Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice

Annals of Internal Medicine

Volumn 158, Issue 6, 2013, Pages 5352-5362

  Roberson, Erik D ^a   Filiano, Anthony J ^a   Martens, Lauren Herl ^b   Young, Allen H ^a   Warmus, Brian A ^b   Zhou, Ping ^b   Diaz Ramirez, Grisell ^b   Jiao, Jian ^e   Zhang, Zhijun ^e   Huang, Eric J ^d   Gao, Fen Biao ^e   Farese, Robert V ^b,c  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PHEROMONE; PROGRANULIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR DISORDER; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; EMOTIONAL DISORDER; ENZYME LINKED IMMUNOSORBENT ASSAY; FEAR; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE; GENE MUTATION; GENE SILENCING; GLIOSIS; GOLGI STAIN; IMMUNOHISTOCHEMISTRY; LIPOFUSCINOSIS; MALE; MEMORY; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NEUROPHYSIOLOGY; NONHUMAN; OPEN FIELD BEHAVIOR; PHENOTYPE; PRIORITY JOURNAL; PROGRANULIN GENE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOCIAL DISABILITY; SPATIAL LEARNING; VISUAL ORIENTATION;

AMYGDALA; ANIMALS; BEHAVIOR, ANIMAL; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; EMOTIONS; ENCEPHALITIS; FEMALE; FRONTOTEMPORAL DEMENTIA; GLIOSIS; HAPLOINSUFFICIENCY; HOMOZYGOTE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MAZE LEARNING; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; PHENOTYPE; SOCIAL BEHAVIOR; SPATIAL BEHAVIOR;

EID: 84877099960     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6103-11.2013     Document Type: Article

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