-
1
-
-
77954578417
-
Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging
-
20522652 1:CAS:528:DC%2BC3cXpslCrs7g%3D 10.2353/ajpath.2010.090915
-
Z Ahmed H Sheng Y-F Xu, et al. 2010 Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging Am J Pathol 177 311 324 20522652 1:CAS:528:DC%2BC3cXpslCrs7g%3D 10.2353/ajpath.2010.090915
-
(2010)
Am J Pathol
, vol.177
, pp. 311-324
-
-
Ahmed, Z.1
Sheng, H.2
Xu, Y.-F.3
-
2
-
-
0025248770
-
Acrosome biogenesis begins during meiosis: Evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesis
-
1692485 1:CAS:528:DyaK3cXitFCgu74%3D 10.1095/biolreprod42.2.317
-
OO Anakwe GL Gerton 1990 Acrosome biogenesis begins during meiosis: evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesis Biol Reprod 42 317 328 1692485 1:CAS:528:DyaK3cXitFCgu74%3D 10.1095/biolreprod42.2.317
-
(1990)
Biol Reprod
, vol.42
, pp. 317-328
-
-
Anakwe, O.O.1
Gerton, G.L.2
-
3
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
17084815 1:CAS:528:DC%2BD28Xht1SmsbbJ 10.1016/j.bbrc.2006.10.093
-
T Arai M Hasegawa H Akiyama, et al. 2006 TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Biochem Biophys Res Commun 351 602 611 17084815 1:CAS:528:DC%2BD28Xht1SmsbbJ 10.1016/j.bbrc.2006.10.093
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
-
4
-
-
0033787069
-
Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing
-
11017147 1:CAS:528:DC%2BD3cXntlKnurc%3D 10.1038/80489
-
GS Ashcroft K Lei W Jin, et al. 2000 Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing Nat Med 6 1147 1153 11017147 1:CAS:528:DC%2BD3cXntlKnurc%3D 10.1038/80489
-
(2000)
Nat Med
, vol.6
, pp. 1147-1153
-
-
Ashcroft, G.S.1
Lei, K.2
Jin, W.3
-
5
-
-
67651207673
-
ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor
-
19487464 1:CAS:528:DC%2BD1MXptFehtro%3D 10.1128/MCB.00056-09
-
X-H Bai D-W Wang L Kong, et al. 2009 ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor Mol Cell Biol 29 4201 4219 19487464 1:CAS:528:DC%2BD1MXptFehtro%3D 10.1128/MCB.00056-09
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4201-4219
-
-
Bai, X.-H.1
Wang, D.-W.2
Kong, L.3
-
6
-
-
0037457875
-
Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease
-
12525699 1:CAS:528:DC%2BD3sXnvVKltA%3D%3D 10.1073/pnas.0237313100
-
CA Baker L Manuelidis 2003 Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease Proc Natl Acad Sci 100 675 679 12525699 1:CAS:528:DC%2BD3sXnvVKltA%3D%3D 10.1073/pnas.0237313100
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 675-679
-
-
Baker, C.A.1
Manuelidis, L.2
-
7
-
-
33746919083
-
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
-
16862116 1:CAS:528:DC%2BD28XosVOgurc%3D 10.1038/nature05016
-
M Baker IR Mackenzie SM Pickering-Brown, et al. 2006 Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 Nature 442 916 919 16862116 1:CAS:528:DC%2BD28XosVOgurc%3D 10.1038/nature05016
-
(2006)
Nature
, vol.442
, pp. 916-919
-
-
Baker, M.1
MacKenzie, I.R.2
Pickering-Brown, S.M.3
-
8
-
-
0036295562
-
The EGF-like homeotic protein dlk affects cell growth and interacts with growth-modulating molecules in the yeast two-hybrid system
-
11846389 10.1006/bbrc.2002.6431 1:CAS:528:DC%2BD38Xht1Ggtrs%3D
-
V Baladrón MJ Ruiz-Hidalgo E Bonvini E Gubina V Notario J Laborda 2002 The EGF-like homeotic protein dlk affects cell growth and interacts with growth-modulating molecules in the yeast two-hybrid system Biochem Biophys Res Commun 291 193 204 11846389 10.1006/bbrc.2002.6431 1:CAS:528: DC%2BD38Xht1Ggtrs%3D
-
(2002)
Biochem Biophys Res Commun
, vol.291
, pp. 193-204
-
-
Baladrón, V.1
Ruiz-Hidalgo, M.J.2
Bonvini, E.3
Gubina, E.4
Notario, V.5
Laborda, J.6
-
9
-
-
34547734976
-
The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection
-
17664292 1:CAS:528:DC%2BD2sXptVyjsLc%3D 10.1084/jem.20070494
-
C Benarafa GP Priebe E Remold-O'Donnell 2007 The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection J Exp Med 204 1901 1909 17664292 1:CAS:528: DC%2BD2sXptVyjsLc%3D 10.1084/jem.20070494
-
(2007)
J Exp Med
, vol.204
, pp. 1901-1909
-
-
Benarafa, C.1
Priebe, G.P.2
Remold-O'Donnell, E.3
-
10
-
-
0026457912
-
Structure and chromosomal location of the human granulin gene
-
1417868 1:CAS:528:DyaK3sXlslCqu7c%3D 10.1016/0006-291X(92)92349-3
-
V Bhandari A Bateman 1992 Structure and chromosomal location of the human granulin gene Biochem Biophys Res Commun 188 57 63 1417868 1:CAS:528: DyaK3sXlslCqu7c%3D 10.1016/0006-291X(92)92349-3
-
(1992)
Biochem Biophys Res Commun
, vol.188
, pp. 57-63
-
-
Bhandari, V.1
Bateman, A.2
-
11
-
-
0026580016
-
Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains
-
1542665 1:CAS:528:DyaK3sXhvV2ltrg%3D 10.1073/pnas.89.5.1715
-
V Bhandari RG Palfree A Bateman 1992 Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains Proc Natl Acad Sci 89 1715 1719 1542665 1:CAS:528: DyaK3sXhvV2ltrg%3D 10.1073/pnas.89.5.1715
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 1715-1719
-
-
Bhandari, V.1
Palfree, R.G.2
Bateman, A.3
-
12
-
-
47949123468
-
Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: Dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding
-
18505826 1:CAS:528:DC%2BD1cXptF2luro%3D 10.1128/MCB.01775-07
-
GS Butler RA Dean EM Tam CM Overall 2008 Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding Mol Cell Biol 28 4896 4914 18505826 1:CAS:528:DC%2BD1cXptF2luro%3D 10.1128/MCB.01775-07
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4896-4914
-
-
Butler, G.S.1
Dean, R.A.2
Tam, E.M.3
Overall, C.M.4
-
13
-
-
78650535968
-
GEP, a local growth factor, is critical for odontogenesis and amelogenesis
-
21152114 1:CAS:528:DC%2BC3cXhsFWkt7zO
-
Z Cao B Jiang Y Xie C-J Liu JQ Feng 2010 GEP, a local growth factor, is critical for odontogenesis and amelogenesis Int J Biol Sci 6 719 729 21152114 1:CAS:528:DC%2BC3cXhsFWkt7zO
-
(2010)
Int J Biol Sci
, vol.6
, pp. 719-729
-
-
Cao, Z.1
Jiang, B.2
Xie, Y.3
Liu, C.-J.4
Feng, J.Q.5
-
14
-
-
78649796276
-
Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma
-
21087763 1:CAS:528:DC%2BC3cXhsFags7fJ 10.1016/j.ajhg.2010.11.002
-
MM Carrasquillo AM Nicholson N Finch, et al. 2010 Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma Am J Hum Genet 87 890 897 21087763 1:CAS:528:DC%2BC3cXhsFags7fJ 10.1016/j.ajhg.2010.11.002
-
(2010)
Am J Hum Genet
, vol.87
, pp. 890-897
-
-
Carrasquillo, M.M.1
Nicholson, A.M.2
Finch, N.3
-
15
-
-
51149096388
-
Expression of PC cell-derived growth factor and vascular endothelial growth factor in esophageal squamous cell carcinoma and their clinicopathologic significance
-
