-
2
-
-
77953487867
-
Alterations on peripheral blood b-cell subpopulations in very early arthritis patients
-
Moura RA, Weinmann P, Pereira PA et al (2010) Alterations on peripheral blood B-cell subpopulations in very early arthritis patients. Rheumatology (Oxford) 49:1082-1092
-
(2010)
Rheumatology (Oxford
, vol.49
, pp. 1082-1092
-
-
Moura, R.A.1
Weinmann, P.2
Pereira, P.A.3
-
3
-
-
78751692218
-
Cytokine pattern in very early rheumatoid arthritis favours b-cell activation and survival
-
Moura RA, Cascao R, Perpetuo I et al (2011) Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival. Rheumatology (Oxford) 50:278-282
-
(2011)
Rheumatology (Oxford
, vol.50
, pp. 278-282
-
-
Moura, R.A.1
Cascao, R.2
Perpetuo, I.3
-
4
-
-
77958006636
-
Identification of a cytokine network sustaining neutrophil and th17 activation in untreated early rheumatoid arthritis
-
Cascao R, Moura RA, Perpetuo I et al (2010) Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis. Arthritis Res Ther 12:R196
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Cascao, R.1
Moura, R.A.2
Perpetuo, I.3
-
5
-
-
77956900662
-
B-cell-Activating factor receptor expression on naive and memory b cells: Relationship with relapse in patients with rheumatoid arthritis following b-cell depletion therapy
-
de la Torre I, Moura RA, Leandro MJ, Edwards J, Cambridge G (2010) B-cell-Activating factor receptor expression on naive and memory B cells: relationship with relapse in patients with rheumatoid arthritis following B-cell depletion therapy. Ann Rheum Dis 69:2181-2188
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 2181-2188
-
-
De La Torre, I.1
Moura, R.A.2
Leandro, M.J.3
Edwards, J.4
Cambridge, G.5
-
6
-
-
84979107869
-
On the occurrence of a factor in human serum activating the specific agglutination of sheep red corpuscles
-
Waaler E (1940) On the occurrence of a factor in human serum activating the specific agglutination of sheep red corpuscles. Acta Pathol Microbiol Scand 17:172-188
-
(1940)
Acta Pathol Microbiol Scand
, vol.17
, pp. 172-188
-
-
Waaler, E.1
-
7
-
-
0036745063
-
Epitope-specific recognition of type ii collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse
-
Burkhardt H, Koller T, Engstrom A et al (2002) Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse. Arthritis Rheum 46:2339-2348
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2339-2348
-
-
Burkhardt, H.1
Koller, T.2
Engstrom, A.3
-
8
-
-
17644415770
-
Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis
-
DOI 10.1136/ard.2004.025502
-
Schaller M, Stohl W, Tan SM, Benoit VM, Hilbert DM, Ditzel HJ (2005) Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis. Ann Rheum Dis 64:743-749 (Pubitemid 40559302)
-
(2005)
Annals of the Rheumatic Diseases
, vol.64
, Issue.5
, pp. 743-749
-
-
Schaller, M.1
Stohl, W.2
Tan, S.M.3
Benoit, V.M.4
Hilbert, D.M.5
Ditzel, H.J.6
-
9
-
-
0027516539
-
Autoantibody to the nuclear antigen RA33: A marker for early rheumatoid arthritis
-
Hassfeld W, Steiner G, Graninger W,Witzmann G, Schweitzer H, Smolen JS (1993) Autoantibody to the nuclear antigen RA33: a marker for early rheumatoid arthritis. Br J Rheumatol 32:199-203 (Pubitemid 23089981)
-
(1993)
British Journal of Rheumatology
, vol.32
, Issue.3
, pp. 199-203
-
-
Hassfeld, W.1
Steiner, G.2
Graininger, W.3
Witzmann, G.4
Schweitzer, H.5
Smolen, J.S.6
-
10
-
-
0031974911
-
Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
-
Schellekens GA, de Jong BA, van den Hoogen FH, van de Putte LB, van Venrooij WJ (1998) Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritisspecific autoantibodies. J Clin Invest 101:273-281 (Pubitemid 28058927)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.1
, pp. 273-281
-
-
Schellekens, G.A.1
De Jong, B.A.W.2
Van Den Hoogen, F.H.J.3
Van De Putte, L.B.A.4
Van Venrooij, W.J.5
-
11
-
-
77957002181
-
Development of proteoglycan-induced arthritis depends on t cell-supported autoantibody production, but does not involve significant influx of t cells into the joints
-
Angyal A, Egelston C, Kobezda T et al (2010) Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints. Arthritis Res Ther 12:R44
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Angyal, A.1
Egelston, C.2
Kobezda, T.3
-
12
-
-
0021796110
-
IgG and IgM rheumatoid factor synthesis in rheumatoid synovial membrane cell cultures
-
DOI 10.1002/art.1780280704
-
Wernick RM, Lipsky PE, Marban-Arcos E, Maliakkal JJ, Edelbaum D, Ziff M (1985) IgG and IgM rheumatoid factor synthesis in rheumatoid synovial membrane cell cultures. Arthritis Rheum 28:742-752 (Pubitemid 15027327)
-
(1985)
Arthritis and Rheumatism
, vol.28
, Issue.7
, pp. 742-752
-
-
Wernick, R.M.1
Lipsky, P.E.2
Marban-Arcos, E.3
-
13
-
-
0031903045
-
Rheumatoid arthritis: The predictable effect of small immune complexes in which antibody is also antigen
-
Edwards JC, Cambridge G (1998) Rheumatoid arthritis: the predictable effect of small immune complexes in which antibody is also antigen. Br J Rheumatol 37:126-130
-
(1998)
Br J Rheumatol
, vol.37
, pp. 126-130
-
-
Edwards, J.C.1
Cambridge, G.2
-
14
-
-
0031712994
-
Correlation of serum IgA rheumatoid factor levels with disease severity in rheumatoid arthritis
-
DOI 10.1080/030097498442352
-
Pai S, Pai L, Birkenfeldt R (1998) Correlation of serum IgA rheumatoid factor levels with disease severity in rheumatoid arthritis. Scand J Rheumatol 27:252-256 (Pubitemid 28416980)
-
(1998)
Scandinavian Journal of Rheumatology
, vol.27
, Issue.4
, pp. 252-256
-
-
Pai, S.1
Pai, L.2
Birkenfeldt, R.3
-
16
-
-
27744497998
-
Autoantibody profiling as early diagnostic and prognostic tool for rheumatoid arthritis
-
DOI 10.1136/ard.2005.035691
-
Nell VP, Machold KP, Stamm TA et al (2005) Autoantibody profiling as early diagnostic and prognostic tool for rheumatoid arthritis. Ann Rheum Dis 64:1731-1736 (Pubitemid 41667147)
-
(2005)
Annals of the Rheumatic Diseases
, vol.64
, Issue.12
, pp. 1731-1736
-
-
Nell, V.P.K.1
Machold, K.P.2
Stamm, T.A.3
Eberl, G.4
Heinzl, H.5
Uffmann, M.6
Smolen, J.S.7
Steiner, G.8
-
17
-
-
0031039486
-
Differences in mutational patterns between rheumatoid factors in health and disease are related to variable heavy chain family and germ-line gene usage
-
DOI 10.1002/eji.1830270323
-
Borretzen M, Chapman C, Natvig JB, Thompson KM (1997) Differences in mutational patterns between rheumatoid factors in health and disease are related to variable heavy chain family and germ-line gene usage. Eur J Immunol 27:735-741 (Pubitemid 27110587)
