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Volumn 110, Issue 49, 2013, Pages

Rho GTPases orient directional sensing in chemotaxis

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; RAS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84889644576     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1312540110     Document Type: Article
Times cited : (37)

References (58)
  • 2
    • 77957259884 scopus 로고    scopus 로고
    • The signaling mechanisms underlying cell polarity and chemotaxis
    • Wang F (2009) The signaling mechanisms underlying cell polarity and chemotaxis. Cold Spring Harb Perspect Biol 1(4):a002980.
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , Issue.4
    • Wang, F.1
  • 3
    • 77951249100 scopus 로고    scopus 로고
    • Cell migration during morphogenesis
    • Aman A, Piotrowski T (2010) Cell migration during morphogenesis. Dev Biol 341(1): 20-33.
    • (2010) Dev Biol , vol.341 , Issue.1 , pp. 20-33
    • Aman, A.1    Piotrowski, T.2
  • 4
    • 73649114969 scopus 로고    scopus 로고
    • Molecular layers underlying cytoskeletal remodeling during cortical development
    • Heng JI, Chariot A, Nguyen L (2010) Molecular layers underlying cytoskeletal remodeling during cortical development. Trends Neurosci 33(1):38-47.
    • (2010) Trends Neurosci , vol.33 , Issue.1 , pp. 38-47
    • Heng, J.I.1    Chariot, A.2    Nguyen, L.3
  • 5
    • 70249116807 scopus 로고    scopus 로고
    • Actin dynamics at the leading edge: From simple machinery to complex networks
    • Insall RH, Machesky LM (2009) Actin dynamics at the leading edge: From simple machinery to complex networks. Dev Cell 17(3):310-322.
    • (2009) Dev Cell , vol.17 , Issue.3 , pp. 310-322
    • Insall, R.H.1    Machesky, L.M.2
  • 6
    • 68049083547 scopus 로고    scopus 로고
    • Random versus directionally persistent cell migration
    • Petrie RJ, Doyle AD, Yamada KM (2009) Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol 10(8):538-549.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.8 , pp. 538-549
    • Petrie, R.J.1    Doyle, A.D.2    Yamada, K.M.3
  • 7
    • 77952911072 scopus 로고    scopus 로고
    • Eukaryotic chemotaxis: A network of signaling pathways controls motility, directional sensing, and polarity
    • Swaney KF, Huang CH, Devreotes PN (2010) Eukaryotic chemotaxis: A network of signaling pathways controls motility, directional sensing, and polarity. Annu Rev Biophys 39:265-289.
    • (2010) Annu Rev Biophys , vol.39 , pp. 265-289
    • Swaney, K.F.1    Huang, C.H.2    Devreotes, P.N.3
  • 8
    • 79956143423 scopus 로고    scopus 로고
    • Signaling mechanisms for chemotaxis
    • Wang Y, Chen CL, Iijima M (2011) Signaling mechanisms for chemotaxis. Dev Growth Differ 53(4):495-502.
    • (2011) Dev Growth Differ , vol.53 , Issue.4 , pp. 495-502
    • Wang, Y.1    Chen, C.L.2    Iijima, M.3
  • 9
    • 0037743735 scopus 로고    scopus 로고
    • Eukaryotic chemotaxis: Distinctions between directional sensing and polarization
    • Devreotes P, Janetopoulos C (2003) Eukaryotic chemotaxis: Distinctions between directional sensing and polarization. J Biol Chem 278(23):20445-20448.
    • (2003) J Biol Chem , vol.278 , Issue.23 , pp. 20445-20448
    • Devreotes, P.1    Janetopoulos, C.2
  • 10
    • 54549104845 scopus 로고    scopus 로고
    • Crosstalk between small GTPases and polarity proteins in cell polarization
    • Iden S, Collard JG (2008) Crosstalk between small GTPases and polarity proteins in cell polarization. Nat Rev Mol Cell Biol 9(11):846-859.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.11 , pp. 846-859
    • Iden, S.1    Collard, J.G.2
  • 12
    • 0030729285 scopus 로고    scopus 로고
    • Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation
    • Xiao Z, Zhang N, Murphy DB, Devreotes PN (1997) Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation. J Cell Biol 139(2):365-374.