18706200 1:CAS:528:DC%2BD1cXnslGqtr4%3D
-
X-Y Chen J-S Li Q-P Liang D-Z He J Zhao 2008 Expression of PC cell-derived growth factor and vascular endothelial growth factor in esophageal squamous cell carcinoma and their clinicopathologic significance Chin Med J 121 881 886 18706200 1:CAS:528:DC%2BD1cXnslGqtr4%3D
-
(2008)
Chin Med J
, vol.121
, pp. 881-886
-
-
Chen, X.-Y.1
Li, J.-S.2
Liang, Q.-P.3
He, D.-Z.4
Zhao, J.5
-
16
-
-
77950867149
-
TAR DNA-binding protein 43 in neurodegenerative disease
-
20234357 1:CAS:528:DC%2BC3cXksVehurc%3D 10.1038/nrneurol.2010.18
-
AS Chen-Plotkin VMY Lee JQ Trojanowski 2010 TAR DNA-binding protein 43 in neurodegenerative disease Nat Rev Neurol 6 211 220 20234357 1:CAS:528:DC%2BC3cXksVehurc%3D 10.1038/nrneurol.2010.18
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 211-220
-
-
Chen-Plotkin, A.S.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
-
17
-
-
9344229795
-
Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma
-
15569995 1:CAS:528:DC%2BD2cXhtVanurzJ 10.1158/1078-0432.CCR-04-0960
-
ST Cheung SY Wong KL Leung, et al. 2004 Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma Clin Cancer Res 10 7629 7636 15569995 1:CAS:528:DC%2BD2cXhtVanurzJ 10.1158/1078-0432.CCR-04-0960
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7629-7636
-
-
Cheung, S.T.1
Wong, S.Y.2
Leung, K.L.3
-
18
-
-
39049195644
-
GEP associates with wild-type p53 in hepatocellular carcinoma
-
16685387 1:CAS:528:DC%2BD28XlvVOis7s%3D
-
ST Cheung SY Wong YT Lee ST Fan 2006 GEP associates with wild-type p53 in hepatocellular carcinoma Oncol Rep 15 1507 1511 16685387 1:CAS:528: DC%2BD28XlvVOis7s%3D
-
(2006)
Oncol Rep
, vol.15
, pp. 1507-1511
-
-
Cheung, S.T.1
Wong, S.Y.2
Lee, Y.T.3
Fan, S.T.4
-
19
-
-
78650511134
-
Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance
-
20682318 1:CAS:528:DC%2BC3cXhsFyltLnL 10.1053/j.gastro.2010.07.049
-
ST Cheung PFY Cheung CKC Cheng NCL Wong ST Fan 2011 Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance Gastroenterology 140 344 355 20682318 1:CAS:528: DC%2BC3cXhsFyltLnL 10.1053/j.gastro.2010.07.049
-
(2011)
Gastroenterology
, vol.140
, pp. 344-355
-
-
Cheung, S.T.1
Cheung, P.F.Y.2
Cheng, C.K.C.3
Wong, N.C.L.4
Fan, S.T.5
-
20
-
-
77957818067
-
Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of survival motor neuron 1
-
20946666 10.1186/1750-1326-5-41 1:CAS:528:DC%2BC3cXhtlamsbbF
-
BP Chitramuthu DC Baranowski DG Kay A Bateman HP Bennett 2010 Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of survival motor neuron 1 Mol Neurodegener 5 41 20946666 10.1186/1750-1326-5-41 1:CAS:528:DC%2BC3cXhtlamsbbF
-
(2010)
Mol Neurodegener
, vol.5
, pp. 41
-
-
Chitramuthu, B.P.1
Baranowski, D.C.2
Kay, D.G.3
Bateman, A.4
Bennett, H.P.5
-
21
-
-
48949093046
-
Gene expression study on peripheral blood identifies progranulin mutations
-
18551524 1:CAS:528:DC%2BD1cXhtVKnsrnK 10.1002/ana.21397
-
G Coppola A Karyda R Rademakers, et al. 2008 Gene expression study on peripheral blood identifies progranulin mutations Ann Neurol 64 92 96 18551524 1:CAS:528:DC%2BD1cXhtVKnsrnK 10.1002/ana.21397
-
(2008)
Ann Neurol
, vol.64
, pp. 92-96
-
-
Coppola, G.1
Karyda, A.2
Rademakers, R.3
-
22
-
-
67651091752
-
Cortical atrophy and language network reorganization associated with a novel progranulin mutation
-
19020205 10.1093/cercor/bhn202
-
C Cruchaga MA Fernández-Seara M Seijo-Martínez, et al. 2009 Cortical atrophy and language network reorganization associated with a novel progranulin mutation Cereb Cortex 19 1751 1760 19020205 10.1093/cercor/bhn202
-
(2009)
Cereb Cortex
, vol.19
, pp. 1751-1760
-
-
Cruchaga, C.1
Fernández-Seara, M.A.2
Seijo-Martínez, M.3
-
23
-
-
33746910649
-
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
-
16862115 1:CAS:528:DC%2BD28XosVOgu74%3D 10.1038/nature05017
-
M Cruts I Gijselinck J van der Zee, et al. 2006 Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 Nature 442 920 924 16862115 1:CAS:528:DC%2BD28XosVOgu74%3D 10.1038/nature05017
-
(2006)
Nature
, vol.442
, pp. 920-924
-
-
Cruts, M.1
Gijselinck, I.2
Van Der Zee, J.3
-
24
-
-
0027215753
-
Biochemical analysis of the epithelin receptor
-
8387520 1:CAS:528:DyaK3sXktVWktr4%3D
-
JM Culouscou GW Carlton M Shoyab 1993 Biochemical analysis of the epithelin receptor J Biol Chem 268 10458 10462 8387520 1:CAS:528: DyaK3sXktVWktr4%3D
-
(1993)
J Biol Chem
, vol.268
, pp. 10458-10462
-
-
Culouscou, J.M.1
Carlton, G.W.2
Shoyab, M.3
-
25
-
-
0033917655
-
Cellular localization of gene expression for progranulin
-
10858277 1:CAS:528:DC%2BD3cXksFyjtLY%3D 10.1177/002215540004800713
-
R Daniel Z He KP Carmichael J Halper A Bateman 2000 Cellular localization of gene expression for progranulin J Histochem Cytochem 48 999 1009 10858277 1:CAS:528:DC%2BD3cXksFyjtLY%3D 10.1177/002215540004800713
-
(2000)
J Histochem Cytochem
, vol.48
, pp. 999-1009
-
-
Daniel, R.1
He, Z.2
Carmichael, K.P.3
Halper, J.4
Bateman, A.5
-
26
-
-
0042635680
-
Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development
-
12889069 1:CAS:528:DC%2BD3sXntVyhsLw%3D 10.1002/dvdy.10341
-
R Daniel E Daniels Z He A Bateman 2003 Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development Dev Dyn 227 593 599 12889069 1:CAS:528:DC%2BD3sXntVyhsLw%3D 10.1002/dvdy.10341
-
(2003)
Dev Dyn
, vol.227
, pp. 593-599
-
-
Daniel, R.1
Daniels, E.2
He, Z.3
Bateman, A.4
-
27
-
-
0342980940
-
Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor)
-
10625564 10.1006/dbio.1999.9564 1:CAS:528:DC%2BD3cXhs1Wqsw%3D%3D
-
L Díaz-Cueto P Stein A Jacobs RM Schultz GL Gerton 2000 Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor) Dev Biol 217 406 418 10625564 10.1006/dbio.1999.9564 1:CAS:528:DC%2BD3cXhs1Wqsw%3D%3D
-
(2000)
Dev Biol
, vol.217
, pp. 406-418
-
-
Díaz-Cueto, L.1
Stein, P.2
Jacobs, A.3
Schultz, R.M.4
Gerton, G.L.5
-
28
-
-
67650432367
-
Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin
-
19522733 1:CAS:528:DC%2BD1MXptlensb8%3D 10.1111/j.1471-4159.2009.06211.x
-
D Dormann A Capell AM Carlson, et al. 2009 Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin J Neurochem 110 1082 1094 19522733 1:CAS:528:DC%2BD1MXptlensb8%3D 10.1111/j.1471-4159.2009.06211.x
-
(2009)
J Neurochem
, vol.110
, pp. 1082-1094
-
-
Dormann, D.1
Capell, A.2
Carlson, A.M.3
-
29
-
-
79551519982
-
Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice
-
21266779 1:CAS:528:DC%2BC3MXhsl2qsrc%3D 10.1172/JCI43757
-
M Elkabets AM Gifford C Scheel, et al. 2011 Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice J Clin Invest 121 784 799 21266779 1:CAS:528:DC%2BC3MXhsl2qsrc%3D 10.1172/JCI43757
