메뉴 건너뛰기




Volumn 89, Issue 1, 2013, Pages

Androgen receptor (AR) physiological roles in male and female reproductive systems: Lessons learned from AR-Knockout mice lacking AR in selective cells

Author keywords

Androgen receptor; Androgens; ARKO mice; Fertility; Male sexual function; Reproductive system; Sex differentiation; Spermatogenesis

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; CALCITONIN GENE RELATED PEPTIDE; CHORIONIC GONADOTROPIN; FOLLITROPIN; GONADOTROPIN; PLEIOTROPHIN; TESTOSTERONE;

EID: 84888998261     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.109132     Document Type: Review
Times cited : (118)

References (191)
  • 1
    • 37349118115 scopus 로고    scopus 로고
    • Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex
    • Heemers HV, Tindall DJ. Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr Rev 2007; 28:778-808.
    • (2007) Endocr Rev , vol.28 , pp. 778-808
    • Heemers, H.V.1    Tindall, D.J.2
  • 3
    • 0036793098 scopus 로고    scopus 로고
    • The roles of androgen receptors and androgenbinding proteins in nongenomic androgen actions
    • Heinlein CA, Chang C. The roles of androgen receptors and androgenbinding proteins in nongenomic androgen actions. Mol Endocrinol 2002; 16:2181-2187.
    • (2002) Mol Endocrinol , vol.16 , pp. 2181-2187
    • Heinlein, C.A.1    Chang, C.2
  • 4
    • 77954385518 scopus 로고    scopus 로고
    • Androgens and the male reproductive tract: an overview of classical roles and current perspectives
    • Patrao MT, Silva EJ, Avellar MC. Androgens and the male reproductive tract: an overview of classical roles and current perspectives. Arq Bras Endocrinol Metab 2009; 53:934-945.
    • (2009) Arq Bras Endocrinol Metab , vol.53 , pp. 934-945
    • Patrao, M.T.1    Silva, E.J.2    Avellar, M.C.3
  • 5
    • 0025743234 scopus 로고
    • Androgen receptor expression in developing male reproductive organs
    • Cooke PS, Young P, Cunha GR. Androgen receptor expression in developing male reproductive organs. Endocrinology 1991; 128: 2867-2873.
    • (1991) Endocrinology , vol.128 , pp. 2867-2873
    • Cooke, P.S.1    Young, P.2    Cunha, G.R.3
  • 6
  • 7
    • 0031122231 scopus 로고    scopus 로고
    • Differential regulation of aromatase and androgen receptor in granulosa cells
    • Tetsuka M, Hillier SG. Differential regulation of aromatase and androgen receptor in granulosa cells. J Steroid Biochem Mol Biol 1997; 61: 233-239.
    • (1997) J Steroid Biochem Mol Biol , vol.61 , pp. 233-239
    • Tetsuka, M.1    Hillier, S.G.2
  • 9
    • 77954828598 scopus 로고    scopus 로고
    • Granulosa cell-specific androgen receptors are critical regulators of ovarian development and function
    • Sen A, Hammes SR. Granulosa cell-specific androgen receptors are critical regulators of ovarian development and function. Mol Endocrinol 2010; 24:1393-1403.
    • (2010) Mol Endocrinol , vol.24 , pp. 1393-1403
    • Sen, A.1    Hammes, S.R.2
  • 10
    • 33847395764 scopus 로고    scopus 로고
    • Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice
    • Nagaosa K, Kishimoto A, Kizu R, Nakagawa A, Shiratsuchi A, Nakanishi Y. Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice. Reproduction 2007; 133:21-27.
    • (2007) Reproduction , vol.133 , pp. 21-27
    • Nagaosa, K.1    Kishimoto, A.2    Kizu, R.3    Nakagawa, A.4    Shiratsuchi, A.5    Nakanishi, Y.6
  • 11
    • 33646584544 scopus 로고    scopus 로고
    • Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis
    • Borch J, Metzdorff SB, Vinggaard AM, Brokken L, Dalgaard M. Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis. Toxicology 2006; 223:144-155.
    • (2006) Toxicology , vol.223 , pp. 144-155
    • Borch, J.1    Metzdorff, S.B.2    Vinggaard, A.M.3    Brokken, L.4    Dalgaard, M.5
  • 12
    • 0014955076 scopus 로고
    • X-linked gene for testicular feminization in the mouse
    • Lyon MF, Hawkes SG. X-linked gene for testicular feminization in the mouse. Nature 1970; 227:1217-1219.
    • (1970) Nature , vol.227 , pp. 1217-1219
    • Lyon, M.F.1    Hawkes, S.G.2
  • 14
    • 0018043199 scopus 로고
    • Endocrine regulation of reproductive development and function in the male
    • Desjardins C. Endocrine regulation of reproductive development and function in the male. J Anim Sci 1978; 47(suppl 2):56-79.
    • (1978) J Anim Sci , vol.47 , Issue.SUPPL. 2 , pp. 56-79
    • Desjardins, C.1
  • 15
    • 0029961628 scopus 로고    scopus 로고
    • Does testosterone diffuse down the wolffian duct during sexual differentiation?
    • Tong SY, Hutson JM, Watts LM. Does testosterone diffuse down the wolffian duct during sexual differentiation? J Urol 1996; 155:2057-2059.
    • (1996) J Urol , vol.155 , pp. 2057-2059
    • Tong, S.Y.1    Hutson, J.M.2    Watts, L.M.3
  • 16
    • 8244243948 scopus 로고    scopus 로고
    • Anatomical and functional aspects of testicular descent and cryptorchidism
    • Hutson JM, Hasthorpe S, Heyns CF. Anatomical and functional aspects of testicular descent and cryptorchidism. Endocr Rev 1997; 18:259-280.
    • (1997) Endocr Rev , vol.18 , pp. 259-280
    • Hutson, J.M.1    Hasthorpe, S.2    Heyns, C.F.3
  • 18
    • 0036327168 scopus 로고    scopus 로고
    • Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice
    • Lecureuil C, Fontaine I, Crepieux P, Guillou F. Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice. Genesis 2002; 33:114-118.
    • (2002) Genesis , vol.33 , pp. 114-118
    • Lecureuil, C.1    Fontaine, I.2    Crepieux, P.3    Guillou, F.4
  • 19
    • 0028130155 scopus 로고
    • Leydig cells: endocrine, paracrine, and autocrine regulation
    • Saez JM. Leydig cells: endocrine, paracrine, and autocrine regulation. Endocr Rev 1994; 15:574-626.
    • (1994) Endocr Rev , vol.15 , pp. 574-626
    • Saez, J.M.1
  • 20
    • 0034115882 scopus 로고    scopus 로고
    • Unique and multifunctional adhesion junctions in the testis: ectoplasmic specializations
    • Vogl AW, Pfeiffer DC, Mulholland D, Kimel G, Guttman J. Unique and multifunctional adhesion junctions in the testis: ectoplasmic specializations. Arch Histol Cytol 2000; 63:1-15.
    • (2000) Arch Histol Cytol , vol.63 , pp. 1-15
    • Vogl, A.W.1    Pfeiffer, D.C.2    Mulholland, D.3    Kimel, G.4    Guttman, J.5
  • 21
    • 0028102148 scopus 로고
    • Sertoli cells in testes containing or lacking germ cells: a comparative study of paracrine effects using the W (c-kit) gene mutant mouse model
    • De Franca LR, Bartke A, Borg KE, Cecim M, Fadden CT, Yagi A, Russell LD. Sertoli cells in testes containing or lacking germ cells: a comparative study of paracrine effects using the W (c-kit) gene mutant mouse model. Anat Rec 1994; 240:225-232.
    • (1994) Anat Rec , vol.240 , pp. 225-232
    • De Franca, L.R.1    Bartke, A.2    Borg, K.E.3    Cecim, M.4    Fadden, C.T.5    Yagi, A.6    Russell, L.D.7
  • 22
    • 3242879161 scopus 로고    scopus 로고
    • Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis
    • Mruk DD, Cheng CY. Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 2004; 25:747-806.
    • (2004) Endocr Rev , vol.25 , pp. 747-806
    • Mruk, D.D.1    Cheng, C.Y.2
  • 23
    • 0020120302 scopus 로고
    • Physiological significance of fluid secretion in the testis and blood-testis barrier
    • Waites GM, Gladwell RT. Physiological significance of fluid secretion in the testis and blood-testis barrier. Physiol Rev 1982; 62:624-671.
    • (1982) Physiol Rev , vol.62 , pp. 624-671
    • Waites, G.M.1    Gladwell, R.T.2
  • 24
    • 0024215975 scopus 로고
    • Protein secretions of Sertoli cells
    • Griswold MD. Protein secretions of Sertoli cells. Int Rev Cytol 1988; 110:133-156.
