메뉴 건너뛰기




Volumn 14, Issue 13, 2013, Pages 1565-1578

Pomegranate use to attenuate bone loss in major musculoskeletal diseases: An evidence-based review

Author keywords

Osteoarthritis; Osteoporosis; Pomegranate; Rheumatoid arthritis

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; POMEGRANATE EXTRACT; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; BONE DENSITY CONSERVATION AGENT; PLANT EXTRACT;

EID: 84889028717     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/1389450114666131108155039     Document Type: Review
Times cited : (16)

References (92)
  • 1
    • 85034658993 scopus 로고    scopus 로고
    • WHO Scientific Group on the Assessment of Osteoporosis at Primary Health Care Level
    • World Health Organization, Brussels, Belgium, WHO Press, Geneva 5-7 May 2004
    • World Health Organization, 2007: WHO Scientific Group on the Assessment of Osteoporosis at Primary Health Care Level. Summary Meeting Report. Brussels, Belgium, WHO Press, Geneva 5-7 May 2004.
    • (2007) Summary Meeting Report
  • 2
    • 78651381678 scopus 로고    scopus 로고
    • Facts and statistics about osteoporosis and its impact. International Osteoporosis Foundation
    • International Osteoporosis Foundation
    • International Osteoporosis Foundation: Facts and statistics about osteoporosis and its impact. International Osteoporosis Foundation. Journal of Bone and Mineral Research 2009 4:113-118, http://www.iofbonehealth.org/facts-andstatistics.html
    • (2009) Journal of Bone and Mineral Research , vol.4 , pp. 113-118
  • 3
    • 0033775218 scopus 로고    scopus 로고
    • Osteoarthritis: New insights. Part 1: The disease and its risk factors
    • Felson DT, Lawrence RC, Dieppe PA, et al. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 2000; 133(8): 635-46.
    • (2000) Ann Intern Med , vol.133 , Issue.8 , pp. 635-646
    • Felson, D.T.1    Lawrence, R.C.2    Dieppe, P.A.3
  • 4
    • 77951817331 scopus 로고    scopus 로고
    • Clinical predictors of elective total joint replacement in persons with end-stage knee osteoarthritis
    • Zeni JA, Axe MJ, Snyder-Mackler L. Clinical predictors of elective total joint replacement in persons with end-stage knee osteoarthritis. BMC Musculoskelet Disord 2010; 11: 86
    • (2010) BMC Musculoskelet Disord , vol.11 , pp. 86
    • Zeni, J.A.1    Axe, M.J.2    Snyder-Mackler, L.3
  • 5
    • 0029132296 scopus 로고
    • Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization
    • Oliveria SA, Felson DT, Reed JI, Cirillo PA, Walker AM. Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization. Arthritis Rheum 1995; 38(8): 1134-41
    • (1995) Arthritis Rheum , vol.38 , Issue.8 , pp. 1134-1141
    • Oliveria, S.A.1    Felson, D.T.2    Reed, J.I.3    Cirillo, P.A.4    Walker, A.M.5
  • 6
    • 55049138091 scopus 로고    scopus 로고
    • Lifetime risk of symptomatic knee osteoarthritis
    • Murphy L, Schwartz TA, Helmick CG, et al. Lifetime risk of symptomatic knee osteoarthritis. Arthritis Rheum 2008; 59(9): 1207-13.
    • (2008) Arthritis Rheum , vol.59 , Issue.9 , pp. 1207-1213
    • Murphy, L.1    Schwartz, T.A.2    Helmick, C.G.3
  • 7
    • 33745165234 scopus 로고    scopus 로고
    • National Hospital Discharge Survey
    • DeFrances C, Podgornik MN, 2004 National Hospital Discharge Survey. Adv Data 2006; 371: 1-19.
    • (2004) Adv Data , vol.371 , pp. 1-19
    • Defrances, C.1    Podgornik, M.N.2
  • 8
    • 0024473866 scopus 로고
    • Physical and histomorphological characteristics of iliac crest bone differ according to the grade of osteoarthritis at the hand
    • Gevers G, Dequeker J, Geusens P, Nyssen-Behets C, Dhem A. Physical and histomorphological characteristics of iliac crest bone differ according to the grade of osteoarthritis at the hand. Bone 1989; 10: 173-7
    • (1989) Bone , vol.10 , pp. 173-177
    • Gevers, G.1    Dequeker, J.2    Geusens, P.3    Nyssen-Behets, C.4    Dhem, A.5
  • 9
    • 0026059490 scopus 로고
    • Progression of osteoarthritis of the hand and metacarpal bone loss. A twenty-year follow-up of incident cases
    • Sowers M, Zobel D, Weissfeld L, Hawthorne VM, Carman W. Progression of osteoarthritis of the hand and metacarpal bone loss. A twenty-year follow-up of incident cases. Arthritis Rheum 1991; 34: 36-42.
    • (1991) Arthritis Rheum , vol.34 , pp. 36-42
    • Sowers, M.1    Zobel, D.2    Weissfeld, L.3    Hawthorne, V.M.4    Carman, W.5
  • 10
    • 0024460791 scopus 로고
    • Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases
    • Seibel MJ, Duncan A, Robins SP. Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases. J Rheumatol 1989; 16: 964-70.