-
(2011)
J Clin Invest
, vol.121
, pp. 784-799
-
-
Elkabets, M.1
Gifford, A.M.2
Scheel, C.3
-
30
-
-
77953530644
-
Granulin epithelin precursor: A bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis
-
20124436 1:CAS:528:DC%2BC3cXnt1Oju7g%3D 10.1096/fj.09-144659
-
JQ Feng F-J Guo B-C Jiang, et al. 2010 Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis FASEB J 24 1879 1892 20124436 1:CAS:528:DC%2BC3cXnt1Oju7g%3D 10.1096/fj.09-144659
-
(2010)
FASEB J
, vol.24
, pp. 1879-1892
-
-
Feng, J.Q.1
Guo, F.-J.2
Jiang, B.-C.3
-
31
-
-
64849103956
-
Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members
-
19158106 10.1093/brain/awn352
-
N Finch M Baker R Crook, et al. 2009 Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members Brain 132 583 591 19158106 10.1093/brain/awn352
-
(2009)
Brain
, vol.132
, pp. 583-591
-
-
Finch, N.1
Baker, M.2
Crook, R.3
-
32
-
-
79953221473
-
Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β
-
21204008 1:CAS:528:DC%2BC3cXoslelt70%3D 10.1007/s13238-010-0067-1
-
X Gao AP Joselin L Wang, et al. 2010 Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β Protein Cell 1 552 562 21204008 1:CAS:528:DC%2BC3cXoslelt70%3D 10.1007/s13238-010-0067-1
-
(2010)
Protein Cell
, vol.1
, pp. 552-562
-
-
Gao, X.1
Joselin, A.P.2
Wang, L.3
-
33
-
-
54449085260
-
Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration
-
18768919 1:CAS:528:DC%2BD1cXht1SntLfF 10.1212/01.wnl.0000325058.10218.fc
-
R Ghidoni L Benussi M Glionna M Franzoni G Binetti 2008 Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration Neurology 71 1235 1239 18768919 1:CAS:528:DC%2BD1cXht1SntLfF 10.1212/01.wnl.0000325058.10218.fc
-
(2008)
Neurology
, vol.71
, pp. 1235-1239
-
-
Ghidoni, R.1
Benussi, L.2
Glionna, M.3
Franzoni, M.4
Binetti, G.5
-
34
-
-
0141755382
-
A novel interaction between perlecan protein core and progranulin-potential effects on tumor growth
-
12900424 1:CAS:528:DC%2BD3sXnslSqtr0%3D 10.1074/jbc.C300310200
-
E Gonzalez M Mongiat S Slater R Baffa R Iozzo 2003 A novel interaction between perlecan protein core and progranulin-potential effects on tumor growth J Biol Chem 278 38113 38116 12900424 1:CAS:528:DC%2BD3sXnslSqtr0%3D 10.1074/jbc.C300310200
-
(2003)
J Biol Chem
, vol.278
, pp. 38113-38116
-
-
Gonzalez, E.1
Mongiat, M.2
Slater, S.3
Baffa, R.4
Iozzo, R.5
-
35
-
-
37549049344
-
Progranulin is a stress-response factor in fibroblasts subjected to hypoxia and acidosis
-
18092235 1:CAS:528:DC%2BD2sXhsVCgsbnK 10.1080/08977190701781222
-
RR Guerra L Kriazhev FJ Hernandez-Blazquez A Bateman 2007 Progranulin is a stress-response factor in fibroblasts subjected to hypoxia and acidosis Growth Factors 25 280 285 18092235 1:CAS:528:DC%2BD2sXhsVCgsbnK 10.1080/ 08977190701781222
-
(2007)
Growth Factors
, vol.25
, pp. 280-285
-
-
Guerra, R.R.1
Kriazhev, L.2
Hernandez-Blazquez, F.J.3
Bateman, A.4
-
36
-
-
77954222578
-
Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix protein
-
20506400 1:CAS:528:DC%2BC3cXht1aqsLzP
-
F Guo Y Lai Q Tian EA Lin L Kong C Liu 2010 Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix protein Arthritis Rheum 62 2023 2036 20506400 1:CAS:528:DC%2BC3cXht1aqsLzP
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2023-2036
-
-
Guo, F.1
Lai, Y.2
Tian, Q.3
Lin, E.A.4
Kong, L.5
Liu, C.6
-
37
-
-
78649904881
-
Progranulin is a potential prognostic biomarker in advanced epithelial ovarian cancers
-
20950846 1:CAS:528:DC%2BC3cXhsFWqtb3P 10.1016/j.ygyno.2010.09.006
-
JJ Han M Yu N Houston SM Steinberg EC Kohn 2011 Progranulin is a potential prognostic biomarker in advanced epithelial ovarian cancers Gynecol Oncol 120 5 10 20950846 1:CAS:528:DC%2BC3cXhsFWqtb3P 10.1016/j.ygyno.2010.09.006
-
(2011)
Gynecol Oncol
, vol.120
, pp. 5-10
-
-
Han, J.J.1
Yu, M.2
Houston, N.3
Steinberg, S.M.4
Kohn, E.C.5
-
38
-
-
0033168521
-
Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo
-
10397269 1:CAS:528:DyaK1MXksVGjsrw%3D
-
Z He A Bateman 1999 Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo Cancer Res 59 3222 3229 10397269 1:CAS:528:DyaK1MXksVGjsrw%3D
-
(1999)
Cancer Res
, vol.59
, pp. 3222-3229
-
-
He, Z.1
Bateman, A.2
-
39
-
-
0242320195
-
Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis
-
12928786 1:CAS:528:DC%2BD3sXotVars7o%3D 10.1007/s00109-003-0474-3
-
Z He A Bateman 2003 Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis J Mol Med 81 600 612 12928786 1:CAS:528:DC%2BD3sXotVars7o%3D 10.1007/s00109-003-0474-3
-
(2003)
J Mol Med
, vol.81
, pp. 600-612
-
-
He, Z.1
Bateman, A.2
-
40
-
-
0036792137
-
Progranulin (PC-cell-derived growth factor/acrogranin) regulates invasion and cell survival
-
12359772 1:CAS:528:DC%2BD38Xnsl2lsbg%3D
-
Z He A Ismail L Kriazhev G Sadvakassova A Bateman 2002 Progranulin (PC-cell-derived growth factor/acrogranin) regulates invasion and cell survival Cancer Res 62 5590 5596 12359772 1:CAS:528:DC%2BD38Xnsl2lsbg%3D
-
(2002)
Cancer Res
, vol.62
, pp. 5590-5596
-
-
He, Z.1
Ismail, A.2
Kriazhev, L.3
Sadvakassova, G.4
Bateman, A.5
-
41
-
-
0037329891
-
Progranulin is a mediator of the wound response
-
12524533 1:CAS:528:DC%2BD3sXotlShtQ%3D%3D 10.1038/nm816
-
Z He CHP Ong J Halper A Bateman 2003 Progranulin is a mediator of the wound response Nat Med 9 225 229 12524533 1:CAS:528:DC%2BD3sXotlShtQ%3D%3D 10.1038/nm816
-
(2003)
Nat Med
, vol.9
, pp. 225-229
-
-
He, Z.1
Ong, C.H.P.2
Halper, J.3
Bateman, A.4
-
42
-
-
43949142502
-
Granulin-epithelin precursor as a therapeutic target for hepatocellular carcinoma
-
18393387 1:CAS:528:DC%2BD1cXmvVChs7g%3D 10.1002/hep.22191
-
JC Ho YC Ip ST Cheung, et al. 2008 Granulin-epithelin precursor as a therapeutic target for hepatocellular carcinoma Hepatology 47 1524 1532 18393387 1:CAS:528:DC%2BD1cXmvVChs7g%3D 10.1002/hep.22191
-
(2008)
Hepatology
, vol.47
, pp. 1524-1532
-
-
Ho, J.C.1
Ip, Y.C.2
Cheung, S.T.3
-
43
-
-
0037371643
-
The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription
-
12588988 1:CAS:528:DC%2BD3sXhs1Sgs78%3D 10.1128/MCB.23.5.1688-1702.2003
-
M Hoque TM Young C-G Lee G Serrero MB Mathews T Pe'ery 2003 The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription Mol Cell Biol 23 1688 1702 12588988 1:CAS:528:DC%2BD3sXhs1Sgs78%3D 10.1128/MCB.23.5.1688-1702.2003
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1688-1702
-
-
Hoque, M.1
Young, T.M.2
Lee, C.-G.3
Serrero, G.4
Mathews, M.B.5
Pe'Ery, T.6
-
44
-
-
17144430455
-
Granulin and granulin repeats interact with the Tat.P-TEFb complex and inhibit Tat transactivation
-
