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Treatment of AIDS and HIV-related conditions-2002: Antiretroviral Therapy
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Results of a Phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naïve subjects
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Sanne I, Piliero P, Squires K, et al. Results of a Phase 2 clinical trial at 48 weeks (AI424-007): A dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naïve subjects. J Acquir Immune Defic Syndr. 2003;32:18-29.
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February; Chicago, Ill. Abstract 604
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O'Mara, E.M.1
Smith, J.2
Olsen, S.J.3
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5
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BMS-232632: A summary of multiple dose pharmacokinetic, food effect and drug interaction studies in healthy subjects
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February; San Francisco, Calif. Abstract 504
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O'Mara E, Mummaneni V, Randall D, et al. BMS-232632: A summary of multiple dose pharmacokinetic, food effect and drug interaction studies in healthy subjects. 7th Conference on Retroviruses and Opportunistic Infections; February 2000; San Francisco, Calif. Abstract 504.
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7th Conference on Retroviruses and Opportunistic Infections
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O'Mara, E.1
Mummaneni, V.2
Randall, D.3
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6
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0003313771
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Atazanavir: A once daily protease inhibitor with a superior lipid profile: Results of clinical trials beyond 48 weeks
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February; Seattle, Wash. Abstract 706
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Piliero P, Cahn P, Pantaleo G, et al. Atazanavir: a once daily protease inhibitor with a superior lipid profile: results of clinical trials beyond 48 weeks. 9th Conference on Retroviruses and Opportunistic Infections; February 2002; Seattle, Wash. Abstract 706.
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9th Conference on Retroviruses and Opportunistic Infections
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Piliero, P.1
Cahn, P.2
Pantaleo, G.3
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7
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Therapy with atazanavir plus saquinavir failing highly active antiretroviral therapy: A randomized comparative pilot trial
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In vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632
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Gong Y, Robinson BS, Rose RE, et al, In vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632. Antimicrob Agents Chemother. 2000;44(9):2319-2326.
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Activities of Atazanavir (BMS-232632) against a large panel of human immunodeficiency virus type 1 clinical isolates resistant to one or more approved protease inhibitors
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Colonno RJ, Thiry A, Limoli K, et al. Activities of Atazanavir (BMS-232632) against a large panel of human immunodeficiency virus type 1 clinical isolates resistant to one or more approved protease inhibitors. Antimicrob Agents Chemother. 2003;47(4):1324-1333.
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Antimicrob Agents Chemother
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Robinson BS, Riccardi KA, Gong Y, et al. BMS-232632, a highly potent human immunodeficiency virus protease inhibitor that can be used in combination with other available antiretroviral agents. Antimicrob Agents Chemother. 2000;44(8):2093-2099.
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Robinson, B.S.1
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Rational design of peptide based HIV proteinase inhibitors
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Roberts NA, Martin JA, Kinchington D, et al. Rational design of peptide based HIV proteinase inhibitors. Science. 1990;248:358-361.
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New anti-HIV agents and targets
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De Clercq E. New anti-HIV agents and targets. Medicinal Res Rev. 2002;22(6):531-565.
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Medicinal Res Rev
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De Clercq, E.1
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0242374022
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Emergence of Atazanavir resistance and maintenance of susceptibility to other PIs is associated with an 150L substitution in HIV protease
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February; Boston, Mass. Abstract 597
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Colonno RJ, Rose R, Cianci C, et al. Emergence of Atazanavir resistance and maintenance of susceptibility to other PIs is associated with an 150L substitution in HIV protease. 10th Conference on Retroviruses and Opportunistic Infections; February 2003; Boston, Mass. Abstract 597.
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10th Conference on Retroviruses and Opportunistic Infections
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Colonno, R.J.1
Rose, R.2
Cianci, C.3
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16
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0042778073
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Princeton, NJ: Bristol-Meyers Squibb; June
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Reyataz [package insert]. Princeton, NJ: Bristol-Meyers Squibb; June 2003.
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Reyataz [Package Insert]
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17
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0038543353
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Distinct cross-resistance profiles of the new protease inhibitors amprenavir, lopinavir, and atazanavir in a panel of clinical samples
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Schnell T, Schmidt B, Moschik G, et al. Distinct cross-resistance profiles of the new protease inhibitors amprenavir, lopinavir, and atazanavir in a panel of clinical samples. AIDS. 2003; 17 (8):1258-1261.
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Schnell, T.1
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Moschik, G.3
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Hollow-fiber evaluation of a new human immunodeficiency virus type 1 protease inhibitor, BMS-232632, for determination of the linked pharmacodynamic variable
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Drusano GL, Bilello JA, Preston SL. Hollow-fiber evaluation of a new human immunodeficiency virus type 1 protease inhibitor, BMS-232632, for determination of the linked pharmacodynamic variable. J Infect Dis. 2001; 183:1126-1129.