    • (1989) J Rheumatol , vol.16 , pp. 964-970
    • Seibel, M.J.1    Duncan, A.2    Robins, S.P.3
  • 11
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 Revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 Revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24
    • (1988) Arthritis Rheum , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3
  • 12
    • 33645345411 scopus 로고    scopus 로고
    • Anti-CCP antibodies measured at disease onset help identify seronegative rheumatoid arthritis and predict radiological and functional outcome
    • Quinn MA, Gough AK, Green MJ, et al. Anti-CCP antibodies measured at disease onset help identify seronegative rheumatoid arthritis and predict radiological and functional outcome. Rheum (Oxford) 2006; 45: 478-80.
    • (2006) Rheum (Oxford) , vol.45 , pp. 478-480
    • Quinn, M.A.1    Gough, A.K.2    Green, M.J.3
  • 13
    • 85056037919 scopus 로고    scopus 로고
    • The Future of Rheumatoid Arthritis and Hand Surgery Combining Evolutionary Pharmacology and Surgical Technique
    • Malahias M, Gardner H, Hindocha S, Juma A, Khan W. The Future of Rheumatoid Arthritis and Hand Surgery Combining Evolutionary Pharmacology and Surgical Technique. Open Orthop J 2012; 6: 88-94.
    • (2012) Open Orthop J , vol.6 , pp. 88-94
    • Malahias, M.1    Gardner, H.2    Hindocha, S.3    Juma, A.4    Khan, W.5
  • 14
    • 0007284786 scopus 로고
    • Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films
    • Larsen A, Dale K, Eek. Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films. Acta Radiol Diagnosis 1975; 16: 393
    • (1975) Acta Radiol Diagnosis , vol.16 , pp. 393
    • Larsen, A.1    Dale, K.2    Eek3
  • 15
    • 0042838281 scopus 로고    scopus 로고
    • Inflammatory mediators as essential elements in bone remodeling
    • Goldring SR. Inflammatory mediators as essential elements in bone remodeling. Calcif Tissue Int 2003; 73(2): 97-100.
    • (2003) Calcif Tissue Int , vol.73 , Issue.2 , pp. 97-100
    • Goldring, S.R.1
  • 16
    • 38849194841 scopus 로고    scopus 로고
    • Osteoporosis in the patients with rheumatoid arthritis: The efficacy and the selection of the osteoporosis therapeutic drug
    • Nakayama H. Osteoporosis in the patients with rheumatoid arthritis: the efficacy and the selection of the osteoporosis therapeutic drug. Clin Calcium 2007; 17(10): 1607-12.
    • (2007) Clin Calcium , vol.17 , Issue.10 , pp. 1607-1612
    • Nakayama, H.1
  • 17
    • 84855582945 scopus 로고    scopus 로고
    • The Antiinflammatory Role of Vitamin E in Prevention of Osteoporosis
    • Shuid AN, Norazlina M, Norliza M, Ima Nirwana S. The Antiinflammatory Role of Vitamin E in Prevention of Osteoporosis. Adv Pharmacoll Sci 2012; 2012: 142702.
    • (2012) Adv Pharmacoll Sci , vol.2012 , Issue.14
    • Shuid, A.N.1    Norazlina, M.2    Norliza, M.3    Ima, N.S.4
  • 18
    • 0033841135 scopus 로고    scopus 로고
    • Advances in our understanding of the bone and joint pathology caused by Staphylococcus aureus infection
    • Nair SP, Williams RJ, Henderson B. Advances in our understanding of the bone and joint pathology caused by Staphylococcus aureus infection. Rheum(Oxford) 2000; 39(8): 821-34.
    • (2000) Rheum(Oxford) , vol.39 , Issue.8 , pp. 821-834
    • Nair, S.P.1    Williams, R.J.2    Henderson, B.3
  • 19
    • 0032694582 scopus 로고    scopus 로고
    • Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD
    • Srivastava S, Weitzmann MN, Cenci S, et al. Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD. J Clin Invest 1999; 104(4): 503-13.
    • (1999) J Clin Invest , vol.104 , Issue.4 , pp. 503-513
    • Srivastava, S.1    Weitzmann, M.N.2    Cenci, S.3
  • 20
    • 0031217666 scopus 로고    scopus 로고
    • Therapy with anti-TNF antibodies in patients with Crohn disease
    • Eigler A, Endres S. Therapy with anti-TNF antibodies in patients with Crohn disease. Z Gastroenterol 1997; 35(9): 899-901
    • (1997) Z Gastroenterol , vol.35 , Issue.9 , pp. 899-901
    • Eigler, A.1    Endres, S.2
  • 21
    • 0026546812 scopus 로고
    • Proinflammatory cytokines tumor necrosis factor-alpha and IL-6, but not IL-1, down-regulate the osteocalcin gene promoter
    • Li YP, Stashenko P. Proinflammatory cytokines tumor necrosis factor-alpha and IL-6, but not IL-1, down-regulate the osteocalcin gene promoter. J Immunol 1992; 148(3): 788-94.