-
(1997)
European Journal of Immunology
, vol.27
, Issue.3
, pp. 735-741
-
-
Borretzen, M.1
Chapman, C.2
Natvig, J.B.3
Thompson, K.M.4
-
18
-
-
0028107057
-
Variable region gene usage of human monoclonal rheumatoid factors derived from healthy donors following immunization
-
DOI 10.1002/eji.1830240808
-
Thompson KM, Randen I, Borretzen M, Forre O, Natvig JB (1994) Variable region gene usage of human monoclonal rheumatoid factors derived from healthy donors following immunization. Eur J Immunol 24:1771-1778 (Pubitemid 24237545)
-
(1994)
European Journal of Immunology
, vol.24
, Issue.8
, pp. 1771-1778
-
-
Thompson, K.M.1
Randen, I.2
Borretzen, M.3
Forre, O.4
Natvig, J.B.5
-
19
-
-
0029569133
-
Raised IgA rheumatoid factor (RF) but not IgM RF or IgG RF is associated with extra-articular manifestations in rheumatoid arthritis
-
Jonsson T, Arinbjarnarson S, Thorsteinsson J et al (1995) Raised IgA rheumatoid factor (RF) but not IgM RF or IgG RF is associated with extra-Articular manifestations in rheumatoid arthritis. Scand J Rheumatol 24:372-375 (Pubitemid 26041938)
-
(1995)
Scandinavian Journal of Rheumatology
, vol.24
, Issue.6
, pp. 372-375
-
-
Jonsson, T.1
Arinbjarnarson, S.2
Thorsteinsson, J.3
Steinsson, K.4
Geirsson, A.J.5
Jonsson, H.6
Valdimarsson, H.7
-
20
-
-
0022413324
-
IgG rheumatoid factors and self-association of these antibodies
-
Mannik M, Nardella FA (1985) IgG rheumatoid factors and selfassociation of these antibodies. Clin Rheum Dis 11:551-572 (Pubitemid 16238187)
-
(1985)
Clinics in Rheumatic Diseases
, vol.11
, Issue.3
, pp. 551-572
-
-
Mannik, M.1
Nardella, F.A.2
-
21
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324 (Pubitemid 18091653)
-
(1988)
Arthritis and Rheumatism
, vol.31
, Issue.3
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
McShane, D.J.4
Fries, J.F.5
Cooper, N.S.6
Healey, L.A.7
Kaplan, S.R.8
Liang, M.H.9
Luthra, H.S.10
Medsger Jr., T.A.11
Mitchell, D.M.12
Neustadt, D.H.13
Pinals, R.S.14
Schaller, J.G.15
Sharp, J.T.16
Wilder, R.L.17
Hunder, G.G.18
-
22
-
-
77956055481
-
2010 Rheumatoid arthritis classification criteria: An american college of rheumatology/european league against rheumatism collaborative initiative
-
Aletaha D, Neogi T, Silman AJ et al (2010) 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 62:2569-2581
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2569-2581
-
-
Aletaha, D.1
Neogi, T.2
Silman, A.J.3
-
23
-
-
0034091322
-
The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide
-
DOI 10.1002/1529-0131(200001)43:1<155::AID-ANR20>3.0.CO;2-3
-
Schellekens GA, Visser H, de Jong BA et al (2000) The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum 43:155-163 (Pubitemid 30368225)
-
(2000)
Arthritis and Rheumatism
, vol.43
, Issue.1
, pp. 155-163
-
-
Schellekens, G.A.1
Visser, H.2
De Jong, B.A.W.3
Van Den Hoogen, F.H.J.4
Hazes, J.M.W.5
Breedveld, F.C.6
Van Venrooij, W.J.7
-
24
-
-
0032960781
-
The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues
-
Girbal-Neuhauser E, Durieux JJ, Arnaud M et al (1999) The epitopes targeted by the rheumatoid arthritis-Associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues. J Immunol 162:585-594 (Pubitemid 29018970)
-
(1999)
Journal of Immunology
, vol.162
, Issue.1
, pp. 585-594
-
-
Girbal-Neuhauser, E.1
Durieux, J.-J.2
Arnaud, M.3
Dalbon, P.4
Sebbag, M.5
Vincent, C.6
Simon, M.7
Senshu, T.8
Masson-Bessiere, C.9
Jolivet-Reynaud, C.10
Jolivet, M.11
Serre, G.12
-
25
-
-
0035147119
-
Secretion of anti-citrulline-containing peptide antibody by B lymphocytes in rheumatoid arthritis
-
DOI 10.1002/1529-0131(200101)44:1<41::AID-ANR6>3.0.CO;2-0
-
Reparon-Schuijt CC, van Esch WJ, van Kooten C et al (2001) Secretion of anti-citrulline-containing peptide antibody by B lymphocytes in rheumatoid arthritis. Arthritis Rheum 44:41-47 (Pubitemid 32113116)
-
(2001)
Arthritis and Rheumatism
, vol.44
, Issue.1
, pp. 41-47
-
-
Reparon-Schuijt, C.C.1
Van Esch, W.J.E.2
Van Kooten, C.3
Schellekens, G.A.4
De Jong, B.A.W.5
Van Venrooij, W.J.6
Breedveld, F.C.7
Verweij, C.L.8
-
26
-
-
0242720407
-
PAD, a growing family of citrullinating enzymes: Genes, features and involvement in disease
-
DOI 10.1002/bies.10357
-
Vossenaar ER, Zendman AJ, van Venrooij WJ, Pruijn GJ (2003) PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 25:1106-1118 (Pubitemid 37411770)
-
(2003)
BioEssays
, vol.25
, Issue.11
, pp. 1106-1118
-
-
Vossenaar, E.R.1
Zendman, A.J.W.2
Van Venrooij, W.J.3
Pruijn, G.J.M.4
-
27
-
-
77950238310
-
Autoantibodies in rheumatoid arthritis: Rheumatoid factors and anticitrullinated protein antibodies
-
Song YW, Kang EH (2010) Autoantibodies in rheumatoid arthritis: rheumatoid factors and anticitrullinated protein antibodies. QJM 103:139-146
-
(2010)
QJM
, vol.103
, pp. 139-146
-
-
Song, Y.W.1
Kang, E.H.2
-
28
-
-
0035869593
-
The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the α-and β-chains of fibrin
-
Masson-Bessiere C, Sebbag M, Girbal-Neuhauser E et al (2001) The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alphaand beta-chains of fibrin. J Immunol 166:4177-4184 (Pubitemid 32224951)
-
(2001)
Journal of Immunology
, vol.166
, Issue.6
, pp. 4177-4184
-
-
Masson-Bessiere, C.1
Sebbag, M.2
Girbal-Neuhauser, E.3
Nogueira, L.4
Vincent, C.5
Senshu, T.6
Serre, G.7
-
29
-
-
51249085423
-
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis
-
Zhao X, Okeke NL, Sharpe O et al (2008) Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. Arthritis Res Ther 10:R94
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Zhao, X.1
Okeke, N.L.2
Sharpe, O.3
-
30
-
-
27844575688
-
Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis
-
van der Helm-van Mil AH, Verpoort KN, Breedveld FC, Toes RE, Huizinga TW (2005) Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis. Arthritis Res Ther 7:R949-958
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Van Der Helm-Van Mil, A.H.1
Verpoort, K.N.2
Breedveld, F.C.3
Toes, R.E.4
Huizinga, T.W.5
-
31
-
-
63049101247
-
Structure and pathogenicity of antibodies specific for citrullinated collagen type ii in experimental arthritis
-
Uysal H, Bockermann R, Nandakumar KS et al (2009) Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis. J Exp Med 206:449-462
-
(2009)
J Exp Med
, vol.206
, pp. 449-462
-
-