    • (1988) Int Rev Cytol , vol.110 , pp. 133-156
    • Griswold, M.D.1
  • 25
    • 0027771127 scopus 로고
    • The Sertoli-germ cell communication network in mammals
    • Jegou B. The Sertoli-germ cell communication network in mammals. Int Rev Cytol 1993; 147:25-96.
    • (1993) Int Rev Cytol , vol.147 , pp. 25-96
    • Jegou, B.1
  • 26
    • 0024396445 scopus 로고
    • Regulation of Sertoli cell function and differentiation through the actions of a testicular paracrine factor PMod- S
    • Norton JN, Skinner MK. Regulation of Sertoli cell function and differentiation through the actions of a testicular paracrine factor PMod- S. Endocrinology 1989; 124:2711-2719.
    • (1989) Endocrinology , vol.124 , pp. 2711-2719
    • Norton, J.N.1    Skinner, M.K.2
  • 27
    • 0024357340 scopus 로고
    • Regulation of Sertoli cell differentiated function: testicular transferrin and androgen-binding protein expression
    • Skinner MK, Schlitz SM, Anthony CT. Regulation of Sertoli cell differentiated function: testicular transferrin and androgen-binding protein expression. Endocrinology 1989; 124:3015-3024.
    • (1989) Endocrinology , vol.124 , pp. 3015-3024
    • Skinner, M.K.1    Schlitz, S.M.2    Anthony, C.T.3
  • 30
    • 18844407557 scopus 로고    scopus 로고
    • The role of androgens in Sertoli cell proliferation and functional maturation: studies in mice with total or Sertoli cell-selective ablation of the androgen receptor
    • Tan KA, De Gendt K, Atanassova N, Walker M, Sharpe RM, Saunders PT, Denolet E, Verhoeven G. The role of androgens in Sertoli cell proliferation and functional maturation: studies in mice with total or Sertoli cell-selective ablation of the androgen receptor. Endocrinology 2005; 146:2674-2683.
    • (2005) Endocrinology , vol.146 , pp. 2674-2683
    • Tan, K.A.1    De Gendt, K.2    Atanassova, N.3    Walker, M.4    Sharpe, R.M.5    Saunders, P.T.6    Denolet, E.7    Verhoeven, G.8
  • 31
    • 29744441949 scopus 로고    scopus 로고
    • Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model
    • Notini AJ, Davey RA, McManus JF, Bate KL, Zajac JD. Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model. J Mol Endocrinol 2005; 35:547-555.
    • (2005) J Mol Endocrinol , vol.35 , pp. 547-555
    • Notini, A.J.1    Davey, R.A.2    McManus, J.F.3    Bate, K.L.4    Zajac, J.D.5
  • 32
    • 79751503955 scopus 로고    scopus 로고
    • Association of testicular p63 expression and spermatogenesis in androgen receptor knockout (ARKO) mice
    • Yu JJ, Jiang YC. Association of testicular p63 expression and spermatogenesis in androgen receptor knockout (ARKO) mice. Aging Male 2011; 14:72-75.
    • (2011) Aging Male , vol.14 , pp. 72-75
    • Yu, J.J.1    Jiang, Y.C.2
  • 33
    • 2342595087 scopus 로고    scopus 로고
    • Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells
    • Chang C, Chen YT, Yeh SD, Xu Q, Wang RS, Guillou F, Lardy H, Yeh S. Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells. Proc Natl Acad Sci U S A 2004; 101:6876-6881.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6876-6881
    • Chang, C.1    Chen, Y.T.2    Yeh, S.D.3    Xu, Q.4    Wang, R.S.5    Guillou, F.6    Lardy, H.7    Yeh, S.8
  • 34
    • 34948871606 scopus 로고    scopus 로고
    • Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells
    • Tsai MY, Yeh SD, Wang RS, Yeh S, Zhang C, Lin HY, Tzeng CR, Chang C. Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells. Proc Natl Acad Sci U S A 2006; 103:18975-18980.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 18975-18980
    • Tsai, M.Y.1    Yeh, S.D.2    Wang, R.S.3    Yeh, S.4    Zhang, C.5    Lin, H.Y.6    Tzeng, C.R.7    Chang, C.8
  • 39
    • 0345827710 scopus 로고    scopus 로고
    • Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse
    • Johnston H, Baker PJ, Abel M, Charlton HM, Jackson G, Fleming L, Kumar TR, O'Shaughnessy PJ. Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse. Endocrinology 2004; 145:318-329.
    • (2004) Endocrinology , vol.145 , pp. 318-329
    • Johnston, H.1    Baker, P.J.2    Abel, M.3    Charlton, H.M.4    Jackson, G.5    Fleming, L.6    Kumar, T.R.7    O'Shaughnessy, P.J.8
  • 40
    • 67349249354 scopus 로고    scopus 로고
    • Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice
    • O'Shaughnessy PJ, Morris ID, Huhtaniemi I, Baker PJ, Abel MH. Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice. Mol Cell Endocrinol 2009; 306:2-8.
    • (2009) Mol Cell Endocrinol , vol.306 , pp. 2-8
    • O'Shaughnessy, P.J.1    Morris, I.D.2    Huhtaniemi, I.3    Baker, P.J.4    Abel, M.H.5
  • 41
    • 0017578731 scopus 로고
    • Movement of spermatocytes from the basal to the adluminal compartment of the rat testis
    • Russell L. Movement of spermatocytes from the basal to the adluminal compartment of the rat testis. Am J Anat 1977; 148:313-328.
    • (1977) Am J Anat , vol.148 , pp. 313-328
    • Russell, L.1
  • 43
    • 4544233717 scopus 로고    scopus 로고
    • Intratesticular androgen levels, androgen receptor localization, and androgen receptor expression in adult rat Sertoli cells
    • Hill CM, Anway MD, Zirkin BR, Brown TR. Intratesticular androgen levels, androgen receptor localization, and androgen receptor expression in adult rat Sertoli cells. Biol Reprod 2004; 71:1348-1358.
    • (2004) Biol Reprod , vol.71 , pp. 1348-1358
    • Hill, C.M.1    Anway, M.D.2    Zirkin, B.R.3    Brown, T.R.4
  • 46
    • 65549093602 scopus 로고    scopus 로고
    • Androgen receptor in Sertoli cells is not required for testosterone-induced suppression of spermatogenesis, but contributes to Sertoli cell organization in Utp14bjsd mice
    • Wang G, Weng CC, Shao SH, Zhou W, de Gendt K, Braun RE, Verhoeven G, Meistrich ML. Androgen receptor in Sertoli cells is not required for testosterone-induced suppression of spermatogenesis, but contributes to Sertoli cell organization in Utp14bjsd mice. J Androl 2009; 30:338-348.
    • (2009) J Androl , vol.30 , pp. 338-348
    • Wang, G.1    Weng, C.C.2    Shao, S.H.3    Zhou, W.4    de Gendt, K.5    Braun, R.E.6    Verhoeven, G.7    Meistrich, M.L.8
  • 48
    • 84859723303 scopus 로고    scopus 로고
    • Testicular development in mice lacking receptors for follicle stimulating hormone and androgen
    • O'Shaughnessy PJ, Monteiro A, Abel M. Testicular development in mice lacking receptors for follicle stimulating hormone and androgen. PLoS ONE 2012; 7:e35136.
    • (2012) PLoS ONE , vol.7
    • O'Shaughnessy, P.J.1    Monteiro, A.2    Abel, M.3
  • 49
    • 78751698608 scopus 로고    scopus 로고
    • Gene expression alterations by conditional knockout of androgen receptor in adult Sertoli cells of Utp14bjsd/jsd (jsd) mice
    • Zhou W, Wang G, Small CL, Liu Z, Weng CC, Yang L, Griswold MD, Meistrich ML. Gene expression alterations by conditional knockout of androgen receptor in adult Sertoli cells of Utp14bjsd/jsd (jsd) mice. Biol Reprod 2011; 84:400-408.
    • (2011) Biol Reprod , vol.84 , pp. 400-408
    • Zhou, W.1    Wang, G.2    Small, C.L.3    Liu, Z.4    Weng, C.C.5    Yang, L.6    Griswold, M.D.7    Meistrich, M.L.8
  • 50
    • 0017655350 scopus 로고
    • Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism
    • Cattanach BM, Iddon CA, Charlton HM, Chiappa SA, Fink G. Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism. Nature 1977; 269:338-340.
    • (1977) Nature , vol.269 , pp. 338-340
    • Cattanach, B.M.1    Iddon, C.A.2    Charlton, H.M.3    Chiappa, S.A.4    Fink, G.5
  • 51
    • 0025320221 scopus 로고
    • Effect of LH injections on testicular steroidogenesis, cholesterol side-chain cleavage P450 mRNA content and Leydig cell morphology in hypogonadal mice
    • Scott IS, Charlton HM, Cox BS, Grocock CA, Sheffield JW, O'Shaughnessy PJ. Effect of LH injections on testicular steroidogenesis, cholesterol side-chain cleavage P450 mRNA content and Leydig cell morphology in hypogonadal mice. J Endocrinol 1990; 125:131-138.
