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Volumn 7, Issue 15, 2008, Pages 2346-2351

The eIF2α kinases inhibit vesicular stomatitis virus replication independently of eIF2α phosphorylation

Author keywords

Antiviral; eIF2 ; eIF2 kinases; PI3K pathway; VSV

Indexed keywords

INITIATION FACTOR 2ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE R; ANTIVIRUS AGENT; INITIATION FACTOR 2; ISOENZYME;

EID: 48849096740     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.6323     Document Type: Article
Times cited : (41)

References (52)
  • 1
    • 0037154965 scopus 로고    scopus 로고
    • Gene-specific regulation by general translation factors
    • Dever TE. Gene-specific regulation by general translation factors. Cell 2002; 108:545-56.
    • (2002) Cell , vol.108 , pp. 545-556
    • Dever, T.E.1
  • 2
    • 33947584856 scopus 로고    scopus 로고
    • Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: Relevance to anemias
    • Chen JJ. Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias. Blood 2007; 109:2693-9.
    • (2007) Blood , vol.109 , pp. 2693-2699
    • Chen, J.J.1
  • 3
    • 0035225871 scopus 로고    scopus 로고
    • Regulation of translation initiation by amino acids in eukaryotic cells
    • Kimball SR. Regulation of translation initiation by amino acids in eukaryotic cells. Prog Mol Subcell Biol 2001; 26:155-84.
    • (2001) Prog Mol Subcell Biol , vol.26 , pp. 155-184
    • Kimball, S.R.1
  • 4
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007; 8:519-29.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 5
    • 0034767753 scopus 로고    scopus 로고
    • Antiviral actions of interferons
    • Samuel CE. Antiviral actions of interferons. Clin Microbiol Rev 2001; 14:778-809.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 778-809
    • Samuel, C.E.1
  • 7
    • 12344251814 scopus 로고    scopus 로고
    • Translational control in virus-infected cells: Models for cellular stress responses
    • Clemens MJ. Translational control in virus-infected cells: models for cellular stress responses. Semin Cell Dev Biol 2005; 16:13-20.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 13-20
    • Clemens, M.J.1
  • 8
    • 0036715591 scopus 로고    scopus 로고
    • Viruses and interferon: A fight for supremacy
    • Katze MG, He Y, Gale M Jr. Viruses and interferon: a fight for supremacy. Nat Rev Immunol 2002; 2:675-87.
    • (2002) Nat Rev Immunol , vol.2 , pp. 675-687
    • Katze, M.G.1    He, Y.2    Gale Jr., M.3
  • 9
    • 0034682720 scopus 로고    scopus 로고
    • Initiation of protein synthesis from the A site of the ribosome
    • Wilson JE, Pestova TV, Hellen CU, Sarnow P. Initiation of protein synthesis from the A site of the ribosome. Cell 2000; 102:511-20.
    • (2000) Cell , vol.102 , pp. 511-520
    • Wilson, J.E.1    Pestova, T.V.2    Hellen, C.U.3    Sarnow, P.4
  • 13
    • 0036209493 scopus 로고    scopus 로고
    • PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependent
    • Durbin RK, Mertz SE, Koromilas AE, Durbin JE. PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependent. Viral Immunol 2002; 15:41-51.
    • (2002) Viral Immunol , vol.15 , pp. 41-51
    • Durbin, R.K.1    Mertz, S.E.2    Koromilas, A.E.3    Durbin, J.E.4
  • 16
    • 0036209493 scopus 로고    scopus 로고
    • PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependent
    • Durbin RK, Mertz SE, Koromilas AE, Durbin JE. PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependent. Viral Immunol 2002; 15:41-51.
    • (2002) Viral Immunol , vol.15 , pp. 41-51
    • Durbin, R.K.1    Mertz, S.E.2    Koromilas, A.E.3    Durbin, J.E.4
  • 17
    • 8644224931 scopus 로고    scopus 로고
    • Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR
    • Baltzis D, Qu LK, Papadopoulou S, Blais JD, Bell JC, Sonenberg N, Koromilas AE. Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR. J Virol 2004; 78:12747-61.
    • (2004) J Virol , vol.78 , pp. 12747-12761
    • Baltzis, D.1    Qu, L.K.2    Papadopoulou, S.3    Blais, J.D.4    Bell, J.C.5    Sonenberg, N.6    Koromilas, A.E.7
  • 18
    • 33646152751 scopus 로고    scopus 로고
    • Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses
    • Berlanga JJ, Ventoso I, Harding HP, Deng J, Ron D, Sonenberg N, Carrasco L, de HC. Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses. EMBO J 2006; 25:1730-40.
    • (2006) EMBO J , vol.25 , pp. 1730-1740
    • Berlanga, J.J.1    Ventoso, I.2    Harding, H.P.3    Deng, J.4    Ron, D.5    Sonenberg, N.6    Carrasco, L.7    de, H.C.8
  • 19
    • 0033634641 scopus 로고    scopus 로고
    • Perk is essential for translational regulation and cell survival during the unfolded protein response
    • Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 2000; 5:897-904.
    • (2000) Mol Cell , vol.5 , pp. 897-904
    • Harding, H.P.1    Zhang, Y.2    Bertolotti, A.3    Zeng, H.4    Ron, D.5
  • 21
    • 17944362905 scopus 로고    scopus 로고
    • Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency
    • Han AP, Yu C, Lu L, Fujiwara Y, Browne C, Chin G, Fleming M, Leboulch P, Orkin SH, Chen JJ. Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency. EMBO J 2001; 20:6909-18.
    • (2001) EMBO J , vol.20 , pp. 6909-6918
    • Han, A.P.1    Yu, C.2    Lu, L.3    Fujiwara, Y.4    Browne, C.5    Chin, G.6    Fleming, M.7    Leboulch, P.8    Orkin, S.H.9    Chen, J.J.10
  • 23
  • 24
    • 0035898611 scopus 로고    scopus 로고
    • Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR
    • Ung TL, Cao C, Lu J, Ozato K, Dever TE. Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR. EMBO J 2001; 20:3728-37.
    • (2001) EMBO J , vol.20 , pp. 3728-3737
    • Ung, T.L.1    Cao, C.2    Lu, J.3    Ozato, K.4    Dever, T.E.5
  • 25
    • 1842505312 scopus 로고    scopus 로고
    • Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: Implications for eIF2 alpha-dependent gene expression and cell death
    • Kazemi S, Papadopoulou S, Li S, Su Q, Wang S, Yoshimura A, Matlashewski G, Dever TE, Koromilas AE. Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death. Mol Cell Biol 2004; 24:3415-29.
    • (2004) Mol Cell Biol , vol.24 , pp. 3415-3429
    • Kazemi, S.1    Papadopoulou, S.2    Li, S.3    Su, Q.4    Wang, S.5    Yoshimura, A.6    Matlashewski, G.7    Dever, T.E.8    Koromilas, A.E.9
  • 27
    • 0028815704 scopus 로고
    • Regulation of the interferon-induced PKR: Can viruses cope?
    • Katze MG. Regulation of the interferon-induced PKR: can viruses cope? Trends in Microbiology 1995; 3:75-8.
    • (1995) Trends in Microbiology , vol.3 , pp. 75-78
    • Katze, M.G.1
  • 28
    • 0037064118 scopus 로고    scopus 로고
    • Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR
    • Baltzis D, Li S, Koromilas AE. Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR. J Biol Chem 2002; 277:38364-72.
    • (2002) J Biol Chem , vol.277 , pp. 38364-38372
    • Baltzis, D.1    Li, S.2    Koromilas, A.E.3
  • 34
    • 33746361817 scopus 로고    scopus 로고
    • Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis
    • Scheuner D, Patel R, Wang F, Lee K, Kumar K, Wu J, Nilsson A, Karin M, Kaufman RJ. Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis. J Biol Chem 2006; 281:21458-68.
    • (2006) J Biol Chem , vol.281 , pp. 21458-21468
    • Scheuner, D.1    Patel, R.2    Wang, F.3    Lee, K.4    Kumar, K.5    Wu, J.6    Nilsson, A.7    Karin, M.8    Kaufman, R.J.9
  • 35
    • 34447560071 scopus 로고    scopus 로고
    • Function of RIG-I-like receptors in antiviral innate immunity
    • Yoneyama M, Fujita T. Function of RIG-I-like receptors in antiviral innate immunity. J Biol Chem 2007; 282:15315-8.
    • (2007) J Biol Chem , vol.282 , pp. 15315-15318
    • Yoneyama, M.1    Fujita, T.2
  • 36
    • 33847349804 scopus 로고    scopus 로고
    • Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2
    • Su Q, Wang S, Baltzis D, Qu LK, Raven JF, Li S, Wong AH, Koromilas AE. Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2. EMBO Rep 2007; 8:265-70.
    • (2007) EMBO Rep , vol.8 , pp. 265-270
    • Su, Q.1    Wang, S.2    Baltzis, D.3    Qu, L.K.4    Raven, J.F.5    Li, S.6    Wong, A.H.7    Koromilas, A.E.8
  • 37
    • 0343852938 scopus 로고    scopus 로고
    • Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways
    • Wong AH, Tam NW, Yang YL, Cuddihy AR, Li S, Kirchhoff S, Hauser H, Decker T, Koromilas AE. Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways. EMBO J 1997; 16:1291-304.
    • (1997) EMBO J , vol.16 , pp. 1291-1304
