Advances in the development of Rho-associated protein kinase (ROCK) inhibitors

Drug Discovery Today

Volumn 18, Issue 23-24, 2013, Pages 1323-1333

  Pan, Peichen ^a   Shen, Mingyun ^a   Yu, Huidong ^c   Li, Youyong ^a   Li, Dan ^b   Hou, Tingjun ^a,b  

^a SOOCHOW UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c International Business Incubator   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; AMA 0076; AR 12286; BA 210; DE 104; FASUDIL; HYDROXYFASUDIL; INS 117548; K 115; RHO KINASE; RHO KINASE INHIBITOR; RKI 1447; SAR 407899; UNCLASSIFIED DRUG; WF 536; Y 39983; PROTEIN KINASE INHIBITOR; ROCK1 PROTEIN, HUMAN; ROCK2 PROTEIN, HUMAN;

BRAIN ISCHEMIA; BRAIN VASOSPASM; CELL FUNCTION; CLINICAL TRIAL (TOPIC); DRUG ACTIVITY; DRUG STRUCTURE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME REGULATION; ENZYME STRUCTURE; ERECTILE DYSFUNCTION; GLAUCOMA; HUMAN; INTRAOCULAR HYPERTENSION; NONHUMAN; OPEN ANGLE GLAUCOMA; PROTEIN FAMILY; REVIEW; SPINAL CORD INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG DESIGN; METABOLISM;

ANIMALS; DRUG DESIGN; HUMANS; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES;

EID: 84889088178     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2013.09.010     Document Type: Review

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