    • (1997) J Cell Biol , vol.139 , Issue.2 , pp. 365-374
    • Xiao, Z.1    Zhang, N.2    Murphy, D.B.3    Devreotes, P.N.4
  • 13
    • 0034635567 scopus 로고    scopus 로고
    • Localization of the G protein betagamma complex in living cells during chemotaxis
    • Jin T, Zhang N, Long Y, Parent CA, Devreotes PN (2000) Localization of the G protein betagamma complex in living cells during chemotaxis. Science 287(5455):1034-1036.
    • (2000) Science , vol.287 , Issue.5455 , pp. 1034-1036
    • Jin, T.1    Zhang, N.2    Long, Y.3    Parent, C.A.4    Devreotes, P.N.5
  • 14
    • 12844268483 scopus 로고    scopus 로고
    • Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium
    • Xu X, Meier-Schellersheim M, Jiao X, Nelson LE, Jin T (2005) Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium. Mol Biol Cell 16(2):676-688.
    • (2005) Mol Biol Cell , vol.16 , Issue.2 , pp. 676-688
    • Xu, X.1    Meier-Schellersheim, M.2    Jiao, X.3    Nelson, L.E.4    Jin, T.5
  • 15
    • 8444221934 scopus 로고    scopus 로고
    • Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
    • Sasaki AT, Chun C, Takeda K, Firtel RA (2004) Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J Cell Biol 167(3): 505-518.
    • (2004) J Cell Biol , vol.167 , Issue.3 , pp. 505-518
    • Sasaki, A.T.1    Chun, C.2    Takeda, K.3    Firtel, R.A.4
  • 16
    • 0032475863 scopus 로고    scopus 로고
    • G protein signaling events are activated at the leading edge of chemotactic cells
    • Parent CA, Blacklock BJ, Froehlich WM, Murphy DB, Devreotes PN (1998) G protein signaling events are activated at the leading edge of chemotactic cells. Cell 95(1): 81-91.
    • (1998) Cell , vol.95 , Issue.1 , pp. 81-91
    • Parent, C.A.1    Blacklock, B.J.2    Froehlich, W.M.3    Murphy, D.B.4    Devreotes, P.N.5
  • 17
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima M, Devreotes P (2002) Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109(5):599-610.
    • (2002) Cell , vol.109 , Issue.5 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 18
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • Funamoto S, Meili R, Lee S, Parry L, Firtel RA (2002) Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109(5): 611-623.
    • (2002) Cell , vol.109 , Issue.5 , pp. 611-623
    • Funamoto, S.1    Meili, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 19
    • 77954985337 scopus 로고    scopus 로고
    • Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis
    • Cai H, et al. (2010) Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis. J Cell Biol 190(2):233-245.
    • (2010) J Cell Biol , vol.190 , Issue.2 , pp. 233-245
    • Cai, H.1
  • 20
    • 2942687012 scopus 로고    scopus 로고
    • Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton
    • Janetopoulos C, Ma L, Devreotes PN, Iglesias PA (2004) Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton. Proc Natl Acad Sci USA 101(24): 8951-8956.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.24 , pp. 8951-8956
    • Janetopoulos, C.1    Ma, L.2    Devreotes, P.N.3    Iglesias, P.A.4
  • 21
    • 33746785265 scopus 로고    scopus 로고
    • Cellular asymmetry and individuality in directional sensing
    • Samadani A, Mettetal J, van Oudenaarden A (2006) Cellular asymmetry and individuality in directional sensing. Proc Natl Acad Sci USA 103(31):11549-11554.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.31 , pp. 11549-11554
    • Samadani, A.1    Mettetal, J.2    Van Oudenaarden, A.3
  • 22
    • 0034635513 scopus 로고    scopus 로고
    • Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
    • Servant G, et al. (2000) Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science 287(5455):1037-1040.
    • (2000) Science , vol.287 , Issue.5455 , pp. 1037-1040
    • Servant, G.1
  • 23
    • 82555187016 scopus 로고    scopus 로고
    • Dictyostelium chemotaxis: Essential Ras activation and accessory signalling pathways for amplification
    • Kortholt A, et al. (2011) Dictyostelium chemotaxis: Essential Ras activation and accessory signalling pathways for amplification. EMBO Rep 12(12):1273-1279.
