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Clinical efficacy and safety of abatacept in methotrexatenaive patients with early rheumatoid arthritis and poor prognostic factors
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84878672843
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Disease remission, normalized physical function and radiographic non-progression are achieved by the majority of patients with early rheumatoid arthritis treated with abatacept + methotrexate: results from the 2-year AGREE trial. Poster SAT0178
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Westhovens R, Durez P, Genant H, Robles M, Becker JC, Covucci A, et al. Disease remission, normalized physical function and radiographic non-progression are achieved by the majority of patients with early rheumatoid arthritis treated with abatacept + methotrexate: results from the 2-year AGREE trial. Poster SAT0178, EULAR Annual Congress, June 16-19, 2010.
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EULAR Annual Congress, June 16-19, 2010
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Westhovens, R.1
Durez, P.2
Genant, H.3
Robles, M.4
Becker, J.C.5
Covucci, A.6
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9
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Radiographic progression correlates well with patient-reported RAPID3 disease activity levels in methotrexate (MTX).naive patients with early rheumatoid arthritis (RA): Insights from the AGREE study
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Keystone E, Westhovens R, Moniz Reed D, Covucci A, Wells A. Radiographic progression correlates well with patient-reported RAPID3 disease activity levels in methotrexate (MTX).naive patients with early rheumatoid arthritis (RA): insights from the AGREE study. Arthritis & Rheumatism. 2010;62(10 Suppl):S470.
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33745291091
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Abatacept improves disease activity status over time in patients with rheumatoid arthritis and an inadequate response to methotrexate
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abstract
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Dougados M, Kremer JM, Le Bars M, Reed D, Park S, Vatsanos G, et al. Abatacept improves disease activity status over time in patients with rheumatoid arthritis and an inadequate response to methotrexate [abstract]. Ann Rheum Dis. 2009;68:573.
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12
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47949106400
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Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: A phase III, multi-centre, randomised, doubleblind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate
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Schiff M, Keiserman M, Codding C, Songcharoen S, Berman A, Nayiager S, et al. Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, doubleblind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate. Ann Rheum Dis. 2008;67:1096-103.
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13
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84878674507
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Abatacept increases the proportion of patients who remain free from structural damage progression through 5 years in methotrexate inadequate responders with rheumatoid arthritis. Poster FRI0253
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Genant HK, Peterfy C, Westhovens R, Becker JC, Vratsanos G, Zhou X, et al. Abatacept increases the proportion of patients who remain free from structural damage progression through 5 years in methotrexate inadequate responders with rheumatoid arthritis. Poster FRI0253, EULAR Annual Congress, June 10-13, 2009.
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EULAR Annual Congress, June 10-13, 2009
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Genant, H.K.1
Peterfy, C.2
Westhovens, R.3
Becker, J.C.4
Vratsanos, G.5
Zhou, X.6
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14
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24944498854
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Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition
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Genovese, M.C.1
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Kremer, J.6
Birbara, C.7
Box, J.8
Natarajan, K.9
Nuamah, I.10
Li, T.11
Aranda, R.12
Hagerty, D.T.13
Dougados, M.14
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24944498854
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Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition
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DOI 10.1056/NEJMoa050524
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Genovese MC, Becker JC, Schiff M, Luggen M, Sherrer Y, Kremer J, et al. Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med. 2005;353(11):1114-23. (Pubitemid 41317434)
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Genovese, M.C.1
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Kremer, J.6
Birbara, C.7
Box, J.8
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Nuamah, I.10
Li, T.11
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Hagerty, D.T.13
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16
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84878673922
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An increasing proportion of patients achieve a low disease activity state or remission when switched from infliximab to abatacept regardless of initial infliximab treatment response: results from the ATTEST trial. Poster 1659 (392)
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Schiff M, Keiserman MW, Moniz Reed D, Le Bars M, Becker J-C, Zhao C, et al. An increasing proportion of patients achieve a low disease activity state or remission when switched from infliximab to abatacept regardless of initial infliximab treatment response: results from the ATTEST trial. Poster 1659 (392), ACR/ARHP Annual Scientific Meeting, October 16-21, 2009.
