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Volumn 123, Issue 1, 2009, Pages 218-223

Peripheral Delivery of a ROCK Inhibitor Improves Learning and Working Memory

Author keywords

aging; fasudil; learning; memory; ROCK

Indexed keywords

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; AGING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MAZE LEARNING; MEMORY, SHORT-TERM; RATS; RATS, INBRED F344; RHOA GTP-BINDING PROTEIN;

EID: 60549103537     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0014260     Document Type: Article
Times cited : (81)

References (49)
  • 2
    • 0033045993 scopus 로고    scopus 로고
    • Estradiol facilitates performance as working memory load increases
    • Bimonte H.A., and Denenberg V.H. Estradiol facilitates performance as working memory load increases. Psychoneuroendocrinology 24 (1999) 161-173
    • (1999) Psychoneuroendocrinology , vol.24 , pp. 161-173
    • Bimonte, H.A.1    Denenberg, V.H.2
  • 3
    • 0034052384 scopus 로고    scopus 로고
    • Sex differences in vicarious trial-and-error behavior during radial arm maze learning
    • Bimonte H.A., and Denenberg V.H. Sex differences in vicarious trial-and-error behavior during radial arm maze learning. Physiology and Behavior 68 (2000) 495-499
    • (2000) Physiology and Behavior , vol.68 , pp. 495-499
    • Bimonte, H.A.1    Denenberg, V.H.2
  • 4
    • 0037008357 scopus 로고    scopus 로고
    • Spatial memory testing decreases hippocampal amyloid precursor protein in young, but not aged, female rats
    • Bimonte H.A., Granholm A.C., Seo H., and Isacson O. Spatial memory testing decreases hippocampal amyloid precursor protein in young, but not aged, female rats. Neuroscience Letters 328 (2002) 50-54
    • (2002) Neuroscience Letters , vol.328 , pp. 50-54
    • Bimonte, H.A.1    Granholm, A.C.2    Seo, H.3    Isacson, O.4
  • 5
    • 0033826237 scopus 로고    scopus 로고
    • In two species, females exhibit superior working memory and inferior reference memory on the water radial-arm maze
    • Bimonte H.A., Hyde L.A., Hoplight B.J., and Denenberg V.H. In two species, females exhibit superior working memory and inferior reference memory on the water radial-arm maze. Physiology and Behavior 70 (2000) 311-317
    • (2000) Physiology and Behavior , vol.70 , pp. 311-317
    • Bimonte, H.A.1    Hyde, L.A.2    Hoplight, B.J.3    Denenberg, V.H.4
  • 6
    • 0037213030 scopus 로고    scopus 로고
    • Age-related deficits as working memory load increases: Relationships with growth factors
    • Bimonte H.A., Nelson M.E., and Granholm A.C. Age-related deficits as working memory load increases: Relationships with growth factors. Neurobiology of Aging 24 (2003) 37-48
    • (2003) Neurobiology of Aging , vol.24 , pp. 37-48
    • Bimonte, H.A.1    Nelson, M.E.2    Granholm, A.C.3
  • 7
    • 33745886533 scopus 로고    scopus 로고
    • Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle-aged ovariectomized female rats
    • Bimonte-Nelson H.A., Francis K.R., Umphlet C.D., and Granholm A.C. Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle-aged ovariectomized female rats. European Journal of Neuroscience 24 (2006) 229-242
    • (2006) European Journal of Neuroscience , vol.24 , pp. 229-242