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19
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0003259764
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Comparative results (Phase II 48-week): BMS-232632, stavudine, lamuvidine as HAART for treatment-naïve HIV (+) patients (AI424-008)
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December; Chicago, Ill. Abstract 667
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Sanne I, Cahn L, Percival P, et al. Comparative results (Phase II 48-week): BMS-232632, stavudine, lamuvidine as HAART for treatment-naïve HIV (+) patients (AI424-008). 41st Interscience Conference on Antimicrobial Agents Chemotherapy; December 2001; Chicago, Ill. Abstract 667.
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(2001)
41st Interscience Conference on Antimicrobial Agents Chemotherapy
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Sanne, I.1
Cahn, L.2
Percival, P.3
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20
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0003267933
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Atazanavir (ATV) QD and Efavirenz (EFV) QD with fixed dose ZDV + 3TC: Comparison of antiviral efficacy and safety through week 24 (AI423-034)
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September; San Diego, Calif. Abstract H-1076
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Squires KE, Thiry A, Giordano M. Atazanavir (ATV) QD and Efavirenz (EFV) QD with fixed dose ZDV + 3TC: Comparison of antiviral efficacy and safety through week 24 (AI423-034). 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy; September 2002; San Diego, Calif. Abstract H-1076.
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(2002)
42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
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Squires, K.E.1
Thiry, A.2
Giordano, M.3
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21
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0347351926
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Antiviral efficacy, metabolic changes and safety of atazanavir (ATV) versus lopinavir/ritonavir (LPV/RTV) in combination with two NRTIs in patients who have experienced virological failure with prior PI containing regimens:24 week results from BMS AI424-043
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abstract 117
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Nieto-Cisneros L et al. Antiviral efficacy, metabolic changes and safety of atazanavir (ATV) versus lopinavir/ritonavir (LPV/RTV) in combination with two NRTIs in patients who have experienced virological failure with prior PI containing regimens:24 week results from BMS AI424-043. Antiviral Ther 2003;8(suppl 1):S212, abstract 117.
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Antiviral Ther
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Nieto-Cisneros, L.1
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22
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0346170040
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Efficacy and safety of atazanavir (ATV) with ritonavir (RTV) saquinavir (SQV) versus lopinavir/ritonavir (LPV/RTV) in combination with tenofovir (TFV) and one NRTI in patients who have experienced virologic failure on multiple HAART regimens: 16 Week results from BMS AI424-045
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July; Paris, France. Abstract 118
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Badaro R, et al. Efficacy and safety of atazanavir (ATV) with ritonavir (RTV) saquinavir (SQV) versus lopinavir/ritonavir (LPV/RTV) in combination with tenofovir (TFV) and one NRTI in patients who have experienced virologic failure on multiple HAART regimens: 16 week results from BMS AI424-045. 2nd IAS Conference on HIV Pathogenesis and Treatment; July 2003; Paris, France. Abstract 118.
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(2003)
2nd IAS Conference on HIV Pathogenesis and Treatment
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Badaro, R.1
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23
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0038022224
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Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or ATV: 108-week results of BMS study 008/044
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February; Boston, Mass. Abstract P555
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Murphy R, Pokrovsky V, Rozenbaum W, et al. Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or ATV: 108-week results of BMS study 008/044. 10th Conference on Retroviruses and Opportunistic Infections; February 2003; Boston, Mass. Abstract P555.
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(2003)
10th Conference on Retroviruses and Opportunistic Infections
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Murphy, R.1
Pokrovsky, V.2
Rozenbaum, W.3
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24
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0012562616
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Assessment of the effect of uridine diphosphate glucuronosyltransferase (UDP-GT) 1A1 geno-type on indirect bilirubin elevations in healthy subjects dosed with BMS-232632
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September; Toronto, Ontario, Canada
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O'Mara EM, Mummaneni V, Randall D, et al. Assessment of the effect of uridine diphosphate glucuronosyltransferase (UDP-GT) 1A1 geno-type on indirect bilirubin elevations in healthy subjects dosed with BMS-232632 [abstract]. 40th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 2000; Toronto, Ontario, Canada.
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(2000)
40th Interscience Conference on Antimicrobial Agents and Chemotherapy
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O'Mara, E.M.1
Mummaneni, V.2
Randall, D.3
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25
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0003313771
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Atazanavir: A once daily protease inhibitor with a superior lipid profile:results of clinical trials beyond week 48
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February; Seattle,Wash. Abstract 706
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Piliero P, Cahn P, Pantaleo G, et al. Atazanavir: A once daily protease inhibitor with a superior lipid profile:results of clinical trials beyond week 48. 9th Conference on Retroviruses and Opportunistic Infections; February 2002; Seattle,Wash. Abstract 706.
