Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-κB pathways and inhibits skin tumorigenesis in CD-1 mice

International Journal of Cancer

Volumn 113, Issue 3, 2005, Pages 423-433

  Afaq, Farrukh ^a   Saleem, Mohammad ^a   Krueger, Christian G ^a   Reed, Jess D ^a   Mukhtar, Hasan ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Chemoprevention; Mitogen activated protein kinase; NF B; Ornithine decarboxylase; Pomegranate fruit extract

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; ACETONE; ANTHOCYANIN; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; STRESS ACTIVATED PROTEIN KINASE; TANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INCIDENCE; CARCINOGENESIS; CONTROLLED STUDY; DRUG EFFECT; DRUG HYDROLYSIS; DRUG SCREENING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; HYPERPLASIA; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; POMEGRANATE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SKIN EDEMA; SKIN TUMOR; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADMINISTRATION, TOPICAL; ANIMALS; ANTHOCYANINS; CARCINOGENS; CYCLOOXYGENASE 2; EDEMA; EPIDERMIS; FEMALE; FRUIT; HYDROLYZABLE TANNINS; HYPERPLASIA; I-KAPPA B KINASE; ISOENZYMES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; ORNITHINE DECARBOXYLASE; PHOSPHORYLATION; PLANT EXTRACTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN-SERINE-THREONINE KINASES; PUNICACEAE; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TETRADECANOYLPHORBOL ACETATE;

EID: 11144335895     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20587     Document Type: Article

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