    • Bimonte-Nelson, H.A.1    Francis, K.R.2    Umphlet, C.D.3    Granholm, A.C.4
  • 8
    • 0037450168 scopus 로고    scopus 로고
    • Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome
    • Bimonte-Nelson H.A., Hunter C.L., Nelson M.E., and Granholm A.C. Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome. Behavioural Brain Research 139 (2003) 47-57
    • (2003) Behavioural Brain Research , vol.139 , pp. 47-57
    • Bimonte-Nelson, H.A.1    Hunter, C.L.2    Nelson, M.E.3    Granholm, A.C.4
  • 9
    • 3242755749 scopus 로고    scopus 로고
    • Ovarian hormones and cognition in the aged female rat: II. Progesterone supplementation reverses the cognitive enhancing effects of ovariectomy
    • Bimonte-Nelson H.A., Singleton R.S., Williams B.J., and Granholm A.C. Ovarian hormones and cognition in the aged female rat: II. Progesterone supplementation reverses the cognitive enhancing effects of ovariectomy. Behavioral Neuroscience 118 (2004) 707-714
    • (2004) Behavioral Neuroscience , vol.118 , pp. 707-714
    • Bimonte-Nelson, H.A.1    Singleton, R.S.2    Williams, B.J.3    Granholm, A.C.4
  • 14
    • 48249112971 scopus 로고    scopus 로고
    • Role of Rho kinase pathway in chondroitin sulfate proteoglycan-mediated inhibition of neurite outgrowth in PC12 cells
    • Gopalakrishnan S.M., Teusch N., Imhof C., Bakker M.H., Schurdak M., Burns D.J., et al. Role of Rho kinase pathway in chondroitin sulfate proteoglycan-mediated inhibition of neurite outgrowth in PC12 cells. Journal of Neuroscience Research 86 (2008) 2214-2226
    • (2008) Journal of Neuroscience Research , vol.86 , pp. 2214-2226
    • Gopalakrishnan, S.M.1    Teusch, N.2    Imhof, C.3    Bakker, M.H.4    Schurdak, M.5    Burns, D.J.6
  • 15
    • 33845804228 scopus 로고    scopus 로고
    • Systemic availability of the active metabolite hydroxy-fasudil after administration of fasudil to different sites of the human gastrointestinal tract
    • Hinderling P.H., Karara A.H., Tao B., Pawula M., Wilding I., and Lu M. Systemic availability of the active metabolite hydroxy-fasudil after administration of fasudil to different sites of the human gastrointestinal tract. Journal of Clinical Pharmacology 47 (2007) 19-25
    • (2007) Journal of Clinical Pharmacology , vol.47 , pp. 19-25
    • Hinderling, P.H.1    Karara, A.H.2    Tao, B.3    Pawula, M.4    Wilding, I.5    Lu, M.6
  • 16
    • 12744255285 scopus 로고    scopus 로고
    • Therapeutic potential of rho-kinase inhibitors in cardiovascular diseases
    • Hirooka Y., and Shimokawa H. Therapeutic potential of rho-kinase inhibitors in cardiovascular diseases. American Journal of Cardiovascular Drugs 5 (2005) 31-39
    • (2005) American Journal of Cardiovascular Drugs , vol.5 , pp. 31-39
    • Hirooka, Y.1    Shimokawa, H.2
  • 17
    • 0032473584 scopus 로고    scopus 로고
    • Water version of the radial-arm maze: Learning in three inbred strains of mice
    • Hyde L.A., Hoplight B.J., and Denenberg V.H. Water version of the radial-arm maze: Learning in three inbred strains of mice. Brain Research 785 (1998) 236-244
    • (1998) Brain Research , vol.785 , pp. 236-244
    • Hyde, L.A.1    Hoplight, B.J.2    Denenberg, V.H.3
  • 18
