메뉴 건너뛰기




Volumn 24, Issue 6, 2010, Pages 1997-2009

Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis

Author keywords

Cell death; Death receptor; Preadipocytes

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CYTOCHROME C; FAS ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; RESVERATROL; SIRTUIN 1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 77953521260     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-142943     Document Type: Article
Times cited : (74)

References (64)
  • 2
    • 33644856005 scopus 로고    scopus 로고
    • Obesity and the role of adipose tissue in inflammation and metabolism
    • Greenberg, A. S., and Obin, M. S. (2006) Obesity and the role of adipose tissue in inflammation and metabolism. Am. J. Clin. Nutr. 83, 461S-465S
    • (2006) Am. J. Clin. Nutr. , vol.83
    • Greenberg, A.S.1    Obin, M.S.2
  • 4
    • 0038039463 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha: A key regulator of adipose tissue mass
    • Warne, J. P. (2003) Tumour necrosis factor alpha: a key regulator of adipose tissue mass. J. Endocrinol. 177, 351-355
    • (2003) J. Endocrinol. , vol.177 , pp. 351-355
    • Warne, J.P.1
  • 6
    • 65449152836 scopus 로고    scopus 로고
    • Following TRAIL's path in the immune system
    • Falschlehner, C., Schaefer, U., and Walczak, H. (2009) Following TRAIL's path in the immune system. Immunology 127, 145-154
    • (2009) Immunology , vol.127 , pp. 145-154
    • Falschlehner, C.1    Schaefer, U.2    Walczak, H.3
  • 7
    • 0037312020 scopus 로고    scopus 로고
    • How does calorie restriction work?
    • Koubova, J., and Guarente, L. (2003) How does calorie restriction work? Genes Dev. 17, 313-321
    • (2003) Genes Dev. , vol.17 , pp. 313-321
    • Koubova, J.1    Guarente, L.2
  • 8
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • Bluher, M., Kahn, B. B., and Kahn, C. R. (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299, 572-574
    • (2003) Science , vol.299 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 11
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • Wood, J. G., Rogina, B., Lavu, S., Howitz, K., Helfand, S. L., Tatar, M., and Sinclair, D. (2004) Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430, 686-689
    • (2004) Nature , vol.430 , pp. 686-689
    • Wood, J.G.1    Rogina, B.2    Lavu, S.3    Howitz, K.4    Helfand, S.L.5    Tatar, M.6    Sinclair, D.7
  • 12
    • 33751113602 scopus 로고    scopus 로고
    • Mammalian sirtuins - Emerging roles in physiology, aging, and calorie restriction
    • Haigis, M. C., and Guarente, L. P. (2006) Mammalian sirtuins - emerging roles in physiology, aging, and calorie restriction. Genes Dev. 20, 2913-2921
    • (2006) Genes Dev. , vol.20 , pp. 2913-2921
    • Haigis, M.C.1    Guarente, L.P.2
  • 14
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur, J. A., and Sinclair, D. A. (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat. Rev. Drug Discov. 5, 493-506
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 16
    • 33746734833 scopus 로고    scopus 로고
    • Resveratrol modulation of signal transduction in apoptosis and cell survival: A mini-review
    • Fulda, S., and Debatin, K. M. (2006) Resveratrol modulation of signal transduction in apoptosis and cell survival: a mini-review. Cancer Detect. Prev. 30, 217-223
    • (2006) Cancer Detect. Prev. , vol.30 , pp. 217-223
    • Fulda, S.1    Debatin, K.M.2
  • 18
    • 0031037111 scopus 로고    scopus 로고
    • Regulation of adipose cell number in man
    • Prins, J. B., and O'Rahilly, S. (1997) Regulation of adipose cell number in man. Clin. Sci. (Lond.) 92, 3-11
    • (1997) Clin. Sci. (Lond.) , vol.92 , pp. 3-11
    • Prins, J.B.1    O'Rahilly, S.2
  • 21
    • 38349194472 scopus 로고    scopus 로고