15653695 1:CAS:528:DC%2BD2MXivV2ktLg%3D 10.1074/jbc.M409575200
-
M Hoque B Tian MB Mathews T Pe'ery 2005 Granulin and granulin repeats interact with the Tat.P-TEFb complex and inhibit Tat transactivation J Biol Chem 280 13648 13657 15653695 1:CAS:528:DC%2BD2MXivV2ktLg%3D 10.1074/jbc.M409575200
-
(2005)
J Biol Chem
, vol.280
, pp. 13648-13657
-
-
Hoque, M.1
Tian, B.2
Mathews, M.B.3
Pe'Ery, T.4
-
45
-
-
75749109793
-
Progranulin (granulin/epithelin precursor) and its constituent granulin repeats repress transcription from cellular promoters
-
20054825 1:CAS:528:DC%2BC3cXhtlSitbw%3D
-
M Hoque MB Mathews T Pe'ery 2010 Progranulin (granulin/epithelin precursor) and its constituent granulin repeats repress transcription from cellular promoters J Cell Physiol 223 224 233 20054825 1:CAS:528: DC%2BC3cXhtlSitbw%3D
-
(2010)
J Cell Physiol
, vol.223
, pp. 224-233
-
-
Hoque, M.1
Mathews, M.B.2
Pe'Ery, T.3
-
46
-
-
0029780955
-
The hairpin stack fold, a novel protein architecture for a new family of protein growth factors
-
8784346 1:CAS:528:DyaK28XlsFyktLc%3D 10.1038/nsb0996-747
-
R Hrabal Z Chen S James HP Bennett F Ni 1996 The hairpin stack fold, a novel protein architecture for a new family of protein growth factors Nat Struct Biol 3 747 752 8784346 1:CAS:528:DyaK28XlsFyktLc%3D 10.1038/nsb0996-747
-
(1996)
Nat Struct Biol
, vol.3
, pp. 747-752
-
-
Hrabal, R.1
Chen, Z.2
James, S.3
Bennett, H.P.4
Ni, F.5
-
47
-
-
78449286213
-
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin
-
21092856 1:CAS:528:DC%2BC3cXhsVGntb3E 10.1016/j.neuron.2010.09.034
-
F Hu T Padukkavidana CB Vægter, et al. 2010 Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin Neuron 68 654 667 21092856 1:CAS:528:DC%2BC3cXhsVGntb3E 10.1016/j.neuron.2010.09.034
-
(2010)
Neuron
, vol.68
, pp. 654-667
-
-
Hu, F.1
Padukkavidana, T.2
Vægter, C.B.3
-
48
-
-
0034797275
-
Identification of genes involved in the host response to neurovirulent alphavirus infection
-
11581411 1:CAS:528:DC%2BD3MXns1Whtb8%3D 10.1128/JVI.75.21.10431-10445. 2001
-
C Johnston W Jiang T Chu B Levine 2001 Identification of genes involved in the host response to neurovirulent alphavirus infection J Virol 75 10431 10445 11581411 1:CAS:528:DC%2BD3MXns1Whtb8%3D 10.1128/JVI.75.21.10431-10445.2001
-
(2001)
J Virol
, vol.75
, pp. 10431-10445
-
-
Johnston, C.1
Jiang, W.2
Chu, T.3
Levine, B.4
-
49
-
-
12244281813
-
The granulin-epithelin precursor/PC-cell-derived growth factor is a growth factor for epithelial ovarian cancer
-
12538450 1:CAS:528:DC%2BD3sXnt1yjsg%3D%3D
-
MB Jones CM Michener JO Blanchette, et al. 2003 The granulin-epithelin precursor/PC-cell-derived growth factor is a growth factor for epithelial ovarian cancer Clin Cancer Res 9 44 51 12538450 1:CAS:528:DC%2BD3sXnt1yjsg%3D%3D
-
(2003)
Clin Cancer Res
, vol.9
, pp. 44-51
-
-
Jones, M.B.1
Michener, C.M.2
Blanchette, J.O.3
-
50
-
-
79952712455
-
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
-
21368173 1:CAS:528:DC%2BC3MXisFOht74%3D 10.1073/pnas.1100650108
-
AW Kao RJ Eisenhut LH Martens, et al. 2011 A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells Proc Natl Acad Sci 108 4441 4446 21368173 1:CAS:528:DC%2BC3MXisFOht74%3D 10.1073/pnas.1100650108
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 4441-4446
-
-
Kao, A.W.1
Eisenhut, R.J.2
Martens, L.H.3
-
51
-
-
58649098755
-
Progranulin, a secreted tumorigenesis and dementia-related factor, regulates mouse hair growth
-
19091514 1:CAS:528:DC%2BD1MXhtlKlurg%3D 10.1016/j.jdermsci.2008.10.002
-
M Kato N Hasunuma R Nakayama, et al. 2009 Progranulin, a secreted tumorigenesis and dementia-related factor, regulates mouse hair growth J Dermatol Sci 53 234 236 19091514 1:CAS:528:DC%2BD1MXhtlKlurg%3D 10.1016/j.jdermsci.2008.10.002
-
(2009)
J Dermatol Sci
, vol.53
, pp. 234-236
-
-
Kato, M.1
Hasunuma, N.2
Nakayama, R.3
-
52
-
-
46749083014
-
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin
-
18568075 1:CAS:528:DC%2BD1cXot1Ontrc%3D
-
K Kessenbrock L Fröhlich M Sixt, et al. 2008 Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin J Clin Invest 118 2438 2447 18568075 1:CAS:528:DC%2BD1cXot1Ontrc%3D
-
(2008)
J Clin Invest
, vol.118
, pp. 2438-2447
-
-
Kessenbrock, K.1
Fröhlich, L.2
Sixt, M.3
-
53
-
-
34247345082
-
PC cell-derived growth factor stimulates proliferation and confers Trastuzumab resistance to Her-2-overexpressing breast cancer cells
-
16857791 1:CAS:528:DC%2BD28XntFSms7s%3D 10.1158/1078-0432.CCR-05-2663
-
WE Kim G Serrero 2006 PC cell-derived growth factor stimulates proliferation and confers Trastuzumab resistance to Her-2-overexpressing breast cancer cells Clin Cancer Res 12 4192 4199 16857791 1:CAS:528: DC%2BD28XntFSms7s%3D 10.1158/1078-0432.CCR-05-2663
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4192-4199
-
-
Kim, W.E.1
Serrero, G.2
-
54
-
-
68949200351
-
Progranulin expression in advanced human atherosclerotic plaque
-
19321167 1:CAS:528:DC%2BD1MXhtVKlsL%2FK 10.1016/j.atherosclerosis.2009. 02.017
-
Y Kojima K Ono K Inoue, et al. 2009 Progranulin expression in advanced human atherosclerotic plaque Atherosclerosis 206 102 108 19321167 1:CAS:528:DC%2BD1MXhtVKlsL%2FK 10.1016/j.atherosclerosis.2009.02.017
-
(2009)
Atherosclerosis
, vol.206
, pp. 102-108
-
-
Kojima, Y.1
Ono, K.2
Inoue, K.3
-
55
-
-
78149429744
-
Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy
-
20967127 10.1371/journal.pone.0013368 1:CAS:528:DC%2BC3cXhtlels7nJ
-
AS Laird A Van Hoecke L De Muynck, et al. 2010 Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy PLoS ONE 5 e13368 20967127 10.1371/journal.pone.0013368 1:CAS:528: DC%2BC3cXhtlels7nJ
-
(2010)
PLoS ONE
, vol.5
, pp. 13368
-
-
Laird, A.S.1
Van Hoecke, A.2
De Muynck, L.3
-
56
-
-
0037159513
-
IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program
-
12221085 1:CAS:528:DC%2BD38Xosl2lsrk%3D 10.1074/jbc.M205165200
-
X Li PE Massa A Hanidu, et al. 2002 IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program J Biol Chem 277 45129 45140 12221085 1:CAS:528:DC%2BD38Xosl2lsrk%3D 10.1074/jbc.M205165200
-
(2002)
J Biol Chem
, vol.277
, pp. 45129-45140
-
-
Li, X.1
Massa, P.E.2
Hanidu, A.3
-
57
-
-
78650329734
-
Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish
-
20961855 1:CAS:528:DC%2BC3cXhsFynsbzK 10.1074/jbc.M110.138743
-
Y-H Li MH-C Chen H-Y Gong, et al. 2010 Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish J Biol Chem 285 41001 41009 20961855 1:CAS:528:DC%2BC3cXhsFynsbzK 10.1074/jbc.M110.138743
-
(2010)
J Biol Chem
, vol.285
, pp. 41001-41009
-
-
Li, Y.-H.1
Mh-C, C.2
Gong, H.-Y.3