    • (2011) EMBO Rep , vol.12 , Issue.12 , pp. 1273-1279
    • Kortholt, A.1
  • 24
    • 1942501586 scopus 로고    scopus 로고
    • Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis
    • Iijima M, Huang YE, Luo HR, Vazquez F, Devreotes PN (2004) Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis. J Biol Chem 279(16):16606-16613.
    • (2004) J Biol Chem , vol.279 , Issue.16 , pp. 16606-16613
    • Iijima, M.1    Huang, Y.E.2    Luo, H.R.3    Vazquez, F.4    Devreotes, P.N.5
  • 25
    • 54149103045 scopus 로고    scopus 로고
    • Spatiotemporal regulation of Ras activity provides directional sensing
    • Zhang S, Charest PG, Firtel RA (2008) Spatiotemporal regulation of Ras activity provides directional sensing. Curr Biol 18(20):1587-1593.
    • (2008) Curr Biol , vol.18 , Issue.20 , pp. 1587-1593
    • Zhang, S.1    Charest, P.G.2    Firtel, R.A.3
  • 26
    • 79952779502 scopus 로고    scopus 로고
    • Rho GTPases and their role in organizing the actin cytoskeleton
    • Sit ST, Manser E (2011) Rho GTPases and their role in organizing the actin cytoskeleton. J Cell Sci 124(Pt 5):679-683.
    • (2011) J Cell Sci , vol.124 , Issue.PART 5 , pp. 679-683
    • Sit, S.T.1    Manser, E.2
  • 27
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A (2005) Rho GTPases: Biochemistry and biology. Annu Rev Cell Dev Biol 21:247-269.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 28
    • 58149395054 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinases in cell migration
    • Cain RJ, Ridley AJ (2009) Phosphoinositide 3-kinases in cell migration. Biol Cell 101(1): 13-29.
    • (2009) Biol Cell , vol.101 , Issue.1 , pp. 13-29
    • Cain, R.J.1    Ridley, A.J.2
  • 29
    • 84857406235 scopus 로고    scopus 로고
    • PI3K signalling: The path to discovery and understanding
    • Vanhaesebroeck B, Stephens L, Hawkins P (2012) PI3K signalling: The path to discovery and understanding. Nat Rev Mol Cell Biol 13(3):195-203.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.3 , pp. 195-203
    • Vanhaesebroeck, B.1    Stephens, L.2    Hawkins, P.3
  • 30
    • 33646197411 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of RhoA activity in migrating cells
    • Pertz O, Hodgson L, Klemke RL, Hahn KM (2006) Spatiotemporal dynamics of RhoA activity in migrating cells. Nature 440(7087):1069-1072.
    • (2006) Nature , vol.440 , Issue.7087 , pp. 1069-1072
    • Pertz, O.1    Hodgson, L.2    Klemke, R.L.3    Hahn, K.M.4
  • 31
    • 33644865751 scopus 로고    scopus 로고
    • Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a self-organizing mechanism
    • Wong K, Pertz O, Hahn K, Bourne H (2006) Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a self-organizing mechanism. Proc Natl Acad Sci USA 103(10):3639-3644.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.10 , pp. 3639-3644
    • Wong, K.1    Pertz, O.2    Hahn, K.3    Bourne, H.4
  • 32
    • 0034644603 scopus 로고    scopus 로고
    • Localized Rac activation dynamics visualized in living cells
    • Kraynov VS, et al. (2000) Localized Rac activation dynamics visualized in living cells. Science 290(5490):333-337.
    • (2000) Science , vol.290 , Issue.5490 , pp. 333-337
    • Kraynov, V.S.1
  • 33
    • 33746648129 scopus 로고    scopus 로고
    • To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front
    • Van Keymeulen A, et al. (2006) To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front. J Cell Biol 174(3): 437-445.
    • (2006) J Cell Biol , vol.174 , Issue.3 , pp. 437-445
    • Van Keymeulen, A.1
  • 34
    • 4644266043 scopus 로고    scopus 로고
    • Activation of endogenous Cdc42 visualized in living cells
    • Nalbant P, Hodgson L, Kraynov V, Toutchkine A, Hahn KM (2004) Activation of endogenous Cdc42 visualized in living cells. Science 305(5690):1615-1619.