    • (1992) J Immunol , vol.148 , Issue.3 , pp. 788-794
    • Li, Y.P.1    Stashenko, P.2
  • 22
    • 0026781667 scopus 로고
    • Effects of interleukin-1 beta and tumor necrosis factor-alpha on osteoblastic expression of osteocalcin and mineralized extracellular matrix in vitro
    • Taichman RS, Hauschka PV. Effects of interleukin-1 beta and tumor necrosis factor-alpha on osteoblastic expression of osteocalcin and mineralized extracellular matrix in vitro. Inflamm 1992; 16(6): 587-601
    • (1992) Inflamm , vol.16 , Issue.6 , pp. 587-601
    • Taichman, R.S.1    Hauschka, P.V.2
  • 23
    • 0030248272 scopus 로고    scopus 로고
    • Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts
    • Kitajima I, Soejima Y, Takasaki I, et al. Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts. Bone 1996; 19(3): 263-70.
    • (1996) Bone , vol.19 , Issue.3 , pp. 263-270
    • Kitajima, I.1    Soejima, Y.2    Takasaki, I.3
  • 24
    • 0031976864 scopus 로고    scopus 로고
    • Osteoblast programmed cell death (apoptosis): Modulation by growth factors and cytokines
    • Jilka RL, Weinstein RS, Bellido T, Parfitt AM, Manolagas SC. Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines. J Bone Miner Res 1998; 13(5): 793-802.
    • (1998) J Bone Miner Res , vol.13 , Issue.5 , pp. 793-802
    • Jilka, R.L.1    Weinstein, R.S.2    Bellido, T.3    Parfitt, A.M.4    Manolagas, S.C.5
  • 25
    • 0033695186 scopus 로고    scopus 로고
    • Inhibition of osteoblast differentiation by tumor necrosis factor-alpha
    • Gilbert L, He X, Farmer P, Boden S, et al. Inhibition of osteoblast differentiation by tumor necrosis factor-alpha. Endocrinology 2000; 141(11): 3956-64.
    • (2000) Endocrinology , vol.141 , Issue.11 , pp. 3956-3964
    • Gilbert, L.1    He, X.2    Farmer, P.3    Boden, S.4
  • 26
    • 33645226966 scopus 로고    scopus 로고
    • Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts
    • Kaneki H, Guo R, Chen D, et al. Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. J Biol Chem 2006; 281(7): 4326-33.
    • (2006) J Biol Chem , vol.281 , Issue.7 , pp. 4326-4333
    • Kaneki, H.1    Guo, R.2    Chen, D.3
  • 29
    • 0033788223 scopus 로고    scopus 로고
    • Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing
    • Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agr Food Chem 2000; 48: 4581-9.
    • (2000) J Agr Food Chem , vol.48 , pp. 4581-4589
    • Gil, M.I.1    Tomas-Barberan, F.A.2    Hess-Pierce, B.3    Holcroft, D.M.4    Kader, A.A.5
  • 30
    • 0034013311 scopus 로고    scopus 로고
    • Pomegranate juice consumption reduces oxidative stress, atherogenic apolipoprotein E-deficient mice
    • Aviram M, Dornfeld L, Rosenblat M, et al. Pomegranate juice consumption reduces oxidative stress, atherogenic apolipoprotein E-deficient mice. Am J Clin Nutr 2000; 71(5): 1062-76.
    • (2000) Am J Clin Nutr , vol.71 , Issue.5 , pp. 1062-1076
    • Aviram, M.1    Dornfeld, L.2    Rosenblat, M.3
  • 31
    • 0034907584 scopus 로고    scopus 로고
    • Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure
    • Aviram M, Dornfeld L. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis 2001; 158: 195-8.
    • (2001) Atherosclerosis , vol.158 , pp. 195-198
    • Aviram, M.1    Dornfeld, L.2
  • 32
    • 0034900739 scopus 로고    scopus 로고
    • Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular chlesterol accumulation and development of atherosclerosis
    • Kaplan M, Hayek T, Raz A, et al. Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular chlesterol accumulation and development of atherosclerosis. J Nutr 2001; 131: 2082-9.
    • (2001) J Nutr , vol.131 , pp. 2082-2089
    • Kaplan, M.1    Hayek, T.2    Raz, A.3
  • 33
    • 0036199315 scopus 로고    scopus 로고
    • A systematic screening of total antioxidants in dietary plants
    • Halvorsen BL, Holte K, Myhrstad MCW, et al. A systematic screening of total antioxidants in dietary plants. J Nutr 2002; 132: 461-71.
    • (2002) J Nutr , vol.132 , pp. 461-471
    • Halvorsen, B.L.1    Holte, K.2    Myhrstad, M.C.W.3
  • 34
    • 0036006635 scopus 로고    scopus 로고
    • Antioxidant activities of pomegranate fruit extract and its anthocyanidins: Delphinidin, cyaniding, and pelargonidin
    • Noda Y, Kaneyuki T, Mori A, Packe L. Antioxidant activities of pomegranate fruit extract and its anthocyanidins: Delphinidin, cyaniding, and pelargonidin. J Agr Food Chem 2002; 50: 166-71
    • (2002) J Agr Food Chem , vol.50 , pp. 166-171
    • Noda, Y.1    Kaneyuki, T.2    Mori, A.3    Packe, L.4
  • 35
    • 0036006626 scopus 로고    scopus 로고
    • Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extract using in vitro models
    • Singh RP, Murthy KNC, Jayaprakasha GK. Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extract using in vitro models. J Agr Food Chem 2002; 50: 81-6
    • (2002) J Agr Food Chem , vol.50 , pp. 81-86
    • Singh, R.P.1    Murthy, K.N.C.2    Jayaprakasha, G.K.3
  • 36
    • 47549111139 scopus 로고    scopus 로고
    • Therapeutic applications of pomegranate (Punica granatum L.): A review
    • Jurenka J. Therapeutic applications of pomegranate (Punica granatum L.): a review. Altern Med Rev 2008; 13: 128-44.