    • Cell death in health and disease
    • Lockshin, R. A., and Zakeri, Z. (2007) Cell death in health and disease. J. Cell. Mol. Med. 11, 1214-1224
    • (2007) J. Cell. Mol. Med. , vol.11 , pp. 1214-1224
    • Lockshin, R.A.1    Zakeri, Z.2
  • 22
    • 33746886979 scopus 로고    scopus 로고
    • Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
    • Fulda, S., and Debatin, K. M. (2006) Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25, 4798-4811
    • (2006) Oncogene , vol.25 , pp. 4798-4811
    • Fulda, S.1    Debatin, K.M.2
  • 23
    • 44749085513 scopus 로고    scopus 로고
    • Targeting the extrinsic apoptosis pathway in cancer
    • Ashkenazi, A. (2008) Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev. 19, 325-331
    • (2008) Cytokine Growth Factor Rev. , vol.19 , pp. 325-331
    • Ashkenazi, A.1
  • 24
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • DOI 10.1152/physrev.00013.2006
    • Kroemer, G., Galluzzi, L., and Brenner, C. (2007) Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87, 99-163 (Pubitemid 46209992)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 25
    • 1642464824 scopus 로고    scopus 로고
    • Inhibition of death-receptor mediated apoptosis in human adipocytes by the insulin-like growth factor I (IGF-I)/IGF-I receptor autocrine circuit
    • Fischer-Posovszky, P., Tornqvist, H., Debatin, K. M., and Wabitsch, M. (2004) Inhibition of death-receptor mediated apoptosis in human adipocytes by the insulin-like growth factor I (IGF-I)/IGF-I receptor autocrine circuit. Endocrinology 145, 1849-1859
    • (2004) Endocrinology , vol.145 , pp. 1849-1859
    • Fischer-Posovszky, P.1    Tornqvist, H.2    Debatin, K.M.3    Wabitsch, M.4
  • 26
    • 55449097618 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes
    • Rayalam, S., Yang, J. Y., Ambati, S., Della-Fera, M. A., and Baile, C. A. (2008) Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes. Phytother. Res. 22, 1367-1371
    • (2008) Phytother. Res. , vol.22 , pp. 1367-1371
    • Rayalam, S.1    Yang, J.Y.2    Ambati, S.3    Della-Fera, M.A.4    Baile, C.A.5
  • 27
    • 42649130051 scopus 로고    scopus 로고
    • Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin
    • Yang, J. Y., Della-Fera, M. A., Rayalam, S., Ambati, S., Hartzell, D. L., Park, H. J., and Baile, C. A. (2008) Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin. Life Sci. 82, 1032-1039
    • (2008) Life Sci. , vol.82 , pp. 1032-1039
    • Yang, J.Y.1    Della-Fera, M.A.2    Rayalam, S.3    Ambati, S.4    Hartzell, D.L.5    Park, H.J.6    Baile, C.A.7
  • 28
    • 37149009308 scopus 로고    scopus 로고
    • Resveratrol potentiates genistein's antiadipogenic and proapoptotic effects in 3T3-L1 adipocytes
    • Rayalam, S., Della-Fera, M. A., Yang, J. Y., Park, H. J., Ambati, S., and Baile, C. A. (2007) Resveratrol potentiates genistein's antiadipogenic and proapoptotic effects in 3T3-L1 adipocytes. J. Nutr. 137, 2668-2673
    • (2007) J. Nutr. , vol.137 , pp. 2668-2673
    • Rayalam, S.1    Della-Fera, M.A.2    Yang, J.Y.3    Park, H.J.4    Ambati, S.5    Baile, C.A.6
  • 30
    • 36949021068 scopus 로고    scopus 로고
    • Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes
    • Bai, L., Pang, W. J., Yang, Y. J., and Yang, G. S. (2008) Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes. Mol. Cell. Biochem. 307, 129-140
    • (2008) Mol. Cell. Biochem. , vol.307 , pp. 129-140
    • Bai, L.1    Pang, W.J.2    Yang, Y.J.3    Yang, G.S.4
  • 31
    • 70349242054 scopus 로고    scopus 로고
    • The inhibitory effect of resveratrol on leptin secretion from rat adipocytes
    • Szkudelska, K., Nogowski, L., and Szkudelski, T. (2009) The inhibitory effect of resveratrol on leptin secretion from rat adipocytes. Eur J. Clin. Invest.
