High-speed optimization of inhibitors of the malarial proteases plasmepsin I and II

Journal of Combinatorial Chemistry

Volumn 5, Issue 4, 2003, Pages 456-464

  Nöteberg, Daniel ^a   Schaal, Wesley ^a   Hamelink, Elizabeth ^b   Vrang, Lotta ^b   Larhed, Mats ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b MEDIVIR AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

3 AZA 3 (BENZYLOXYCARBONYL) 2 (4 BROMOBENZYL) 6 [[(TERT BUTYLOXYCARBONYL)VALINYL]AMINO] 5 HYDROXY 7 PHENYLHEPTANOYL AMIDE; AMIDE; PLASMEPSIN I; PLASMEPSIN II; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG PURIFICATION; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN; PHYSICAL CHEMISTRY;

ANIMALS; ASPARTIC ENDOPEPTIDASES; BIPHENYL COMPOUNDS; CARBOXYLIC ACIDS; CATHEPSIN D; COMBINATORIAL CHEMISTRY TECHNIQUES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROWAVES; PEPTIDE LIBRARY; PLASMODIUM FALCIPARUM; PROTEASE INHIBITORS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141787013     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc0301014     Document Type: Article

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