    • 0034725155 scopus 로고    scopus 로고
    • Non-spatial water radial-arm maze learning in mice
    • Hyde L.A., Sherman G.F., and Denenberg V.H. Non-spatial water radial-arm maze learning in mice. Brain Research 863 (2000) 151-159
    • (2000) Brain Research , vol.863 , pp. 151-159
    • Hyde, L.A.1    Sherman, G.F.2    Denenberg, V.H.3
  • 19
    • 0021687512 scopus 로고
    • On the role of hippocampal connections in the performance of place and cue tasks: Comparisons with damage to hippocampus
    • Jarrard L.E., Okaichi H., Steward O., and Goldschmidt R.B. On the role of hippocampal connections in the performance of place and cue tasks: Comparisons with damage to hippocampus. Behavioral Neuroscience 98 (1984) 946-954
    • (1984) Behavioral Neuroscience , vol.98 , pp. 946-954
    • Jarrard, L.E.1    Okaichi, H.2    Steward, O.3    Goldschmidt, R.B.4
  • 20
    • 33847191058 scopus 로고    scopus 로고
    • Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats
    • Jiang B.H., Tawara S., Abe K., Takaki A., Fukumoto Y., and Shimokawa H. Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats. Journal of Cardiovascular Pharmacology 49 (2007) 85-89
    • (2007) Journal of Cardiovascular Pharmacology , vol.49 , pp. 85-89
    • Jiang, B.H.1    Tawara, S.2    Abe, K.3    Takaki, A.4    Fukumoto, Y.5    Shimokawa, H.6
  • 21
    • 50249184739 scopus 로고    scopus 로고
    • Temporal-spatial expression and novel biochemical properties of the memory-related protein KIBRA
    • Johannsen S., Duning K., Pavenstadt H., Kremerskothen J., and Boeckers T.M. Temporal-spatial expression and novel biochemical properties of the memory-related protein KIBRA. Neuroscience 155 (2008) 1165-1173
    • (2008) Neuroscience , vol.155 , pp. 1165-1173
    • Johannsen, S.1    Duning, K.2    Pavenstadt, H.3    Kremerskothen, J.4    Boeckers, T.M.5
  • 24
    • 0037079063 scopus 로고    scopus 로고
    • Fear memory formation involves pp. 190 RhoGAP and ROCK proteins through a GRB2-mediated complex
    • Lamprecht R., Farb C.R., and LeDoux J.E. Fear memory formation involves pp. 190 RhoGAP and ROCK proteins through a GRB2-mediated complex. Neuron 36 (2002) 727-738
    • (2002) Neuron , vol.36 , pp. 727-738
    • Lamprecht, R.1    Farb, C.R.2    LeDoux, J.E.3
  • 26
    • 34548638861 scopus 로고    scopus 로고
    • Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo
    • Lingor P., Teusch N., Schwarz K., Mueller R., Mack H., Bahr M., et al. Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo. Journal of Neurochemistry 103 (2007) 181-189
    • (2007) Journal of Neurochemistry , vol.103 , pp. 181-189
    • Lingor, P.1    Teusch, N.2    Schwarz, K.3    Mueller, R.4    Mack, H.5    Bahr, M.6
  • 27
    • 33745746346 scopus 로고    scopus 로고
    • Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells
    • Liu L.Z., Zhao H.L., Zuo J., Ho S.K., Chan J.C., Meng Y., et al. Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells. Molekuliarnaia Biologiia Cell 17 (2006) 2322-2330
    • (2006) Molekuliarnaia Biologiia Cell , vol.17 , pp. 2322-2330
    • Liu, L.Z.1    Zhao, H.L.2    Zuo, J.3    Ho, S.K.4    Chan, J.C.5    Meng, Y.6
  • 28
    • 33745801976 scopus 로고    scopus 로고