    • (2009) Eur J. Clin. Invest.
    • Szkudelska, K.1    Nogowski, L.2    Szkudelski, T.3
  • 32
    • 59849106498 scopus 로고    scopus 로고
    • Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the antilipolytic action of insulin in isolated rat adipocytes
    • Szkudelska, K., Nogowski, L., and Szkudelski, T. (2009) Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the antilipolytic action of insulin in isolated rat adipocytes. J. Steroid. Biochem. Mol. Biol. 113, 17-24
    • (2009) J. Steroid. Biochem. Mol. Biol. , vol.113 , pp. 17-24
    • Szkudelska, K.1    Nogowski, L.2    Szkudelski, T.3
  • 33
    • 57449103168 scopus 로고    scopus 로고
    • Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells
    • Backesjo, C. M., Li, Y., Lindgren, U., and Haldosen, L. A. (2009) Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. Cells Tissues Organs 189, 93-97
    • (2009) Cells Tissues Organs , vol.189 , pp. 93-97
    • Backesjo, C.M.1    Li, Y.2    Lindgren, U.3    Haldosen, L.A.4
  • 34
    • 44949129961 scopus 로고    scopus 로고
    • Modulation of peroxisome proliferator-activated receptor gamma stability and transcriptional activity in adipocytes by resveratrol
    • Floyd, Z. E., Wang, Z. Q., Kilroy, G., and Cefalu, W. T. (2008) Modulation of peroxisome proliferator-activated receptor gamma stability and transcriptional activity in adipocytes by resveratrol. Metabolism 57, S32-38
    • (2008) Metabolism , vol.57
    • Floyd, Z.E.1    Wang, Z.Q.2    Kilroy, G.3    Cefalu, W.T.4
  • 35
    • 46149101224 scopus 로고    scopus 로고
    • Curcumin and resveratrol inhibit nuclear factor-B-mediated cytokine expression in adipocytes
    • Gonzales, A. M., and Orlando, R. A. (2008) Curcumin and resveratrol inhibit nuclear factor-B-mediated cytokine expression in adipocytes. Nutr. Metab. (Lond.) 5, 17
    • (2008) Nutr. Metab. (Lond.) , vol.5 , pp. 17
    • Gonzales, A.M.1    Orlando, R.A.2
  • 36
    • 1642576201 scopus 로고    scopus 로고
    • Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol
    • Fulda, S., and Debatin, K. M. (2004) Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol. Cancer Res. 64, 337-346
    • (2004) Cancer Res. , vol.64 , pp. 337-346
    • Fulda, S.1    Debatin, K.M.2
  • 37
    • 4644327128 scopus 로고    scopus 로고
    • Sensitization for anticancer drug-induced apoptosis by the chemopreventive agent resveratrol
    • Fulda, S., and Debatin, K. M. (2004) Sensitization for anticancer drug-induced apoptosis by the chemopreventive agent resveratrol. Oncogene 23, 6702-6711
    • (2004) Oncogene , vol.23 , pp. 6702-6711
    • Fulda, S.1    Debatin, K.M.2
  • 38
    • 14844312113 scopus 로고    scopus 로고
    • Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling
    • Fulda, S., and Debatin, K.-M. (2005) Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling. Eur. J. Cancer 41, 786-798
    • (2005) Eur. J. Cancer , vol.41 , pp. 786-798
    • Fulda, S.1    Debatin, K.-M.2
  • 41
    • 0034473158 scopus 로고    scopus 로고
    • IGF-I- and IGFBP-3-expression in cultured human preadipocytes and adipocytes
    • Wabitsch, M., Heinze, E., Debatin, K. M., and Blum, W. F. (2000) IGF-I- and IGFBP-3-expression in cultured human preadipocytes and adipocytes. Horm. Metab. Res. 32, 555-559 (Pubitemid 32176086)
    • (2000) Hormone and Metabolic Research , vol.32 , Issue.11-12 , pp. 555-559
    • Wabitsch, M.1    Heinze, E.2    Debatin, K.-M.3    Blum, W.F.4
  • 42
    • 0030815250 scopus 로고    scopus 로고
    • Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors
    • Fulda, S., Friesen, C., Los, M., Scaffidi, C., Mier, W., Benedict, M., Nunez, G., Krammer, P. H., Peter, M. E., and Debatin, K. M. (1997) Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors. Cancer Res. 57, 4956-4964 (Pubitemid 27469008)
    • (1997) Cancer Research , vol.57 , Issue.21 , pp. 4956-4964
    • Fulda, S.1    Friesen, C.2    Los, M.3    Scaffidi, C.4    Mier, W.5    Benedict, M.6    Nunez, G.7    Krammer, P.H.8    Peter, M.E.9    Debatin, K.-M.10
  • 43
    • 33846491404 scopus 로고    scopus 로고
    • NF-κB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition
    • La Ferla-Bruhl, K., Westhoff, M. A., Karl, S., Kasperczyk, H., Zwacka, R. M., Debatin, K. M., and Fulda, S. (2007) NF-κB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition. Oncogene 26, 571-582
    • (2007) Oncogene , vol.26 , pp. 571-582
    • La Ferla-Bruhl, K.1    Westhoff, M.A.2    Karl, S.3    Kasperczyk, H.4    Zwacka, R.M.5    Debatin, K.M.6    Fulda, S.7
  • 44
    • 51049112961 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis
    • Opel, D., Westhoff, M. A., Bender, A., Braun, V., Debatin, K. M., and Fulda, S. (2008) Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis. Cancer Res. 68, 6271-6280
    • (2008) Cancer Res. , vol.68 , pp. 6271-6280
    • Opel, D.1    Westhoff, M.A.2    Bender, A.3    Braun, V.4    Debatin, K.M.5    Fulda, S.6
  • 45
    • 69849094949 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors cooperate with IFN-γ to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8
    • Häcker, S., Dittrich, A., Mohr, A., Schweitzer, T., Rutkowski, S., Krauss, J., Debatin, K. M., and Fulda, S. (2009) Histone deacetylase inhibitors cooperate with IFN-γ to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8. Oncogene 28, 3097-3110
    • (2009) Oncogene , vol.28 , pp. 3097-3110
    • Häcker, S.1    Dittrich, A.2    Mohr, A.3    Schweitzer, T.4    Rutkowski, S.5    Krauss, J.6    Debatin, K.M.7    Fulda, S.8
  • 46
    • 54249159248 scopus 로고    scopus 로고
    • Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo
    • Vogler, M., Walczak, H., Stadel, D., Haas, T. L., Genze, F., Jovanovic, M., Gschwend, J. E., Simmet, T., Debatin, K. M., and Fulda, S. (2008) Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo. Cancer Res. 68, 7956-7965
    • (2008) Cancer Res. , vol.68 , pp. 7956-7965
    • Vogler, M.1    Walczak, H.2    Stadel, D.3    Haas, T.L.4    Genze, F.5    Jovanovic, M.6    Gschwend, J.E.7    Simmet, T.8    Debatin, K.M.9    Fulda, S.10
  • 47
    • 0002658306 scopus 로고
    • The median-effect principle and the combination index for quantitation of synergism and antagonism
    • Chou, T. C., ed Academic Press, San Diego, CA, USA
    • Chou, T. C. (1991) The median-effect principle and the combination index for quantitation of synergism and antagonism. In Synergism and Antagonism in Chemotherapy (Chou, T. C., ed) pp. 61-102, Academic Press, San Diego, CA, USA
    • (1991) Synergism and Antagonism in Chemotherapy , pp. 61-102
    • Chou, T.C.1
  • 48
    • 67649386107 scopus 로고    scopus 로고
    • Life and death by death receptors
    • Guicciardi, M. E., and Gores, G. J. (2009) Life and death by death receptors. FASEB J. 23, 1625-1637
    • (2009) FASEB J. , vol.23 , pp. 1625-1637
    • Guicciardi, M.E.1    Gores, G.J.2
  • 49
    • 34250331231 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis
    • Kohlhaas, S. L., Craxton, A., Sun, X. M., Pinkoski, M. J., and Cohen, G. M. (2007) Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. J. Biol. Chem. 282, 12831-12841
    • (2007) J. Biol. Chem. , vol.282 , pp. 12831-12841
    • Kohlhaas, S.L.1    Craxton, A.2    Sun, X.M.3    Pinkoski, M.J.4    Cohen, G.M.5
  • 50
    • 37549036729 scopus 로고    scopus 로고
    • Survivin, cancer networks and pathway-directed drug discovery
    • Altieri, D. C. (2008) Survivin, cancer networks and pathway-directed drug discovery. Nat. Rev. Cancer 8, 61-70
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 61-70
    • Altieri, D.C.1
  • 53
    • 10644246821 scopus 로고    scopus 로고
    • Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
    • Delmas, D., Rebe, C., Micheau, O., Athias, A., Gambert, P., Grazide, S., Laurent, G., Latruffe, N., and Solary, E. (2004) Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene 23, 8979-8986
    • (2004) Oncogene , vol.23 , pp. 8979-8986
    • Delmas, D.1    Rebe, C.2    Micheau, O.3    Athias, A.4    Gambert, P.5    Grazide, S.6    Laurent, G.7    Latruffe, N.8    Solary, E.9
  • 55
    • 39549088497 scopus 로고    scopus 로고
    • Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression
    • Ivanov, V. N., Partridge, M. A., Johnson, G. E., Huang, S. X., Zhou, H., and Hei, T. K. (2008) Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression. Exp. Cell. Res. 314, 1163-1176
    • (2008) Exp. Cell. Res. , vol.314 , pp. 1163-1176
    • Ivanov, V.N.1    Partridge, M.A.2    Johnson, G.E.3    Huang, S.X.4    Zhou, H.5    Hei, T.K.6
  • 56
    • 35648975568 scopus 로고    scopus 로고
    • Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms
    • Gill, C., Walsh, S. E., Morrissey, C., Fitzpatrick, J. M., and Watson, R. W. G. (2007) Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms. Prostate 67, 1641-1653
    • (2007) Prostate , vol.67 , pp. 1641-1653
    • Gill, C.1    Walsh, S.E.2    Morrissey, C.3    Fitzpatrick, J.M.4    Watson, R.W.G.5
  • 57
    • 36448992018 scopus 로고    scopus 로고
    • Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4′, 5 tri-hydroxystilbene): Molecular mechanisms and therapeutic potential
    • Shankar, S., Chen, Q., Siddiqui, I., Sarva, K., and Srivastava, R. K. (2007) Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4′, 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential. J. Mol. Signal. 2, 7
    • (2007) J. Mol. Signal. , vol.2 , pp. 7
    • Shankar, S.1    Chen, Q.2    Siddiqui, I.3    Sarva, K.4    Srivastava, R.K.5
  • 58
    • 34648813877 scopus 로고    scopus 로고
    • Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells
    • Shankar, S., Siddiqui, I., and Srivastava, R. K. (2007) Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells. Mol. Cell. Biochem. 304, 273-285
    • (2007) Mol. Cell. Biochem. , vol.304 , pp. 273-285
    • Shankar, S.1    Siddiqui, I.2    Srivastava, R.K.3
  • 62
    • 11144251691 scopus 로고    scopus 로고
    • Associations of serum TRAIL concentrations, anthropometric variables, and serum lipid parameters in healthy adults
    • Choi, J. W., Song, J. S., and Pai, S. H. (2004) Associations of serum TRAIL concentrations, anthropometric variables, and serum lipid parameters in healthy adults. Ann. Clin. Lab. Sci. 34, 400-404
    • (2004) Ann. Clin. Lab. Sci. , vol.34 , pp. 400-404
    • Choi, J.W.1    Song, J.S.2    Pai, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.