    • (1990) J Endocrinol , vol.125 , pp. 131-138
    • Scott, I.S.1    Charlton, H.M.2    Cox, B.S.3    Grocock, C.A.4    Sheffield, J.W.5    O'Shaughnessy, P.J.6
  • 52
    • 75149163369 scopus 로고    scopus 로고
    • Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors
    • O'Shaughnessy PJ, Monteiro A, Verhoeven G, De Gendt K, Abel MH. Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors. Reproduction 2010; 139:177-184.
    • (2010) Reproduction , vol.139 , pp. 177-184
    • O'Shaughnessy, P.J.1    Monteiro, A.2    Verhoeven, G.3    De Gendt, K.4    Abel, M.H.5
  • 53
    • 77953164432 scopus 로고    scopus 로고
    • Direct action through the Sertoli cells is essential for androgen stimulation of spermatogenesis
    • O'Shaughnessy PJ, Verhoeven G, De Gendt K, Monteiro A, Abel MH. Direct action through the Sertoli cells is essential for androgen stimulation of spermatogenesis. Endocrinology 2010; 151:2343-2348.
    • (2010) Endocrinology , vol.151 , pp. 2343-2348
    • O'Shaughnessy, P.J.1    Verhoeven, G.2    De Gendt, K.3    Monteiro, A.4    Abel, M.H.5
  • 57
    • 0036842115 scopus 로고    scopus 로고
    • Requirement of Bmpr1a for Mullerian duct regression during male sexual development
    • Jamin SP, Arango NA, Mishina Y, Hanks MC, Behringer RR. Requirement of Bmpr1a for Mullerian duct regression during male sexual development. Nat Genet 2002; 32:408-410.
    • (2002) Nat Genet , vol.32 , pp. 408-410
    • Jamin, S.P.1    Arango, N.A.2    Mishina, Y.3    Hanks, M.C.4    Behringer, R.R.5
  • 58
    • 0036712830 scopus 로고    scopus 로고
    • Failure of normal adult Leydig cell development in androgen-receptor-deficient mice
    • O'Shaughnessy PJ, Johnston H, Willerton L, Baker PJ. Failure of normal adult Leydig cell development in androgen-receptor-deficient mice. J Cell Sci 2002; 115:3491-3496.
    • (2002) J Cell Sci , vol.115 , pp. 3491-3496
    • O'Shaughnessy, P.J.1    Johnston, H.2    Willerton, L.3    Baker, P.J.4
  • 61
    • 72749101744 scopus 로고    scopus 로고
    • Androgen action via testicular peritubular myoid cells is essential for male fertility
    • Welsh M, Saunders PT, Atanassova N, Sharpe RM, Smith LB. Androgen action via testicular peritubular myoid cells is essential for male fertility. FASEB J 2009; 23:4218-4230.
    • (2009) FASEB J , vol.23 , pp. 4218-4230
    • Welsh, M.1    Saunders, P.T.2    Atanassova, N.3    Sharpe, R.M.4    Smith, L.B.5
  • 62
    • 0037015212 scopus 로고    scopus 로고
    • Smooth muscle expression of Cre recombinase and eGFP in transgenic mice
    • Xin HB, Deng KY, Rishniw M, Ji G, Kotlikoff MI. Smooth muscle expression of Cre recombinase and eGFP in transgenic mice. Physiol Genomics 2002; 10:211-215.
    • (2002) Physiol Genomics , vol.10 , pp. 211-215
    • Xin, H.B.1    Deng, K.Y.2    Rishniw, M.3    Ji, G.4    Kotlikoff, M.I.5
  • 63
    • 33748542875 scopus 로고    scopus 로고
    • A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre
    • Frutkin AD, Shi H, Otsuka G, Leveen P, Karlsson S, Dichek DA. A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre. J Mol Cell Cardiol 2006; 41:724-731.
    • (2006) J Mol Cell Cardiol , vol.41 , pp. 724-731
    • Frutkin, A.D.1    Shi, H.2    Otsuka, G.3    Leveen, P.4    Karlsson, S.5    Dichek, D.A.6
  • 64
  • 65
    • 78149444074 scopus 로고    scopus 로고
    • Androgen action via testicular arteriole smooth muscle cells is important for Leydig cell function, vasomotion and testicular fluid dynamics
    • Welsh M, Sharpe RM, Moffat L, Atanassova N, Saunders PT, Kilter S, Bergh A, Smith LB. Androgen action via testicular arteriole smooth muscle cells is important for Leydig cell function, vasomotion and testicular fluid dynamics. PLoS ONE 2010; 5:e13632.
    • (2010) PLoS ONE , vol.5
    • Welsh, M.1    Sharpe, R.M.2    Moffat, L.3    Atanassova, N.4    Saunders, P.T.5    Kilter, S.6    Bergh, A.7    Smith, L.B.8
  • 66
    • 37349107873 scopus 로고    scopus 로고
    • Targeted rearrangement of floxed alleles in smooth muscle cells in vivo
    • Frutkin AD, Shi H, Otsuka G, Dichek DA. Targeted rearrangement of floxed alleles in smooth muscle cells in vivo. Circ Res 2007; 101: e124-e125.
    • (2007) Circ Res , vol.101
    • Frutkin, A.D.1    Shi, H.2    Otsuka, G.3    Dichek, D.A.4
  • 67
    • 77954619231 scopus 로고    scopus 로고
    • Deletion of androgen receptor in the smooth muscle of the seminal vesicles impairs secretory function and alters its responsiveness to exogenous testosterone and estradiol
    • Welsh M, Moffat L, Jack L, McNeilly A, Brownstein D, Saunders PT, Sharpe RM, Smith LB. Deletion of androgen receptor in the smooth muscle of the seminal vesicles impairs secretory function and alters its responsiveness to exogenous testosterone and estradiol. Endocrinology 2010; 151:3374-3385.
    • (2010) Endocrinology , vol.151 , pp. 3374-3385
    • Welsh, M.1    Moffat, L.2    Jack, L.3    McNeilly, A.4    Brownstein, D.5    Saunders, P.T.6    Sharpe, R.M.7    Smith, L.B.8
  • 69
    • 0027418018 scopus 로고
    • Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues
    • Kimura N, Mizokami A, Oonuma T, Sasano H, Nagura H. Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues. J Histochem Cytochem 1993; 41: 671-678.
    • (1993) J Histochem Cytochem , vol.41 , pp. 671-678
    • Kimura, N.1    Mizokami, A.2    Oonuma, T.3    Sasano, H.4    Nagura, H.5
  • 70
    • 0028214881 scopus 로고
    • Androgen receptor distribution in rat testis: new implications for androgen regulation of spermatogenesis
    • Vornberger W, Prins G, Musto NA, Suarez-Quian CA. Androgen receptor distribution in rat testis: new implications for androgen regulation of spermatogenesis. Endocrinology 1994; 134:2307-2316.
    • (1994) Endocrinology , vol.134 , pp. 2307-2316
    • Vornberger, W.1    Prins, G.2    Musto, N.A.3    Suarez-Quian, C.A.4
  • 71
    • 0029991553 scopus 로고    scopus 로고
    • Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development
    • Zhou X, Kudo A, Kawakami H, Hirano H. Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development. Anat Rec 1996; 245:509-518.
    • (1996) Anat Rec , vol.245 , pp. 509-518
    • Zhou, X.1    Kudo, A.2    Kawakami, H.3    Hirano, H.4
  • 72
    • 0016215794 scopus 로고
    • Progesterone and androgen receptors in non-flagellate germ cells of the rat testis
    • Galena HJ, Pillai AK, Terner C. Progesterone and androgen receptors in non-flagellate germ cells of the rat testis. J Endocrinol 1974; 63:223-237.
    • (1974) J Endocrinol , vol.63 , pp. 223-237
    • Galena, H.J.1    Pillai, A.K.2    Terner, C.3
  • 74
    • 0031695118 scopus 로고    scopus 로고
    • Cre expression in primary spermatocytes: a tool for genetic engineering of the germ line
    • Vidal F, Sage J, Cuzin F, Rassoulzadegan M. Cre expression in primary spermatocytes: a tool for genetic engineering of the germ line. Mol Reprod Dev 1998; 51:274-280.
    • (1998) Mol Reprod Dev , vol.51 , pp. 274-280
    • Vidal, F.1    Sage, J.2    Cuzin, F.3    Rassoulzadegan, M.4
  • 75
    • 0016767238 scopus 로고
    • Normal spermatozoa from androgen-resistant germ cells of chimeric mice and the role of androgen in spermatogenesis
    • Lyon MF, Glenister PH, Lamoreux ML. Normal spermatozoa from androgen-resistant germ cells of chimeric mice and the role of androgen in spermatogenesis. Nature 1975; 258:620-622.