-
58
-
-
0034163549
-
Identification of a human glioma-associated growth factor gene, granulin, using differential immuno-absorption
-
10728698 1:CAS:528:DC%2BD3cXhvFWrt7k%3D
-
LM Liau RL Lallone RS Seitz, et al. 2000 Identification of a human glioma-associated growth factor gene, granulin, using differential immuno-absorption Cancer Res 60 1353 1360 10728698 1:CAS:528: DC%2BD3cXhvFWrt7k%3D
-
(2000)
Cancer Res
, vol.60
, pp. 1353-1360
-
-
Liau, L.M.1
Lallone, R.L.2
Seitz, R.S.3
-
59
-
-
80855153348
-
Progranulin is located in secretory granules and vesicles of neutrophils and macrophages by immunogold electron microscopy: 41.7
-
10.1097/01.jnen.0000268990.82771.11
-
W-L Lin C Zehr J Lewis DW Dickson 2007 Progranulin is located in secretory granules and vesicles of neutrophils and macrophages by immunogold electron microscopy: 41.7 J Neuropathol Exp Neurol 66 422 10.1097/01.jnen. 0000268990.82771.11
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 422
-
-
Lin, W.-L.1
Zehr, C.2
Lewis, J.3
Dickson, D.W.4
-
60
-
-
0034636005
-
Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468
-
10760271 1:CAS:528:DC%2BD3cXislSgt7o%3D 10.1073/pnas.97.8.3993
-
R Lu G Serrero 2000 Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468 Proc Natl Acad Sci 97 3993 3998 10760271 1:CAS:528:DC%2BD3cXislSgt7o%3D 10.1073/pnas.97.8.3993
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 3993-3998
-
-
Lu, R.1
Serrero, G.2
-
61
-
-
0035793102
-
Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor)
-
11134521 1:CAS:528:DC%2BD3MXkslKrtA%3D%3D 10.1073/pnas.011525198
-
R Lu G Serrero 2001 Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor) Proc Natl Acad Sci 98 142 147 11134521 1:CAS:528: DC%2BD3MXkslKrtA%3D%3D 10.1073/pnas.011525198
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 142-147
-
-
Lu, R.1
Serrero, G.2
-
62
-
-
33750590113
-
The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene
-
17071926 10.1093/brain/awl271
-
IRA Mackenzie M Baker S Pickering-Brown, et al. 2006 The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene Brain 129 3081 3090 17071926 10.1093/brain/awl271
-
(2006)
Brain
, vol.129
, pp. 3081-3090
-
-
MacKenzie, I.R.A.1
Baker, M.2
Pickering-Brown, S.3
-
63
-
-
0035085455
-
Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays
-
11279269 1:CAS:528:DC%2BD3MXis1Klt7c%3D 10.1046/j.1471-4159.2001.t01-1- 00231.x
-
A Malaspina N Kaushik J de Belleroche 2001 Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays J Neurochem 77 132 145 11279269 1:CAS:528:DC%2BD3MXis1Klt7c%3D 10.1046/j.1471-4159.2001.t01-1-00231.x
-
(2001)
J Neurochem
, vol.77
, pp. 132-145
-
-
Malaspina, A.1
Kaushik, N.2
De Belleroche, J.3
-
64
-
-
33645047659
-
Oncogenic property of acrogranin in human uterine leiomyosarcoma: Direct evidence of genetic contribution in in vivo tumorigenesis
-
16533762 1:CAS:528:DC%2BD28XitVGmsr8%3D 10.1158/1078-0432.CCR-05-2003
-
N Matsumura M Mandai M Miyanishi, et al. 2006 Oncogenic property of acrogranin in human uterine leiomyosarcoma: direct evidence of genetic contribution in in vivo tumorigenesis Clin Cancer Res 12 1402 1411 16533762 1:CAS:528:DC%2BD28XitVGmsr8%3D 10.1158/1078-0432.CCR-05-2003
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1402-1411
-
-
Matsumura, N.1
Mandai, M.2
Miyanishi, M.3
-
65
-
-
0036500643
-
High-density microarray analysis of hippocampal gene expression following experimental brain injury
-
11891777 1:CAS:528:DC%2BD38XisVKnsbs%3D 10.1002/jnr.10157
-
DA Matzilevich JM Rall AN Moore RJ Grill PK Dash 2002 High-density microarray analysis of hippocampal gene expression following experimental brain injury J Neurosci Res 67 646 663 11891777 1:CAS:528:DC%2BD38XisVKnsbs%3D 10.1002/jnr.10157
-
(2002)
J Neurosci Res
, vol.67
, pp. 646-663
-
-
Matzilevich, D.A.1
Rall, J.M.2
Moore, A.N.3
Grill, R.J.4
Dash, P.K.5
-
66
-
-
33947727094
-
Immortalized ovarian surface epithelial cells acquire tumorigenicity by Acrogranin gene overexpression
-
17203169 1:CAS:528:DC%2BD2sXhvFyltbY%3D
-
M Miyanishi M Mandai N Matsumura, et al. 2007 Immortalized ovarian surface epithelial cells acquire tumorigenicity by Acrogranin gene overexpression Oncol Rep 17 329 333 17203169 1:CAS:528:DC%2BD2sXhvFyltbY%3D
-
(2007)
Oncol Rep
, vol.17
, pp. 329-333
-
-
Miyanishi, M.1
Mandai, M.2
Matsumura, N.3
-
67
-
-
58049221032
-
Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury
-
19046946 1:CAS:528:DC%2BD1MXht1ajtA%3D%3D 10.1016/j.brainres.2008.10.021
-
K Moisse K Volkening C Leystra-Lantz I Welch T Hill MJ Strong 2009 Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury Brain Res 1249 202 211 19046946 1:CAS:528:DC%2BD1MXht1ajtA%3D%3D 10.1016/j.brainres.2008.10.021
-
(2009)
Brain Res
, vol.1249
, pp. 202-211
-
-
Moisse, K.1
Volkening, K.2
Leystra-Lantz, C.3
Welch, I.4
Hill, T.5
Strong, M.J.6
-
68
-
-
33746865874
-
Proepithelin promotes migration and invasion of 5637 bladder cancer cells through the activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex
-
16849556 1:CAS:528:DC%2BD28XmvFGkt7s%3D 10.1158/0008-5472.CAN-06-0633
-
G Monami EM Gonzalez M Hellman, et al. 2006 Proepithelin promotes migration and invasion of 5637 bladder cancer cells through the activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex Cancer Res 66 7103 7110 16849556 1:CAS:528:DC%2BD28XmvFGkt7s%3D 10.1158/0008-5472.CAN-06-0633
-
(2006)
Cancer Res
, vol.66
, pp. 7103-7110
-
-
Monami, G.1
Gonzalez, E.M.2
Hellman, M.3
-
69
-
-
62549091390
-
Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth
-
19179604 1:CAS:528:DC%2BD1MXjs1Wgs7k%3D 10.2353/ajpath.2009.080735
-
G Monami V Emiliozzi A Bitto, et al. 2009 Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth Am J Pathol 174 1037 1047 19179604 1:CAS:528:DC%2BD1MXjs1Wgs7k%3D 10.2353/ajpath.2009.080735
-
(2009)
Am J Pathol
, vol.174
, pp. 1037-1047
-
-
Monami, G.1
Emiliozzi, V.2
Bitto, A.3
-
70
-
-
42049108445
-
Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia
-
18183624 1:CAS:528:DC%2BD1cXlslWlsL4%3D 10.1002/humu.20681
-
O Mukherjee J Wang MA Gitcho, et al. 2008 Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia Hum Mutat 29 512 521 18183624 1:CAS:528:DC%2BD1cXlslWlsL4%3D 10.1002/humu.20681
-
(2008)
Hum Mutat
, vol.29
, pp. 512-521
-
-
Mukherjee, O.1
Wang, J.2
Gitcho, M.A.3
-
71
-
-
77649192710
-
Progranulin expression is upregulated after spinal contusion in mice
-
19946692 1:CAS:528:DC%2BC3cXjtlCgsA%3D%3D 10.1007/s00401-009-0616-y
-