    • (2008) Altern Med Rev , vol.13 , pp. 128-144
    • Jurenka, J.1
  • 38
    • 0000232411 scopus 로고
    • Identification of estrone in pomegranate seeds
    • Heftmann E, Ko ST, Bennett RD. Identification of estrone in pomegranate seeds. Phytochem 1966; 5: 1337-9.
    • (1966) Phytochem , vol.5 , pp. 1337-1339
    • Heftmann, E.1    Ko, S.T.2    Bennett, R.D.3
  • 39
    • 0012369624 scopus 로고
    • The oestrogenic activity of pomegranate seed oil
    • Sharaf A, Nigm SAR. The oestrogenic activity of pomegranate seed oil. J Endocrinol 1964; 29: 91-2.
    • (1964) J Endocrinol , vol.29 , pp. 91-92
    • Sharaf, A.1    Nigm, S.A.R.2
  • 40
    • 33947223046 scopus 로고    scopus 로고
    • Effects of coumestrol on neonatal and adult mice osteoblasts activities
    • Sun JS, Li YY, Liu M, Sheu SY. Effects of coumestrol on neonatal and adult mice osteoblasts activities. J Biomed Mat Res 2007; 81: 214-23.
    • (2007) J Biomed Mat Res , vol.81 , pp. 214-223
    • Sun, J.S.1    Li, Y.Y.2    Liu, M.3    Sheu, S.Y.4
  • 41
    • 0035027736 scopus 로고    scopus 로고
    • Interaction of phytoestrogens with estrogen receptors alpha and beta
    • Morito K, Hirose T, Kinjo J, et al. Interaction of phytoestrogens with estrogen receptors alpha and beta. Biol Pharm Bull 2001; 24: 351-6
    • (2001) Biol Pharm Bull , vol.24 , pp. 351-356
    • Morito, K.1    Hirose, T.2    Kinjo, J.3
  • 42
    • 0042785118 scopus 로고    scopus 로고
    • Dietary phytoestrogens and their effect on bone: Evidence from in vitro and in vivo, human observational, and dietary intervention studies
    • Setchell KD, Lydeking-Olsen E. Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies. Am J Clin Nutr 2003; 78: 593-609
    • (2003) Am J Clin Nutr , vol.78 , pp. 593-609
    • Setchell, K.D.1    Lydeking-Olsen, E.2
  • 43
    • 38949165671 scopus 로고    scopus 로고
    • Influence of lifelong soy isoflavones consumption on bone mass in the rat
    • Mardon J, Mathey J, Kati-Coulibaly S, et al. Influence of lifelong soy isoflavones consumption on bone mass in the rat. Exp Biol Med 2008; 233: 229-37
    • (2008) Exp Biol Med , vol.233 , pp. 229-237
    • Mardon, J.1    Mathey, J.2    Kati-Coulibaly, S.3
  • 44
    • 1942487864 scopus 로고    scopus 로고
    • Pomegranate extract improves a depressive state and bone properties in menopausal syndrome model ovariectomized mice
    • Mori-Okamoto J, Otawara-Hamamoto Y, Yamato H, Yoshimora H. Pomegranate extract improves a depressive state and bone properties in menopausal syndrome model ovariectomized mice. J Ethnopharm 2004; 92: 93-101.
    • (2004) J Ethnopharm , vol.92 , pp. 93-101
    • Mori-Okamoto, J.1    Otawara-Hamamoto, Y.2    Yamato, H.3    Yoshimora, H.4
  • 45
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw J, Anderson G, Prentice R. Risks and benefits of estrogen plus progestin in postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. J Am Med Assoc 2002; 288: 321-33
    • (2002) J Am Med Assoc , vol.288 , pp. 321-333
    • Rossouw, J.1    Anderson, G.2    Prentice, R.3
  • 46
    • 0037830132 scopus 로고    scopus 로고
    • Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: The Women's Health Initiative randomized trial
    • Chlebowski RT, Hendrix SL, Langer RD, et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative randomized trial. J Am Med Assoc 2003; 289: 3243-53.
    • (2003) J Am Med Assoc , vol.289 , pp. 3243-3253
    • Chlebowski, R.T.1    Hendrix, S.L.2    Langer, R.D.3
  • 47
    • 0036201937 scopus 로고    scopus 로고
    • Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer
    • Kim ND, Mehta B, Yu W, et al. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Res Treat 2002; 71: 203-17
    • (2002) Breast Cancer Res Treat , vol.71 , pp. 203-217
    • Kim, N.D.1    Mehta, B.2    Yu, W.3
  • 48
    • 33845578167 scopus 로고    scopus 로고
    • Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis
    • de Nigris F, Williams-Ignarro S, Sica V, et al. Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis. Cardio Res 2007; 73: 414-23.