    • (1975) Nature , vol.258 , pp. 620-622
    • Lyon, M.F.1    Glenister, P.H.2    Lamoreux, M.L.3
  • 76
    • 0035000459 scopus 로고    scopus 로고
    • Murine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation
    • Johnston DS, Russell LD, Friel PJ, Griswold MD. Murine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation. Endocrinology 2001; 142:2405-2408.
    • (2001) Endocrinology , vol.142 , pp. 2405-2408
    • Johnston, D.S.1    Russell, L.D.2    Friel, P.J.3    Griswold, M.D.4
  • 77
    • 0021933888 scopus 로고
    • A biphasic model for the hormonal control of testicular descent
    • Hutson JM. A biphasic model for the hormonal control of testicular descent. Lancet 1985; 326:419-421.
    • (1985) Lancet , vol.326 , pp. 419-421
    • Hutson, J.M.1
  • 78
    • 77958565063 scopus 로고    scopus 로고
    • What signals testis descent?
    • Tremblay JJ. What signals testis descent? Biol Reprod 2010; 83: 687-689.
    • (2010) Biol Reprod , vol.83 , pp. 687-689
    • Tremblay, J.J.1
  • 79
    • 49449083090 scopus 로고    scopus 로고
    • Role of hormones, genes, and environment in human cryptorchidism
    • Foresta C, Zuccarello D, Garolla A, Ferlin A. Role of hormones, genes, and environment in human cryptorchidism. Endocr Rev 2008; 29: 560-580.
    • (2008) Endocr Rev , vol.29 , pp. 560-580
    • Foresta, C.1    Zuccarello, D.2    Garolla, A.3    Ferlin, A.4
  • 80
    • 32544459133 scopus 로고    scopus 로고
    • A new role for androgen in testicular descent: permitting gubernacular cell proliferation in response to the neuropeptide, calcitonin gene-related peptide
    • Shenker NS, Huynh J, Farmer PJ, Hutson JM. A new role for androgen in testicular descent: permitting gubernacular cell proliferation in response to the neuropeptide, calcitonin gene-related peptide. J Pediatr Surg 2006; 41:407-412.
    • (2006) J Pediatr Surg , vol.41 , pp. 407-412
    • Shenker, N.S.1    Huynh, J.2    Farmer, P.J.3    Hutson, J.M.4
  • 82
    • 12344267771 scopus 로고    scopus 로고
    • Gubernacular fibroblasts express the androgen receptor during testis descent in cryptorchid rats treated with human chorionic gonadotrophin
    • Vigueras RM, Reyes G, Moreno-Mendoza N, Merchant-Larios H. Gubernacular fibroblasts express the androgen receptor during testis descent in cryptorchid rats treated with human chorionic gonadotrophin. Urol Res 2004; 32:386-390.
    • (2004) Urol Res , vol.32 , pp. 386-390
    • Vigueras, R.M.1    Reyes, G.2    Moreno-Mendoza, N.3    Merchant-Larios, H.4
  • 83
    • 0038162609 scopus 로고    scopus 로고
    • Androgen receptor and calcitonin gene-related peptide in neurons of the genitofemoral nerve during testicular descent induced with human chorionic gonadotropin
    • Vigueras RM, Moreno-Mendoza N, Reyes G, Merchant-Larios H. Androgen receptor and calcitonin gene-related peptide in neurons of the genitofemoral nerve during testicular descent induced with human chorionic gonadotropin. Arch Med Res 2003; 34:166-170.
    • (2003) Arch Med Res , vol.34 , pp. 166-170
    • Vigueras, R.M.1    Moreno-Mendoza, N.2    Reyes, G.3    Merchant-Larios, H.4
  • 84
    • 0028275210 scopus 로고
    • Prenatal androgen blockade with flutamide inhibits masculinization of the genitofemoral nerve and testicular descent
    • Goh DW, Middlesworth W, Farmer PJ, Hutson JM. Prenatal androgen blockade with flutamide inhibits masculinization of the genitofemoral nerve and testicular descent. J Pediatr Surg 1994; 29:836-838.
    • (1994) J Pediatr Surg , vol.29 , pp. 836-838
    • Goh, D.W.1    Middlesworth, W.2    Farmer, P.J.3    Hutson, J.M.4
  • 85
    • 84873046500 scopus 로고    scopus 로고
    • Neuronal androgen receptor regulates insulin sensitivity via suppression of hypothalamic NF-kappaB-mediated PTP1B expression
    • Yu IC, Lin HY, Liu NC, Sparks JD, Yeh S, Fang LY, Chen L, Chang C. Neuronal androgen receptor regulates insulin sensitivity via suppression of hypothalamic NF-kappaB-mediated PTP1B expression. Diabetes 2013; 62:411-423.
    • (2013) Diabetes , vol.62 , pp. 411-423
    • Yu, I.C.1    Lin, H.Y.2    Liu, N.C.3    Sparks, J.D.4    Yeh, S.5    Fang, L.Y.6    Chen, L.7    Chang, C.8
  • 86
    • 65549120393 scopus 로고    scopus 로고
    • Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses
    • Raskin K, de Gendt K, Duittoz A, Liere P, Verhoeven G, Tronche F, Mhaouty-Kodja S. Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses. J Neurosci 2009; 29:4461-4470.
    • (2009) J Neurosci , vol.29 , pp. 4461-4470
    • Raskin, K.1    de Gendt, K.2    Duittoz, A.3    Liere, P.4    Verhoeven, G.5    Tronche, F.6    Mhaouty-Kodja, S.7
  • 89
    • 21644437758 scopus 로고    scopus 로고
    • Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development
    • Kobayashi A, Kwan KM, Carroll TJ, McMahon AP, Mendelsohn CL, Behringer RR. Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development 2005; 132:2809-2823.
    • (2005) Development , vol.132 , pp. 2809-2823
    • Kobayashi, A.1    Kwan, K.M.2    Carroll, T.J.3    McMahon, A.P.4    Mendelsohn, C.L.5    Behringer, R.R.6
  • 90
    • 0027731948 scopus 로고
    • The gubernaculum in adult female, adult male and TFM male mice
    • Griffiths AL, Momose Y, Hutson JM. The gubernaculum in adult female, adult male and TFM male mice. Int J Androl 1993; 16:380-384.
    • (1993) Int J Androl , vol.16 , pp. 380-384
    • Griffiths, A.L.1    Momose, Y.2    Hutson, J.M.3
  • 91
    • 46349102085 scopus 로고    scopus 로고
    • Severe subfertility in mice with androgen receptor inactivation in sex accessory organs but not in testis
    • Simanainen U, McNamara K, Davey RA, Zajac JD, Handelsman DJ. Severe subfertility in mice with androgen receptor inactivation in sex accessory organs but not in testis. Endocrinology 2008; 149:3330-3338.
    • (2008) Endocrinology , vol.149 , pp. 3330-3338
    • Simanainen, U.1    McNamara, K.2    Davey, R.A.3    Zajac, J.D.4    Handelsman, D.J.5
  • 93
    • 0015365320 scopus 로고
    • Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization
    • Goldstein JL, Wilson JD. Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization. J Clin Invest 1972; 51:1647-1658.
    • (1972) J Clin Invest , vol.51 , pp. 1647-1658
    • Goldstein, J.L.1    Wilson, J.D.2
  • 94
    • 66449083083 scopus 로고    scopus 로고
    • New insights into the role of androgens in wolffian duct stabilization in male and female rodents
    • Welsh M, Sharpe RM, Walker M, Smith LB, Saunders PT. New insights into the role of androgens in wolffian duct stabilization in male and female rodents. Endocrinology 2009; 150:2472-2480.
    • (2009) Endocrinology , vol.150 , pp. 2472-2480
    • Welsh, M.1    Sharpe, R.M.2    Walker, M.3    Smith, L.B.4    Saunders, P.T.5
  • 96
    • 0346258124 scopus 로고    scopus 로고
    • Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development
    • Macatee TL, Hammond BP, Arenkiel BR, Francis L, Frank DU, Moon AM. Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development. Development 2003; 130:6361-6374.
    • (2003) Development , vol.130 , pp. 6361-6374
    • Macatee, T.L.1    Hammond, B.P.2    Arenkiel, B.R.3    Francis, L.4    Frank, D.U.5    Moon, A.M.6
  • 98
    • 79951664120 scopus 로고    scopus 로고
    • Targeted inactivation of the androgen receptor gene in murine proximal epididymis causes epithelial hypotrophy and obstructive azoospermia
    • Krutskikh A, De Gendt K, Sharp V, Verhoeven G, Poutanen M, Huhtaniemi I. Targeted inactivation of the androgen receptor gene in murine proximal epididymis causes epithelial hypotrophy and obstructive azoospermia. Endocrinology 2011; 152:689-696.