Uysal, H.1
Bockermann, R.2
Nandakumar, K.S.3
-
32
-
-
68049104242
-
Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis and rheumatoid arthritis
-
van der Linden MP, van derWoude D, Ioan-Facsinay A et al (2009) Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis and rheumatoid arthritis. Arthritis Rheum 60:2232-2241
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2232-2241
-
-
Van Der Linden, M.P.1
Van Der Woude, D.2
Ioan-Facsinay, A.3
-
33
-
-
38149092561
-
Differences in synovial tissue infiltrates between anti-cyclic citrullinated peptide-positive rheumatoid arthritis and anti-cyclic citrullinated peptide-negative rheumatoid arthritis
-
van Oosterhout M, Bajema I, Levarht EW, Toes RE, Huizinga TW, van Laar JM (2008) Differences in synovial tissue infiltrates between anti-cyclic citrullinated peptide-positive rheumatoid arthritis and anti-cyclic citrullinated peptide-negative rheumatoid arthritis. Arthritis Rheum 58:53-60
-
(2008)
Arthritis Rheum
, vol.58
, pp. 53-60
-
-
Van Oosterhout, M.1
Bajema, I.2
Levarht, E.W.3
Toes, R.E.4
Huizinga, T.W.5
Van Laar, J.M.6
-
34
-
-
38749113412
-
High anti-cyclic citrullinated peptide levels and an algorithm of four variables predict radiographic progression in patients with rheumatoid arthritis: Results from a 10-year longitudinal study
-
DOI 10.1136/ard.2006.068247
-
Syversen SW, Gaarder PI, Goll GL et al (2008) High anti-cyclic citrullinated peptide levels and an algorithm of four variables predict radiographic progression in patients with rheumatoid arthritis: results from a 10-year longitudinal study. Ann Rheum Dis 67:212-217 (Pubitemid 351183310)
-
(2008)
Annals of the Rheumatic Diseases
, vol.67
, Issue.2
, pp. 212-217
-
-
Syversen, S.W.1
Gaarder, P.I.2
Goll, G.L.3
Odegard, S.4
Haavardsholm, E.A.5
Mowinckel, P.6
Van Der Heijde, D.7
Landewe, R.8
Kvien, T.K.9
-
35
-
-
0034606359
-
Follicular b helper t cells express cxc chemokine receptor 5, localize to b cell follicles, and support immunoglobulin production
-
Breitfeld D, Ohl L, Kremmer E et al (2000) Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med 192:1545-1552
-
(2000)
J Exp Med
, vol.192
, pp. 1545-1552
-
-
Breitfeld, D.1
Ohl, L.2
Kremmer, E.3
-
36
-
-
0030070295
-
Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis
-
DOI 10.1073/pnas.93.1.221
-
Schroder AE, Greiner A, Seyfert C, Berek C (1996) Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis. Proc Natl Acad Sci U S A 93:221-225 (Pubitemid 26038131)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.1
, pp. 221-225
-
-
Schroder, A.E.1
Greiner, A.2
Seyfert, C.3
Berek, C.4
-
37
-
-
0035879123
-
Lymphoid neogenesis in rheumatoid synovitis
-
Takemura S, Braun A, Crowson C et al (2001) Lymphoid neogenesis in rheumatoid synovitis. J Immunol 167:1072-1080 (Pubitemid 32660867)
-
(2001)
Journal of Immunology
, vol.167
, Issue.2
, pp. 1072-1080
-
-
Takemura, S.1
Braun, A.2
Crowson, C.3
Kurtin, P.J.4
Cofield, R.H.5
O'Fallon, W.M.6
Goronzy, J.J.7
Weyand, C.M.8
-
38
-
-
59249104722
-
Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium
-
Humby F, Bombardieri M, Manzo A et al (2009) Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium. PLoS Med 6:e1
-
(2009)
PLoS Med
, vol.6
-
-
Humby, F.1
Bombardieri, M.2
Manzo, A.3
-
39
-
-
0033818367
-
Histology of the synovial tissue: Value of semiquantitative analysis for the prediction of joint erosions in rheumatoid arthritis
-
Fonseca JE, Canhao H, Resende C et al (2000) Histology of the synovial tissue: value of semiquantitative analysis for the prediction of joint erosions in rheumatoid arthritis. Clin Exp Rheumatol 18:559-564
-
(2000)
Clin Exp Rheumatol
, vol.18
, pp. 559-564
-
-
Fonseca, J.E.1
Canhao, H.2
Resende, C.3
-
40
-
-
55849110806
-
Mature antigenexperienced t helper cells synthesize and secrete the b cell chemoattractant cxcl13 in the inflammatory environment of the rheumatoid joint
-
Manzo A, Vitolo B, Humby F et al (2008) Mature antigenexperienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint. Arthritis Rheum 58:3377-3387
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3377-3387
-
-
Manzo, A.1
Vitolo, B.2
Humby, F.3
-
41
-
-
34247181323
-
Up-regulation of stromal cell-derived factor 1 (cxcl12) production in rheumatoid synovial fibroblasts through interactions with t lymphocytes: Role of interleukin-17 and cd40l-cd40 interaction
-
Kim KW, Cho ML, Kim HR et al (2007) Up-regulation of stromal cell-derived factor 1 (CXCL12) production in rheumatoid synovial fibroblasts through interactions with T lymphocytes: role of interleukin-17 and CD40L-CD40 interaction. Arthritis Rheum 56:1076-1086
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1076-1086
-
-
Kim, K.W.1
Cho, M.L.2
Kim, H.R.3
-
42
-
-
0032127288
-
Lymph node genesis is induced by signaling through the lymphotoxin β receptor
-
DOI 10.1016/S1074-7613(00)80589-0
-
Rennert PD, James D, Mackay F, Browning JL, Hochman PS (1998) Lymph node genesis is induced by signaling through the lymphotoxin beta receptor. Immunity 9:71-79 (Pubitemid 28361296)
-
(1998)
Immunity
, vol.9
, Issue.1
, pp. 71-79
-
-
Rennert, P.D.1
James, D.2
Mackay, F.3
Browning, J.L.4
Hochman, P.S.5
-
43
-
-
0034972257
-
Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
-
DOI 10.1002/1529-0131(200106)44:6<1313::AID-ART223>3.0.CO;2-S
-
Cheema GS, Roschke V, Hilbert DM, Stohl W (2001) Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 44:1313-1319 (Pubitemid 32537529)
-
(2001)
Arthritis and Rheumatism
, vol.44
, Issue.6
, pp. 1313-1319
-
-
Cheema, G.S.1
Roschke, V.2
Hilbert, D.M.3
Stohl, W.4
-
44
-
-
41949133387
-
Baff enhances chemotaxis of primary human b cells: A particular synergy between baff and cxcl13 on memory b cells
-
Badr G, Borhis G, Lefevre EA et al (2008) BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells. Blood 111:2744-2754
-
(2008)
Blood
, vol.111
, pp. 2744-2754
-
-
Badr, G.1
Borhis, G.2
Lefevre, E.A.3
-
45
-
-
0023942493
-
Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
-
Houssiau FA, Devogelaer JP, Van Damme J, de Deuxchaisnes CN, Van Snick J (1988) Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis Rheum 31:784-788
-
(1988)
Arthritis Rheum
, vol.31
, pp. 784-788
-
-
Houssiau, F.A.1
Devogelaer, J.P.2
Van Damme, J.3
De Deuxchaisnes, C.N.4
Van Snick, J.5
-
46
-
-
67349104400
-
Interleukin-6 as a key player in systemic inflammation and joint destruction
-
