Acid-degradable polymer-caged lipoplex (PCL) platform for siRNA delivery: Facile cellular triggered release of siRNA

Journal of the American Chemical Society

Volumn 135, Issue 47, 2013, Pages 17655-17658

  Hong, Bong Jin ^a   Chipre, Anthony J ^a   Nguyen, Sonbinh T ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR INTERNALIZATION; ENDOSOMAL ESCAPES; ENHANCED GREEN FLUORESCENT PROTEIN; IN-VITRO TESTING; PH-RESPONSIVE POLYMER; SIRNA DELIVERY; SMALL INTERFERING RNA (SIRNA); TRIGGERED RELEASE;

BIOCOMPATIBILITY; LIPOSOMES; POLYMERS; RNA;

LOADING;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CHOLESTEROL; DOUBLE STRANDED DNA; ENHANCED GREEN FLUORESCENT PROTEIN; LIPID; LIPOFECTAMINE; MACROGOL; NANOCARRIER; POLYACRYLIC ACID; POLYMER; SMALL INTERFERING RNA;

ACIDITY; ARTICLE; BIOCOMPATIBILITY; CANCER CELL; CONFOCAL LASER MICROSCOPY; CROSS LINKING; CYTOTOXICITY; DEGRADATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENDOSOME; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; INTERNALIZATION; LYSOSOME; NANOTECHNOLOGY; PARTICLE SIZE; PH; POLYMER CAGED LIPOPLEX;

CELL LINE, TUMOR; DELAYED-ACTION PREPARATIONS; ENDOSOMES; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROGEN-ION CONCENTRATION; POLYMERS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84889262006     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja404491r     Document Type: Article

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