Polyphosphonium polymers for siRNA delivery: An efficient and nontoxic alternative to polyammonium carriers

Journal of the American Chemical Society

Volumn 134, Issue 4, 2012, Pages 1902-1905

  Ornelas Megiatto, Cátia ^a   Wich, Peter R ^a   Fréchet, Jean M J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL SUBSTITUENT; CELL VIABILITY; GENE DELIVERY SYSTEMS; NON-TOXIC ALTERNATIVES; PHOSPHONIUM CATIONS; POLYAMMONIUM; POLYPLEXES; POSITIVELY CHARGED; SIRNA DELIVERY; TRANSFECTION EFFICIENCY;

AMMONIUM COMPOUNDS; EFFICIENCY; GENE THERAPY; GENE TRANSFER; MOLECULAR BIOLOGY; RNA; TOXICITY;

POLYMERS;

DRUG CARRIER; PHOSPHONIUM DERIVATIVE; POLYMER; SMALL INTERFERING RNA;

ARTICLE; GENE DELIVERY SYSTEM;

CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS; QUATERNARY AMMONIUM COMPOUNDS; RNA, SMALL INTERFERING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84856480640     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja207366k     Document Type: Article

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