CTLA4-Ig (abatacept) therapy modulates T cell effector functions in autoantibody-positive rheumatoid arthritis patients

BMC Immunology

Volumn 14, Issue 1, 2013, Pages

  Pieper, Jennifer ^a   Herrath, Jessica ^a   Raghavan, Sukanya ^a   Muhammad, Khalid ^a   Vollenhoven, Ronald van ^a   Malmström, Vivianne ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Abatacept; ACPA; Autoimmunity; Cytokines; Regulatory T cells; Rheumatoid arthritis; T lymphocyte

Indexed keywords

ABATACEPT; AUTOANTIBODY; CD4 ANTIGEN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CELL CULTURE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; FUNCTIONAL STATUS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MALE; REGULATORY T LYMPHOCYTE; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; TH2 CELL; TREATMENT DURATION;

ADOLESCENT; ADULT; AGED; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; CELL PROLIFERATION; CITRULLINE; COHORT STUDIES; CYTOKINES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOCONJUGATES; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; SYNOVIAL MEMBRANE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84881041617     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-14-34     Document Type: Article

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