SB Naphade KA Kigerl LB Jakeman SK Kostyk PG Popovich J Kuret 2010 Progranulin expression is upregulated after spinal contusion in mice Acta Neuropathol 119 123 133 19946692 1:CAS:528:DC%2BC3cXjtlCgsA%3D%3D 10.1007/s00401-009-0616-y
-
(2010)
Acta Neuropathol
, vol.119
, pp. 123-133
-
-
Naphade, S.B.1
Kigerl, K.A.2
Jakeman, L.B.3
Kostyk, S.K.4
Popovich, P.G.5
Kuret, J.6
-
72
-
-
26844447994
-
Frontotemporal dementia
-
16239184 10.1016/S1474-4422(05)70223-4
-
D Neary J Snowden D Mann 2005 Frontotemporal dementia Lancet Neurol 4 771 780 16239184 10.1016/S1474-4422(05)70223-4
-
(2005)
Lancet Neurol
, vol.4
, pp. 771-780
-
-
Neary, D.1
Snowden, J.2
Mann, D.3
-
73
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
17023659 1:CAS:528:DC%2BD28XhtVCiurrL 10.1126/science.1134108
-
M Neumann DM Sampathu LK Kwong, et al. 2006 Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 130 133 17023659 1:CAS:528:DC%2BD28XhtVCiurrL 10.1126/science.1134108
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
-
74
-
-
0037452606
-
Activated microglia in cortex of mouse models of mucopolysaccharidoses i and IIIB
-
12576554 1:CAS:528:DC%2BD3sXhsFGrs78%3D 10.1073/pnas.252784899
-
K Ohmi DS Greenberg KS Rajavel S Ryazantsev HH Li EF Neufeld 2003 Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB Proc Natl Acad Sci 100 1902 1907 12576554 1:CAS:528:DC%2BD3sXhsFGrs78%3D 10.1073/pnas.252784899
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 1902-1907
-
-
Ohmi, K.1
Greenberg, D.S.2
Rajavel, K.S.3
Ryazantsev, S.4
Li, H.H.5
Neufeld, E.F.6
-
75
-
-
77954717645
-
HDL/apolipoprotein A-I binds to macrophage-derived progranulin and suppresses its conversion into proinflammatory granulins
-
20215705 1:CAS:528:DC%2BC3MXhvVert7g%3D 10.5551/jat.3921
-
H Okura S Yamashita T Ohama, et al. 2010 HDL/apolipoprotein A-I binds to macrophage-derived progranulin and suppresses its conversion into proinflammatory granulins J Atheroscler Thromb 17 568 577 20215705 1:CAS:528:DC%2BC3MXhvVert7g%3D 10.5551/jat.3921
-
(2010)
J Atheroscler Thromb
, vol.17
, pp. 568-577
-
-
Okura, H.1
Yamashita, S.2
Ohama, T.3
-
76
-
-
77955707871
-
Progranulin expression in the developing and adult murine brain
-
20737593 10.1002/cne.22430
-
TL Petkau SJ Neal PC Orban, et al. 2010 Progranulin expression in the developing and adult murine brain J Comp Neurol 518 3931 3947 20737593 10.1002/cne.22430
-
(2010)
J Comp Neurol
, vol.518
, pp. 3931-3947
-
-
Petkau, T.L.1
Neal, S.J.2
Orban, P.C.3
-
77
-
-
79951704433
-
Neuroinflammation in amyotrophic lateral sclerosis: Role of glial activation in motor neuron disease
-
21349440 1:CAS:528:DC%2BC3MXit1Wktr8%3D 10.1016/S1474-4422(11)70015-1
-
T Philips W Robberecht 2011 Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease Lancet Neurol 10 253 263 21349440 1:CAS:528:DC%2BC3MXit1Wktr8%3D 10.1016/S1474-4422(11)70015-1
-
(2011)
Lancet Neurol
, vol.10
, pp. 253-263
-
-
Philips, T.1
Robberecht, W.2
-
78
-
-
78650178041
-
Microglial upregulation of progranulin as a marker of motor neuron degeneration
-
21107132 1:CAS:528:DC%2BC3cXhsV2nsr7J 10.1097/NEN.0b013e3181fc9aea
-
T Philips L De Muynck HNT Thu, et al. 2010 Microglial upregulation of progranulin as a marker of motor neuron degeneration J Neuropathol Exp Neurol 69 1191 1200 21107132 1:CAS:528:DC%2BC3cXhsV2nsr7J 10.1097/NEN.0b013e3181fc9aea
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, pp. 1191-1200
-
-
Philips, T.1
De Muynck, L.2
Thu, H.N.T.3
-
79
-
-
79251482777
-
Progranulin is a chemoattractant for microglia and stimulates their endocytic activity
-
21224065 1:CAS:528:DC%2BC3MXitFGjsL0%3D 10.1016/j.ajpath.2010.11.002
-
F Pickford J Marcus LM Camargo, et al. 2011 Progranulin is a chemoattractant for microglia and stimulates their endocytic activity Am J Pathol 178 284 295 21224065 1:CAS:528:DC%2BC3MXitFGjsL0%3D 10.1016/j.ajpath. 2010.11.002
-
(2011)
Am J Pathol
, vol.178
, pp. 284-295
-
-
Pickford, F.1
Marcus, J.2
Camargo, L.M.3
-
80
-
-
34247359882
-
Prosurvival function of the granulin-epithelin precursor is important in tumor progression and chemoresponse
-
17266030 1:CAS:528:DC%2BD2sXksFSktb4%3D 10.1002/ijc.22559
-
GO Pizarro XC Zhou A Koch, et al. 2007 Prosurvival function of the granulin-epithelin precursor is important in tumor progression and chemoresponse Int J Cancer 120 2339 2343 17266030 1:CAS:528:DC%2BD2sXksFSktb4%3D 10.1002/ijc.22559
-
(2007)
Int J Cancer
, vol.120
, pp. 2339-2343
-
-
Pizarro, G.O.1
Zhou, X.C.2
Koch, A.3
-
81
-
-
0026717054
-
The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth
-
1618805 1:CAS:528:DyaK3sXisVygtbY%3D
-
GD Plowman JM Green MG Neubauer, et al. 1992 The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth J Biol Chem 267 13073 13078 1618805 1:CAS:528:DyaK3sXisVygtbY%3D
-
(1992)
J Biol Chem
, vol.267
, pp. 13073-13078
-
-
Plowman, G.D.1
Green, J.M.2
Neubauer, M.G.3
-
82
-
-
23844556836
-
Effects of progranulin on blastocyst hatching and subsequent adhesion and outgrowth in the mouse
-
15901638 1:CAS:528:DC%2BD2MXovV2qt70%3D 10.1095/biolreprod.105.040030
-
J Qin L Díaz-Cueto J Schwarze, et al. 2005 Effects of progranulin on blastocyst hatching and subsequent adhesion and outgrowth in the mouse Biol Reprod 73 434 442 15901638 1:CAS:528:DC%2BD2MXovV2qt70%3D 10.1095/biolreprod. 105.040030
-
(2005)
Biol Reprod
, vol.73
, pp. 434-442
-
-
Qin, J.1
Díaz-Cueto, L.2
Schwarze, J.3
-
83
-
-
0037062609
-
The prevalence of frontotemporal dementia
-
12058088 1:STN:280:DC%2BD38zhsFWguw%3D%3D
-
E Ratnavalli C Brayne K Dawson JR Hodges 2002 The prevalence of frontotemporal dementia Neurology 58 1615 1621 12058088 1:STN:280: DC%2BD38zhsFWguw%3D%3D
-
(2002)
Neurology
, vol.58
, pp. 1615-1621
-
-
Ratnavalli, E.1
Brayne, C.2
Dawson, K.3
Hodges, J.R.4
-
84
-
-
70749120467
-
Progranulin is expressed within motor neurons and promotes neuronal cell survival
-
19860916 10.1186/1471-2202-10-130 1:CAS:528:DC%2BD1MXhtlOhurvL
-
CL Ryan DC Baranowski BP Chitramuthu, et al. 2009 Progranulin is expressed within motor neurons and promotes neuronal cell survival BMC Neurosci 10 130 19860916 10.1186/1471-2202-10-130 1:CAS:528:DC%2BD1MXhtlOhurvL
-
(2009)
BMC Neurosci
, vol.10
, pp. 130
-
-
Ryan, C.L.1
Baranowski, D.C.2
Chitramuthu, B.P.3
-
85
-
-
38349173569
-
Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion
-
17984093 1:CAS:528:DC%2BD1cXks1CitQ%3D%3D 10.1074/jbc.M705115200
-
SS Shankaran A Capell AT Hruscha, et al. 2008 Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion J Biol Chem 283 1744 1753 17984093 1:CAS:528:DC%2BD1cXks1CitQ%3D%3D 10.1074/jbc.M705115200
-
(2008)
J Biol Chem
, vol.283