    • (2011) Endocrinology , vol.152 , pp. 689-696
    • Krutskikh, A.1    De Gendt, K.2    Sharp, V.3    Verhoeven, G.4    Poutanen, M.5    Huhtaniemi, I.6
  • 99
    • 79951609855 scopus 로고    scopus 로고
    • Androgen receptor expression in the caput epididymal epithelium is essential for development of the initial segment and epididymal spermatozoa transit
    • O'Hara L, Welsh M, Saunders PT, Smith LB. Androgen receptor expression in the caput epididymal epithelium is essential for development of the initial segment and epididymal spermatozoa transit. Endocrinology 2011; 152:718-729.
    • (2011) Endocrinology , vol.152 , pp. 718-729
    • O'Hara, L.1    Welsh, M.2    Saunders, P.T.3    Smith, L.B.4
  • 100
    • 0342732880 scopus 로고    scopus 로고
    • Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures
    • Hebert JM, McConnell SK. Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol 2000; 222:296-306.
    • (2000) Dev Biol , vol.222 , pp. 296-306
    • Hebert, J.M.1    McConnell, S.K.2
  • 102
    • 0018002388 scopus 로고
    • The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wildtype and androgen-insensitive (Tfm) mice
    • Cunha GR, Lung B. The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wildtype and androgen-insensitive (Tfm) mice. J Exp Zool 1978; 205: 181-193.
    • (1978) J Exp Zool , vol.205 , pp. 181-193
    • Cunha, G.R.1    Lung, B.2
  • 103
    • 0027195141 scopus 로고
    • Assessment of prostatic protein secretion in tissue recombinants made of urogenital sinus mesenchyme and urothelium from normal or androgen-insensitive mice
    • Donjacour AA, Cunha GR. Assessment of prostatic protein secretion in tissue recombinants made of urogenital sinus mesenchyme and urothelium from normal or androgen-insensitive mice. Endocrinology 1993; 132:2342-2350.
    • (1993) Endocrinology , vol.132 , pp. 2342-2350
    • Donjacour, A.A.1    Cunha, G.R.2
  • 104
    • 0025824204 scopus 로고
    • Inability of Tfm (testicular feminization) epithelial cells to express androgen-dependent seminal vesicle secretory proteins in chimeric tissue recombinants
    • Cunha GR, Young P. Inability of Tfm (testicular feminization) epithelial cells to express androgen-dependent seminal vesicle secretory proteins in chimeric tissue recombinants. Endocrinology 1991; 128:3293-3298.
    • (1991) Endocrinology , vol.128 , pp. 3293-3298
    • Cunha, G.R.1    Young, P.2
  • 105
    • 0031878583 scopus 로고    scopus 로고
    • Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model
    • Hayward SW, Haughney PC, Rosen MA, Greulich KM, Weier HU, Dahiya R, Cunha GR. Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model. Differentiation 1998; 63:131-140.
    • (1998) Differentiation , vol.63 , pp. 131-140
    • Hayward, S.W.1    Haughney, P.C.2    Rosen, M.A.3    Greulich, K.M.4    Weier, H.U.5    Dahiya, R.6    Cunha, G.R.7
  • 107
    • 0021182777 scopus 로고
    • Antagonistic effect of androgen on prostatic cell death
    • Isaacs JT. Antagonistic effect of androgen on prostatic cell death. Prostate 1984; 5:545-557.
    • (1984) Prostate , vol.5 , pp. 545-557
    • Isaacs, J.T.1
  • 108
    • 0022967876 scopus 로고
    • Morphological and histological study of castration-induced degeneration and androgen-induced regeneration in the mouse prostate
    • Sugimura Y, Cunha GR, Donjacour AA. Morphological and histological study of castration-induced degeneration and androgen-induced regeneration in the mouse prostate. Biol Reprod 1986; 34:973-983.
    • (1986) Biol Reprod , vol.34 , pp. 973-983
    • Sugimura, Y.1    Cunha, G.R.2    Donjacour, A.A.3
  • 109
    • 0023901348 scopus 로고
    • Activation of programmed cell death in the rat ventral prostate after castration
    • Kyprianou N, Isaacs JT. Activation of programmed cell death in the rat ventral prostate after castration. Endocrinology 1988; 122:552-562.
    • (1988) Endocrinology , vol.122 , pp. 552-562
    • Kyprianou, N.1    Isaacs, J.T.2
  • 110
    • 0037440475 scopus 로고    scopus 로고
    • Hormonal, cellular, and molecular control of prostatic development
    • Marker PC, Donjacour AA, Dahiya R, Cunha GR. Hormonal, cellular, and molecular control of prostatic development. Dev Biol 2003; 253: 165-174.
    • (2003) Dev Biol , vol.253 , pp. 165-174
    • Marker, P.C.1    Donjacour, A.A.2    Dahiya, R.3    Cunha, G.R.4
  • 111
    • 0035392953 scopus 로고    scopus 로고
    • Conversion from a paracrine to an autocrine mechanism of androgen-stimulated growth during malignant transformation of prostatic epithelial cells
    • Gao J, Arnold JT, Isaacs JT. Conversion from a paracrine to an autocrine mechanism of androgen-stimulated growth during malignant transformation of prostatic epithelial cells. Cancer Res 2001; 61:5038-5044.
    • (2001) Cancer Res , vol.61 , pp. 5038-5044
    • Gao, J.1    Arnold, J.T.2    Isaacs, J.T.3
  • 112
    • 78951486492 scopus 로고    scopus 로고
    • Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia
    • Orr B, Vanpoucke G, Grace OC, Smith L, Anderson RA, Riddick AC, Franco OE, Hayward SW, Thomson AA. Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia. Prostate 2011; 71:305-317.
    • (2011) Prostate , vol.71 , pp. 305-317
    • Orr, B.1    Vanpoucke, G.2    Grace, O.C.3    Smith, L.4    Anderson, R.A.5    Riddick, A.C.6    Franco, O.E.7    Hayward, S.W.8    Thomson, A.A.9
  • 113
    • 0026617965 scopus 로고
    • Role of stroma in oestrogen-induced epithelial proliferation
    • Cunha GR, Young P. Role of stroma in oestrogen-induced epithelial proliferation. Epithelial Cell Biol 1992; 1:18-31.
    • (1992) Epithelial Cell Biol , vol.1 , pp. 18-31
    • Cunha, G.R.1    Young, P.2
  • 114
    • 84856026139 scopus 로고    scopus 로고
    • Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts
    • Yu S, Yeh CR, Niu Y, Chang HC, Tsai YC, Moses HL, Shyr CR, Chang C, Yeh S. Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts. Prostate 2012; 72:437-449.
    • (2012) Prostate , vol.72 , pp. 437-449
    • Yu, S.1    Yeh, C.R.2    Niu, Y.3    Chang, H.C.4    Tsai, Y.C.5    Moses, H.L.6    Shyr, C.R.7    Chang, C.8    Yeh, S.9
  • 115
    • 79951527527 scopus 로고    scopus 로고
    • Altered prostate epithelial development and IGF-1 signal in mice lacking the androgen receptor in stromal smooth muscle cells
    • Yu S, Zhang C, Lin CC, Niu Y, Lai KP, Chang HC, Yeh SD, Chang C, Yeh S. Altered prostate epithelial development and IGF-1 signal in mice lacking the androgen receptor in stromal smooth muscle cells. Prostate 2011; 71:517-524.
    • (2011) Prostate , vol.71 , pp. 517-524
    • Yu, S.1    Zhang, C.2    Lin, C.C.3    Niu, Y.4    Lai, K.P.5    Chang, H.C.6    Yeh, S.D.7    Chang, C.8    Yeh, S.9
  • 116
    • 84855215970 scopus 로고    scopus 로고
    • Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor
    • Lai KP, Yamashita S, Vitkus S, Shyr CR, Yeh S, Chang C. Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Mol Endocrinol 2012; 26:52-66.
    • (2012) Mol Endocrinol , vol.26 , pp. 52-66
    • Lai, K.P.1    Yamashita, S.2    Vitkus, S.3    Shyr, C.R.4    Yeh, S.5    Chang, C.6
  • 117
  • 120
    • 79959922580 scopus 로고    scopus 로고
    • Increased CK5/CK8-positive intermediate cells with stromal smooth muscle cell atrophy in the mice lacking prostate epithelial androgen receptor
    • Niu Y, Wang J, Shang Z, Huang SP, Shyr CR, Yeh S, Chang C. Increased CK5/CK8-positive intermediate cells with stromal smooth muscle cell atrophy in the mice lacking prostate epithelial androgen receptor. PLoS ONE 2011; 6:e20202.