    • (2007) Cardio Res , vol.73 , pp. 414-423
    • de Nigris, F.1    Williams-Ignarro, S.2    Sica, V.3
  • 49
    • 33750496423 scopus 로고    scopus 로고
    • Cholesterol-lowering effect of concentrated pomegranate juice consumption in type II diabetic patients with hyperlipidemia
    • Esmaillzadeh A, Tahbaz F, Gaieni I, Alavi-Majd H, Azadbakht L. Cholesterol-lowering effect of concentrated pomegranate juice consumption in type II diabetic patients with hyperlipidemia. Int J Vit Nutr Res 2006; 76: 147-51.
    • (2006) Int J Vit Nutr Res , vol.76 , pp. 147-151
    • Esmaillzadeh, A.1    Tahbaz, F.2    Gaieni, I.3    Alavi-Majd, H.4    Azadbakht, L.5
  • 50
    • 33745495836 scopus 로고    scopus 로고
    • Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages
    • Rosenblat M, Hayek T, Aviram M. Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages. Atherosclerosis 2006;187: 363-71.
    • (2006) Atherosclerosis , vol.187 , pp. 363-371
    • Rosenblat, M.1    Hayek, T.2    Aviram, M.3
  • 51
    • 20144381777 scopus 로고    scopus 로고
    • In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice
    • Seeram NP, Adams LS, Henning SM, et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 2005; 16: 360-7.
    • (2005) J Nutr Biochem , vol.16 , pp. 360-367
    • Seeram, N.P.1    Adams, L.S.2    Henning, S.M.3
  • 52
    • 11144335895 scopus 로고    scopus 로고
    • Anthocyaninand hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice
    • Afaq F, Saleem M, Krueger CG, Reed JD, Mukhtar H. Anthocyaninand hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice. Int J Cancer 2005; 113: 423-33.
    • (2005) Int J Cancer , vol.113 , pp. 423-433
    • Afaq, F.1    Saleem, M.2    Krueger, C.G.3    Reed, J.D.4    Mukhtar, H.5
  • 53
    • 24744432725 scopus 로고    scopus 로고
    • Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro
    • Ahmed S, Wang N, Hafeez BB, Cheruvu VK, Haqqi TM. Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro. J Nutr 2005; 135: 2096-102.
    • (2005) J Nutr , vol.135 , pp. 2096-2102
    • Ahmed, S.1    Wang, N.2    Hafeez, B.B.3    Cheruvu, V.K.4    Haqqi, T.M.5
  • 54
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NFB
    • Hayden MS, Ghosh S. Signaling to NFB. Genes Devt 2004; 18: 2195-24.
    • (2004) Genes Devt , vol.18 , pp. 2124-2195
    • Hayden, M.S.1    Ghosh, S.2
  • 55
    • 27744496768 scopus 로고    scopus 로고
    • The biology of p38 kinase: A central role in inflammation
    • Schieven GS. The biology of p38 kinase: a central role in inflammation. Curr Top Med Chem. 2005; 5: 921-8.
    • (2005) Curr Top Med Chem , vol.5 , pp. 921-928
    • Schieven, G.S.1
  • 56
    • 0037169482 scopus 로고    scopus 로고
    • Expression of the Osteoblast Differentiation Factor RUNX2 (Cbfa1/AML3/Pebp2 A) Is Inhibited by Tumor Necrosis Factor-
    • Gilbert L, He X, Farmer P, et al. Expression of the Osteoblast Differentiation Factor RUNX2 (Cbfa1/AML3/Pebp2 A) Is Inhibited by Tumor Necrosis Factor-. J Biol Chem 2002; 277: 2695-701
    • (2002) J Biol Chem , vol.277 , pp. 2695-2701
    • Gilbert, L.1    He, X.2    Farmer, P.3
  • 57
    • 0141528518 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type 1 receptor
    • Abbas S, Zhang Y H, Clohisy J C, Abu-Amer Y. Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type 1 receptor. Cytokine 2003; 22: 33-41
    • (2003) Cytokine , vol.22 , pp. 33-41
    • Abbas, S.1    Zhang, Y.H.2    Clohisy, J.C.3    Abu-Amer, Y.4
  • 58
    • 17444389237 scopus 로고    scopus 로고
    • The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis
    • Gilbert LC, Rubin J, Nanes MS. The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis. Am J Physiol 2005; 288: E1011-E1018
    • (2005) Am J Physiol , vol.288
    • Gilbert, L.C.1    Rubin, J.2    Nanes, M.S.3
  • 59
    • 44749083500 scopus 로고    scopus 로고
    • Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis
    • Shukla M, Gupta K, Rasheed Z, Khan KA, Haqqi TM. Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. Nutr 2008; 24: 733-43.
    • (2008) Nutr , vol.24 , pp. 733-743
    • Shukla, M.1    Gupta, K.2    Rasheed, Z.3    Khan, K.A.4    Haqqi, T.M.5
  • 60
    • 75849116781 scopus 로고    scopus 로고
    • Chondroprotective effects of pomegranate juice on monoiodoacetate-induced osteoarthritis of the knee joint of mice
    • Hadipour-Jahromy M, Mozaffari-Kermani R. Chondroprotective effects of pomegranate juice on monoiodoacetate-induced osteoarthritis of the knee joint of mice. Phytother Res 2010; 24: 182-5.