    • (2004) Science , vol.305 , Issue.5690 , pp. 1615-1619
    • Nalbant, P.1    Hodgson, L.2    Kraynov, V.3    Toutchkine, A.4    Hahn, K.M.5
  • 35
    • 33748276641 scopus 로고    scopus 로고
    • Rho GTPase signaling in Dictyostelium discoideum: Insights from the genome
    • Vlahou G, Rivero F (2006) Rho GTPase signaling in Dictyostelium discoideum: Insights from the genome. Eur J Cell Biol 85(9-10):947-959.
    • (2006) Eur J Cell Biol , vol.85 , Issue.9-10 , pp. 947-959
    • Vlahou, G.1    Rivero, F.2
  • 37
    • 38549092474 scopus 로고    scopus 로고
    • Membrane recognition by phospholipid-binding domains
    • Lemmon MA (2008) Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol 9(2):99-111.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.2 , pp. 99-111
    • Lemmon, M.A.1
  • 38
    • 77955365645 scopus 로고    scopus 로고
    • Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum
    • Zhang P, Wang Y, Sesaki H, Iijima M (2010) Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum. Proc Natl Acad Sci USA 107(26):11829-11834.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.26 , pp. 11829-11834
    • Zhang, P.1    Wang, Y.2    Sesaki, H.3    Iijima, M.4
  • 39
    • 84863011642 scopus 로고    scopus 로고
    • Myosin i links PIP3 signaling to remodeling of the actin cytoskeleton in chemotaxis
    • Chen CL, Wang Y, Sesaki H, IijimaM (2012) Myosin I links PIP3 signaling to remodeling of the actin cytoskeleton in chemotaxis. Sci Signal 5(209):ra10.
    • (2012) Sci Signal , vol.5 , Issue.209
    • Chen, C.L.1    Wang, Y.2    Sesaki, H.3    Iijima, M.4
  • 40
    • 0346335806 scopus 로고    scopus 로고
    • Dynamic actin patterns and Arp2/3 assembly at the substrate-attached surface of motile cells
    • Bretschneider T, et al. (2004) Dynamic actin patterns and Arp2/3 assembly at the substrate-attached surface of motile cells. Curr Biol 14(1):1-10.
    • (2004) Curr Biol , vol.14 , Issue.1 , pp. 1-10
    • Bretschneider, T.1
  • 41
    • 0035282887 scopus 로고    scopus 로고
    • The Dictyostelium discoideum family of Rho-related proteins
    • Rivero F, Dislich H, Glöckner G, Noegel AA (2001) The Dictyostelium discoideum family of Rho-related proteins. Nucleic Acids Res 29(5):1068-1079.
    • (2001) Nucleic Acids Res , vol.29 , Issue.5 , pp. 1068-1079
    • Rivero, F.1    Dislich, H.2    Glöckner, G.3    Noegel, A.A.4
  • 42
    • 0029945192 scopus 로고    scopus 로고
    • A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis
    • Larochelle DA, Vithalani KK, De Lozanne A (1996) A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis. J Cell Biol 133(6): 1321-1329.
    • (1996) J Cell Biol , vol.133 , Issue.6 , pp. 1321-1329
    • Larochelle, D.A.1    Vithalani, K.K.2    De Lozanne, A.3
  • 43
    • 0034698682 scopus 로고    scopus 로고
    • Dynacortin, a genetic link between equatorial contractility and global shape control discovered by library complementation of a Dictyostelium discoideum cytokinesis mutant
    • Robinson DN, Spudich JA (2000) Dynacortin, a genetic link between equatorial contractility and global shape control discovered by library complementation of a Dictyostelium discoideum cytokinesis mutant. J Cell Biol 150(4):823-838.
    • (2000) J Cell Biol , vol.150 , Issue.4 , pp. 823-838
    • Robinson, D.N.1    Spudich, J.A.2
  • 44
    • 79952352658 scopus 로고    scopus 로고
    • Dynamics of the Rho-family small GTPases in actin regulation and motility
    • Spiering D, Hodgson L (2011) Dynamics of the Rho-family small GTPases in actin regulation and motility. Cell Adhes Migr 5(2):170-180.
    • (2011) Cell Adhes Migr , vol.5 , Issue.2 , pp. 170-180
    • Spiering, D.1    Hodgson, L.2
  • 45
    • 0030950580 scopus 로고    scopus 로고
    • Role of Dictyostelium racE in cytokinesis: Mutational analysis and localization studies by use of green fluorescent protein
    • Larochelle DA, Vithalani KK, De Lozanne A (1997) Role of Dictyostelium racE in cytokinesis: Mutational analysis and localization studies by use of green fluorescent protein. Mol Biol Cell 8(5):935-944.