    • Wong, A.H.1    Tam, N.W.2    Yang, Y.L.3    Cuddihy, A.R.4    Li, S.5    Kirchhoff, S.6    Hauser, H.7    Decker, T.8    Koromilas, A.E.9
  • 38
    • 0035958080 scopus 로고    scopus 로고
    • Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR
    • Wong AH, Durbin JE, Li S, Dever TE, Decker T, Koromilas AE. Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR. J Biol Chem 2001; 276:13727-37.
    • (2001) J Biol Chem , vol.276 , pp. 13727-13737
    • Wong, A.H.1    Durbin, J.E.2    Li, S.3    Dever, T.E.4    Decker, T.5    Koromilas, A.E.6
  • 39
    • 33646909758 scopus 로고    scopus 로고
    • The catalytic activity of the eukaryotic initiation factor-2alpha kinase PKR is required to negatively regulate Stat1 and Stat3 via activation of the T-cell protein-tyrosine phosphatase
    • Wang S, Raven JF, Baltzis D, Kazemi S, Brunet DV, Hatzoglou M, Tremblay ML, Koromilas AE. The catalytic activity of the eukaryotic initiation factor-2alpha kinase PKR is required to negatively regulate Stat1 and Stat3 via activation of the T-cell protein-tyrosine phosphatase. J Biol Chem 2006; 281:9439-49.
    • (2006) J Biol Chem , vol.281 , pp. 9439-9449
    • Wang, S.1    Raven, J.F.2    Baltzis, D.3    Kazemi, S.4    Brunet, D.V.5    Hatzoglou, M.6    Tremblay, M.L.7    Koromilas, A.E.8
  • 42
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • Durbin JE, Hackenmiller R, Simon MC, Levy DE. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 1996; 84:443-50.
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 44
    • 10344222124 scopus 로고    scopus 로고
    • The role of the unfolded protein response in tumour development: Friend or foe?
    • Ma Y, Hendershot LM. The role of the unfolded protein response in tumour development: friend or foe? Nat Rev Cancer 2004; 4:966-77.
    • (2004) Nat Rev Cancer , vol.4 , pp. 966-977
    • Ma, Y.1    Hendershot, L.M.2
  • 45
    • 4143126659 scopus 로고    scopus 로고
    • Replication and cytopathic effect of oncolytic vesicular stomatitis virus in hypoxic tumor cells in vitro and in vivo
    • Connor JH, Naczki C, Koumenis C, Lyles DS. Replication and cytopathic effect of oncolytic vesicular stomatitis virus in hypoxic tumor cells in vitro and in vivo. J Virol 2004; 78:8960-70.
    • (2004) J Virol , vol.78 , pp. 8960-8970
    • Connor, J.H.1    Naczki, C.2    Koumenis, C.3    Lyles, D.S.4
  • 46
    • 28844444483 scopus 로고    scopus 로고
    • Recent progress in the battle between oncolytic viruses and tumours
    • Parato KA, Senger D, Forsyth PA, Bell JC. Recent progress in the battle between oncolytic viruses and tumours. Nat Rev Cancer 2005; 5:965-76.
    • (2005) Nat Rev Cancer , vol.5 , pp. 965-976
    • Parato, K.A.1    Senger, D.2    Forsyth, P.A.3    Bell, J.C.4
  • 47
    • 0036785522 scopus 로고    scopus 로고
    • Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1
    • Connor JH, Lyles DS. Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1. J Virol 2002; 76:10177-87.
    • (2002) J Virol , vol.76 , pp. 10177-10187
    • Connor, J.H.1    Lyles, D.S.2
  • 48
    • 17144377430 scopus 로고    scopus 로고
    • Inhibition of Host and Viral Translation during Vesicular Stomatitis Virus Infection: EIF2 IS RESPONSIBLE FOR THE INHIBITION OF VIRAL BUT NOT HOST TRANSLATION
    • Connor JH, Lyles DS. Inhibition of Host and Viral Translation during Vesicular Stomatitis Virus Infection: eIF2 IS RESPONSIBLE FOR THE INHIBITION OF VIRAL BUT NOT HOST TRANSLATION. J Biol Chem 2005; 280:13512-9.
    • (2005) J Biol Chem , vol.280 , pp. 13512-13519
    • Connor, J.H.1    Lyles, D.S.2
  • 51
    • 0035957939 scopus 로고    scopus 로고
    • Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR
    • Li S, Koromilas AE. Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR. J Biol Chem 2001; 276:13881-90.
    • (2001) J Biol Chem , vol.276 , pp. 13881-13890
    • Li, S.1    Koromilas, A.E.2
  • 52
    • 0037064118 scopus 로고    scopus 로고
    • Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR
    • Baltzis D, Li S, Koromilas AE. Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR. J Biol Chem 2002; 277:38364-72.
    • (2002) J Biol Chem , vol.277 , pp. 38364-38372
    • Baltzis, D.1    Li, S.2    Koromilas, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.