Fonseca JE, Santos MJ, Canhao H, Choy E (2009) Interleukin-6 as a key player in systemic inflammation and joint destruction. Autoimmun Rev 8:538-542
-
(2009)
Autoimmun Rev
, vol.8
, pp. 538-542
-
-
Fonseca, J.E.1
Santos, M.J.2
Canhao, H.3
Choy, E.4
-
47
-
-
29144519767
-
IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells
-
Ettinger R, Sims GP, Fairhurst AM et al (2005) IL-21 induces differentiation of human naive and memory B cells into antibodysecreting plasma cells. J Immunol 175:7867-7879 (Pubitemid 41798347)
-
(2005)
Journal of Immunology
, vol.175
, Issue.12
, pp. 7867-7879
-
-
Ettinger, R.1
Sims, G.P.2
Fairhurst, A.-M.3
Robbins, R.4
Da Silva, Y.S.5
Spolski, R.6
Leonard, W.J.7
Lipsky, P.E.8
-
48
-
-
84871657147
-
Th17 cells can provide b cell help in autoantibody induced arthritis
-
Hickman-Brecks, C. L., Racz, J. L., Meyer, D. M., Labranche, T. P., Allen, P. M. (2010), Th17 cells can provide B cell help in autoantibody induced arthritis. J Autoimmun
-
(2010)
J Autoimmun
-
-
Hickman-Brecks, C.L.1
Racz, J.L.2
Meyer, D.M.3
Labranche, T.P.4
Allen, P.M.5
-
49
-
-
78049354525
-
B and t lymphocyte attenuator suppresses il-21 production from follicular th cells and subsequent humoral immune responses
-
Kashiwakuma D, Suto A, Hiramatsu Y et al (2010) B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses. J Immunol 185:2730-2736
-
(2010)
J Immunol
, vol.185
, pp. 2730-2736
-
-
Kashiwakuma, D.1
Suto, A.2
Hiramatsu, Y.3
-
50
-
-
0021956416
-
Antigen-specific interaction between T and B cells
-
DOI 10.1038/314537a0
-
Lanzavecchia A (1985) Antigen-specific interaction between T and B cells. Nature 314:537-539 (Pubitemid 15124262)
-
(1985)
Nature
, vol.314
, Issue.6011
, pp. 537-539
-
-
Lanzavecchia, A.1
-
51
-
-
0035214305
-
Role of B cells as antigen-presenting cells in vivo revisited: Antigen-specific B cells are essential for T cell expansion in lymph nodes and for systemic T cell responses to low antigen concentrations
-
Rivera A, Chen CC, Ron N, Dougherty JP, Ron Y (2001) Role of B cells as antigen-presenting cells in vivo revisited: antigenspecific B cells are essential for T cell expansion in lymph nodes and for systemic T cell responses to low antigen concentrations. Int Immunol 13:1583-1593 (Pubitemid 33133885)
-
(2001)
International Immunology
, vol.13
, Issue.12
, pp. 1583-1593
-
-
Rivera, A.1
Chen, C.-C.2
Ron, N.3
Dougherty, J.P.4
Ron, Y.5
-
52
-
-
0026031973
-
Efficient and selective presentation of antigen-Antibody complexes by rheumatoid factor b cells
-
Roosnek E, Lanzavecchia A (1991) Efficient and selective presentation of antigen-Antibody complexes by rheumatoid factor B cells. J Exp Med 173:487-489
-
(1991)
J Exp Med
, vol.173
, pp. 487-489
-
-
Roosnek, E.1
Lanzavecchia, A.2
-
53
-
-
0027514683
-
Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice
-
DOI 10.1084/jem.177.1.109
-
Tighe H, Chen PP, Tucker R et al (1993) Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice. J Exp Med 177:109-118 (Pubitemid 23008090)
-
(1993)
Journal of Experimental Medicine
, vol.177
, Issue.1
, pp. 109-118
-
-
Tighe, H.1
Chen, P.P.2
Tucker, R.3
Kipps, T.J.4
Roudier, J.5
Jirik, F.R.6
Carson, D.A.7
-
54
-
-
14844347864
-
Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis
-
O'Neill SK, Shlomchik MJ, Glant TT, Cao Y, Doodes PD, Finnegan A (2005) Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis. J Immunol 174:3781-3788 (Pubitemid 40354091)
-
(2005)
Journal of Immunology
, vol.174
, Issue.6
, pp. 3781-3788
-
-
O'Neill, S.K.1
Shlomchik, M.J.2
Glant, T.T.3
Cao, Y.4
Doodes, P.D.5
Finnegan, A.6
-
55
-
-
0035888030
-
T cell activation in rheumatoid synovium is B cell dependent
-
Takemura S, Klimiuk PA, Braun A, Goronzy JJ, Weyand CM (2001) T cell activation in rheumatoid synovium is B cell dependent. J Immunol 167:4710-4718 (Pubitemid 32954353)
-
(2001)
Journal of Immunology
, vol.167
, Issue.8
, pp. 4710-4718
-
-
Takemura, S.1
Klimiuk, P.A.2
Braun, A.3
Goronzy, J.J.4
Weyand, C.M.5
-
56
-
-
80555149788
-
B cell depletion enhances t regulatory cell activity essential in the suppression of arthritis
-
Hamel KM, Cao Y, Ashaye S et al (2011) B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis. J Immunol 187:4900-4906
-
(2011)
J Immunol
, vol.187
, pp. 4900-4906
-
-
Hamel, K.M.1
Cao, Y.2
Ashaye, S.3
-
57
-
-
77956413981
-
Modulation of il-17 and foxp3 expression in the prevention of autoimmune arthritis in mice
-
Duarte J, Agua-Doce A, Oliveira VG, Fonseca JE, Graca L (2010) Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice. PLoS One 5:e10558
-
(2010)
PLoS One
, vol.5
-
-
Duarte, J.1
Agua-Doce, A.2
Oliveira, V.G.3
Fonseca, J.E.4
Graca, L.5
-
58
-
-
27544490377
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
DOI 10.1038/ni1254, PII N1254
-
Harrington LE, Hatton RD,Mangan PR et al (2005) Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6:1123-1132 (Pubitemid 41541790)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
59
-
-
1042267236
-
Treatment with a Neutralizing Anti-Murine Interleukin-17 Antibody after the Onset of Collagen-Induced Arthritis Reduces Joint Inflammation, Cartilage Destruction, and Bone Erosion
-
DOI 10.1002/art.20001
-
Lubberts E, Koenders MI, Oppers-Walgreen B et al (2004) Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum 50:650-659 (Pubitemid 38198849)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.2
, pp. 650-659
-
-
Lubberts, E.1
Koenders, M.I.2
Oppers-Walgreen, B.3
Van Den Bersselaar, L.4
Coenen-De Roo, C.J.J.5
Joosten, L.A.B.6
Van Den Berg, W.B.7
-
60
-
-
0032939156
-
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
-
DOI 10.1002/1529-0131(199905)42:5<963::AID-ANR15>3.0.CO;2-E
-
Chabaud M, Durand JM, Buchs N et al (1999) Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 42:963-970 (Pubitemid 29215007)
-
(1999)
Arthritis and Rheumatism
, vol.42
, Issue.5
, pp. 963-970
-
-
Chabaud, M.1
Durand, J.M.2
Buchs, N.3
Fossiez, F.4
Page, G.5
Frappart, L.6
Miossec, P.7
-
61
-
-
38349178776
-
Interleukin 17-producing t helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune bxd2 mice
-
Hsu HC, Yang P, Wang J et al (2008) Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol 9:166-175
-
(2008)
Nat Immunol
, vol.9
, pp. 166-175
-
-
Hsu, H.C.1
Yang, P.2
Wang, J.3
-
62
-
-
77951910269
-
Il-17 activates the canonical nf-kappab signaling pathway in autoimmune b cells of bxd2 mice to upregulate the expression of regulators of g-protein signaling 16
