Polymer-caged nanobins for synergistic cisplatin-doxorubicin combination chemotherapy

Journal of the American Chemical Society

Volumn 132, Issue 48, 2010, Pages 17130-17138

  Lee, Sang Min ^a   O'Halloran, Thomas V ^a   Nguyen, Sonbinh T ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; CANCER TREATMENT; CHARGE POTENTIALS; CIS-PLATIN; COMBINATION CHEMOTHERAPY; CYTOTOXIC AGENTS; DELIVERY VEHICLE; DOXORUBICIN; MULTICOMPONENTS; NANO SCALE; PH-RESPONSIVE; POLYMER SHELL; PRODRUGS; SINGLE POLYMERS;

CHEMOTHERAPY; CYTOTOXICITY; PLATINUM; PLATINUM COMPOUNDS; POLYMERS;

DRUG DOSAGE;

CISPLATIN; CISPLATIN PLUS DOXORUBICIN; DOXORUBICIN; LIPOSOME; NANOCARRIER; POLYMER CAGED NANOBIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG FORMULATION; DRUG POTENTIATION; DRUG SYNTHESIS; ENCAPSULATION; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CAPSULES; CELL LINE, TUMOR; CISPLATIN; DOXORUBICIN; DRUG CARRIERS; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ENDOCYTOSIS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPIDS; NANOTECHNOLOGY; PLATINUM; POLYMERS;

EID: 78650077255     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja107333g     Document Type: Article

References (50)