    • (2010) Phytother Res , vol.24 , pp. 182-185
    • Hadipour-Jahromy, M.1    Mozaffari-Kermani, R.2
  • 61
    • 65649111637 scopus 로고    scopus 로고
    • Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract
    • Kim YH, Choi EM. Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract. Phytother Res 2009; 23(5): 737-9
    • (2009) Phytother Res , vol.23 , Issue.5 , pp. 737-739
    • Kim, Y.H.1    Choi, E.M.2
  • 62
    • 84856759442 scopus 로고    scopus 로고
    • Effects of pomegranate extracts on cartilage, bone and mesenchymal cells of mouse fetuses
    • Monsefi M, Parvin F, Talaei-Khozani T. Effects of pomegranate extracts on cartilage, bone and mesenchymal cells of mouse fetuses. Brit J Nutr 2012; 107(5): 683-90
    • (2012) Brit J Nutr , vol.107 , Issue.5 , pp. 683-690
    • Monsefi, M.1    Parvin, F.2    Talaei-Khozani, T.3
  • 63
    • 77957890472 scopus 로고    scopus 로고
    • Pomegranate extract inhibits the interleukin-1-induced activation of MKK-3, p38-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes
    • Rasheed Z, Akhtar N, Haqqi TM. Pomegranate extract inhibits the interleukin-1-induced activation of MKK-3, p38-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes. Arthritis Ther 2010; 12R: 195
    • (2010) Arthritis Ther , vol.12 R , pp. 195
    • Rasheed, Z.1    Akhtar, N.2    Haqqi, T.M.3
  • 64
    • 80052516984 scopus 로고    scopus 로고
    • Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: A pilot study
    • Balbir-Gurman A, Fuhrman B, Braun-Moscovici Y, Markovits D, Aviram M. Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: a pilot study. Israel Med Assoc J 2011; 13(8): 474-9
    • (2011) Israel Med Assoc J , vol.13 , Issue.8 , pp. 474-479
    • Balbir-Gurman, A.1    Fuhrman, B.2    Braun-Moscovici, Y.3    Markovits, D.4    Aviram, M.5
  • 66
    • 0038360770 scopus 로고    scopus 로고
    • Marked decrease in plasma antioxidants in aged osteoporotic women: Results of a crosssectional study
    • Maggio D, Barabani M, Pierandrei M, et al. Marked decrease in plasma antioxidants in aged osteoporotic women: results of a crosssectional study. J Clin Endocrinol Metab 2003; 88: 1523-7.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1523-1527
    • Maggio, D.1    Barabani, M.2    Pierandrei, M.3
  • 67
    • 0036184271 scopus 로고    scopus 로고
    • A duality in the roles of reactive oxygen species with respect to bone metabolism
    • Sontakke AN, Tare RS. A duality in the roles of reactive oxygen species with respect to bone metabolism. Clin Chim Acta 2002; 318: 145-8.
    • (2002) Clin Chim Acta , vol.318 , pp. 145-148
    • Sontakke, A.N.1    Tare, R.S.2
  • 68
    • 78651380656 scopus 로고    scopus 로고
    • The effects of Labisia Pumila var alata on bone markers and bone calcium in a rat model of post-menopausal osteoporosis
    • Shuid AN, Ping LL, Muhammad N, Mohamed N, Soelaiman IN. The effects of Labisia Pumila var alata on bone markers and bone calcium in a rat model of post-menopausal osteoporosis. J Ethnopharm 2011;133: 538-42
    • (2011) J Ethnopharm , vol.133 , pp. 538-542
    • Shuid, A.N.1    Ping, L.L.2    Muhammad, N.3    Mohamed, N.4    Soelaiman, I.N.5
  • 69
    • 79960813825 scopus 로고    scopus 로고
    • Piper sarmentosum enhances fracture healing in ovariectomised osteoporotic rats: Radiological study
    • Estai MA, Suhaimi FH, Das S, et al. Piper sarmentosum enhances fracture healing in ovariectomised osteoporotic rats: radiological study. Clinics 2011; 66(5): 865-72
    • (2011) Clinics , vol.66 , Issue.5 , pp. 865-872
    • Estai, M.A.1    Suhaimi, F.H.2    Das, S.3
  • 70
    • 80051478847 scopus 로고    scopus 로고
    • The AntiOsteoporotic Effect of Eurycoma Longifolia in Aged Orchidectomised Rat Model
    • Shuid AN, Abu Bakar MF, Abdul Shukor TA, et al. The AntiOsteoporotic Effect of Eurycoma Longifolia in Aged Orchidectomised Rat Model. Aging Male 2011; 14(3): 150-4
    • (2011) Aging Male , vol.14 , Issue.3 , pp. 150-154
    • Shuid, A.N.1    Abu, B.M.F.2    Abdul, S.T.A.3
  • 71
    • 84855959739 scopus 로고    scopus 로고
    • Comparison of the Effects of Tocotrienol and Estrogen on the Bone Markers and Dynamic Changes in Postmenopausal Osteoporosis Rat Model
    • Aktifanus AT, Shuid AN, Rashid NHA, et al. Comparison of the Effects of Tocotrienol and Estrogen on the Bone Markers and Dynamic Changes in Postmenopausal Osteoporosis Rat Model. Asian J Anim Vet Adv 2012: 7: 225-34
    • (2012) Asian J Anim Vet Adv , vol.7 , pp. 225-234
    • Aktifanus, A.T.1    Shuid, A.N.2    Rashid, N.H.A.3
  • 72
    • 34648821253 scopus 로고    scopus 로고
    • Recycled Palm Oil Is Better Than Soy Oil in Maintaining Bone Properties in Menopausal Syndrome Model of Ovariectomized Rat
    • Shuid AN, Loh H., Mohamed N, et al. Recycled Palm Oil Is Better Than Soy Oil in Maintaining Bone Properties in Menopausal Syndrome Model of Ovariectomized Rat. Asia Pac J Clin Nut 2007; 16(3): 393-402.