-
Xie S, Li J, Wang JH et al (2010) IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16. J Immunol 184:2289-2296
-
(2010)
J Immunol
, vol.184
, pp. 2289-2296
-
-
Xie, S.1
Li, J.2
Wang, J.H.3
-
63
-
-
54449087291
-
Local baff gene silencing suppresses th17-cell generation and ameliorates autoimmune arthritis
-
Lai Kwan Lam Q, King Hung Ko O, Zheng BJ, Lu L (2008) Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis. Proc Natl Acad Sci U S A 105:14993-14998
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14993-14998
-
-
Lai Kwan Lam, Q.1
King Hung Ko, O.2
Zheng, B.J.3
Lu, L.4
-
64
-
-
77956273246
-
Proinflammatory t helper type 17 cells are effective b-cell helpers
-
Mitsdoerffer M, Lee Y, Jager A et al (2010) Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A 107:14292-14297
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14292-14297
-
-
Mitsdoerffer, M.1
Lee, Y.2
Jager, A.3
-
65
-
-
47949128751
-
B cell chemoattractant cxcl13 is preferentially expressed by human th17 cell clones
-
Takagi R, Higashi T, Hashimoto K et al (2008) B cell chemoattractant CXCL13 is preferentially expressed by human Th17 cell clones. J Immunol 181:186-189
-
(2008)
J Immunol
, vol.181
, pp. 186-189
-
-
Takagi, R.1
Higashi, T.2
Hashimoto, K.3
-
66
-
-
0030606310
-
Organ-specific disease provoked by systemic autoimmunity
-
DOI 10.1016/S0092-8674(00)81989-3
-
Kouskoff V, Korganow AS, Duchatelle V, Degott C, Benoist C, Mathis D (1996) Organ-specific disease provoked by systemic autoimmunity. Cell 87:811-822 (Pubitemid 26404281)
-
(1996)
Cell
, vol.87
, Issue.5
, pp. 811-822
-
-
Kouskoff, V.1
Korganow, A.-S.2
Duchatelle, V.3
Degott, C.4
Benoist, C.5
Mathis, D.6
-
67
-
-
0033118675
-
From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins
-
DOI 10.1016/S1074-7613(00)80045-X
-
Korganow AS, Ji H, Mangialaio S et al (1999) From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity 10:451-461 (Pubitemid 29205481)
-
(1999)
Immunity
, vol.10
, Issue.4
, pp. 451-461
-
-
Korganow, A.-S.1
Hong, J.2
Mangialaio, S.3
Duchatelle, V.4
Pelanda, R.5
Martin, T.6
Degott, C.7
Kikutani, H.8
Rajewsky, K.9
Pasquali, J.-L.10
Benoist, C.11
Mathis, D.12
-
68
-
-
77953913586
-
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via t helper 17 cells
-
Wu HJ, Ivanov II, Darce J et al (2010) Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 32:815-827
-
(2010)
Immunity
, vol.32
, pp. 815-827
-
-
Wu, H.J.1
Ivanov, I.I.2
Darce, J.3
-
69
-
-
77957678588
-
Monoclonal anti-cd8 therapy induces disease amelioration in the k/bxn mouse model of spontaneous chronic polyarthritis
-
Raposo BR, Rodrigues-Santos P, Carvalheiro H et al (2010) Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis. Arthritis Rheum 62:2953-2962
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2953-2962
-
-
Raposo, B.R.1
Rodrigues-Santos, P.2
Carvalheiro, H.3
-
70
-
-
0345414139
-
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
-
DOI 10.1038/nature02119
-
Sakaguchi N, Takahashi T, Hata H et al (2003) Altered thymic Tcell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice. Nature 426:454-460 (Pubitemid 37490133)
-
(2003)
Nature
, vol.426
, Issue.6965
, pp. 454-460
-
-
Sakaguchi, N.1
Takahashi, T.2
Hata, H.3
Nomura, T.4
Tagami, T.5
Yamazaki, S.6
Sakihama, T.7
Matsutani, T.8
Negishi, I.9
Nakatsuru, S.10
Sakaguchi, S.11
-
71
-
-
0034942508
-
Influence of CD4 or CD8 deficiency on collagen-induced arthritis
-
DOI 10.1046/j.1365-2567.2001.01257.x
-
Ehinger M, Vestberg M, Johansson AC, Johannesson M, Svensson A, Holmdahl R (2001) Influence of CD4 or CD8 deficiency on collagen-induced arthritis. Immunology 103:291-300 (Pubitemid 32631466)
-
(2001)
Immunology
, vol.103
, Issue.3
, pp. 291-300
-
-
Ehinger, M.1
Vestberg, M.2
Johansson, A.C.M.3
Johannesson, M.4
Svensson, A.5
Holmdahl, R.6
-
72
-
-
0031899715
-
B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)
-
DOI 10.1046/j.1365-2249.1998.00529.x
-
Svensson L, Jirholt J, Holmdahl R, Jansson L (1998) B celldeficient mice do not develop type II collagen-induced arthritis (CIA). Clin Exp Immunol 111:521-526 (Pubitemid 28160894)
-
(1998)
Clinical and Experimental Immunology
, vol.111
, Issue.3
, pp. 521-526
-
-
Svensson, L.1
Jirholt, J.2
Holmdahl, R.3
Jansson, L.4
-
73
-
-
80052648266
-
To b or not to b: Role of b cells in pathogenesis of arthritis in hla transgenic mice
-
Behrens M, Smart M, Luckey D, Luthra H, Taneja V (2011) To B or not to B: role of B cells in pathogenesis of arthritis in HLA transgenic mice. J Autoimmun 37:95-103
-
(2011)
J Autoimmun
, vol.37
, pp. 95-103
-
-
Behrens, M.1
Smart, M.2
Luckey, D.3
Luthra, H.4
Taneja, V.5
-
75
-
-
1842368507
-
IDEC-C2B8 (rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma
-
Maloney DG, Grillo-Lopez AJ, White CA et al (1997) IDECC2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma. Blood 90:2188-2195 (Pubitemid 27392702)
-
(1997)
Blood
, vol.90
, Issue.6
, pp. 2188-2195
-
-
Maloney, D.G.1
Grillo-Lopez, A.J.2
White, C.A.3
Bodkin, D.4
Schilder, R.J.5
Neidhart, J.A.6
Janakiraman, N.7
Foon, K.A.8
Liles, T.-M.9
Dallaire, B.K.10
Wey, K.11
Royston, I.12
Davis, T.13
Levy, R.14
-
76
-
-
0031785720
-
Use of rituximab, the new FDA-approved antibody
-
Leget GA, Czuczman MS (1998) Use of rituximab, the new FDA-Approved antibody. Curr Opin Oncol 10:548-551 (Pubitemid 28502249)
-
(1998)
Current Opinion in Oncology
, vol.10
, Issue.6
, pp. 548-551
-
-
Leget, G.A.1
Czuczman, M.S.2
-
77
-
-
0035093233
-
Sustained improvement in rheumatoid arthritis following a protocol designed to deplete b lymphocytes
-
Edwards JC, Cambridge G (2001) Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes. Rheumatology (Oxford) 40:205-211
-
(2001)
Rheumatology (Oxford
, vol.40
, pp. 205-211
-
-
Edwards, J.C.1
Cambridge, G.2
-
78
-
-
0036785351
-
Clinical outcome in 22 patients with rheumatoid arthritis treated with b lymphocyte depletion
-
Leandro MJ, Edwards JC, Cambridge G (2002) Clinical outcome in 22 patients with rheumatoid arthritis treated with B lymphocyte depletion. Ann Rheum Dis 61:883-888
-
(2002)
Ann Rheum Dis
, vol.61
, pp. 883-888
-
-
Leandro, M.J.1
Edwards, J.C.2
Cambridge, G.3
-
79
-
-
2942537697
-
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
-
DOI 10.1056/NEJMoa032534
-