    • (2011) PLoS ONE , vol.6
    • Niu, Y.1    Wang, J.2    Shang, Z.3    Huang, S.P.4    Shyr, C.R.5    Yeh, S.6    Chang, C.7
  • 122
    • 66849128249 scopus 로고    scopus 로고
    • Androgen sensitivity of prostate epithelium is enhanced by postnatal androgen receptor inactivation
    • Simanainen U, McNamara K, Gao YR, Handelsman DJ. Androgen sensitivity of prostate epithelium is enhanced by postnatal androgen receptor inactivation. Am J Physiol Endocrinol Metab 2009; 296: E1335-E1343.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Simanainen, U.1    McNamara, K.2    Gao, Y.R.3    Handelsman, D.J.4
  • 123
    • 84862111854 scopus 로고    scopus 로고
    • Suppressor role of androgen receptor in proliferation of prostate basal epithelial and progenitor cells
    • Lee SO, Tian J, Huang CK, Ma Z, Lai KP, Hsiao H, Jiang M, Yeh S, Chang C. Suppressor role of androgen receptor in proliferation of prostate basal epithelial and progenitor cells. J Endocrinol 2012; 213: 173-182.
    • (2012) J Endocrinol , vol.213 , pp. 173-182
    • Lee, S.O.1    Tian, J.2    Huang, C.K.3    Ma, Z.4    Lai, K.P.5    Hsiao, H.6    Jiang, M.7    Yeh, S.8    Chang, C.9
  • 124
    • 0034913316 scopus 로고    scopus 로고
    • Androgen induces differentiation of a human papillomavirus 16 E6/E7 immortalized prostate epithelial cell line
    • Ling MT, Chan KW, Choo CK. Androgen induces differentiation of a human papillomavirus 16 E6/E7 immortalized prostate epithelial cell line. J Endocrinol 2001; 170:287-296.
    • (2001) J Endocrinol , vol.170 , pp. 287-296
    • Ling, M.T.1    Chan, K.W.2    Choo, C.K.3
  • 126
    • 0033819596 scopus 로고    scopus 로고
    • Localization of androgen and estrogen receptors in rat and primate tissues
    • Pelletier G. Localization of androgen and estrogen receptors in rat and primate tissues. Histol Histopathol 2000; 15:1261-1270.
    • (2000) Histol Histopathol , vol.15 , pp. 1261-1270
    • Pelletier, G.1
  • 127
    • 0021828752 scopus 로고
    • Identification and partial characterization of the cytoplasmic androgen receptor in bovine ovarian capsule
    • Ito A, Sato W, Mori Y. Identification and partial characterization of the cytoplasmic androgen receptor in bovine ovarian capsule. J Steroid Biochem 1985; 23:27-31.
    • (1985) J Steroid Biochem , vol.23 , pp. 27-31
    • Ito, A.1    Sato, W.2    Mori, Y.3
  • 128
    • 0026587410 scopus 로고
    • Immunohistochemical localization of androgen receptor in the human ovary throughout the menstrual cycle in relation to estrogen and progesterone receptor expression
    • Horie K, Takakura K, Fujiwara H, Suginami H, Liao S, Mori T. Immunohistochemical localization of androgen receptor in the human ovary throughout the menstrual cycle in relation to estrogen and progesterone receptor expression. Hum Reprod 1992; 7:184-190.
    • (1992) Hum Reprod , vol.7 , pp. 184-190
    • Horie, K.1    Takakura, K.2    Fujiwara, H.3    Suginami, H.4    Liao, S.5    Mori, T.6
  • 130
    • 0035150932 scopus 로고    scopus 로고
    • The expression of androgen receptor, cytochrome P450 aromatase and FSH receptor mRNA in the porcine ovary
    • Slomczynska M, Duda M, Slzak K. The expression of androgen receptor, cytochrome P450 aromatase and FSH receptor mRNA in the porcine ovary. Folia Histochem Cytobiol 2001; 39:9-13.
    • (2001) Folia Histochem Cytobiol , vol.39 , pp. 9-13
    • Slomczynska, M.1    Duda, M.2    Slzak, K.3
  • 131
    • 0035172099 scopus 로고    scopus 로고
    • Immunolocalization of androgen receptors in the canine ovary and their relation to sex steroid hormone concentrations
    • Vermeirsch H, Simoens P, Coryn M, Van den Broeck W. Immunolocalization of androgen receptors in the canine ovary and their relation to sex steroid hormone concentrations. Reproduction 2001; 122:711-721.
    • (2001) Reproduction , vol.122 , pp. 711-721
    • Vermeirsch, H.1    Simoens, P.2    Coryn, M.3    Van den Broeck, W.4
  • 132
    • 0642272532 scopus 로고    scopus 로고
    • Steroid receptors in the uterus: implications in endometriosis
    • Moutsatsou P, Sekeris CE. Steroid receptors in the uterus: implications in endometriosis. Ann N Y Acad Sci 2003; 997:209-222.
    • (2003) Ann N Y Acad Sci , vol.997 , pp. 209-222
    • Moutsatsou, P.1    Sekeris, C.E.2
  • 133
    • 0842303575 scopus 로고    scopus 로고
    • Localization and estrogenic regulation of androgen receptor mRNA expression in the mouse uterus and vagina
    • Pelletier G, Luu-The V, Li S, Labrie F. Localization and estrogenic regulation of androgen receptor mRNA expression in the mouse uterus and vagina. J Endocrinol 2004; 180:77-85.
    • (2004) J Endocrinol , vol.180 , pp. 77-85
    • Pelletier, G.1    Luu-The, V.2    Li, S.3    Labrie, F.4
  • 135
    • 0027067052 scopus 로고
    • Immunohistochemical localization of androgen receptor in the human endometrium, decidua, placenta and pathological conditions of the endometrium
    • Horie K, Takakura K, Imai K, Liao S, Mori T. Immunohistochemical localization of androgen receptor in the human endometrium, decidua, placenta and pathological conditions of the endometrium. Hum Reprod 1992; 7:1461-1466.
    • (1992) Hum Reprod , vol.7 , pp. 1461-1466
    • Horie, K.1    Takakura, K.2    Imai, K.3    Liao, S.4    Mori, T.5
  • 137
    • 0031047416 scopus 로고    scopus 로고
    • Location and developmental regulation of androgen receptor in primate ovary
    • Hillier SG, Tetsuka M, Fraser HM. Location and developmental regulation of androgen receptor in primate ovary. Hum Reprod 1997; 12:107-111.
    • (1997) Hum Reprod , vol.12 , pp. 107-111
    • Hillier, S.G.1    Tetsuka, M.2    Fraser, H.M.3
  • 138
    • 0031757965 scopus 로고    scopus 로고
    • Androgen receptor gene expression in the primate ovary: cellular localization, regulation, and functional correlations
    • Weil SJ, Vendola K, Zhou J, Adesanya OO, Wang J, Okafor J, Bondy CA. Androgen receptor gene expression in the primate ovary: cellular localization, regulation, and functional correlations. J Clin Endocrinol Metab 1998; 83:2479-2485.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2479-2485
    • Weil, S.J.1    Vendola, K.2    Zhou, J.3    Adesanya, O.O.4    Wang, J.5    Okafor, J.6    Bondy, C.A.7
  • 139
    • 0036211567 scopus 로고    scopus 로고
    • Androgen receptor and follicle-stimulating hormone receptor in the pig ovary during the follicular phase of the estrous cycle
    • Cardenas H, Pope WF. Androgen receptor and follicle-stimulating hormone receptor in the pig ovary during the follicular phase of the estrous cycle. Mol Reprod Dev 2002; 62:92-98.
    • (2002) Mol Reprod Dev , vol.62 , pp. 92-98
    • Cardenas, H.1    Pope, W.F.2
  • 140
    • 0032525901 scopus 로고    scopus 로고
    • Androgens stimulate early stages of follicular growth in the primate ovary
    • Vendola KA, Zhou J, Adesanya OO, Weil SJ, Bondy CA. Androgens stimulate early stages of follicular growth in the primate ovary. J Clin Invest 1998; 101:2622-2629.
    • (1998) J Clin Invest , vol.101 , pp. 2622-2629
    • Vendola, K.A.1    Zhou, J.2    Adesanya, O.O.3    Weil, S.J.4    Bondy, C.A.5
  • 141
    • 0028148968 scopus 로고
    • Androgen receptor expression in human ovarian and uterine tissue of long-term androgen-treated transsexual women
    • Chadha S, Pache TD, Huikeshoven JM, Brinkmann AO, van der Kwast TH. Androgen receptor expression in human ovarian and uterine tissue of long-term androgen-treated transsexual women. Hum Pathol 1994; 25: 1198-1204.
    • (1994) Hum Pathol , vol.25 , pp. 1198-1204
    • Chadha, S.1    Pache, T.D.2    Huikeshoven, J.M.3    Brinkmann, A.O.4    van der Kwast, T.H.5
  • 143
    • 0031877054 scopus 로고    scopus 로고
    • Effect of androgens on the development of mouse follicles growing in vitro
    • Murray AA, Gosden RG, Allison V, Spears N. Effect of androgens on the development of mouse follicles growing in vitro. J Reprod Fertil 1998; 113:27-33.
    • (1998) J Reprod Fertil , vol.113 , pp. 27-33
    • Murray, A.A.1    Gosden, R.G.2    Allison, V.3    Spears, N.4
  • 145
    • 0036221618 scopus 로고    scopus 로고
    • Increased ovulation rate in gilts treated with dihydrotestosterone
    • Cardenas H, Herrick JR, Pope WF. Increased ovulation rate in gilts treated with dihydrotestosterone. Reproduction 2002; 123:527-533.
