-
2
-
-
77957259884
-
The signaling mechanisms underlying cell polarity and chemotaxis
-
Wang F (2009) The signaling mechanisms underlying cell polarity and chemotaxis. Cold Spring Harb Perspect Biol 1(4):a002980.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
, Issue.4
-
-
Wang, F.1
-
3
-
-
77951249100
-
Cell migration during morphogenesis
-
Aman A, Piotrowski T (2010) Cell migration during morphogenesis. Dev Biol 341(1): 20-33.
-
(2010)
Dev Biol
, vol.341
, Issue.1
, pp. 20-33
-
-
Aman, A.1
Piotrowski, T.2
-
4
-
-
73649114969
-
Molecular layers underlying cytoskeletal remodeling during cortical development
-
Heng JI, Chariot A, Nguyen L (2010) Molecular layers underlying cytoskeletal remodeling during cortical development. Trends Neurosci 33(1):38-47.
-
(2010)
Trends Neurosci
, vol.33
, Issue.1
, pp. 38-47
-
-
Heng, J.I.1
Chariot, A.2
Nguyen, L.3
-
5
-
-
70249116807
-
Actin dynamics at the leading edge: From simple machinery to complex networks
-
Insall RH, Machesky LM (2009) Actin dynamics at the leading edge: From simple machinery to complex networks. Dev Cell 17(3):310-322.
-
(2009)
Dev Cell
, vol.17
, Issue.3
, pp. 310-322
-
-
Insall, R.H.1
Machesky, L.M.2
-
6
-
-
68049083547
-
Random versus directionally persistent cell migration
-
Petrie RJ, Doyle AD, Yamada KM (2009) Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol 10(8):538-549.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.8
, pp. 538-549
-
-
Petrie, R.J.1
Doyle, A.D.2
Yamada, K.M.3
-
7
-
-
77952911072
-
Eukaryotic chemotaxis: A network of signaling pathways controls motility, directional sensing, and polarity
-
Swaney KF, Huang CH, Devreotes PN (2010) Eukaryotic chemotaxis: A network of signaling pathways controls motility, directional sensing, and polarity. Annu Rev Biophys 39:265-289.
-
(2010)
Annu Rev Biophys
, vol.39
, pp. 265-289
-
-
Swaney, K.F.1
Huang, C.H.2
Devreotes, P.N.3
-
8
-
-
79956143423
-
Signaling mechanisms for chemotaxis
-
Wang Y, Chen CL, Iijima M (2011) Signaling mechanisms for chemotaxis. Dev Growth Differ 53(4):495-502.
-
(2011)
Dev Growth Differ
, vol.53
, Issue.4
, pp. 495-502
-
-
Wang, Y.1
Chen, C.L.2
Iijima, M.3
-
9
-
-
0037743735
-
Eukaryotic chemotaxis: Distinctions between directional sensing and polarization
-
Devreotes P, Janetopoulos C (2003) Eukaryotic chemotaxis: Distinctions between directional sensing and polarization. J Biol Chem 278(23):20445-20448.
-
(2003)
J Biol Chem
, vol.278
, Issue.23
, pp. 20445-20448
-
-
Devreotes, P.1
Janetopoulos, C.2
-
10
-
-
54549104845
-
Crosstalk between small GTPases and polarity proteins in cell polarization
-
Iden S, Collard JG (2008) Crosstalk between small GTPases and polarity proteins in cell polarization. Nat Rev Mol Cell Biol 9(11):846-859.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.11
, pp. 846-859
-
-
Iden, S.1
Collard, J.G.2
-
12
-
-
0030729285
-
Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation
-
Xiao Z, Zhang N, Murphy DB, Devreotes PN (1997) Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation. J Cell Biol 139(2):365-374.
-
(1997)
J Cell Biol
, vol.139
, Issue.2
, pp. 365-374
-
-
Xiao, Z.1
Zhang, N.2
Murphy, D.B.3
Devreotes, P.N.4
-
13
-
-
0034635567
-
Localization of the G protein betagamma complex in living cells during chemotaxis
-
Jin T, Zhang N, Long Y, Parent CA, Devreotes PN (2000) Localization of the G protein betagamma complex in living cells during chemotaxis. Science 287(5455):1034-1036.