Edwards JC, Szczepanski L, Szechinski J et al (2004) Efficacy of B-cell-Targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med 350:2572-2581 (Pubitemid 38758544)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.25
, pp. 2572-2581
-
-
Edwards, J.C.W.1
Szczepanski, L.2
Szechinski, J.3
Filipowicz-Sosnowska, A.4
Emery, P.5
Close, D.R.6
Stevens, R.M.7
Shaw, T.8
-
80
-
-
33646483031
-
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase iib randomized, double-blind, placebo-controlled, doseranging trial
-
Emery P, Fleischmann R, Filipowicz-Sosnowska A et al (2006) The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, doseranging trial. Arthritis Rheum 54:1390-1400
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1390-1400
-
-
Emery, P.1
Fleischmann, R.2
Filipowicz-Sosnowska, A.3
-
81
-
-
0033611472
-
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
-
DOI 10.1056/NEJM199901283400401
-
Weinblatt ME, Kremer JM, Bankhurst AD et al (1999) A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 340:253-259 (Pubitemid 29063266)
-
(1999)
New England Journal of Medicine
, vol.340
, Issue.4
, pp. 253-259
-
-
Weinblatt, M.E.1
Kremer, J.M.2
Bankhurst, A.D.3
Bulpitt, K.J.4
Fleischmann, R.M.5
Fox, R.I.6
Jackson, C.G.7
Lange, M.8
Burge, D.J.9
-
82
-
-
0034735842
-
Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study group
-
Lipsky PE, van der Heijde DM, St Clair EW et al (2000) Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med 343:1594-1602
-
(2000)
N Engl J Med
, vol.343
, pp. 1594-1602
-
-
Lipsky, P.E.1
Van Der Heijde, D.M.2
St Clair, E.W.3
-
83
-
-
0037231533
-
Adalimumab, a fully human anti-tumor necrosis factor α monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
-
DOI 10.1002/art.10697
-
Weinblatt ME, Keystone EC, Furst DE et al (2003) Adalimumab, a fully human anti-Tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum 48:35-45 (Pubitemid 36091645)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.1
, pp. 35-45
-
-
Weinblatt, M.E.1
Keystone, E.C.2
Furst, D.E.3
Moreland, L.W.4
Weisman, M.H.5
Birbara, C.A.6
Teoh, L.A.7
Fischkoff, S.A.8
Chartash, E.K.9
-
84
-
-
33746961890
-
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
-
DOI 10.1002/art.22025
-
Cohen SB, Emery P, Greenwald MW et al (2006) Rituximab for rheumatoid arthritis refractory to anti-Tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebocontrolled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum 54:2793-2806 (Pubitemid 44497758)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.9
, pp. 2793-2806
-
-
Cohen, S.B.1
Emery, P.2
Greenwald, M.W.3
Dougados, M.4
Furie, R.A.5
Genovese, M.C.6
Keystone, E.C.7
Loveless, J.E.8
Burmester, G.-R.9
Cravets, M.W.10
Hessey, E.W.11
Shaw, T.12
Totoritis, M.C.13
-
85
-
-
2542490265
-
B lymphocyte depletion therapy with rituximab in rheumatoid arthritis
-
DOI 10.1016/j.rdc.2004.01.006, PII S0889857X04000201
-
Edwards, J. C., Leandro, M. J., Cambridge, G. (2004), B lymphocyte depletion therapy with rituximab in rheumatoid arthritis. Rheum Dis Clin North Am. 30, 393-403, viii (Pubitemid 38692569)
-
(2004)
Rheumatic Disease Clinics of North America
, vol.30
, Issue.2
, pp. 393-403
-
-
Edwards, J.C.W.1
Leandro, M.J.2
Cambridge, G.3
-
86
-
-
45349102781
-
Anti-CD20 therapy in patients with rheumatoid arthritis: Predictors of response and b cell subset regeneration after repeated treatment
-
DOI 10.1002/art.23473
-
Roll P, Dorner T, Tony HP (2008) Anti-CD20 therapy in patients with rheumatoid arthritis: predictors of response and B cell subset regeneration after repeated treatment. Arthritis Rheum 58:1566-1575 (Pubitemid 351847509)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.6
, pp. 1566-1575
-
-
Roll, P.1
Dorner, T.2
Tony, H.-P.3
-
87
-
-
75649121049
-
Rheumatoid factor positivity rather than anti-ccp positivity, a lower disability and a lower number of anti-Tnf agents failed are associated with response to rituximab in rheumatoid arthritis
-
Quartuccio L, Fabris M, Salvin S et al (2009) Rheumatoid factor positivity rather than anti-CCP positivity, a lower disability and a lower number of anti-TNF agents failed are associated with response to rituximab in rheumatoid arthritis. Rheumatology (Oxford) 48:1557-1559
-
(2009)
Rheumatology (Oxford
, vol.48
, pp. 1557-1559
-
-
Quartuccio, L.1
Fabris, M.2
Salvin, S.3
-
88
-
-
76949095678
-
Response to rituximab and timeframe to relapse in rheumatoid arthritis patients: Association with b-cell markers
-
Pyrpasopoulou A, Douma S, Triantafyllou A et al (2010) Response to rituximab and timeframe to relapse in rheumatoid arthritis patients: association with B-cell markers. Mol Diagn Ther 14:43-48
-
(2010)
Mol Diagn Ther
, vol.14
, pp. 43-48
-
-
Pyrpasopoulou, A.1
Douma, S.2
Triantafyllou, A.3
-
89
-
-
0041571732
-
Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis
-
DOI 10.1002/art.11181
-
Cambridge G, Leandro MJ, Edwards JC et al (2003) Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis. Arthritis Rheum 48:2146-2154 (Pubitemid 36959194)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.8
, pp. 2146-2154
-
-
Cambridge, G.1
Leandro, M.J.2
Edwards, J.C.W.3
Ehrenstein, M.R.4
Salden, M.5
Bodman-Smith, M.6
Webster, A.D.B.7
-
90
-
-
33845596250
-
Bone marrow B-lineage cells in patients with rheumatoid arthritis following rituximab therapy
-
DOI 10.1093/rheumatology/kel148
-
Leandro MJ, Cooper N, Cambridge G, Ehrenstein MR, Edwards JC (2007) Bone marrow B-lineage cells in patients with rheumatoid arthritis following rituximab therapy. Rheumatology (Oxford) 46:29-36 (Pubitemid 44932780)
-
(2007)
Rheumatology
, vol.46
, Issue.1
, pp. 29-36
-
-
Leandro, M.J.1
Cooper, N.2
Cambridge, G.3
Ehrenstein, M.R.4
Edwards, J.C.W.5
-
91
-
-
37149010203
-
Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment
-
DOI 10.1002/art.22967
-
Teng YK, Levarht EW, Hashemi M e t a l (2007) Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment. Arthritis Rheum 56:3909-3918 (Pubitemid 350262317)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.12
, pp. 3909-3918
-
-
Teng, Y.K.O.1
Levarht, E.W.N.2
Hashemi, M.3
Bajema, I.M.4
Toes, R.E.M.5
Huizinga, T.W.J.6
Van Laar, J.M.7
-
92
-
-
33644914684
-
Circulating levels of b lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: Relationships with b cell depletion, circulating antibodies, and clinical relapse
-
Cambridge G, Stohl W, Leandro MJ, Migone TS, Hilbert DM, Edwards JC (2006) Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse. Arthritis Rheum 54:723-732