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ACR/ARHP Annual Scientific Meeting, October 16-21, 2009
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Schiff, M.1
Keiserman, M.W.2
Moniz Reed, D.3
Le Bars, M.4
Becker, J.-C.5
Zhao, C.6
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17
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70449709528
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The 6-month safety and efficacy of abatacept in patients with rheumatoid arthritis who underwent a washout after anti-tumour necrosis factor therapy or were directly switched to abatacept: The ARRIVE trial
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Schiff M, Pritchard C, Huffstutter JE, Rodriguez-Valverde V, Durez P, Zhou X, et al. The 6-month safety and efficacy of abatacept in patients with rheumatoid arthritis who underwent a washout after anti-tumour necrosis factor therapy or were directly switched to abatacept: the ARRIVE trial. Ann Rheum Dis. 2009;68(11):1708-14.
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Ann Rheum Dis
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Schiff, M.1
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Rodriguez-Valverde, V.4
Durez, P.5
Zhou, X.6
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18
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84878673771
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Time course of improvement in ACR core components in patients with early rheumatoid arthritis treated with abatacept plus methotrexate. Poster FRI0201
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Durez P, Bathon J, Becker JC, Covucci A, Moniz Reed D, Westhovens R. Time course of improvement in ACR core components in patients with early rheumatoid arthritis treated with abatacept plus methotrexate. Poster FRI0201, EULAR Annual Congress, June 16-19, 2010.
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EULAR Annual Congress, June 16-19, 2010
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Durez, P.1
Bathon, J.2
Becker, J.C.3
Covucci, A.4
Moniz Reed, D.5
Westhovens, R.6
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19
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84878671067
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Early improvements in disease activity with abatacept continue to increase or are maintained over time in methotrexate-naïve patients with early rheumatoid arthritis and poor prognostic factors. Poster SAT0109.
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Westhovens R, Moniz Reed D, Becker J-C, Vratsanos G, Yazici Y. Early improvements in disease activity with abatacept continue to increase or are maintained over time in methotrexate-naïve patients with early rheumatoid arthritis and poor prognostic factors. Poster SAT0109. EULAR Congress, 10-13 June, 2009.
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EULAR Congress, 10-13 June, 2009
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Westhovens, R.1
Moniz Reed, D.2
Becker, J.-C.3
Vratsanos, G.4
Yazici, Y.5
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20
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84878673261
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Disease remission, radiographic non-progression and normalization of function achieved at year 1 are sustained long-term in a majority of patients: 5-year outcomes with abatacept in biologic-naïve patients. Poster 1657 (390)
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Westhovens R, Dougados M, Hall S, Moniz Reed D, Becker J-C, Teng J, et al. Disease remission, radiographic non-progression and normalization of function achieved at year 1 are sustained long-term in a majority of patients: 5-year outcomes with abatacept in biologic-naïve patients. Poster 1657 (390). ACR/ARHP Annual Scientific Meeting, October 16-21, 2009.
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ACR/ARHP Annual Scientific Meeting, October 16-21, 2009
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Westhovens, R.1
Dougados, M.2
Hall, S.3
Moniz Reed, D.4
Becker, J.-C.5
Teng, J.6
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21
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84878673485
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Long-term safety of abatacept: integrated analysis of clinical program data of up to 7 years of treatment. Poster 390
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Hochberg MH, Westhovens R, Aranda R, Kelly S, Khan N, Qi K, et al. Long-term safety of abatacept: integrated analysis of clinical program data of up to 7 years of treatment. Poster 390, ACR/ARHP Annual Scientific Meeting, November 7-11, 2010.
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ACR/ARHP Annual Scientific Meeting, November 7-11, 2010
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Hochberg, M.H.1
Westhovens, R.2
Aranda, R.3
Kelly, S.4
Khan, N.5
Qi, K.6
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22
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79953018875
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Adverse effects of biologics: A network meta-analysis and Cochrane overview
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Singh JA, Wells GA, Christensen R, Tanjong Ghogomu E, Maxwell L, MacDonald JK, et al. Adverse effects of biologics: a network meta-analysis and Cochrane overview (Review). The Cochrane Library. 2011, Issue 2.