, pp. 1744-1753
-
-
Shankaran, S.S.1
Capell, A.2
Hruscha, A.T.3
-
86
-
-
0025133297
-
Epithelins 1 and 2: Isolation and characterization of two cysteine-rich growth-modulating proteins
-
2236009 1:CAS:528:DyaK3MXnsFejtg%3D%3D 10.1073/pnas.87.20.7912
-
M Shoyab VL McDonald C Byles GJ Todaro GD Plowman 1990 Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins Proc Natl Acad Sci 87 7912 7916 2236009 1:CAS:528:DyaK3MXnsFejtg%3D%3D 10.1073/pnas.87.20.7912
-
(1990)
Proc Natl Acad Sci
, vol.87
, pp. 7912-7916
-
-
Shoyab, M.1
McDonald, V.L.2
Byles, C.3
Todaro, G.J.4
Plowman, G.D.5
-
87
-
-
67249111266
-
Serum biomarker for progranulin-associated frontotemporal lobar degeneration
-
19288468 1:CAS:528:DC%2BD1MXnvFahsb4%3D 10.1002/ana.21621
-
K Sleegers N Brouwers P Van Damme, et al. 2009 Serum biomarker for progranulin-associated frontotemporal lobar degeneration Ann Neurol 65 603 609 19288468 1:CAS:528:DC%2BD1MXnvFahsb4%3D 10.1002/ana.21621
-
(2009)
Ann Neurol
, vol.65
, pp. 603-609
-
-
Sleegers, K.1
Brouwers, N.2
Van Damme, P.3
-
88
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
15784165 1:CAS:528:DC%2BD2MXlt1eqtLo%3D 10.1111/j.1582-4934.2005.tb00337. x
-
G Song G Ouyang S Bao 2005 The activation of Akt/PKB signaling pathway and cell survival J Cell Mol Med 9 59 71 15784165 1:CAS:528:DC%2BD2MXlt1eqtLo%3D 10.1111/j.1582-4934.2005.tb00337.x
-
(2005)
J Cell Mol Med
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
89
-
-
79957538748
-
Expression pattern of progranulin in the human placenta and its effect on cell proliferation in the choriocarcinoma cell line BeWo
-
Stubert J, Richter D-U, Gerber B, Briese V (2010) Expression pattern of progranulin in the human placenta and its effect on cell proliferation in the choriocarcinoma cell line BeWo. J Reprod Dev 57:229-235
-
(2010)
J Reprod Dev
, vol.57
, pp. 229-235
-
-
Stubert, J.1
Richter, D.-U.2
Gerber, B.3
Briese, V.4
-
90
-
-
0034667758
-
Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase
-
11068878 1:CAS:528:DC%2BD3cXntVWguro%3D 10.1006/abbi.2000.2019
-
D Sui JE Wilson 2000 Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase Arch Biochem Biophys 382 262 274 11068878 1:CAS:528:DC%2BD3cXntVWguro%3D 10.1006/abbi.2000.2019
-
(2000)
Arch Biochem Biophys
, vol.382
, pp. 262-274
-
-
Sui, D.1
Wilson, J.E.2
-
91
-
-
79955477738
-
The growth factor progranulin binds to tnf receptors and is therapeutic against inflammatory arthritis in mice
-
21393509 1:CAS:528:DC%2BC3MXkvValsrY%3D 10.1126/science.1199214
-
W Tang Y Lu Q-Y Tian, et al. 2011 The growth factor progranulin binds to tnf receptors and is therapeutic against inflammatory arthritis in mice Science 332 478 484 21393509 1:CAS:528:DC%2BC3MXkvValsrY%3D 10.1126/science.1199214
-
(2011)
Science
, vol.332
, pp. 478-484
-
-
Tang, W.1
Lu, Y.2
Tian, Q.-Y.3
-
92
-
-
4544367851
-
PC cell-derived growth factor (PCDGF/GP88, progranulin) stimulates migration, invasiveness and VEGF expression in breast cancer cells
-
15117809 1:CAS:528:DC%2BD2cXntFahsr8%3D 10.1093/carcin/bgh171
-
W Tangkeangsirisin G Serrero 2004 PC cell-derived growth factor (PCDGF/GP88, progranulin) stimulates migration, invasiveness and VEGF expression in breast cancer cells Carcinogenesis 25 1587 1592 15117809 1:CAS:528:DC%2BD2cXntFahsr8%3D 10.1093/carcin/bgh171
-
(2004)
Carcinogenesis
, vol.25
, pp. 1587-1592
-
-
Tangkeangsirisin, W.1
Serrero, G.2
-
93
-
-
1642266452
-
PC cell-derived growth factor mediates tamoxifen resistance and promotes tumor growth of human breast cancer cells
-
14996734 1:CAS:528:DC%2BD2cXhsleku74%3D 10.1158/0008-5472.CAN-03-2364
-
W Tangkeangsirisin J Hayashi G Serrero 2004 PC cell-derived growth factor mediates tamoxifen resistance and promotes tumor growth of human breast cancer cells Cancer Res 64 1737 1743 14996734 1:CAS:528:DC%2BD2cXhsleku74%3D 10.1158/0008-5472.CAN-03-2364
-
(2004)
Cancer Res
, vol.64
, pp. 1737-1743
-
-
Tangkeangsirisin, W.1
Hayashi, J.2
Serrero, G.3
-
94
-
-
0033574221
-
Epithelin/granulin growth factors: Extracellular cofactors for HIV-1 and HIV-2 Tat proteins
-
10079180 1:CAS:528:DyaK1MXhvVaiurg%3D 10.1006/bbrc.1999.0317
-
DP Trinh KM Brown KT Jeang 1999 Epithelin/granulin growth factors: extracellular cofactors for HIV-1 and HIV-2 Tat proteins Biochem Biophys Res Commun 256 299 306 10079180 1:CAS:528:DyaK1MXhvVaiurg%3D 10.1006/bbrc.1999.0317
-
(1999)
Biochem Biophys Res Commun
, vol.256
, pp. 299-306
-
-
Trinh, D.P.1
Brown, K.M.2
Jeang, K.T.3
-
95
-
-
0029102880
-
Somatostatin-, vasoactive intestinal eptide-, and granulin-like peptides isolated from intestinal extracts of goldfish, Carassius auratus
-
8536941 1:CAS:528:DyaK2MXnvVeks7k%3D 10.1006/gcen.1995.1113
-
T Uesaka K Yano M Yamasaki M Ando 1995 Somatostatin-, vasoactive intestinal eptide-, and granulin-like peptides isolated from intestinal extracts of goldfish, Carassius auratus Gen Comp Endocrinol 99 298 306 8536941 1:CAS:528:DyaK2MXnvVeks7k%3D 10.1006/gcen.1995.1113
-
(1995)
Gen Comp Endocrinol
, vol.99
, pp. 298-306
-
-
Uesaka, T.1
Yano, K.2
Yamasaki, M.3
Ando, M.4
-
96
-
-
42049087853
-
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
-
18378771 10.1083/jcb.200712039 1:CAS:528:DC%2BD1cXks1Gktbk%3D
-
P Van Damme A Van Hoecke D Lambrechts, et al. 2008 Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival J Cell Biol 181 37 41 18378771 10.1083/jcb.200712039 1:CAS:528:DC%2BD1cXks1Gktbk%3D
-
(2008)
J Cell Biol
, vol.181
, pp. 37-41
-
-
Van Damme, P.1
Van Hoecke, A.2
Lambrechts, D.3
-
97
-
-
34247868937
-
Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia
-
17345602
-
J van der Zee I Le Ber S Maurer-Stroh, et al. 2007 Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia Hum Mutat 28 416 17345602
-
(2007)
Hum Mutat
, vol.28
, pp. 416
-
-
Van Der Zee, J.1
Le Ber, I.2
Maurer-Stroh, S.3
-
98
-
-
0038514929
-
PC cell-derived growth factor (granulin precursor) expression and action in human multiple myeloma
-
12796389 1:CAS:528:DC%2BD3sXksVWqu7c%3D
-
W Wang J Hayashi WE Kim G Serrero 2003 PC cell-derived growth factor (granulin precursor) expression and action in human multiple myeloma Clin Cancer Res 9 2221 2228 12796389 1:CAS:528:DC%2BD3sXksVWqu7c%3D
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2221-2228
-
-
Wang, W.1
Hayashi, J.2
Kim, W.E.3
Serrero, G.4
-
99
-
-
31544434306
-
PC cell-derived growth factor confers resistance to dexamethasone and promotes tumorigenesis in human multiple myeloma
-
16397023 1:CAS:528:DC%2BD28Xht1Grug%3D%3D 10.1158/1078-0432.CCR-05-0929
-
