Modeling Focal Cerebral Ischemia In Vivo

Methods in Molecular Biology

Volumn 793, Issue , 2011, Pages 195-209

  Jackman, Katherine ^a   Kunz, Alexander ^a   Iadecola, Costantino ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Brain ischemia; Focal ischemia; Laser Doppler flowmetry; Mice; Middle cerebral artery occlusion; Reperfusion; String model; Transient ischemia

Indexed keywords

ANIMALIA; MUS;

NYLON;

ANIMAL; ARTICLE; C57BL MOUSE; CATHETERIZATION; CEREBRAL ARTERY DISEASE; DISEASE MODEL; FEMORAL ARTERY; HEAT; MALE; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; SUTURE;

ANIMALS; CATHETERIZATION; DISEASE MODELS, ANIMAL; FEMORAL ARTERY; HOT TEMPERATURE; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; NYLONS; SUTURES;

EID: 80054773930     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-328-8_13     Document Type: Chapter

References (32)

1. De Freitas, G. R., Christoph Dde, H., and Bogousslavsky, J. (2008) Chapter 22 Topographic classification of ischemic stroke. Handb Clin Neurol. 93, 425–452.
2. Koizumi, J., Yoshida, Y., Nakazawa, T., and Oneda, G. (1986) A new experimental model of cerebral embolism in rats in which recircula-tion can be introduced in the ischemia area. Jpn J of Stroke. 8, 1–8.
3. Longa, E. Z., Weinstein, P. R., Carlson, S., and Cummins, R. (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 20, 84–91.
4. Belayev, L., Alonso, O. F., Busto, R., Zhao, W., and Ginsberg, M. D. (1996) Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke. 27, 1616– 1622; discussion 1623.
5. Clark, W. M., Lessov, N. S., Dixon, M. P., and Eckenstein, F. (1997) Monofilament intraluminal middle cerebral artery occlusion in the mouse. Neurol Res. 19, 641–648.
6. Schmid-Elsaesser, R., Zausinger, S., Hungerhuber, E., Baethmann, A., and Reulen, H. J. (1998) A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flowmetry. Stroke. 29, 2162–2170.
7. Tsuchiya, D., Hong, S., Kayama, T., Panter, S. S., and Weinstein, P. R. (2003) Effect of suture size and carotid clip application upon blood flow and infarct volume after permanent and temporary middle cerebral artery occlusion in mice. Brain Res. 970, 131–139.
8. Hata, R., Mies, G., Wiessner, C., Fritze, K., Hesselbarth, D., Brinker, G., and Hossmann, K. A. (1998) A reproducible model of middle cerebral artery occlusion in mice: hemodynamic, biochemical, and magnetic resonance imaging. J Cereb Blood Flow Metab. 18, 367–375.
9. Tureyen, K., Vemuganti, R., Sailor, K. A., and Dempsey, R. J. (2005) Ideal suture diameter is critical for consistent middle cerebral artery occlusion in mice. Neurosurgery. 56, 196–200; discussion 196–200.
10. Bederson, J. B., Pitts, L. H., Tsuji, M., Nishimura, M. C., Davis, R. L., and Bartkowski, H. (1986) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke. 17, 472–476.
11. Freitag, S., Schachner, M., and Morellini, F. (2003) Behavioral alterations in mice deficient for the extracellular matrix glycoprotein tenas-cin-R. Behav Brain Res. 145, 189–207.
12. Ikegami, S., Harada, A., and Hirokawa, N. (2000) Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice. Neurosci Lett. 279, 129–132.
13. Li, X., Blizzard, K. K., Zeng, Z., DeVries, A. C., Hurn, P. D., and McCullough, L. D. (2004) Chronic behavioral testing after focal ischemia in the mouse: functional recovery and the effects of gender. Exp Neurol. 187, 94–104.
14. Zhang, L., Schallert, T., Zhang, Z. G., Jiang, Q., Arniego, P., Li, Q., Lu, M., and Chopp, M. (2002) A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia. J Neurosci Methods. 117, 207–214.
15. Lin, T. N., He, Y. Y., Wu, G., Khan, M., and Hsu, C. Y. (1993) Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke. 24, 117–121.