    • RhoA-kinase and myosin II are required for the maintenance of growth cone polarity and guidance by nerve growth factor
    • Loudon R.P., Silver L.D., Yee Jr. H.F., and Gallo G. RhoA-kinase and myosin II are required for the maintenance of growth cone polarity and guidance by nerve growth factor. Journal of Neurobiology 66 (2006) 847-867
    • (2006) Journal of Neurobiology , vol.66 , pp. 847-867
    • Loudon, R.P.1    Silver, L.D.2    Yee Jr., H.F.3    Gallo, G.4
  • 29
    • 0030480907 scopus 로고    scopus 로고
    • Spatial working memory and strategy formation in patients with frontal lobe excisions
    • Miotto E.C., Bullock P., Polkey C.E., and Morris R.G. Spatial working memory and strategy formation in patients with frontal lobe excisions. Cortex 32 (1996) 613-630
    • (1996) Cortex , vol.32 , pp. 613-630
    • Miotto, E.C.1    Bullock, P.2    Polkey, C.E.3    Morris, R.G.4
  • 30
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods 11 (1984) 47-60
    • (1984) Journal of Neuroscience Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 31
    • 41949123414 scopus 로고    scopus 로고
    • KIBRA gene variants are associated with episodic memory performance in subjective memory complaints
    • Nacmias B., Bessi V., Bagnoli S., Tedde A., Cellini E., Piccini C., et al. KIBRA gene variants are associated with episodic memory performance in subjective memory complaints. Neuroscience Letters 436 (2008) 145-147
    • (2008) Neuroscience Letters , vol.436 , pp. 145-147
    • Nacmias, B.1    Bessi, V.2    Bagnoli, S.3    Tedde, A.4    Cellini, E.5    Piccini, C.6
  • 32
    • 0027361126 scopus 로고
    • Effects of fasudil hydrochloride on cerebral blood flow in patients with chronic cerebral infarction
    • Nagata K., Kondoh Y., Satoh Y., Watahiki Y., Yokoyama E., Yuya H., et al. Effects of fasudil hydrochloride on cerebral blood flow in patients with chronic cerebral infarction. Clinical Neuropharmacology 16 (1993) 501-510
    • (1993) Clinical Neuropharmacology , vol.16 , pp. 501-510
    • Nagata, K.1    Kondoh, Y.2    Satoh, Y.3    Watahiki, Y.4    Yokoyama, E.5    Yuya, H.6
  • 36
    • 0025633723 scopus 로고
    • A further characterization of the spatial problem-solving deficit induced by lesions of the medial frontal cortex in the rat
    • Poucet B. A further characterization of the spatial problem-solving deficit induced by lesions of the medial frontal cortex in the rat. Behavioural Brain Research 41 (1990) 229-237
    • (1990) Behavioural Brain Research , vol.41 , pp. 229-237
    • Poucet, B.1
  • 37
    • 0025346907 scopus 로고
    • Septum and medial frontal cortex contribution to spatial problem-solving
    • Poucet B., and Herrmann T. Septum and medial frontal cortex contribution to spatial problem-solving. Behavioural Brain Research 37 (1990) 269-280
    • (1990) Behavioural Brain Research , vol.37 , pp. 269-280
    • Poucet, B.1    Herrmann, T.2
  • 39
    • 33747603649 scopus 로고    scopus 로고
    • ROCK inhibition produces anxiety-related behaviors in mice
    • in press, Berlin
    • Saitoh, A., Yamada, M., Kobayashi, S., Hirose, N., Honda, K., et al. (in press). ROCK inhibition produces anxiety-related behaviors in mice. Psychopharmacology (Berlin), 188, 1-11.