    • (2002) Reproduction , vol.123 , pp. 527-533
    • Cardenas, H.1    Herrick, J.R.2    Pope, W.F.3
  • 146
    • 0021241022 scopus 로고
    • Site of action of androgens on folliclestimulating hormone-induced aromatase activity in cultured rat granulosa cells
    • Daniel SA, Armstrong DT. Site of action of androgens on folliclestimulating hormone-induced aromatase activity in cultured rat granulosa cells. Endocrinology 1984; 114:1975-1982.
    • (1984) Endocrinology , vol.114 , pp. 1975-1982
    • Daniel, S.A.1    Armstrong, D.T.2
  • 147
    • 0033308735 scopus 로고    scopus 로고
    • Androgen and folliclestimulating hormone interactions in primate ovarian follicle development
    • Weil S, Vendola K, Zhou J, Bondy CA. Androgen and folliclestimulating hormone interactions in primate ovarian follicle development. J Clin Endocrinol Metab 1999; 84:2951-2956.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2951-2956
    • Weil, S.1    Vendola, K.2    Zhou, J.3    Bondy, C.A.4
  • 148
    • 0032851538 scopus 로고    scopus 로고
    • Androgens promote insulin-like growth factor-I and insulin-like growth factor-I receptor gene expression in the primate ovary
    • Vendola K, Zhou J, Wang J, Bondy CA. Androgens promote insulin-like growth factor-I and insulin-like growth factor-I receptor gene expression in the primate ovary. Hum Reprod 1999; 14:2328-2332.
    • (1999) Hum Reprod , vol.14 , pp. 2328-2332
    • Vendola, K.1    Zhou, J.2    Wang, J.3    Bondy, C.A.4
  • 149
    • 0032764132 scopus 로고    scopus 로고
    • Androgens promote oocyte insulin-like growth factor I expression and initiation of follicle development in the primate ovary
    • Vendola K, Zhou J, Wang J, Famuyiwa OA, Bievre M, Bondy CA. Androgens promote oocyte insulin-like growth factor I expression and initiation of follicle development in the primate ovary. Biol Reprod 1999; 61:353-357.
    • (1999) Biol Reprod , vol.61 , pp. 353-357
    • Vendola, K.1    Zhou, J.2    Wang, J.3    Famuyiwa, O.A.4    Bievre, M.5    Bondy, C.A.6
  • 150
    • 3142696975 scopus 로고    scopus 로고
    • Interactions between androgen and growth factors in granulosa cell subtypes of porcine antral follicles
    • Hickey TE, Marrocco DL, Gilchrist RB, Norman RJ, Armstrong DT. Interactions between androgen and growth factors in granulosa cell subtypes of porcine antral follicles. Biol Reprod 2004; 71:45-52.
    • (2004) Biol Reprod , vol.71 , pp. 45-52
    • Hickey, T.E.1    Marrocco, D.L.2    Gilchrist, R.B.3    Norman, R.J.4    Armstrong, D.T.5
  • 151
    • 9244261908 scopus 로고    scopus 로고
    • Regulation of ovarian follicular development in primates: facts and hypotheses
    • Gougeon A. Regulation of ovarian follicular development in primates: facts and hypotheses. Endocr Rev 1996; 17:121-155.
    • (1996) Endocr Rev , vol.17 , pp. 121-155
    • Gougeon, A.1
  • 153
    • 0019306165 scopus 로고
    • Reduced reproductive performance in androgenresistant Tfm/Tfm female mice
    • Lyon MF, Glenister PH. Reduced reproductive performance in androgenresistant Tfm/Tfm female mice. Proc R Soc Lond B Biol Sci 1980; 208: 1-12.
    • (1980) Proc R Soc Lond B Biol Sci , vol.208 , pp. 1-12
    • Lyon, M.F.1    Glenister, P.H.2
  • 156
    • 34547093857 scopus 로고    scopus 로고
    • Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility
    • Walters KA, Allan CM, Jimenez M, Lim PR, Davey RA, Zajac JD, Illingworth P, Handelsman DJ. Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility. Endocrinology 2007; 148: 3674-3684.
    • (2007) Endocrinology , vol.148 , pp. 3674-3684
    • Walters, K.A.1    Allan, C.M.2    Jimenez, M.3    Lim, P.R.4    Davey, R.A.5    Zajac, J.D.6    Illingworth, P.7    Handelsman, D.J.8
  • 157
    • 67649642147 scopus 로고    scopus 로고
    • Subfertile female androgen receptor knockout mice exhibit defects in neuroendocrine signaling, intraovarian function, and uterine development but not uterine function
    • Walters KA, McTavish KJ, Seneviratne MG, Jimenez M, McMahon AC, Allan CM, Salamonsen LA, Handelsman DJ. Subfertile female androgen receptor knockout mice exhibit defects in neuroendocrine signaling, intraovarian function, and uterine development but not uterine function. Endocrinology 2009; 150:3274-3282.
    • (2009) Endocrinology , vol.150 , pp. 3274-3282
    • Walters, K.A.1    McTavish, K.J.2    Seneviratne, M.G.3    Jimenez, M.4    McMahon, A.C.5    Allan, C.M.6    Salamonsen, L.A.7    Handelsman, D.J.8
  • 158
    • 28244487293 scopus 로고    scopus 로고
    • Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium
    • Arango NA, Szotek PP, Manganaro TF, Oliva E, Donahoe PK, Teixeira J. Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium. Dev Biol 2005; 288:276-283.
    • (2005) Dev Biol , vol.288 , pp. 276-283
    • Arango, N.A.1    Szotek, P.P.2    Manganaro, T.F.3    Oliva, E.4    Donahoe, P.K.5    Teixeira, J.6
  • 160
    • 0036219918 scopus 로고    scopus 로고
    • Androgen receptor (AR) coregulators: an overview
    • Heinlein CA, Chang C. Androgen receptor (AR) coregulators: an overview. Endocr Rev 2002; 23:175-200.
    • (2002) Endocr Rev , vol.23 , pp. 175-200
    • Heinlein, C.A.1    Chang, C.2
  • 161
    • 0034714893 scopus 로고    scopus 로고
    • Interactions between androgen and estrogen receptors and the effects on their transactivational properties
    • Panet-Raymond V, Gottlieb B, Beitel LK, Pinsky L, Trifiro MA. Interactions between androgen and estrogen receptors and the effects on their transactivational properties. Mol Cell Endocrinol 2000; 167: 139-150.
    • (2000) Mol Cell Endocrinol , vol.167 , pp. 139-150
    • Panet-Raymond, V.1    Gottlieb, B.2    Beitel, L.K.3    Pinsky, L.4    Trifiro, M.A.5
  • 163
    • 0017147968 scopus 로고
    • Uterotrophic effects of testosterone and 5alpha-dihydrotestosterone in intact and ovariectomized immature female rats
    • Armstrong DT, Moon YS, Leung PC. Uterotrophic effects of testosterone and 5alpha-dihydrotestosterone in intact and ovariectomized immature female rats. Biol Reprod 1976; 15:107-114.
    • (1976) Biol Reprod , vol.15 , pp. 107-114
    • Armstrong, D.T.1    Moon, Y.S.2    Leung, P.C.3
  • 164
    • 1942476848 scopus 로고    scopus 로고
    • Uterine androgen receptors: roles in estrogen-mediated gene expression and DNA synthesis
    • Kowalski AA, Vale-Cruz DS, Simmen FA, Simmen RC. Uterine androgen receptors: roles in estrogen-mediated gene expression and DNA synthesis. Biol Reprod 2004; 70:1349-1357.
    • (2004) Biol Reprod , vol.70 , pp. 1349-1357
    • Kowalski, A.A.1    Vale-Cruz, D.S.2    Simmen, F.A.3    Simmen, R.C.4
  • 165
    • 0035992896 scopus 로고    scopus 로고
    • Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus
    • Weihua Z, Ekman J, Almkvist A, Saji S, Wang L, Warner M, Gustafsson JA. Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus. Biol Reprod 2002; 67:616-623.
    • (2002) Biol Reprod , vol.67 , pp. 616-623
    • Weihua, Z.1    Ekman, J.2    Almkvist, A.3    Saji, S.4    Wang, L.5    Warner, M.6    Gustafsson, J.A.7
  • 167
    • 0036050214 scopus 로고    scopus 로고
    • Anti-proliferative effects of progesterone antagonists in the primate endometrium: a potential role for the androgen receptor
    • Brenner RM, Slayden OD, Critchley HO. Anti-proliferative effects of progesterone antagonists in the primate endometrium: a potential role for the androgen receptor. Reproduction 2002; 124:167-172.