16. Swanson, R. A., Morton, M. T., Tsao-Wu, G., Savalos, R. A., Davidson, C., and Sharp, F. R. (1990) A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab. 10, 290–293.
17. Laing, R. J., Jakubowski, J., and Laing, R. W. (1993) Middle cerebral artery occlusion without craniectomy in rats. Which method works best? Stroke. 24, 294–297; discussion 297–298.
18. Cho, S., Park, E. M., Febbraio, M., Anrather, J., Park, L., Racchumi, G., Silverstein, R. L., and Iadecola, C. (2005) The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia. J Neurosci. 25, 2504–2512.
19. Cho, S., Park, E. M., Zhou, P., Frys, K., Ross, M. E., and Iadecola, C. (2005) Obligatory role of inducible nitric oxide synthase in ischemic preconditioning. J Cereb Blood Flow Metab. 25, 493–501.
20. Kunz, A., Abe, T., Hochrainer, K., Shimamura, M., Anrather, J., Racchumi, G., Zhou, P., and Iadecola, C. (2008) Nuclear factor-kappaB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion. J Neurosci. 28, 1649–1658.
21. Kunz, A., Anrather, J., Zhou, P., Orio, M., and Iadecola, C. (2007) Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species. J Cereb Blood Flow Metab. 27, 545–551.
22. Kunz, A., Park, L., Abe, T., Gallo, E. F., Anrather, J., Zhou, P., and Iadecola, C. (2007) Neurovascular protection by ischemic tolerance: role of nitric oxide and reactive oxygen species. J Neurosci. 27, 7083–7093.
23. Park, E. M., Cho, S., Frys, K., Racchumi, G., Zhou, P., Anrather, J., and Iadecola, C. (2004) Interaction between inducible nitric oxide synthase and poly(ADP-ribose) polymerase in focal ischemic brain injury. Stroke. 35, 2896–2901.
24. Park, E. M., Cho, S., Frys, K. A., Glickstein, S. B., Zhou, P., Anrather, J., Ross, M. E., and Iadecola, C. (2006) Inducible nitric oxide synthase contributes to gender differences in ischemic brain injury. J Cereb Blood Flow Metab. 26, 392–401.
25. Abe, T., Shimamura, M., Jackman, K., Kurinami, H., Anrather, J., Zhou, P., and Iadecola, C. Key role of CD36 in Toll-like receptor 2 signaling in cerebral ischemia. Stroke. 41, 898–904.
26. Crack, P. J., Taylor, J. M., Flentjar, N. J., de Haan, J., Hertzog, P., Iannello, R. C., and Kola, I. (2001) Increased infarct size and exacerbated apoptosis in the glutathione peroxi-dase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury. J Neurochem. 78, 1389–1399.
27. Ducruet, A. F., Hassid, B. G., Mack, W. J., Sosunov, S. A., Otten, M. L., Fusco, D. J., Hickman, Z. L., Kim, G. H., Komotar, R. J., Mocco, J., and Connolly, E. S. (2008) C3a receptor modulation of granulocyte infiltration after murine focal cerebral ischemia is reperfusion dependent. J Cereb Blood Flow Metab. 28, 1048–1058.
28. Krieger, D. W., and Yenari, M. A. (2004) Therapeutic hypothermia for acute ischemic stroke: what do laboratory studies teach us? Stroke. 35, 1482–1489.
29. McIlvoy, L. H. (2005) The effect of hypothermia and hyperthermia on acute brain injury. AACN Clin Issues. 16, 488–500.
30. Hasegawa, Y., Latour, L. L., Sotak, C. H., Dardzinski, B. J., and Fisher, M. (1994) Temperature dependent change of apparent diffusion coefficient of water in normal and ischemic brain of rats. J Cereb Blood Flow Metab. 14, 383–390.
31. Ergul, A., Li, W., Elgebaly, M. M., Bruno, A., and Fagan, S. C. (2009) Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature. Vascul Pharmacol. 51, 44–49.
32. Tureyen, K., Vemuganti, R., Sailor, K. A., and Dempsey, R. J. (2004) Infarct volume quantification in mouse focal cerebral ischemia: a comparison of triphenyltetrazolium chloride and cresyl violet staining techniques. J Neurosci Methods. 139, 203–207.