-
(2000)
Science
, vol.287
, Issue.5455
, pp. 1034-1036
-
-
Jin, T.1
Zhang, N.2
Long, Y.3
Parent, C.A.4
Devreotes, P.N.5
-
14
-
-
12844268483
-
Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium
-
Xu X, Meier-Schellersheim M, Jiao X, Nelson LE, Jin T (2005) Quantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in Dictyostelium. Mol Biol Cell 16(2):676-688.
-
(2005)
Mol Biol Cell
, vol.16
, Issue.2
, pp. 676-688
-
-
Xu, X.1
Meier-Schellersheim, M.2
Jiao, X.3
Nelson, L.E.4
Jin, T.5
-
15
-
-
8444221934
-
Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
-
Sasaki AT, Chun C, Takeda K, Firtel RA (2004) Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J Cell Biol 167(3): 505-518.
-
(2004)
J Cell Biol
, vol.167
, Issue.3
, pp. 505-518
-
-
Sasaki, A.T.1
Chun, C.2
Takeda, K.3
Firtel, R.A.4
-
16
-
-
0032475863
-
G protein signaling events are activated at the leading edge of chemotactic cells
-
Parent CA, Blacklock BJ, Froehlich WM, Murphy DB, Devreotes PN (1998) G protein signaling events are activated at the leading edge of chemotactic cells. Cell 95(1): 81-91.
-
(1998)
Cell
, vol.95
, Issue.1
, pp. 81-91
-
-
Parent, C.A.1
Blacklock, B.J.2
Froehlich, W.M.3
Murphy, D.B.4
Devreotes, P.N.5
-
17
-
-
0037205230
-
Tumor suppressor PTEN mediates sensing of chemoattractant gradients
-
Iijima M, Devreotes P (2002) Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109(5):599-610.
-
(2002)
Cell
, vol.109
, Issue.5
, pp. 599-610
-
-
Iijima, M.1
Devreotes, P.2
-
18
-
-
0037205265
-
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
-
Funamoto S, Meili R, Lee S, Parry L, Firtel RA (2002) Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109(5): 611-623.
-
(2002)
Cell
, vol.109
, Issue.5
, pp. 611-623
-
-
Funamoto, S.1
Meili, R.2
Lee, S.3
Parry, L.4
Firtel, R.A.5
-
19
-
-
77954985337
-
Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis
-
Cai H, et al. (2010) Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis. J Cell Biol 190(2):233-245.
-
(2010)
J Cell Biol
, vol.190
, Issue.2
, pp. 233-245
-
-
Cai, H.1
-
20
-
-
2942687012
-
Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton
-
Janetopoulos C, Ma L, Devreotes PN, Iglesias PA (2004) Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton. Proc Natl Acad Sci USA 101(24): 8951-8956.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.24
, pp. 8951-8956
-
-
Janetopoulos, C.1
Ma, L.2
Devreotes, P.N.3
Iglesias, P.A.4
-
21
-
-
33746785265
-
Cellular asymmetry and individuality in directional sensing
-
Samadani A, Mettetal J, van Oudenaarden A (2006) Cellular asymmetry and individuality in directional sensing. Proc Natl Acad Sci USA 103(31):11549-11554.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.31
, pp. 11549-11554
-
-
Samadani, A.1
Mettetal, J.2
Van Oudenaarden, A.3
-
22
-
-
0034635513
-
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
-
Servant G, et al. (2000) Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science 287(5455):1037-1040.
-
(2000)
Science
, vol.287
, Issue.5455
, pp. 1037-1040
-
-
Servant, G.1
-
23
-
-
82555187016
-
Dictyostelium chemotaxis: Essential Ras activation and accessory signalling pathways for amplification
-
Kortholt A, et al. (2011) Dictyostelium chemotaxis: Essential Ras activation and accessory signalling pathways for amplification. EMBO Rep 12(12):1273-1279.
