Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia

Hypertension

Volumn 60, Issue 1, 2012, Pages 106-113

  Capone, Carmen ^a   Faraco, Giuseppe ^a   Coleman, Christal ^a   Young, Colin N ^c   Pickel, Virginia M ^a   Anrather, Josef ^a   Davisson, Robin L ^b,c   Iadecola, Costantino ^a  

^a Division of Neurobiology   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c Department of Molecular Biology and Genetics   (United States)

Author keywords

Endothelium dependent vasodilation; Neurovascular coupling; Obstructive sleep apnea; Reactive oxygen species

Indexed keywords

ENDOTHELIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ACETYLCHOLINE; ANTIHYPERTENSIVE AGENT; ASPARTIC PROTEINASE; CYBB PROTEIN, MOUSE; CYCLO(TRP ASP PRO VAL LEU); CYCLO(TRP-ASP-PRO-VAL-LEU); CYCLOPEPTIDE; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN RECEPTOR; ENDOTHELIN-CONVERTING ENZYME; MEMBRANE PROTEIN; METALLOPROTEINASE; REACTIVE OXYGEN METABOLITE; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; CEREBROVASCULAR DISEASE; CHRONIC INTERMITTENT HYPOXIA; CONTROLLED STUDY; LASER DOPPLER FLOWMETRY; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SOMATOSENSORY CORTEX; ANIMAL; ANOXIA; BLOOD; BLOOD PRESSURE; BRAIN CIRCULATION; C57BL MOUSE; CHRONIC DISEASE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULARIZATION;

ACETYLCHOLINE; ANIMALS; ANOXIA; ANTIHYPERTENSIVE AGENTS; ASPARTIC ACID ENDOPEPTIDASES; BLOOD PRESSURE; CEREBROVASCULAR CIRCULATION; CHRONIC DISEASE; ENDOTHELIN-1; ENZYME-LINKED IMMUNOSORBENT ASSAY; LASER-DOPPLER FLOWMETRY; MALE; MEMBRANE GLYCOPROTEINS; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADPH OXIDASE; PEPTIDES, CYCLIC; REACTIVE OXYGEN SPECIES; RECEPTORS, ENDOTHELIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SOMATOSENSORY CORTEX; VASODILATOR AGENTS;

EID: 84865825915     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.193672     Document Type: Article

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