    • (2007) Asia Pac J Clin Nut , vol.16 , Issue.3 , pp. 393-402
    • Shuid, A.N.1    Loh, H.2    Mohamed, N.3
  • 73
    • 84855582945 scopus 로고    scopus 로고
    • The Antiinflammatory Role of Vitamin E in Prevention of Osteoporosis
    • Shuid AN, Mohamed N, Muhammad N, Soelaiman IN. The Antiinflammatory Role of Vitamin E in Prevention of Osteoporosis. Adv Pharmacol Sci 2012; 2012: 142702.
    • (2012) Adv Pharmacol Sci , vol.2012 , pp. 142702
    • Shuid, A.N.1    Mohamed, N.2    Muhammad, N.3    Soelaiman, I.N.4
  • 74
    • 3042653405 scopus 로고    scopus 로고
    • Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intimamedia thickness, blood pressure and LDL oxidation
    • Aviram M, Rosenblat M, Gaitini D, et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intimamedia thickness, blood pressure and LDL oxidation. Clin Nutr 2004; 23: 423-33.
    • (2004) Clin Nutr , vol.23 , pp. 423-433
    • Aviram, M.1    Rosenblat, M.2    Gaitini, D.3
  • 75
    • 33645452706 scopus 로고    scopus 로고
    • Pomegranate byproduct administration to apolipoprotein e-deficient mice attenuates atherosclerosis development as a result of decreased macrophage oxidative stress and reduced cellular uptake of oxidized lowdensity lipoprotein
    • Rosenblat M, Volkova N, Coleman R, Aviram M. Pomegranate byproduct administration to apolipoprotein e-deficient mice attenuates atherosclerosis development as a result of decreased macrophage oxidative stress and reduced cellular uptake of oxidized lowdensity lipoprotein. J Agr Food Chem 2006; 54: 1928-35.
    • (2006) J Agr Food Chem , vol.54 , pp. 1928-1935
    • Rosenblat, M.1    Volkova, N.2    Coleman, R.3    Aviram, M.4
  • 76
    • 80051855181 scopus 로고    scopus 로고
    • Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: Studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins
    • Aviram M, Volkova N, Coleman R, et al. Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins. J Agr Food Chem 2008; 56: 1148-56
    • (2008) J Agr Food Chem , vol.56 , pp. 1148-1156
    • Aviram, M.1    Volkova, N.2    Coleman, R.3
  • 77
    • 29144435210 scopus 로고    scopus 로고
    • Molecular Targets of Dietary Polyphenols with Anti-inflammatory Properties
    • Yoon JH, Baek SJ. Molecular Targets of Dietary Polyphenols with Anti-inflammatory Properties. Yonsei Med J 2005; 46(5): 585-96
    • (2005) Yonsei Med J , vol.46 , Issue.5 , pp. 585-596
    • Yoon, J.H.1    Baek, S.J.2
  • 78
    • 0025184711 scopus 로고
    • The role of interleukin-1 in postmenopausal bone loss
    • Pacifici R, Rifas L, McCracken R, Avioli LV. The role of interleukin-1 in postmenopausal bone loss. Exp Gerontol 1990; 25(3-4): 309-16.
    • (1990) Exp Gerontol , vol.25 , Issue.3-4 , pp. 309-316
    • Pacifici, R.1    Rifas, L.2    McCracken, R.3    Avioli, L.V.4
  • 80
    • 33847282407 scopus 로고    scopus 로고
    • Negative effects of nicotine on bone resorbing cytokines and bone histomorphometric parameters in male rats
    • Hermizi H, Faizah O, Ima-Nirwana S, Shuid AN, Luke DA, Norazlina M. Negative effects of nicotine on bone resorbing cytokines and bone histomorphometric parameters in male rats. Jour Bone Min Metab 2007; 25: 93-98
    • (2007) Jour Bone Min Metab , vol.25 , pp. 93-98
    • Hermizi, H.1    Faizah, O.2    Ima-Nirwana, S.3    Shuid, A.N.4    Luke, D.A.5    Norazlina, M.6
  • 81
    • 0030927622 scopus 로고    scopus 로고
    • Missense mutation abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia
    • Lee B, Thirunavukkarasu K, Zhou L, et al. Missense mutation abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nat Genet 1997; 16: 307-10.