-
(2011)
EMBO Rep
, vol.12
, Issue.12
, pp. 1273-1279
-
-
Kortholt, A.1
-
24
-
-
1942501586
-
Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis
-
Iijima M, Huang YE, Luo HR, Vazquez F, Devreotes PN (2004) Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis. J Biol Chem 279(16):16606-16613.
-
(2004)
J Biol Chem
, vol.279
, Issue.16
, pp. 16606-16613
-
-
Iijima, M.1
Huang, Y.E.2
Luo, H.R.3
Vazquez, F.4
Devreotes, P.N.5
-
25
-
-
54149103045
-
Spatiotemporal regulation of Ras activity provides directional sensing
-
Zhang S, Charest PG, Firtel RA (2008) Spatiotemporal regulation of Ras activity provides directional sensing. Curr Biol 18(20):1587-1593.
-
(2008)
Curr Biol
, vol.18
, Issue.20
, pp. 1587-1593
-
-
Zhang, S.1
Charest, P.G.2
Firtel, R.A.3
-
26
-
-
79952779502
-
Rho GTPases and their role in organizing the actin cytoskeleton
-
Sit ST, Manser E (2011) Rho GTPases and their role in organizing the actin cytoskeleton. J Cell Sci 124(Pt 5):679-683.
-
(2011)
J Cell Sci
, vol.124
, Issue.PART 5
, pp. 679-683
-
-
Sit, S.T.1
Manser, E.2
-
27
-
-
27944479854
-
Rho GTPases: Biochemistry and biology
-
Jaffe AB, Hall A (2005) Rho GTPases: Biochemistry and biology. Annu Rev Cell Dev Biol 21:247-269.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 247-269
-
-
Jaffe, A.B.1
Hall, A.2
-
28
-
-
58149395054
-
Phosphoinositide 3-kinases in cell migration
-
Cain RJ, Ridley AJ (2009) Phosphoinositide 3-kinases in cell migration. Biol Cell 101(1): 13-29.
-
(2009)
Biol Cell
, vol.101
, Issue.1
, pp. 13-29
-
-
Cain, R.J.1
Ridley, A.J.2
-
30
-
-
33646197411
-
Spatiotemporal dynamics of RhoA activity in migrating cells
-
Pertz O, Hodgson L, Klemke RL, Hahn KM (2006) Spatiotemporal dynamics of RhoA activity in migrating cells. Nature 440(7087):1069-1072.
-
(2006)
Nature
, vol.440
, Issue.7087
, pp. 1069-1072
-
-
Pertz, O.1
Hodgson, L.2
Klemke, R.L.3
Hahn, K.M.4
-
31
-
-
33644865751
-
Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a self-organizing mechanism
-
Wong K, Pertz O, Hahn K, Bourne H (2006) Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a self-organizing mechanism. Proc Natl Acad Sci USA 103(10):3639-3644.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.10
, pp. 3639-3644
-
-
Wong, K.1
Pertz, O.2
Hahn, K.3
Bourne, H.4
-
32
-
-
0034644603
-
Localized Rac activation dynamics visualized in living cells
-
Kraynov VS, et al. (2000) Localized Rac activation dynamics visualized in living cells. Science 290(5490):333-337.
-
(2000)
Science
, vol.290
, Issue.5490
, pp. 333-337
-
-
Kraynov, V.S.1
-
33
-
-
33746648129
-
To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front
-
Van Keymeulen A, et al. (2006) To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front. J Cell Biol 174(3): 437-445.
-
(2006)
J Cell Biol
, vol.174
, Issue.3
, pp. 437-445
-
-
Van Keymeulen, A.1
-
34
-
-
4644266043
-
Activation of endogenous Cdc42 visualized in living cells
-
Nalbant P, Hodgson L, Kraynov V, Toutchkine A, Hahn KM (2004) Activation of endogenous Cdc42 visualized in living cells. Science 305(5690):1615-1619.
-
(2004)
Science
, vol.305
, Issue.5690
, pp. 1615-1619
-
-
Nalbant, P.1
Hodgson, L.2
Kraynov, V.3
Toutchkine, A.4
Hahn, K.M.5
-
35
-
-
33748276641
-
Rho GTPase signaling in Dictyostelium discoideum: Insights from the genome
-
Vlahou G, Rivero F (2006) Rho GTPase signaling in Dictyostelium discoideum: Insights from the genome. Eur J Cell Biol 85(9-10):947-959.