W Wang J Hayashi G Serrero 2006 PC cell-derived growth factor confers resistance to dexamethasone and promotes tumorigenesis in human multiple myeloma Clin Cancer Res 12 49 56 16397023 1:CAS:528:DC%2BD28Xht1Grug%3D%3D 10.1158/1078-0432.CCR-05-0929
-
(2006)
Clin Cancer Res
, vol.12
, pp. 49-56
-
-
Wang, W.1
Hayashi, J.2
Serrero, G.3
-
100
-
-
75949130374
-
Pathogenic cysteine mutations affect progranulin function and production of mature granulins
-
20028451 1:CAS:528:DC%2BC3cXisVCis70%3D 10.1111/j.1471-4159.2009.06546.x
-
J Wang P Van Damme C Cruchaga, et al. 2010 Pathogenic cysteine mutations affect progranulin function and production of mature granulins J Neurochem 112 1305 1315 20028451 1:CAS:528:DC%2BC3cXisVCis70%3D 10.1111/j.1471-4159.2009. 06546.x
-
(2010)
J Neurochem
, vol.112
, pp. 1305-1315
-
-
Wang, J.1
Van Damme, P.2
Cruchaga, C.3
-
101
-
-
0032540126
-
Identification of cell surface binding sites for PC-cell-derived growth factor, PCDGF, (epithelin/granulin precursor) on epithelial cells and fibroblasts
-
9571191 1:CAS:528:DyaK1cXivVyjsLo%3D 10.1006/bbrc.1998.8498
-
X Xia G Serrero 1998 Identification of cell surface binding sites for PC-cell-derived growth factor, PCDGF, (epithelin/granulin precursor) on epithelial cells and fibroblasts Biochem Biophys Res Commun 245 539 543 9571191 1:CAS:528:DyaK1cXivVyjsLo%3D 10.1006/bbrc.1998.8498
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 539-543
-
-
Xia, X.1
Serrero, G.2
-
102
-
-
0032493827
-
The granulin/epithelin precursor abrogates the requirement for the insulin-like growth factor 1 receptor for growth in vitro
-
9685348 1:CAS:528:DyaK1cXlsVWgsLY%3D 10.1074/jbc.273.32.20078
-
SQ Xu D Tang S Chamberlain, et al. 1998 The granulin/epithelin precursor abrogates the requirement for the insulin-like growth factor 1 receptor for growth in vitro J Biol Chem 273 20078 20083 9685348 1:CAS:528:DyaK1cXlsVWgsLY%3D 10.1074/jbc.273.32.20078
-
(1998)
J Biol Chem
, vol.273
, pp. 20078-20083
-
-
Xu, S.Q.1
Tang, D.2
Chamberlain, S.3
-
103
-
-
34249683186
-
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation
-
17307734 1:CAS:528:DC%2BD2sXjvFagt7g%3D 10.1074/jbc.M608744200
-
K Xu Y Zhang K Ilalov, et al. 2007 Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation J Biol Chem 282 11347 11355 17307734 1:CAS:528:DC%2BD2sXjvFagt7g%3D 10.1074/jbc.M608744200
-
(2007)
J Biol Chem
, vol.282
, pp. 11347-11355
-
-
Xu, K.1
Zhang, Y.2
Ilalov, K.3
-
104
-
-
57049104077
-
Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach
-
18596065 1:CAS:528:DC%2BD1cXhsVaqsL%2FE 10.1074/mcp.M800095-MCP200
-
D Xu N Suenaga MJ Edelmann R Fridman RJ Muschel BM Kessler 2008 Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach Mol Cell Proteomics 7 2215 2228 18596065 1:CAS:528:DC%2BD1cXhsVaqsL%2FE 10.1074/mcp.M800095-MCP200
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 2215-2228
-
-
Xu, D.1
Suenaga, N.2
Edelmann, M.J.3
Fridman, R.4
Muschel, R.J.5
Kessler, B.M.6
-
105
-
-
76149118401
-
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
-
20026663 1:CAS:528:DC%2BC3cXht1ektrY%3D 10.1084/jem.20091568
-
F Yin R Banerjee B Thomas, et al. 2010 Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice J Exp Med 207 117 128 20026663 1:CAS:528:DC%2BC3cXht1ektrY%3D 10.1084/jem.20091568
-
(2010)
J Exp Med
, vol.207
, pp. 117-128
-
-
Yin, F.1
Banerjee, R.2
Thomas, B.3
-
106
-
-
78149296002
-
Behavioral deficits and progressive neuropathology in progranulin-deficient mice: A mouse model of frontotemporal dementia
-
20667979 1:CAS:528:DC%2BC3cXhsFOms7zM 10.1096/fj.10-161471
-
F Yin M Dumont R Banerjee, et al. 2010 Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia FASEB J 24 4639 4647 20667979 1:CAS:528: DC%2BC3cXhsFOms7zM 10.1096/fj.10-161471
-
(2010)
FASEB J
, vol.24
, pp. 4639-4647
-
-
Yin, F.1
Dumont, M.2
Banerjee, R.3
-
107
-
-
62749143509
-
Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue
-
19056610 1:CAS:528:DC%2BD1MXjt1Wktr4%3D 10.2337/db08-1147
-
B-S Youn S-I Bang N Kloeting, et al. 2009 Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue Diabetes 58 627 636 19056610 1:CAS:528:DC%2BD1MXjt1Wktr4%3D 10.2337/db08-1147
-
(2009)
Diabetes
, vol.58
, pp. 627-636
-
-
Youn, B.-S.1
Bang, S.-I.2
Kloeting, N.3
-
108
-
-
0032749572
-
Biological activities and signaling pathways of the granulin/epithelin precursor
-
10537317 1:CAS:528:DyaK1MXmvFeltrw%3D
-
T Zanocco-Marani A Bateman G Romano B Valentinis ZH He R Baserga 1999 Biological activities and signaling pathways of the granulin/epithelin precursor Cancer Res 59 5331 5340 10537317 1:CAS:528:DyaK1MXmvFeltrw%3D
-
(1999)
Cancer Res
, vol.59
, pp. 5331-5340
-
-
Zanocco-Marani, T.1
Bateman, A.2
Romano, G.3
Valentinis, B.4
He, Z.H.5
Baserga, R.6
-
109
-
-
0032564360
-
Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor)
-
9826678 1:CAS:528:DyaK1cXns1GmurY%3D 10.1073/pnas.95.24.14202
-
H Zhang G Serrero 1998 Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) Proc Natl Acad Sci 95 14202 14207 9826678 1:CAS:528:DyaK1cXns1GmurY%3D 10.1073/pnas.95.24.14202
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 14202-14207
-
-
Zhang, H.1
Serrero, G.2
-
110
-
-
34848921202
-
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
-
17898224 1:CAS:528:DC%2BD2sXhtFGmt7fO 10.1523/JNEUROSCI.3421-07.2007
-
Y-J Zhang Y-F Xu CA Dickey, et al. 2007 Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43 J Neurosci 27 10530 10534 17898224 1:CAS:528:DC%2BD2sXhtFGmt7fO 10.1523/JNEUROSCI.3421-07.2007
-
(2007)
J Neurosci
, vol.27
, pp. 10530-10534
-
-
Zhang, Y.-J.1
Xu, Y.-F.2
Dickey, C.A.3
-
111
-
-
0027241980
-
Purification of an autocrine growth factor homologous with mouse epithelin precursor from a highly tumorigenic cell line
-
8496151 1:CAS:528:DyaK3sXksVWrsLo%3D
-
J Zhou G Gao JW Crabb G Serrero 1993 Purification of an autocrine growth factor homologous with mouse epithelin precursor from a highly tumorigenic cell line J Biol Chem 268 10863 10869 8496151 1:CAS:528:DyaK3sXksVWrsLo%3D
-
(1993)
J Biol Chem
, vol.268
, pp. 10863-10869
-
-
Zhou, J.1
Gao, G.2
Crabb, J.W.3
Serrero, G.4
-
112
-
-
0037074016
-
Conversion of proepithelin to epithelins: Roles of SLPI and elastase in host defense and wound repair
-
12526812 1:CAS:528:DC%2BD3sXhtVyksw%3D%3D 10.1016/S0092-8674(02)01141-8
-
J Zhu C Nathan W Jin, et al. 2002 Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair Cell 111 867 878 12526812 1:CAS:528:DC%2BD3sXhtVyksw%3D%3D 10.1016/S0092-8674(02)01141-8
-
(2002)
Cell
, vol.111
, pp. 867-878
-
-
Zhu, J.1
Nathan, C.2
Jin, W.3
|