Progranulin deficiency promotes post-ischemic blood-brain barrier disruption

Journal of Neuroscience

Volumn 33, Issue 50, 2013, Pages 19579-19589

  Jackman, Katherine ^a   Kahles, Timo ^a   Lane, Diane ^a   Garcia Bonilla, Lidia ^a   Abe, Takato ^a   Capone, Carmen ^a   Hochrainer, Karin ^a   Voss, Henning ^b   Zhou, Ping ^a   Ding, Aihao ^b   Anrather, Josef ^a   Iadecola, Costantino ^a  

^a FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Blood brain barrier; Frontotemporal dementia; Neurovascular unit; Progranulin; Stroke

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR C; PROGRANULIN; RANTES; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TIGHT JUNCTION PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENCEPHALITIS; ENDOTHELIUM CELL; FLOW CYTOMETRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY;

BLOOD-BRAIN BARRIER; FRONTOTEMPORAL DEMENTIA; NEUROVASCULAR UNIT; PROGRANULIN; STROKE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; ENDOTHELIAL CELLS; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, KNOCKOUT; REPERFUSION INJURY; STROKE;

EID: 84889794517     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4318-13.2013     Document Type: Article

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