    • (2002) Reproduction , vol.124 , pp. 167-172
    • Brenner, R.M.1    Slayden, O.D.2    Critchley, H.O.3
  • 169
    • 0037240919 scopus 로고    scopus 로고
    • Regulation of HOXA-10 expression by testosterone in vitro and in the endometrium of patients with polycystic ovary syndrome
    • Cermik D, Selam B, Taylor HS. Regulation of HOXA-10 expression by testosterone in vitro and in the endometrium of patients with polycystic ovary syndrome. J Clin Endocrinol Metab 2003; 88:238-243.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 238-243
    • Cermik, D.1    Selam, B.2    Taylor, H.S.3
  • 170
    • 0025309530 scopus 로고
    • The cytomegalovirus enhancer: a pan-active control element in transgenic mice
    • Schmidt EV, Christoph G, Zeller R, Leder P. The cytomegalovirus enhancer: a pan-active control element in transgenic mice. Mol Cell Biol 1990; 10:4406-4411.
    • (1990) Mol Cell Biol , vol.10 , pp. 4406-4411
    • Schmidt, E.V.1    Christoph, G.2    Zeller, R.3    Leder, P.4
  • 171
    • 29744441949 scopus 로고    scopus 로고
    • Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model
    • Notini AJ, Davey RA, McManus JF, Bate KL, Zajac JD. Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model. J Mol Endocrinol 2005; 35:547-555.
    • (2005) J Mol Endocrinol , vol.35 , pp. 547-555
    • Notini, A.J.1    Davey, R.A.2    McManus, J.F.3    Bate, K.L.4    Zajac, J.D.5
  • 172
    • 84864447342 scopus 로고    scopus 로고
    • Minireview: the androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene?
    • Hickey TE, Robinson JL, Carroll JS, Tilley WD. Minireview: the androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene? Mol Endocrinol 2012; 26:1252-1267.
    • (2012) Mol Endocrinol , vol.26 , pp. 1252-1267
    • Hickey, T.E.1    Robinson, J.L.2    Carroll, J.S.3    Tilley, W.D.4
  • 173
    • 0036126095 scopus 로고    scopus 로고
    • Roles of androgens in the development, growth, and carcinogenesis of the mammary gland
    • Liao DJ, Dickson RB. Roles of androgens in the development, growth, and carcinogenesis of the mammary gland. J Steroid Biochem Mol Biol 2002; 80:175-189.
    • (2002) J Steroid Biochem Mol Biol , vol.80 , pp. 175-189
    • Liao, D.J.1    Dickson, R.B.2
  • 174
    • 0018841904 scopus 로고
    • Specificity of tissue interaction and origin of mesenchymal cells in the androgen response of the embryonic mammary gland
    • Durnberger H, Kratochwil K. Specificity of tissue interaction and origin of mesenchymal cells in the androgen response of the embryonic mammary gland. Cell 1980; 19:465-471.
    • (1980) Cell , vol.19 , pp. 465-471
    • Durnberger, H.1    Kratochwil, K.2
  • 175
    • 15844426173 scopus 로고    scopus 로고
    • Role of stromal-epithelial interactions in hormonal responses
    • Cunha GR, Cooke PS, Kurita T. Role of stromal-epithelial interactions in hormonal responses. Arch Histol Cytol 2004; 67:417-434.
    • (2004) Arch Histol Cytol , vol.67 , pp. 417-434
    • Cunha, G.R.1    Cooke, P.S.2    Kurita, T.3
  • 176
    • 0017346383 scopus 로고
    • Regression of mouse mammary gland anlagen in recombinants of Tfm and wild-type tissues: testosterone acts via the mesenchyme
    • Drews U. Regression of mouse mammary gland anlagen in recombinants of Tfm and wild-type tissues: testosterone acts via the mesenchyme. Cell 1977; 10:401-404.
    • (1977) Cell , vol.10 , pp. 401-404
    • Drews, U.1
  • 177
    • 0019870290 scopus 로고
    • Inhibition of DNA synthesis in mouse epidermis and breast epithelium by dehydroepiandrosterone and related steroids
    • Pashko LL, Schwartz AG, Abou-Gharbia M, Swern D. Inhibition of DNA synthesis in mouse epidermis and breast epithelium by dehydroepiandrosterone and related steroids. Carcinogenesis 1981; 2:717-721.
    • (1981) Carcinogenesis , vol.2 , pp. 717-721
    • Pashko, L.L.1    Schwartz, A.G.2    Abou-Gharbia, M.3    Swern, D.4
  • 179
    • 0016433584 scopus 로고
    • Effect of testosterone and estradiol-17beta on synthesis of DNA, RNA and protein in human breast in organ culture
    • Finkelstein M, Geier A, Horn H, Levij IS, Ever-Hadani P. Effect of testosterone and estradiol-17beta on synthesis of DNA, RNA and protein in human breast in organ culture. Int J Cancer 1975; 15:78-90.
    • (1975) Int J Cancer , vol.15 , pp. 78-90
    • Finkelstein, M.1    Geier, A.2    Horn, H.3    Levij, I.S.4    Ever-Hadani, P.5
  • 181
    • 0033818180 scopus 로고    scopus 로고
    • Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression
    • Zhou J, Ng S, Adesanya-Famuiya O, Anderson K, Bondy CA. Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression. FASEB J 2000; 14: 1725-1730.
    • (2000) FASEB J , vol.14 , pp. 1725-1730
    • Zhou, J.1    Ng, S.2    Adesanya-Famuiya, O.3    Anderson, K.4    Bondy, C.A.5
  • 182
    • 9144242999 scopus 로고    scopus 로고
    • Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor
    • Yeh S, Hu YC, Wang PH, Xie C, Xu Q, Tsai MY, Dong Z, Wang RS, Lee TH, Chang C. Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor. J Exp Med 2003; 198:1899-1908.
    • (2003) J Exp Med , vol.198 , pp. 1899-1908
    • Yeh, S.1    Hu, Y.C.2    Wang, P.H.3    Xie, C.4    Xu, Q.5    Tsai, M.Y.6    Dong, Z.7    Wang, R.S.8    Lee, T.H.9    Chang, C.10
  • 183
    • 0033847571 scopus 로고    scopus 로고
    • IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis
    • Kleinberg DL, Feldman M, Ruan W. IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis. J Mammary Gland Biol Neoplasia 2000; 5:7-17.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 7-17
    • Kleinberg, D.L.1    Feldman, M.2    Ruan, W.3
  • 184
    • 0034748607 scopus 로고    scopus 로고
    • Targeted disruption of the IGF-I receptor gene decreases cellular proliferation in mammary terminal end buds
    • Bonnette SG, Hadsell DL. Targeted disruption of the IGF-I receptor gene decreases cellular proliferation in mammary terminal end buds. Endocrinology 2001; 142:4937-4945.
    • (2001) Endocrinology , vol.142 , pp. 4937-4945
    • Bonnette, S.G.1    Hadsell, D.L.2
  • 187
    • 0031047821 scopus 로고    scopus 로고
    • Transcriptional regulation of the hepatocyte growth factor gene by the nuclear receptors chicken ovalbumin upstream promoter transcription factor and estrogen receptor
    • Jiang JG, Bell A, Liu Y, Zarnegar R. Transcriptional regulation of the hepatocyte growth factor gene by the nuclear receptors chicken ovalbumin upstream promoter transcription factor and estrogen receptor. J Biol Chem 1997; 272:3928-3934.
    • (1997) J Biol Chem , vol.272 , pp. 3928-3934
    • Jiang, J.G.1    Bell, A.2    Liu, Y.3    Zarnegar, R.4
  • 189
    • 0032547843 scopus 로고    scopus 로고
    • Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis
    • Niemann C, Brinkmann V, Spitzer E, Hartmann G, Sachs M, Naundorf H, Birchmeier W. Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis. J Cell Biol 1998; 143:533-545.
    • (1998) J Cell Biol , vol.143 , pp. 533-545
    • Niemann, C.1    Brinkmann, V.2    Spitzer, E.3    Hartmann, G.4    Sachs, M.5    Naundorf, H.6    Birchmeier, W.7
  • 190
    • 84889048064 scopus 로고    scopus 로고
    • Complete androgen insensitivity syndrome: a rare case of disorder of sex development
    • Pizzo A, Lagana AS, Borrielli I, Dugo N. Complete androgen insensitivity syndrome: a rare case of disorder of sex development. Case Rep Obstet Gynecol 2013; 2013:232696.
    • (2013) Case Rep Obstet Gynecol , vol.2013 , pp. 232696
    • Pizzo, A.1    Lagana, A.S.2    Borrielli, I.3    Dugo, N.4
  • 191
    • 4944265617 scopus 로고    scopus 로고
    • Epithelial-stromal interactions in the mouse and human mammary gland in vivo
    • Parmar H, Cunha GR. Epithelial-stromal interactions in the mouse and human mammary gland in vivo. Endocr Relat Cancer 2004; 11:437-458.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 437-458
    • Parmar, H.1    Cunha, G.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.