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Volumn 2, Issue 8, 2011, Pages 701-709

HIV-1 protease inhibitors with a tertiary alcohol containing transition-state mimic and various P2 and P1′ substituents

(10) Öhrngren, Per a Wu, Xiongyu a Persson, Magnus a Ekegren, Jenny K a Wallberg, Hans b Vrang, Lotta b Rosenquist, Åsa b Samuelsson, Bertil b Unge, Torsten a Larhed, Mats a

a UPPSALA UNIVERSITY (Sweden)

b MEDIVIR AB (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; AMIDE; AMINO ACID DERIVATIVE; ATAZANAVIR; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; INDANOL AMIDE; TERTIARY ALCOHOL DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG PENETRATION; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; MATERIAL STATE; MOLECULAR INTERACTION; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; TRANSITION STATE; X RAY CRYSTALLOGRAPHY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79961140723 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c1md00077b Document Type: Article

Times cited : (13)

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