-
(2006)
Eur J Cell Biol
, vol.85
, Issue.9-10
, pp. 947-959
-
-
Vlahou, G.1
Rivero, F.2
-
36
-
-
33751297031
-
Signalling through Class i PI3Ks in mammalian cells
-
Hawkins PT, Anderson KE, Davidson K, Stephens LR (2006) Signalling through Class I PI3Ks in mammalian cells. Biochem Soc Trans 34(Pt 5):647-662.
-
(2006)
Biochem Soc Trans
, vol.34
, Issue.PART 5
, pp. 647-662
-
-
Hawkins, P.T.1
Anderson, K.E.2
Davidson, K.3
Stephens, L.R.4
-
37
-
-
38549092474
-
Membrane recognition by phospholipid-binding domains
-
Lemmon MA (2008) Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol 9(2):99-111.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.2
, pp. 99-111
-
-
Lemmon, M.A.1
-
38
-
-
77955365645
-
Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum
-
Zhang P, Wang Y, Sesaki H, Iijima M (2010) Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum. Proc Natl Acad Sci USA 107(26):11829-11834.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.26
, pp. 11829-11834
-
-
Zhang, P.1
Wang, Y.2
Sesaki, H.3
Iijima, M.4
-
39
-
-
84863011642
-
Myosin i links PIP3 signaling to remodeling of the actin cytoskeleton in chemotaxis
-
Chen CL, Wang Y, Sesaki H, IijimaM (2012) Myosin I links PIP3 signaling to remodeling of the actin cytoskeleton in chemotaxis. Sci Signal 5(209):ra10.
-
(2012)
Sci Signal
, vol.5
, Issue.209
-
-
Chen, C.L.1
Wang, Y.2
Sesaki, H.3
Iijima, M.4
-
40
-
-
0346335806
-
Dynamic actin patterns and Arp2/3 assembly at the substrate-attached surface of motile cells
-
Bretschneider T, et al. (2004) Dynamic actin patterns and Arp2/3 assembly at the substrate-attached surface of motile cells. Curr Biol 14(1):1-10.
-
(2004)
Curr Biol
, vol.14
, Issue.1
, pp. 1-10
-
-
Bretschneider, T.1
-
41
-
-
0035282887
-
The Dictyostelium discoideum family of Rho-related proteins
-
Rivero F, Dislich H, Glöckner G, Noegel AA (2001) The Dictyostelium discoideum family of Rho-related proteins. Nucleic Acids Res 29(5):1068-1079.
-
(2001)
Nucleic Acids Res
, vol.29
, Issue.5
, pp. 1068-1079
-
-
Rivero, F.1
Dislich, H.2
Glöckner, G.3
Noegel, A.A.4
-
42
-
-
0029945192
-
A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis
-
Larochelle DA, Vithalani KK, De Lozanne A (1996) A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis. J Cell Biol 133(6): 1321-1329.
-
(1996)
J Cell Biol
, vol.133
, Issue.6
, pp. 1321-1329
-
-
Larochelle, D.A.1
Vithalani, K.K.2
De Lozanne, A.3
-
43
-
-
0034698682
-
Dynacortin, a genetic link between equatorial contractility and global shape control discovered by library complementation of a Dictyostelium discoideum cytokinesis mutant
-
Robinson DN, Spudich JA (2000) Dynacortin, a genetic link between equatorial contractility and global shape control discovered by library complementation of a Dictyostelium discoideum cytokinesis mutant. J Cell Biol 150(4):823-838.
-
(2000)
J Cell Biol
, vol.150
, Issue.4
, pp. 823-838
-
-
Robinson, D.N.1
Spudich, J.A.2
-
44
-
-
79952352658
-
Dynamics of the Rho-family small GTPases in actin regulation and motility
-
Spiering D, Hodgson L (2011) Dynamics of the Rho-family small GTPases in actin regulation and motility. Cell Adhes Migr 5(2):170-180.