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Singh, J.A.1
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Maxwell, L.5
MacDonald, J.K.6
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23
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84878674872
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Serious infections and malignancies during long-term exposure to abatacept. Poster SAT0163
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Smitten A, Westhovens R, Hochberg M, Torbeyns A, Becker J-C, Aranda R. Serious infections and malignancies during long-term exposure to abatacept. Poster SAT0163, EULAR Annual Congress, June 16-19, 2010.
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EULAR Annual Congress, June 16-19, 2010
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Smitten, A.1
Westhovens, R.2
Hochberg, M.3
Torbeyns, A.4
Becker, J.-C.5
Aranda, R.6
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24
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33846853779
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Selective costimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: A randomised clinical trial
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DOI 10.1136/ard.2006.055111
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Weinblatt M, Schiff M, Goldman A, Kremer J, Luggen M, Li T, et al. Selective costimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: a randomised clinical trial. Ann Rheum Dis. 2007;66:228-34. (Pubitemid 46226059)
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Chen, D.7
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25
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34247860881
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Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: A randomized, open-label, parallel group study in healthy subjects
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Tay L, Leon F, Vratsanos G, Raymond R, Corbo M. Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects. Arthritis Research & Therapy. 2007;9:R38.
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Tay, L.1
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26
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84878675305
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Response to influenza vaccine in rheumatoid arthritis patients with an inadequate response to anti-TNF therapy treated with abatacept in the ARRIVE trial. Poster FRI 943/175
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Schiff M, Saewert M, Bahrt K, Genovese MC. Response to influenza vaccine in rheumatoid arthritis patients with an inadequate response to anti-TNF therapy treated with abatacept in the ARRIVE trial. Poster FRI 943/175, ACR Congress, November 6-11, 2007.
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ACR Congress, November 6-11, 2007
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Schiff, M.1
Saewert, M.2
Bahrt, K.3
Genovese, M.C.4
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27
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84863496536
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Abatacept in association with traditional DMARDS severely impairs humoral response to pandemic A H1N1 influenza vaccination in rheumatoid arthritis patients
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Abstract FRI0342
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Ribeiro A, Guedes L, Moraes J, Saad C, Calich A, Aikawa N, et al. Abatacept in association with traditional DMARDS severely impairs humoral response to pandemic A H1N1 influenza vaccination in rheumatoid arthritis patients. Ann Rheum Dis. 2011;70(Suppl3):458. Abstract FRI0342.
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Ribeiro, A.1
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Aikawa, N.6
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28
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84878670630
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Response to pneumococcal vaccine in rheumatoid arthritis patients with an inadequate response to anti-TNF therapy treated with abatacept in the ARRIVE trial. Poster SAT0029
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Schiff M, Kaell A, Tay L, Vratsanos G, Bahrt K. Response to pneumococcal vaccine in rheumatoid arthritis patients with an inadequate response to anti-TNF therapy treated with abatacept in the ARRIVE trial. Poster SAT0029, EULAR, June 13-16, 2007.
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Schiff, M.1
Kaell, A.2
Tay, L.3
Vratsanos, G.4
Bahrt, K.5
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29
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84878670630
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Incidence of anti-nuclear and anti-DNA antibody seropositivity, and immunogenicity, in patients with rheumatoid arthritis treated with abatacept or infliximab. Poster SAT0030
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Schiff M, Keiserman M, Codding C, Songcharoen S, Berman A, Nayiager S, et al. Incidence of anti-nuclear and anti-DNA antibody seropositivity, and immunogenicity, in patients with rheumatoid arthritis treated with abatacept or infliximab. Poster SAT0030, EULAR, June 13-16, 2007.
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EULAR, June 13-16, 2007
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Schiff, M.1
Keiserman, M.2
Codding, C.3
Songcharoen, S.4
Berman, A.5
Nayiager, S.6
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30
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80052057359
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Biologics in rheumatoid arthritis (RA) - Recommendations for Swiss practice
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