
-
(2013)
Mod Rheumatol
, vol.23
, pp. 415-424
-
-
Tanaka, Y.1
Yamaoka, K.2
-
108
-
-
84874402383
-
Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve-month data from a twenty-four-month phase III randomized radiographic study
-
van der Heijde D, Tanaka Y, Fleischmann R, et al. Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: twelve-month data from a twenty-four-month phase III randomized radiographic study. Arthritis Rheum. 2013;65(3):559-570.
-
(2013)
Arthritis Rheum
, vol.65
, Issue.3
, pp. 559-570
-
-
van der Heijde, D.1
Tanaka, Y.2
Fleischmann, R.3
-
109
-
-
84864716411
-
Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis
-
Fleischmann R, Kremer J, Cush J, et al. Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis. N Eng J Med. 2012;367(6):495-507.
-
(2012)
N Eng J Med
, vol.367
, Issue.6
, pp. 495-507
-
-
Fleischmann, R.1
Kremer, J.2
Cush, J.3
-
110
-
-
84864703156
-
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
-
van Vollenhoven RF, Fleischmann R, Cohen S, et al. Tofacitinib or adalimumab versus placebo in rheumatoid arthritis. N Eng J Med. 2012;367(6):508-519.
-
(2012)
N Eng J Med
, vol.367
, Issue.6
, pp. 508-519
-
-
van Vollenhoven, R.F.1
Fleischmann, R.2
Cohen, S.3
-
111
-
-
84882266430
-
Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: A randomized trial
-
Kremer J, Li ZG, Hall S, et al. Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial. Ann Intern Med. 2013;159(4):253-261.
-
(2013)
Ann Intern Med
, vol.159
, Issue.4
, pp. 253-261
-
-
Kremer, J.1
Li, Z.G.2
Hall, S.3
-
112
-
-
17444394445
-
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
-
Bresnihan B, Alvaro-Gracia JM, Cobby M, et al. Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum. 1998;41:2196-2204.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2196-2204
-
-
Bresnihan, B.1
Alvaro-Gracia, J.M.2
Cobby, M.3
-
113
-
-
0036190776
-
Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial
-
Cohen S, Hurd E, Cush J, et al. Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2002;46:614-624.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 614-624
-
-
Cohen, S.1
Hurd, E.2
Cush, J.3
-
114
-
-
3442885115
-
A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate
-
Cohen SB, Moreland LW, Cush JJ, et al. A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann Rheum Dis. 2004;63:1062-1068.
-
(2004)
Ann Rheum Dis
, vol.63
, pp. 1062-1068
-
-
Cohen, S.B.1
Moreland, L.W.2
Cush, J.J.3
-
115
-
-
77953547828
-
Efficacy and safety of anakinra for the treatment of rheumatoid arthritis: An update of the Oregon Drug Effectiveness Review Project
-
Thaler K, Chandiramani DV, Hansen RA, Gerald G. Efficacy and safety of anakinra for the treatment of rheumatoid arthritis: an update of the Oregon Drug Effectiveness Review Project. Biologics. 2009;3: 485-498.
-
(2009)
Biologics
, vol.3
, pp. 485-498
-
-
Thaler, K.1
Chandiramani, D.V.2
Hansen, R.A.3
Gerald, G.4
-
116
-
-
84872858296
-
Which are the antibodies to watch in 2013?
-
Reichert JM. Which are the antibodies to watch in 2013? MAbs. 2013;5: 1-4.
-
(2013)
MAbs
, vol.5
, pp. 1-4
-
-
Reichert, J.M.1
-
117
-
-
84863012323
-
Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: Results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group phase III trial
-
Tak PP, Mease PJ, Genovese MC, et al. Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group phase III trial. Arthritis Rheum. 2012;64:360-370.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 360-370
-
-
Tak, P.P.1
Mease, P.J.2
Genovese, M.C.3
-
118
-
-
84856388514
-
Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate - results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group Phase III trial
-
Rigby W, Tony HP, Oelke K, et al. Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate - results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group Phase III trial. Arthritis Rheum. 2012;64:350-359.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 350-359
-
-
Rigby, W.1
Tony, H.P.2
Oelke, K.3
-
119
-
-
84871046740
-
Rituximab dissociates the tight link between disease activity and joint damage in rheumatoid arthritis patients
-
Aletaha D, Alasti F, Smolen JS. Rituximab dissociates the tight link between disease activity and joint damage in rheumatoid arthritis patients. Ann Rheum Dis. 2013;72:7-12.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 7-12
-
-
Aletaha, D.1
Alasti, F.2
Smolen, J.S.3
-
120
-
-
84859517375
-
Tocilizumab inhibits progression of joint damage in rheumatoid arthritis irrespective of its anti-inflammatory effects: Dissociation of the link between inflammation and destruction
-
Smolen JS, Martinez Avila JC, Aletaha D. Tocilizumab inhibits progression of joint damage in rheumatoid arthritis irrespective of its anti-inflammatory effects: dissociation of the link between inflammation and destruction. Ann Rheum Dis. 2012;71:687-693.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 687-693
-
-
Smolen, J.S.1
Martinez, A.J.C.2
Aletaha, D.3
|