-
(2011)
Cell Adhes Migr
, vol.5
, Issue.2
, pp. 170-180
-
-
Spiering, D.1
Hodgson, L.2
-
45
-
-
0030950580
-
Role of Dictyostelium racE in cytokinesis: Mutational analysis and localization studies by use of green fluorescent protein
-
Larochelle DA, Vithalani KK, De Lozanne A (1997) Role of Dictyostelium racE in cytokinesis: Mutational analysis and localization studies by use of green fluorescent protein. Mol Biol Cell 8(5):935-944.
-
(1997)
Mol Biol Cell
, vol.8
, Issue.5
, pp. 935-944
-
-
Larochelle, D.A.1
Vithalani, K.K.2
De Lozanne, A.3
-
46
-
-
18344394166
-
Post-prenylation-processing enzymes as new targets in oncogenesis
-
Winter-Vann AM, Casey PJ (2005) Post-prenylation-processing enzymes as new targets in oncogenesis. Nat Rev Cancer 5(5):405-412.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.5
, pp. 405-412
-
-
Winter-Vann, A.M.1
Casey, P.J.2
-
47
-
-
84863508973
-
The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration
-
Kato K, et al. (2012) The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration. Mol Biol Cell 23(13):2593-2604.
-
(2012)
Mol Biol Cell
, vol.23
, Issue.13
, pp. 2593-2604
-
-
Kato, K.1
-
48
-
-
65449139489
-
The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis
-
Shi Y, et al. (2009) The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis. J Immunol 182(6):3837-3845.
-
(2009)
J Immunol
, vol.182
, Issue.6
, pp. 3837-3845
-
-
Shi, Y.1
-
49
-
-
78149361673
-
14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis
-
Zhou Q, et al. (2010) 14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis. Curr Biol 20(21):1881-1889.
-
(2010)
Curr Biol
, vol.20
, Issue.21
, pp. 1881-1889
-
-
Zhou, Q.1
-
50
-
-
0032550181
-
A role for Dictyostelium racE in cortical tension and cleavage furrow progression
-
Gerald N, Dai J, Ting-Beall HP, De Lozanne A (1998) A role for Dictyostelium racE in cortical tension and cleavage furrow progression. J Cell Biol 141(2):483-492.
-
(1998)
J Cell Biol
, vol.141
, Issue.2
, pp. 483-492
-
-
Gerald, N.1
Dai, J.2
Ting-Beall, H.P.3
De Lozanne, A.4
-
51
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
Heasman SJ, Ridley AJ (2008) Mammalian Rho GTPases: New insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 9(9):690-701.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
53
-
-
69949185998
-
Coordination of Rho GTPase activities during cell protrusion
-
Machacek M, et al. (2009) Coordination of Rho GTPase activities during cell protrusion. Nature 461(7260):99-103.
-
(2009)
Nature
, vol.461
, Issue.7260
, pp. 99-103
-
-
Machacek, M.1
-
54
-
-
0042354714
-
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
-
Xu J, et al. (2003) Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell 114(2):201-214.
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 201-214
-
-
Xu, J.1
-
55
-
-
20244379418
-
Regulation of PTEN by Rho small GTPases
-
Li Z, et al. (2005) Regulation of PTEN by Rho small GTPases. Nat Cell Biol 7(4):399-404.
-
(2005)
Nat Cell Biol
, vol.7
, Issue.4
, pp. 399-404
-
-
Li, Z.1
-
56
-
-
77953145912
-
Spatio-temporal Rho GTPase signaling: Where are we now?
-
Pertz O (2010) Spatio-temporal Rho GTPase signaling: Where are we now? J Cell Sci 123(Pt 11):1841-1850.
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 11
, pp. 1841-1850
-
-
Pertz, O.1
-
57
-
-
79959861118
-
Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation
-
Wang Y, et al. (2011) Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation. Mol Biol Cell 22(13):2270-2281.
-
(2011)
Mol Biol Cell
, vol.22
, Issue.13
, pp. 2270-2281
-
-
Wang, Y.1
|