    • (1997) Nat Genet , vol.16 , pp. 307-310
    • Lee, B.1    Thirunavukkarasu, K.2    Zhou, L.3
  • 82
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblast
    • Komori T, Yagi H, Nomura S, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblast. Cell 1997; 89: 755-64.
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3
  • 83
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto F, Thornell AP, Crompton T, et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 1997; 89: 765-71
    • (1997) Cell , vol.89 , pp. 765-771
    • Otto, F.1    Thornell, A.P.2    Crompton, T.3
  • 84
    • 0035462786 scopus 로고    scopus 로고
    • Suppressive effects of genistein dosage and resistance exercise on bone loss in ovariectomized rats
    • Nakajima D, Kim CS, Oh TW, et al. Suppressive effects of genistein dosage and resistance exercise on bone loss in ovariectomized rats. J Physiol Anthropol Appl Human Sci 2001; 20: 285-91.
    • (2001) J Physiol Anthropol Appl Human Sci , vol.20 , pp. 285-291
    • Nakajima, D.1    Kim, C.S.2    Oh, T.W.3
  • 85
    • 0034637023 scopus 로고    scopus 로고
    • Difference in effective dosage of genistein on bone and uterus in ovariectomized mice
    • Ishimi Y, Arai N, Wang X, et al. Difference in effective dosage of genistein on bone and uterus in ovariectomized mice. Biochem Biophys Res Commun 2000; 274: 697-701.
    • (2000) Biochem Biophys Res Commun , vol.274 , pp. 697-701
    • Ishimi, Y.1    Arai, N.2    Wang, X.3
  • 86
    • 0031934906 scopus 로고    scopus 로고
    • Preventive effects of the plant isoflavones, daidzin and genistin, on bone loss in ovariectomized rats fed a calcium-deficient diet
    • Ishida H, Uesugi T, Hirai K, et al. Preventive effects of the plant isoflavones, daidzin and genistin, on bone loss in ovariectomized rats fed a calcium-deficient diet. Biol Pharm Bull 1998; 21: 62-6.
    • (1998) Biol Pharm Bull , vol.21 , pp. 62-66
    • Ishida, H.1    Uesugi, T.2    Hirai, K.3
  • 87
    • 0033938138 scopus 로고    scopus 로고
    • Daidzein is more efficient than genistein in preventing ovariectomy-induced bone loss in rats
    • Picherit C, Coxam V, Bennetau-Pelissero C, et al. Daidzein is more efficient than genistein in preventing ovariectomy-induced bone loss in rats. J Nutr 2000; 130: 1675-81.
    • (2000) J Nutr , vol.130 , pp. 1675-1681
    • Picherit, C.1    Coxam, V.2    Bennetau-Pelissero, C.3
  • 88
    • 0033073312 scopus 로고    scopus 로고
    • Dietary soybeans intake and bone mineral density among 995 middle-aged women in Yokohama
    • Tsuchida K, Mizushima S, Toba M, Soda K. Dietary soybeans intake and bone mineral density among 995 middle-aged women in Yokohama. J Epidemiol 1999; 9: 14-9.
    • (1999) J Epidemiol , vol.9 , pp. 14-19
    • Tsuchida, K.1    Mizushima, S.2    Toba, M.3    Soda, K.4
  • 89
    • 0037199719 scopus 로고    scopus 로고
    • Efficacy of a soy rich diet in preventing postmenopausal osteoporosis: The Menfis randomized trial
    • Chiechi LM, Secreto G, D'Amore M, et al. Efficacy of a soy rich diet in preventing postmenopausal osteoporosis: The Menfis randomized trial. Maturitas 2002; 42: 295-300.
    • (2002) Maturitas , vol.42 , pp. 295-300
    • Chiechi, L.M.1    Secreto, G.2    D'Amore, M.3
  • 90
    • 0034855063 scopus 로고    scopus 로고
    • Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women
    • Scheiber MD, Liu JH, Subbiah MT, Rebar RW, Setchell KD. Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women. Menopause 2001; 8: 384-92.
    • (2001) Menopause , vol.8 , pp. 384-392
    • Scheiber, M.D.1    Liu, J.H.2    Subbiah, M.T.3    Rebar, R.W.4    Setchell, K.D.5
  • 91
    • 0034997713 scopus 로고    scopus 로고
    • Serum interleukin 6 is a major predictor of bone loss in women specific to the first decade past menopause
    • Scheidt-Nave C, Bismar H, Leidig-Bruckner G, et al. Serum interleukin 6 is a major predictor of bone loss in women specific to the first decade past menopause. J Clin Endocrinol Metab 2001; 86(5): 2032-42.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.5 , pp. 2032-2042
    • Scheidt-Nave, C.1    Bismar, H.2    Leidig-Bruckner, G.3
  • 92
    • 0035069304 scopus 로고    scopus 로고
    • Involvement of interleukin-6 and prostaglandin E2 in periarticular osteoporosis of postmenopausal women with rheumatoid arthritis
    • Sugiyama T. Involvement of interleukin-6 and prostaglandin E2 in periarticular osteoporosis of postmenopausal women with rheumatoid arthritis. J Bone Miner Metab 2001; 19: 89-96
    • (2001) J Bone Miner Metab , vol.19 , pp. 89-96
    • Sugiyama, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.