    • (1997) Mol Biol Cell , vol.8 , Issue.5 , pp. 935-944
    • Larochelle, D.A.1    Vithalani, K.K.2    De Lozanne, A.3
  • 46
    • 18344394166 scopus 로고    scopus 로고
    • Post-prenylation-processing enzymes as new targets in oncogenesis
    • Winter-Vann AM, Casey PJ (2005) Post-prenylation-processing enzymes as new targets in oncogenesis. Nat Rev Cancer 5(5):405-412.
    • (2005) Nat Rev Cancer , vol.5 , Issue.5 , pp. 405-412
    • Winter-Vann, A.M.1    Casey, P.J.2
  • 47
    • 84863508973 scopus 로고    scopus 로고
    • The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration
    • Kato K, et al. (2012) The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration. Mol Biol Cell 23(13):2593-2604.
    • (2012) Mol Biol Cell , vol.23 , Issue.13 , pp. 2593-2604
    • Kato, K.1
  • 48
    • 65449139489 scopus 로고    scopus 로고
    • The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis
    • Shi Y, et al. (2009) The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis. J Immunol 182(6):3837-3845.
    • (2009) J Immunol , vol.182 , Issue.6 , pp. 3837-3845
    • Shi, Y.1
  • 49
    • 78149361673 scopus 로고    scopus 로고
    • 14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis
    • Zhou Q, et al. (2010) 14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis. Curr Biol 20(21):1881-1889.
    • (2010) Curr Biol , vol.20 , Issue.21 , pp. 1881-1889
    • Zhou, Q.1
  • 50
    • 0032550181 scopus 로고    scopus 로고
    • A role for Dictyostelium racE in cortical tension and cleavage furrow progression
    • Gerald N, Dai J, Ting-Beall HP, De Lozanne A (1998) A role for Dictyostelium racE in cortical tension and cleavage furrow progression. J Cell Biol 141(2):483-492.
    • (1998) J Cell Biol , vol.141 , Issue.2 , pp. 483-492
    • Gerald, N.1    Dai, J.2    Ting-Beall, H.P.3    De Lozanne, A.4
  • 51
    • 50149083752 scopus 로고    scopus 로고
    • Mammalian Rho GTPases: New insights into their functions from in vivo studies
    • Heasman SJ, Ridley AJ (2008) Mammalian Rho GTPases: New insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 9(9):690-701.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.9 , pp. 690-701
    • Heasman, S.J.1    Ridley, A.J.2
  • 53
    • 69949185998 scopus 로고    scopus 로고
    • Coordination of Rho GTPase activities during cell protrusion
    • Machacek M, et al. (2009) Coordination of Rho GTPase activities during cell protrusion. Nature 461(7260):99-103.
    • (2009) Nature , vol.461 , Issue.7260 , pp. 99-103
    • Machacek, M.1
  • 54
    • 0042354714 scopus 로고    scopus 로고
    • Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
    • Xu J, et al. (2003) Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell 114(2):201-214.
    • (2003) Cell , vol.114 , Issue.2 , pp. 201-214
    • Xu, J.1
  • 55
    • 20244379418 scopus 로고    scopus 로고
    • Regulation of PTEN by Rho small GTPases
    • Li Z, et al. (2005) Regulation of PTEN by Rho small GTPases. Nat Cell Biol 7(4):399-404.
    • (2005) Nat Cell Biol , vol.7 , Issue.4 , pp. 399-404
    • Li, Z.1
  • 56
    • 77953145912 scopus 로고    scopus 로고
    • Spatio-temporal Rho GTPase signaling: Where are we now?
    • Pertz O (2010) Spatio-temporal Rho GTPase signaling: Where are we now? J Cell Sci 123(Pt 11):1841-1850.
    • (2010) J Cell Sci , vol.123 , Issue.PART 11 , pp. 1841-1850
    • Pertz, O.1
  • 57
    • 79959861118 scopus 로고    scopus 로고
    • Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation
    • Wang Y, et al. (2011) Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation. Mol Biol Cell 22(13):2270-2281.
    • (2011) Mol Biol Cell , vol.22 , Issue.13 , pp. 2270-2281
    • Wang, Y.1


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