1. Szakacs, G., Paterson, J. K., Ludwig, J. A., Booth-Genthe, C., and Gottesman, M. M. Nat. Rev. Drug Discovery 2006, 5, 219-234
2. Jia, J., Zhu, F., Ma, X., Cao, Z. W., Li, Y. X., and Chen, Y. Z. Nat. Rev. Drug Discovery 2009, 8, 111-128
3. Minotti, G., Menna, P., Salvatorelli, E., Cairo, G., and Gianni, L. Pharmacol. Rev. 2004, 56, 185-229
4. Wang, D. and Lippard, S. J. Nat. Rev. Drug Discovery 2005, 4, 307-320
5. Kelland, L. Nat. Rev. Cancer 2007, 7, 573-584
6. Martoni, A., Bellucco, A., Canova, N., and Pannuti, F. Oncology 1989, 46, 109-116
7. Nielsen, D., Dombernowsky, P., Larsen, S. K., Hansen, O. P., and Skovsgaard, T. Cancer Chemother. Pharmacol. 2000, 46, 459-466
8. Thigpen, J. T., Brady, M. F., Homesley, H. D., Malfetano, J., DuBeshter, B., Burger, R. A., and Liao, S. J. Clin. Oncol. 2004, 22, 3902-3908
9. Nitiss, J. L. Nat. Rev. Cancer 2009, 9, 338-350
10. Bigioni, M., Benzo, A., Irrissuto, C., Lopez, G., Curatella, B., Maggi, C., Manzini, S., Crea, A., Caroli, S., Cubadda, F., and Binaschi, M. Cancer Chemother. Pharmacol. 2008, 62, 621-629
11. Chou, T.-C. and Talalay, P. Trends Pharmacol. Sci. 1983, 4, 450-454
12. Berenbaum, M. C. Pharmacol. Rev 1989, 41, 93-141
13. Zhao, L., Wientjes, M. G., and Au, J. L.-S. Clin. Cancer Res. 2004, 10, 7994-8004
14. Eder, J. P., Jr., Chan, V. T. W., Ng, S.-W., Rizvi, N. A., Zacharoulis, S., Teicher, B. A., and Schnipper, L. E. Cancer Res. 1995, 55, 6109-6116
15. Ali-Osman, F., Berger, M. S., Rajagopal, S., Spence, A., and Livingston, R. B. Cancer Res. 1993, 53, 5663-5668
16. Saleem, A., Ibrahim, N., Patel, M., Li, X.-G., Gupta, E., Mendoza, J., Pantazis, P., and Rubin, E. H. Cancer Res. 1997, 57, 5100-5106
17. Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., and Langer, R. Nat. Nanotechnol. 2007, 2, 751-760
18. Davis, M. E., Chen, Z., and Shin, D. M. Nat. Rev. Drug Discovery 2008, 7, 771-782
19. Waterhouse, D. N., Tardi, P. G., Mayer, L. D., and Bally, M. B. Drug Safety 2001, 24, 903-920
20. Lyass, O., Hubert, A., and Gabizon, A. A. Clin. Cancer Res. 2001, 7, 3040-3046
21. Ferrero, J.-M., Weber, B., Geay, J.-F., Lepille, D., Orfeuvre, H., Combe, M., Mayer, F., Leduc, B., Bourgeois, H., Paraiso, D., and Pujade-Lauraine, E. Ann. Oncol. 2007, 18, 263-268
22. Rapoport, B. L., Vorobiof, D. A., Slabber, C., Alberts, A. S., Hlophe, H. S., and Mohammed, C. Int. J. Gynecol. Cancer 2009, 19, 1137-1141
23. Lee, S.-M., Chen, H., O'Halloran, T. V., and Nguyen, S. T. J. Am. Chem. Soc. 2009, 131, 9311-9320
24. Lee, S.-M., Chen, H., Dettmer, C. M., O'Halloran, T. V., and Nguyen, S. T. J. Am. Chem. Soc. 2007, 129, 15096-15097
25. Tannock, I. F. and Rotin, D. Cancer Res. 1989, 49, 4373-4384
26. Li, S.-D. and Huang, L. Mol. Pharmaceutics 2008, 5, 496-504
27. Bandak, S., Goren, D., Horowitz, A., Tzemach, D., and Gabizon, A. Anti-Cancer Drugs 1999, 10, 911-920
28. Zamboni, W., Gervais, A., Egorin, M., Schellens, J. M., Zuhowski, E., Pluim, D., Joseph, E., Hamburger, D., Working, P., Colbern, G., Tonda, M., Potter, D., and Eiseman, J. Cancer Chemother. Pharmacol. 2004, 53, 329-336
29. Harrington, K. J., Lewanski, C. R., Northcote, A. D., Whittaker, J., Wellbank, H., Vile, R. G., Peters, A. M., and Stewart, J. S. W. Ann. Oncol. 2001, 12, 493-496
30. Kim, E. S., Lu, C., Khuri, F. R., Tonda, M., Glisson, B. S., Liu, D., Jung, M., Hong, W. K., and Herbst, R. S. Lung Cancer 2001, 34, 427-432
31. Casey, J. R., Grinstein, S., and Orlowski, J. Nat. Rev. Mol. Cell Biol. 2010, 11, 50-61
32. Appleton, T. G., Hall, J. R., and Prenzler, P. D. Inorg. Chem. 1989, 28, 815-819
33. Rice, J. R., Gerberich, J. L., Nowotnik, D. P., and Howell, S. B. Clin. Cancer Res. 2006, 12, 2248-2254
34. Yde, C. W. and Issinger, O.-G. Int. J. Oncol. 2006, 29, 1397-1404
35. Miller, C. R., Bondurant, B., McLean, S. D., McGovern, K. A., and O'Brien, D. F. Biochemistry 1998, 37, 12875-12883
36. Savic, R., Luo, L., Eisenberg, A., and Maysinger, D. Science 2003, 300, 615-618
37. VanEngeland, M., Nieland, L. J. W., Ramaekers, F. C. S., Schutte, B., and Reutelingsperger, C. P. M. Cytometry 1998, 31, 1-9
38. We note that the mode of cisplatin-induced cell death changed from apoptosis to necrosis above the threshold concentration of cisplatin, due to the significant damage of proteins related to the apoptotic process, ultimately leading to necrotic cell death. See ref 39.
39. Jung, Y. and Lippard, S. J. Chem. Rev. 2007, 107, 1387-1407
40. Burger, K. N. J., Staffhorst, R. W. H. M., de Vijlder, H. C., Velinova, M. J., Bomans, P. H., Frederik, P. M., and de Kruijff, B. Nat. Med. 2002, 8, 81-84
41. Maeda, H., Wu, J., Sawa, T., Matsumura, Y., and Hori, K. J. Controlled Release 2000, 65, 271-284
42. Hamelers, I. H. L., van Loenen, E., Staffhorst, R. W. H. M., de Kruijff, B., and de Kroon, A. I. P. M. Mol. Cancer Ther. 2006, 5, 2007-2012
43. Dhar, S., Gu, F. X., Langer, R., Farokhzad, O. C., and Lippard, S. J. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 17356-17361
44. Feazell, R. P., Nakayama-Ratchford, N., Dai, H., and Lippard, S. J. J. Am. Chem. Soc. 2007, 129, 8438-8439
45. Ahn, R. W., Chen, F., Chen, H., Stern, S. T., Clogston, J. D., Patri, A. K., Raja, M. R., Swindell, E. P., Parimi, V., Cryns, V. L., and O'Halloran, T. V. Clin. Cancer Res. 2010, 16, 3607-3617
46. Chen, H., Pazicni, S., Krett, N. L., Ahn, R. W., Penner-Hahn, J. E., Rosen, S. T., and O'Halloran, T. V. Angew. Chem., Int. Ed. 2009, 48, 9295-9299
47. Stock, R. S. and Ray, W. H. J. Polym. Sci., Part B: Polym. Phys. 1985, 23, 1393-1447
48. Appleton, T. G., Hall, J. R., Neale, D. W., and Thompson, C. S. M. Inorg. Chem. 1990, 29, 3985-3990
49. Haran, G., Cohen, R., Bar, L. K., and Barenholz, Y. Biochim. Biophys. Acta 1993, 1151, 201-215
50. Lee, S.-M., Ahn, R. W., Chen, F., Fought, A. J., O'Halloran, T. V., Cryns, V. L., and Nguyen, S. T. ACS Nano 2010, 4, 4971 - 4978.