-
(2006)
Arthritis Rheum
, vol.54
, pp. 723-732
-
-
Cambridge, G.1
Stohl, W.2
Leandro, M.J.3
Migone, T.S.4
Hilbert, D.M.5
Edwards, J.C.6
-
93
-
-
0030666959
-
Suppressive role of B cells in chronic colitis of T cell receptor α mutant mice
-
DOI 10.1084/jem.186.10.1749
-
Mizoguchi A, Mizoguchi E, Smith RN, Preffer FI, Bhan AK (1997) Suppressive role of B cells in chronic colitis of T cell receptor alpha mutant mice. J Exp Med 186:1749-1756 (Pubitemid 27506287)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.10
, pp. 1749-1756
-
-
Mizoguchi, A.1
Mizoguchi, E.2
Smith, R.N.3
Preffer, F.I.4
Bhan, A.K.5
-
94
-
-
0036197923
-
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
-
DOI 10.1016/S1074-7613(02)00274-1
-
Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK (2002) Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16:219-230 (Pubitemid 34211962)
-
(2002)
Immunity
, vol.16
, Issue.2
, pp. 219-230
-
-
Mizoguchi, A.1
Mizoguchi, E.2
Takedatsu, H.3
Blumberg, R.S.4
Bhan, A.K.5
-
95
-
-
0037450740
-
Prevention of arthritis by interleukin 10-producing B cells
-
DOI 10.1084/jem.20021293
-
Mauri C, Gray D, Mushtaq N, Londei M (2003) Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197:489-501 (Pubitemid 36278604)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.4
, pp. 489-501
-
-
Mauri, C.1
Gray, D.2
Mushtaq, N.3
Londei, M.4
-
96
-
-
65449188259
-
Selective targeting of b cells with agonistic anti-cd40 is an efficacious strategy for the generation of induced regulatory t2-like b cells and for the suppression of lupus in mrl/lpr mice
-
Blair PA, Chavez-Rueda KA, Evans JG et al (2009) Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice. J Immunol 182:3492-3502
-
(2009)
J Immunol
, vol.182
, pp. 3492-3502
-
-
Blair, P.A.1
Chavez-Rueda, K.A.2
Evans, J.G.3
-
97
-
-
0036795531
-
B cells regulate autoimmunity by provision of IL-10
-
DOI 10.1038/ni833
-
Fillatreau S, Sweenie CH, McGeachy MJ, Gray D, Anderton SM (2002) B cells regulate autoimmunity by provision of IL-10. Nat Immunol 3:944-950 (Pubitemid 35154008)
-
(2002)
Nature Immunology
, vol.3
, Issue.10
, pp. 944-950
-
-
Fillatreau, S.1
Sweenie, C.H.2
McGeachy, M.J.3
Gray, D.4
Anderton, S.M.5
-
98
-
-
79955777196
-
Allergenspecific transforming growth factor-beta-producing cd19+ cd5+ regulatory b-cell (br3) responses in human late eczematous allergic reactions to cow's milk
-
Lee JH, Noh J, Noh G, Choi WS, Cho S, Lee SS (2011) Allergenspecific transforming growth factor-beta-producing CD19+ CD5+ regulatory B-cell (Br3) responses in human late eczematous allergic reactions to cow's milk. J Interferon Cytokine Res 31:441-449
-
(2011)
J Interferon Cytokine Res
, vol.31
, pp. 441-449
-
-
Lee, J.H.1
Noh, J.2
Noh, G.3
Choi, W.S.4
Cho, S.5
Lee, S.S.6
-
99
-
-
77951667958
-
Regulatory b cells prevent and reverse allergic airway inflammation via foxp3-positive t regulatory cells in a murine model
-
Amu S, Saunders SP, Kronenberg M, Mangan NE, Atzberger A, Fallon PG (2011) Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model. J Allergy Clin Immunol 125(1114-1124):e1118
-
(2011)
J Allergy Clin Immunol
, vol.125
, Issue.1114-1124
-
-
Amu, S.1
Saunders, S.P.2
Kronenberg, M.3
Mangan, N.E.4
Atzberger, A.5
Fallon, P.G.6
-
100
-
-
79956224216
-
Mice lacking endogenous il-10-producing regulatory b cells develop exacerbated disease and present with an increased frequency of th1/th17 but a decrease in regulatory t cells
-
Carter NA, Vasconcellos R, Rosser EC et al (2011) Mice lacking endogenous IL-10-producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells. J Immunol 186:5569-5579
-
(2011)
J Immunol
, vol.186
, pp. 5569-5579
-
-
Carter, N.A.1
Vasconcellos, R.2
Rosser, E.C.3
-
101
-
-
34248230257
-
Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis
-
Duddy M, Niino M, Adatia F et al (2007) Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis. J Immunol 178:6092-6099 (Pubitemid 46717389)
-
(2007)
Journal of Immunology
, vol.178
, Issue.10
, pp. 6092-6099
-
-
Duddy, M.1
Niino, M.2
Adatia, F.3
Hebert, S.4
Freedman, M.5
Atkins, H.6
Ho, J.K.7
Bar-Or, A.8
-
102
-
-
77957164949
-
Il-10 produced by activated human b cells regulates cd4(+) t-cell activation in vitro
-
Bouaziz JD, Calbo S, Maho-Vaillant M et al (2010) IL-10 produced by activated human B cells regulates CD4(+) T-cell activation in vitro. Eur J Immunol 40:2686-2691
-
(2010)
Eur J Immunol
, vol.40
, pp. 2686-2691
-
-
Bouaziz, J.D.1
Calbo, S.2
Maho-Vaillant, M.3
-
103
-
-
74649083783
-
Cd19(+)cd24 (hi)cd38(hi) b cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
-
Blair PA, Norena LY, Flores-Borja F et al (2010) CD19(+)CD24 (hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients. Immunity 32:129-140
-
(2010)
Immunity
, vol.32
, pp. 129-140
-
-
Blair, P.A.1
Norena, L.Y.2
Flores-Borja, F.3
-
104
-
-
78751469622
-
Characterization of a rare il-10-competent b-cell subset in humans that parallels mouse regulatory b10 cells
-
Iwata Y, Matsushita T, Horikawa M et al (2010) Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood 117:530-541
-
(2010)
Blood
, vol.117
, pp. 530-541
-
-
Iwata, Y.1
Matsushita, T.2
Horikawa, M.3
-
105
-
-
0033428703
-
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
-
DOI 10.1084/jem.190.11.1697
-
Mackay F, Woodcock SA, Lawton P et al (1999) Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190:1697-1710 (Pubitemid 30002351)
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.11
, pp. 1697-1710
-
-
Mackay, F.1
Woodcock, S.A.2
Lawton, P.3
Ambrose, C.4
Baetscher, M.5
Schneider, P.6
Tschopp, J.7
Browning, J.L.8
-
106
-
-
12944249540
-
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
-
DOI 10.1073/pnas.050580697
-
Khare SD, Sarosi I, Xia XZ et al (2000) Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci U S A 97:3370-3375 (Pubitemid 30183309)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3370-3375
-
-
Khare, S.D.1
Sarosi, I.2
Xia, X.-Z.3
McCabe, S.4
Miner, K.5
Solovyev, I.6
Hawkins, N.7
Kelley, M.8
Chang, D.9
Van, G.10
Ross, L.11
Delaney, J.12
Wang, L.13
Lacey, D.14
Boyle, W.J.15
Hsu, H.16
-
107
-
-
0037386743
-
Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis
-
DOI 10.1002/art.10860
-
Tan SM, Xu D, Roschke V et al (2003) Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum 48:982-992 (Pubitemid 36418240)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.4