    • Psychopharmacology , vol.188 , pp. 1-11
    • Saitoh, A.1    Yamada, M.2    Kobayashi, S.3    Hirose, N.4    Honda, K.5
  • 40
    • 25444528940 scopus 로고    scopus 로고
    • Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1
    • Salhia B., Rutten F., Nakada M., Beaudry C., Berens M., Kwan A., et al. Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1. Cancer Research 65 (2005) 8792-8800
    • (2005) Cancer Research , vol.65 , pp. 8792-8800
    • Salhia, B.1    Rutten, F.2    Nakada, M.3    Beaudry, C.4    Berens, M.5    Kwan, A.6
  • 41
    • 33750015291 scopus 로고    scopus 로고
    • Preclinical research into cognition enhancers
    • Sarter M. Preclinical research into cognition enhancers. Trends in Pharmacological Sciences 27 (2006) 602-608
    • (2006) Trends in Pharmacological Sciences , vol.27 , pp. 602-608
    • Sarter, M.1
  • 42
    • 33846006516 scopus 로고    scopus 로고
    • Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils
    • Satoh S., Toshima Y., Ikegaki I., Iwasaki M., and Asano T. Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils. Brain Research 1128 (2007) 175-180
    • (2007) Brain Research , vol.1128 , pp. 175-180
    • Satoh, S.1    Toshima, Y.2    Ikegaki, I.3    Iwasaki, M.4    Asano, T.5
  • 43
    • 43849111330 scopus 로고    scopus 로고
    • KIBRA gene variants are associated with episodic memory in healthy elderly
    • Schaper K., Kolsch H., Popp J., Wagner M., and Jessen F. KIBRA gene variants are associated with episodic memory in healthy elderly. Neurobiology of Aging 29 (2008) 1123-1125
    • (2008) Neurobiology of Aging , vol.29 , pp. 1123-1125
    • Schaper, K.1    Kolsch, H.2    Popp, J.3    Wagner, M.4    Jessen, F.5
  • 44
    • 33847016103 scopus 로고    scopus 로고
    • Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation
    • Scott G.A., Arioka M., and Jacobs S.E. Lysophosphatidylcholine mediates melanocyte dendricity through PKCzeta activation. Journal of Investigative Dermatology 127 (2007) 668-675
    • (2007) Journal of Investigative Dermatology , vol.127 , pp. 668-675
    • Scott, G.A.1    Arioka, M.2    Jacobs, S.E.3
  • 45
    • 34548125816 scopus 로고    scopus 로고
    • Rapid erasure of long-term memory associations in the cortex by an inhibitor of PKM zeta
    • Shema R., Sacktor T.C., and Dudai Y. Rapid erasure of long-term memory associations in the cortex by an inhibitor of PKM zeta. Science 317 5840 (2007) 951-953
    • (2007) Science , vol.317 , Issue.5840 , pp. 951-953
    • Shema, R.1    Sacktor, T.C.2    Dudai, Y.3
  • 46
    • 17744417743 scopus 로고    scopus 로고
    • Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton
    • Uberall F., Hellbert K., Kampfer S., Maly K., Villunger A., Spitaler M., et al. Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton. Journal of Cell Biology 144 (1999) 413-425
    • (1999) Journal of Cell Biology , vol.144 , pp. 413-425
    • Uberall, F.1    Hellbert, K.2    Kampfer, S.3    Maly, K.4    Villunger, A.5    Spitaler, M.6
  • 47
    • 33646876458 scopus 로고    scopus 로고
    • Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells
    • Van Kolen K., and Slegers H. Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells. FEBS Journal 273 (2006) 1843-1854
    • (2006) FEBS Journal , vol.273 , pp. 1843-1854
    • Van Kolen, K.1    Slegers, H.2
  • 48
    • 32544443281 scopus 로고    scopus 로고
    • Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts
    • Woo S., and Gomez T.M. Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts. Journal of Neuroscience 26 (2006) 1418-1428
    • (2006) Journal of Neuroscience , vol.26 , pp. 1418-1428
    • Woo, S.1    Gomez, T.M.2
  • 49
    • 34249825465 scopus 로고    scopus 로고
    • Fasudil, a Rho kinase (ROCK) inhibitor, protects against ischemic neuronal damage in vitro and in vivo by acting directly on neurons
    • Yamashita K., Kotani Y., Nakajima Y., Shimazawa M., Yoshimura S., Nakashima S., et al. Fasudil, a Rho kinase (ROCK) inhibitor, protects against ischemic neuronal damage in vitro and in vivo by acting directly on neurons. Brain Research 1154 (2007) 215-224
    • (2007) Brain Research , vol.1154 , pp. 215-224
    • Yamashita, K.1    Kotani, Y.2    Nakajima, Y.3    Shimazawa, M.4    Yoshimura, S.5    Nakashima, S.6


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