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(2002)
9th Conference on Retroviruses and Opportunistic Infections
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Piliero, P.1
Cahn, P.2
Pantaleo, G.3
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27
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0041944069
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Steady-state pharmacokinetic (PK) interaction study of atazanavir (ATV) with ritonavir (RTV) in healthy subjects
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September; San Diego, Calif. Abstract H-1716
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Agarwala S, et al. Steady-state pharmacokinetic (PK) interaction study of atazanavir (ATV) with ritonavir (RTV) in healthy subjects. 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy; September 2002; San Diego, Calif. Abstract H-1716.
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(2002)
42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
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Agarwala, S.1
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29
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0042945649
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Steady state pharmacokinetic interaction study of atazanavir (ATV) with efavirenz (EFV) and ritonavir (RTV) in healthy subjects
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February; Seattle, Wash. Abstract 444
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O'Mara E, Agarwala S, Randall D, et al. Steady state pharmacokinetic interaction study of atazanavir (ATV) with efavirenz (EFV) and ritonavir (RTV) in healthy subjects. 9th Conference on Retroviruses and Opportunistic Infections; February 2002; Seattle, Wash. Abstract 444.
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(2002)
9th Conference on Retroviruses and Opportunistic Infections
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O'Mara, E.1
Agarwala, S.2
Randall, D.3
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30
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0347982185
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Pharmacokinetic parameters of Atazanavir/ritonavir when combined to tenofovir in HIV infected patients with multiple treatment failures: A sub-study of puzzle 2-ANRS 107 trial
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February; Boston, Mass. Abstract 537
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Taburet AM, et al. Pharmacokinetic parameters of Atazanavir/ritonavir when combined to tenofovir in HIV infected patients with multiple treatment failures: a sub-study of puzzle 2-ANRS 107 trial. 10th Conference on Retroviruses and Opportunistic Infections; February 2003; Boston, Mass. Abstract 537.
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(2003)
10th Conference on Retroviruses and Opportunistic Infections
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Taburet, A.M.1
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31
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0042444801
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Steady-state pharmacokinetic (PK) interaction of atazanavir (ATV) with lamuvidine (3TC) and zidovudine (ZDV) in healthy subjects
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September; San Diego, Calif. Abstract H-1713
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Mummaneni V, et al. Steady-state pharmacokinetic (PK) interaction of atazanavir (ATV) with lamuvidine (3TC) and zidovudine (ZDV) in healthy subjects. 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy; September 2002; San Diego, Calif. Abstract H-1713.
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(2002)
42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
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Mummaneni, V.1
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32
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0042444801
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Steady-state (PK) interaction study of atazanavir (ATV) with clarithromycin (CLR) in healthy subjects
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September; San Diego, Calif. Abstract H-1717
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Mummaneni V, et al. Steady-state (PK) interaction study of atazanavir (ATV) with clarithromycin (CLR) in healthy subjects. 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy; September 2002; San Diego, Calif. Abstract H-1717.
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(2002)
42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
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Mummaneni, V.1
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33
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0042444800
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Pharmacokinetic (PK) effect of rifabutin (RIF) on atazanavir (ATV) with and without ritonavir (RTV) in healthy subjects
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February; Seattle, Wash. Abstract 445
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Agarwala S, Mummaneni V, Randall D, et al. Pharmacokinetic (PK) effect of rifabutin (RIF) on atazanavir (ATV) with and without ritonavir (RTV) in healthy subjects. 9th Conference on Retroviruses and Opportunistic Infections; February 2002; Seattle, Wash. Abstract 445.
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(2002)
9th Conference on Retroviruses and Opportunistic Infections
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Agarwala, S.1
Mummaneni, V.2
Randall, D.3
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34
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0346090858
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Steady state pharmacokinetic interaction study between BMS-232632 and ketoconazole in healthy subjects
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September; Toronto, Ontario, Canada. Abstract 1646
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O'Mara E, Randall D, Uderman H, et al. Steady state pharmacokinetic interaction study between BMS-232632 and ketoconazole in healthy subjects. 40th interscience Conference on Antimicrobial Agents and Chemotherapy; September 2000; Toronto, Ontario, Canada. Abstract 1646.
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(2000)
40th Interscience Conference on Antimicrobial Agents and Chemotherapy
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O'Mara, E.1
Randall, D.2
Uderman, H.3
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