, pp. 982-992
-
-
Tan, S.-M.1
Xu, D.2
Roschke, V.3
Perry, J.W.4
Arkfeld, D.G.5
Ehresmann, G.R.6
Migone, T.-S.7
Hilbert, D.M.8
Stohl, W.9
-
108
-
-
33847342813
-
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells
-
Ettinger R, Sims GP, Robbins R et al (2007) IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J Immunol 178:2872-2882 (Pubitemid 46333165)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 2872-2882
-
-
Ettinger, R.1
Sims, G.P.2
Robbins, R.3
Withers, D.4
Fischer, R.T.5
Grammer, A.C.6
Kuchen, S.7
Lipsky, P.E.8
-
109
-
-
67649197343
-
Interleukin 17 acts in synergy with b cell-Activating factor to influence b cell biology and the pathophysiology of systemic lupus erythematosus
-
Doreau A, Belot A, Bastid J et al (2009) Interleukin 17 acts in synergy with B cell-Activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol 10:778-785
-
(2009)
Nat Immunol
, vol.10
, pp. 778-785
-
-
Doreau, A.1
Belot, A.2
Bastid, J.3
-
110
-
-
0036732753
-
Dcs induce cd40-independent immunoglobulin class switching through blys and april
-
Litinskiy MB, Nardelli B, Hilbert DM et al (2002) DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 3:822-829
-
(2002)
Nat Immunol
, vol.3
, pp. 822-829
-
-
Litinskiy, M.B.1
Nardelli, B.2
Hilbert, D.M.3
-
111
-
-
41949138741
-
April is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells
-
Belnoue E, Pihlgren M, McGaha TL et al (2008) APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood 111:2755-2764
-
(2008)
Blood
, vol.111
, pp. 2755-2764
-
-
Belnoue, E.1
Pihlgren, M.2
McGaha, T.L.3
-
112
-
-
35648945384
-
Expression of BAFF and BAFF-R in the synovial tissue of patients with rheumatoid arthritis
-
DOI 10.1080/03009740701286615, PII 783463936
-
Nakajima K, Itoh K, Nagatani K et al (2007) Expression of BAFF and BAFF-R in the synovial tissue of patients with rheumatoid arthritis. Scand J Rheumatol 36:365-372 (Pubitemid 350034808)
-
(2007)
Scandinavian Journal of Rheumatology
, vol.36
, Issue.5
, pp. 365-372
-
-
Nakajima, K.1
Itoh, K.2
Nagatani, K.3
Okawa-Takatsuji, M.4
Fujii, T.5
Kuroki, H.6
Katsuragawa, Y.7
Aotsuka, S.8
Mimori, A.9
-
113
-
-
67349198177
-
Infiltrations of plasma cells in synovium are highly associated with synovial fluid levels of april in inflamed peripheral joints of rheumatoid arthritis
-
Dong W, Li X, Liu H, Zhu P (2009) Infiltrations of plasma cells in synovium are highly associated with synovial fluid levels of APRIL in inflamed peripheral joints of rheumatoid arthritis. Rheumatol Int 29:801-806
-
(2009)
Rheumatol Int
, vol.29
, pp. 801-806
-
-
Dong, W.1
Li, X.2
Liu, H.3
Zhu, P.4
-
114
-
-
17344380531
-
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
-
DOI 10.1038/35010115
-
Gross JA, Johnston J, Mudri S et al (2000) TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404:995-999 (Pubitemid 30243593)
-
(2000)
Nature
, vol.404
, Issue.6781
, pp. 995-999
-
-
Gross, J.A.1
Johnston, J.2
Mudri, S.3
Enselman, R.4
Dillon, S.R.5
Madden, K.6
Xu, W.7
Parrish-Novak, J.8
Foster, D.9
Lofton-Day, C.10
Moore, M.11
Littau, A.12
Grossman, A.13
Haugen, H.14
Foley, K.15
Blumberg, H.16
Harrison, K.17
Kindsvogel, W.18
Clegg, C.H.19
-
115
-
-
18644369740
-
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2
-
DOI 10.1016/S1074-7613(02)00425-9
-
Kayagaki N, Yan M, Seshasayee D et al (2002) BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity 17:515-524 (Pubitemid 35223539)
-
(2002)
Immunity
, vol.17
, Issue.4
, pp. 515-524
-
-
Kayagaki, N.1
Yan, M.2
Seshasayee, D.3
Wang, H.4
Lee, W.5
French, D.M.6
Grewal, I.S.7
Cochran, A.G.8
Gordon, N.C.9
Yin, J.10
Starovasnik, M.A.11
Dixit, V.M.12
-
116
-
-
38149114077
-
Atacicept in patients with rheumatoid arthritis: Results of a multicenter, phase ib, double-blind, placebo-controlled, dose-escalating, single-And repeated-dose study
-
Tak PP, Thurlings RM, Rossier C et al (2008) Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single-And repeated-dose study. Arthritis Rheum 58:61-72
-
(2008)
Arthritis Rheum
, vol.58
, pp. 61-72
-
-
Tak, P.P.1
Thurlings, R.M.2
Rossier, C.3
-
117
-
-
82455198794
-
A phase iii, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits b lymphocyte stimulator, in patients with systemic lupus erythematosus
-
Furie R, Petri M, Zamani O et al (2011) A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus. Arthritis Rheum 63:3918-3930
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3918-3930
-
-
Furie, R.1
Petri, M.2
Zamani, O.3
-
118
-
-
0023851809
-
The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells
-
Muraguchi A, Hirano T, Tang B et al (1988) The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells. J Exp Med 167:332-344 (Pubitemid 18073639)
-
(1988)
Journal of Experimental Medicine
, vol.167
, Issue.2
, pp. 332-344
-
-
Muraguchi, A.1
Hirano, T.2
Tang, B.3
Matsuda, T.4
Horii, Y.5
Nakajima, K.6
Kishimoto, T.7
-
119
-
-
79955569760
-
In vivo effect of the anti interleukin-6 receptor inhibitor tocilizumab on the b-cell compartment
-
Roll, P., Muhammad, K., Schumann, M., et al. (2011), In vivo effect of the anti interleukin-6 receptor inhibitor tocilizumab on the B-cell compartment. Arthritis Rheum
-
(2011)
Arthritis Rheum
-
-
Roll, P.1
Muhammad, K.2
Schumann, M.3
-
120
-
-
83255164803
-
In rheumatoid arthritis patients treated with tocilizumab, the rate of clinical disease activity index (cdai) remission at 24 weeks is superior in those with higher titers of igm-rheumatoid factor at baseline
-
Kawashiri, S. Y., Kawakami, A., Iwamoto, N., et al. (2011), In rheumatoid arthritis patients treated with tocilizumab, the rate of clinical disease activity index (CDAI) remission at 24 weeks is superior in those with higher titers of IgM-rheumatoid factor at baseline. Mod Rheumatol
-
(2011)
Mod Rheumatol
-
-
Kawashiri, S.Y.1
Kawakami, A.2
Iwamoto, N.3
-
121
-
-
79959807954
-
Impact of il-6 receptor inhibition on human memory b cells in vivo: Impaired somatic hypermutation in preswitch memory b cells and modulation of mutational targeting in memory b cells
-
Muhammad K, Roll P, Seibold T et al (2011) Impact of IL-6 receptor inhibition on human memory B cells in vivo: impaired somatic hypermutation in preswitch memory B cells and modulation of mutational targeting in memory B cells. Ann Rheum Dis 70:1507-1510
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1507-1510
-
-
Muhammad, K.1
Roll, P.2
Seibold, T.3
|