Design and synthesis of P1-P3 macrocyclic tertiary-alcohol-comprising HIV-1 protease inhibitors

Journal of Medicinal Chemistry

Volumn 56, Issue 22, 2013, Pages 8999-9007

  Joshi, Advait ^a   Véron, Jean Baptiste ^a   Unge, Johan ^b   Rosenquist, Åsa ^c   Wallberg, Hans ^c   Samuelsson, Bertil ^c   Hallberg, Anders ^a   Larhed, Mats ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c MEDIVIR AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ATAZANAVIR; MACROCYCLIC COMPOUND;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; RING CLOSING METATHESIS;

ALCOHOLS; CHEMISTRY TECHNIQUES, SYNTHETIC; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HIV PROTEASE; HIV PROTEASE INHIBITORS; MACROCYCLIC COMPOUNDS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 84889261380     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400811d     Document Type: Article

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