Newly discovered endocrine functions of white adipose tissue: Possible relevance in obesity-related diseases

Cellular and Molecular Life Sciences

Volumn 62, Issue 12, 2005, Pages 1359-1362

  Krug, A W ^a   Ehrhart Bornstein, M ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Adipocyte; Adipokines; Adipose tissue; Endocrine; Hypertension; Inflammation; Obesity

Indexed keywords

ADIPOCYTOKINE; UNCLASSIFIED DRUG; VISFATIN;

ADIPOCYTE; BLOOD PRESSURE MONITORING; ENDOCRINE FUNCTION; ENERGY; HUMAN; HYPERTENSION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PATHOPHYSIOLOGY; REVIEW; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; ANIMALS; ENDOCRINE SYSTEM DISEASES; HUMANS; OBESITY;

EID: 20744456715     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-005-4555-z     Document Type: Review

References (33)

1. Cook K. S., Groves D. L., Min H. Y. and Spiegelman B. M. (1985) A developmental regulated mRNA from 3T3 adipocytes encodes a novel serine protease homologue. Proc. Natl. Acad. Sci. USA 82: 6480-6484
2. Cook K. S. Min, H. Y. Johnson D., Chaplinsky R. J., Flier J. S., Hunt C. R. et al. (1987) Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science 237: 402-405
3. Hotamisligil G. S., Shargill N. S. and Spiegelman B. M. (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259: 87-91
4. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L. and Friedman J. M. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432
5. Kratchmarova I., Kalume D. E., Blagoev B., Scherer P. E., Podtelejnikov A. V., Molina H. et al. (2002) A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Mol. Cell. Proteomics 1: 213-222
6. Wang P., Mariman E., Keijer J., Bouwman F., Noben J. P., Robben J. et al. (2004) Profiling of the secreted proteins during 3T3-L1 adipocyte differentiation leads to the identification of novel adipokines. Cell. Mol. Life Sci. 61: 2405-2417
7. Kersten S., Mandard S., Tan N. S., Escher P., Metzger D., Chambon P. et al. (2000) Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J. Biol. Chem. 275: 28488-28493
8. Backhed F., Ding H., Wang T., Hooper L. V., Koh G. Y., Nagy A. et al. (2004) The gut microbiota as an environmental factor that regulates fat storage. Proc. Natl. Acad. Sci. USA 101: 15718-15723
9. Fukuhara A., Matsuda M., Nishizawa M., Segawa K. Tanaka, M., Kishimoto et al. (2005) Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 307: 426-430
10. Boucher J., Masri B., Daviaud D., Gesta S., Guigne C., Mazzucotelli A. et al. (2005) Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology 146: 1764-1771
11. Trayhurn P. and Wood I. S. (2004) Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br. J. Nutr. 92: 347-355
12. Rajala M. W. and Scherer P. E. (2003) Minireview: the adipocyte - at the crossroads of energy homeostasis, inflammation and atherosclerosis. Endocrinology 144: 3765-3773
13. Lyon C. J., Law R. E. and Hsueh W. A. (2003) Minireview: adiposity, inflammation and atherogenesis. Endocrinology 144: 2195-2200
14. Weisberg S. P., McCann D., Desai M., Rosenbaum M., Leibel R. L. and Ferrante A. W. Jr (2003) Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112: 1796-1808
15. Xu H., Barnes G. T., Yang Q., Tan G., Yang D., Chou C. J. et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112: 1821-1830
16. Skurk T., Herder C., Kraft I., Muller-Scholze S., Hauner H., and Kolb H. (2005) Production and release of macrophage migration inhibitory factor from human adipocytes. Endocrinology 146: 1006-1111
17. Hall J. E. (2003) The kidney, hypertension and obesity. Hypertension 41: 625-633
18. Lamounier-Zepter V., Bornstein S. R. and Ehrhart-Bornstein M. (2004) Mechanisms of obesity-related hypertension. Horm. Metab. Res. 36: 376-380
19. Goodfriend T. L., Egan B. M. and Kelley D. E. (1998) Aldosterone in obesity. Endocr. Res. 24: 789-796
20. El Gharbawy A. H., Nadig V. S., Kotchen J. M., Grim C. E., Sagar K. B., Kaldunski M. et al. (2001) Arterial pressure, left ventricular mass and aldosterone in essential hypertension. Hypertension 37: 845-850
21. Ehrhart-Bornstein M., Lamounier-Zepter V., Schraven A., Langenbach J., Willenberg H. S., Barthel A. et al. (2003) Human adipocytes secrete mineralocorticoid-releasing factors. Proc. Natl. Acad. Sci. USA 100: 14211-14216
22. Lin Y., Rajala M. W., Berger J. P., Moller D. E., Barzilai N. and Scherer P. E. (2001) Hyperglycemia-induced production of acute phase reactants in adipose tissue. J. Biol. Chem. 276: 42077-42083
23. Saleh J., Summers L. K., Cianflone K., Fielding B. A., Sniderman A. D. and Frayn K. N. (1998) Coordinated release of acylation stimulating protein (ASP) and triacylglycerol clearance by human adipose tissue in vivo in the postprandial period. J. Lipid Res. 39: 884-891
24. Goldstein B. J. and Scalia R. (2004) Adiponectin: a novel adipokine linking adipocytes and vascular function. J. Clin. Endocrinol. Metab. 89: 2563-2568
25. Polson D. A. and Thompson M. P. (2003) Adiponutrin mRNA expression in white adipose tissue is rapidly induced by meal-feeding a high-sucrose diet. Biochem. Biophys. Res. Commun. 301: 261-266
26. Jones B. H., Standridge M. K., Taylor J. W. and Moustaid N. (1997) Angiotensinogen gene expression in adipose tissue: analysis of obese models and hormonal and nutritional control. Am. J. Physiol. 273: R236-R242
27. Friedrichs W. E., Navarijo-Ashbaugh A. L., Bowman B. H. and Yang F. (1995) Expression and inflammatory regulation of haptoglobin gene in adipocytes. Biochem. Biophys. Res. Commun. 209: 250-256
28. Coppack S. W., Yost T. J., Fisher R. M., Eckel R. H. and Miles J. M. (1996) Periprandial systemic and regional lipase activity in normal humans. Am. J. Physiol. 270: E718-E722
29. Peeraully M. R., Jenkins J. R. and Trayhurn P. (2004) NGF gene expression and secretion in white adipose tissue: regulation in 3T3-L1 adipocytes by hormones and inflammatory cytokines. Am. J. Physiol. Endocrinol. Metab. 287: E331-E339
30. Lundgren C. H., Brown S. L., Nordt T. K., Sobel B. E. and Fujii S. (1996) Elaboration of type-1 plasminogen activator inhibitor from adipocytes. A potential pathogenetic link between obesity and cardiovascular disease. Circulation 93: 106-110
31. Steppan C. M., Bailey S. T., Bhat S., Brown E. J., Banerjee R. R., Wright C. M. et al. (2001) The hormone resistin links obesity to diabetes. Nature 409: 307-312
32. Boulton K. L., Hudson D. U., Coppack S. W. and Frayn K. N. (1992) Steroid hormone interconversions in human adipose tissue in vivo. Metabolism 41: 556-559
33. Mohamed-Ali V., Goodrick S., Bulmer K., Holly J. M., Yudkin J. S. and Coppack S. W. (1999) Production of soluble tumor necrosis factor receptors by human subcutaneous adipose tissue in vivo. Am. J. Physiol. 277: E971-E975