CD45RA-Foxp3high activated/effector regulatory T cells in the CCR7+CD45RA-CD27+CD28+central memory subset are decreased in peripheral blood from patients with rheumatoid arthritis

Biochemical and Biophysical Research Communications

Volumn 438, Issue 4, 2013, Pages 778-783

  Matsuki, Fumichika ^a   Saegusa, Jun ^a   Miyamoto, Yoshiaki ^a   Misaki, Kenta ^a   Kumagai, Shunichi ^a,b   Morinobu, Akio ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Shinko Hospital   (Japan)

Author keywords

Activated effector Treg cells; Central memory T cells; Effector memory T cells; Inflammatory cytokines; Regulatory T cells; Rheumatoid arthritis

Indexed keywords

CD27 ANTIGEN; CD28 ANTIGEN; CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR7; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIGEN EXPRESSION; ARTICLE; BLOOD; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; HUMAN; HUMAN CELL; MALE; MEMORY T LYMPHOCYTE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RHEUMATOID ARTHRITIS;

ACTIVATED/EFFECTOR TREG CELLS; CENTRAL MEMORY T CELLS; CTLA4; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; DAS28M; DC; DENDRITIC CELL; DISEASE ACTIVITY SCORE FOR 28 JOINTS; DISEASE-MODIFYING ANTI-RHEUMATIC DRUG; DMARD; ECD; EFFECTOR MEMORY T CELLS; ENERGY-COUPLED DYE; FORKHEAD BOX P3; FOXP3; HCPB; INFLAMMATORY CYTOKINES; PB; PERCPCY5.5; PERIDIN CHLOROPHYLL PROTEIN-CYANIN 5.5; PERIPHERAL BLOOD; PERIPHERAL BLOOD FROM HEALTHY CONTROLS; PERIPHERAL BLOOD FROM RA PATIENTS; RA; RAPB; REGULATORY T CELLS; RHEUMATOID ARTHRITIS; SLE; SYSTEMIC LUPUS ERYTHEMATOSUS; T(CM); T(EM); TREG;

ADULT; ANTIGENS, CD27; ANTIGENS, CD28; ANTIGENS, CD45; ARTHRITIS, RHEUMATOID; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; RECEPTORS, CCR7; T-LYMPHOCYTES, REGULATORY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84883297026     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.120     Document Type: Article

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