The effect of testosterone on androgen receptors and human penile growth

Journal of Urology

Volumn 158, Issue 3 SUPPL., 1997, Pages 1113-1118

  Baskin, Laurence S ^a   Sutherland, Ronald S ^a   DiSandro, Michael J ^a   Hayward, Simon W ^a   Lipschutz, Joshua ^a   Cunha, Gerald R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Androgen; Fetal development; Penis; Receptors; Testosterone

Indexed keywords

ANDROGEN RECEPTOR; TESTOSTERONE; TESTOSTERONE PROPIONATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FETUS; FETUS DEVELOPMENT; HISTOPATHOLOGY; HORMONAL REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; NORMAL HUMAN; PENIS; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; TISSUE GROWTH;

EID: 0030791558     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)64400-8     Document Type: Article

References (33)

1. Conte F. Grumbach M. Pathogenesis, classification, diagnosis and treatment of anomalies of sex. L.J. DeGroot Endocrinology 3rd ed 1995 W. B. Saunders Co. Philadelphia 618 670 chapt. 29
2. Quigley C.A. De Bellis A. Marschke K.B. El-Awady M.K. Wilson E.M. French F.S. Androgen receptor defects: historical, clinical, and molecular perspectives. Endocr. Rev. 16 1995 271
3. Hinman F.J. Penis and male urethra. UroSurgical Anatomy 1993 W. B. Saunders Co. Philadelphia 418 chapt. 16
4. Aaronson I.A. Micropenis: medical and surgical implications. J. Urol. 152 1994 4
5. Burstein S. Grumbach M.M. Kaplan S.L. Early determination of androgen-responsiveness is important in the management of microphallus. Lancet 2 1979 983
6. Hinman F. Jr. Surgical management of microphallus. J. Urol. 105 1971 901
7. Husmann D.A. Cain M.P. Microphallus: eventual phallic size is dependent on the timing of androgen administration. J. Urol. 152 1994 734 part 2
8. Takane K. George F. Wilson J.D. Androgen receptor of the rat penis is down-regulated by androgen. Amer. J. Phys. 258 1990 E46
9. Shen R. Lin M.C. Sadeghi F. Swerdloff R.S. Rajfer J. Gonzalez-Cadavid N.F. Androgens are not major down-regulators of androgen receptor levels during growth of the immature rat penis. J. Steroid Biochem. Mol. Biol. 57 1996 301
10. Husmann D. Androgen receptor expression and penile growth during sexual maturation. Dial. Ped. Urol. 19 1996 number 5
11. Sutherland R.S. Kogan B.A. Baskin L.S. Mevorach R.A. Conte F. Kaplan S.L. Grumbach M.M. The effect of prepubertal androgen exposure on adult penile length. J. Urol. 156 1996 783 part 2
12. Levy J.B. Husmann D.A. Congenital adrenal hyperplasia: is there an effect on penile growth? J. Urol. 156 1996 780 part 2
13. Hern W.M. Correlation of fetal age and measurements between 10 and 26 weeks of gestation. Obst. Gynec. 63 1984 26
14. Munsick R.A. Human fetal extremity lengths in the interval from 9 to 21 menstrual weeks of pregnancy. Amer. J. Obst. Gynec. 149 1984 883
15. Robboy S.J. Taguchi O. Cunha G.R. Normal development of the human female reproductive tract and alterations resulting from experimental exposure to diethylstilbestrol. Hum. Path. 13 1982 190
16. Baskin L.S. Hayward S. Young P. Cunha G. Role of mesenchymal-epithelial interactions in normal bladder development. J. Urol. 156 1996 1820
17. Prins G.S. Birch L. Greene G. Androgen receptor localization in different cell types of the adult rat prostate. Endocrinology 129 1991 3187
18. George F. Wilson J. Sex determination and differentiation. E. Knobil J. Neill The Physiology of Reproduction 1994 Raven New York 114 160 chapt. 3
19. Schonfeld W. Beebe G. Normal growth and variation in the male genitalia from birth to maturity. J. Urol. 48 1942 759
20. Donjacour A.A. Cunha G.R. The effect of androgen deprivation on branching morphogenesis in the mouse prostate. Devel. Biol. 128 1988 1
21. Cooke P.S. Young P. Cunha G.R. Androgen receptor expression in developing male reproductive organs. Endocrinology 128 1991 2867
22. Shima H. Tsuji M. Young P.F. Cunha G.R. Postnatal growth of mouse seminal vesicle is dependent on 5 alpha-dihydrotestosterone. Endocrinology 127 1990 3222
23. Chung L.W.K. Cunha G.R. Stromal-epithelial interactions. II. Regulation of prostatic growth by embryonic urogenital sinus mesenchyme. Prostate 4 1983 503
24. Neubauer B.L. Best K.L. Hoover D.M. Slisz M.L. Van Frank R.M. Goode R.L. Mesenchymal-epithelial interactions as factors influencing male accessory sex organ growth in the rat. Fed. Proc. 45 1986 2618
25. Cunha G.R. Foster B.A. Sugimura Y. Hom Y.K. Keratinocyte growth factor as mediator of mesenchymal-epithelial interactions in the development of androgen target organs. Sem. Cell Dev. Biol. 7 1996 203
26. Hayward S.W. Cunha G.R. Dahiya R. Normal development and carcinogenesis of the prostate. A unifying hypothesis. Ann. N. Y. Acad. Sci. 784 1996 50
27. Roehrborn C.G. Lange J.L. George F.W. Wilson J.D. Changes in amount and intracellular distribution of androgen receptor in human foreskin as a function of age. J. Clin. Invest. 79 1987 44
28. Herber S.M. Milner R.D. Growth hormone deficiency presenting under age 2 years. Arch. Dis. Child. 59 1984 557
29. Lee P.A. Mazur T. Danish R. Amrhein J. Blizzard R.M. Money J. Migeon C.J. Micropenis. I. Criteria, etiologies and classification. Johns Hopkins Med. J. 146 1980 156
30. Laron Z. Sarel R. Penis and testicular size in patients with growth hormone insufficiency. Acta Endocr. 63 1970 625
31. Isaksson O.G. Lindahl A. Nilsson A. Isgaard J. Action of growth hormone: current views. Acta Paed. Scand. 343 suppl. 1988 12
32. Rosenfeld R.G. Rosenbloom A.L. Guevara-Aguirre J. Growth hormone (GH) insensitivity due to primary GH receptor deficiency. Endocr. Rev. 15 1994 369
33. Levy J.B. Husmann D.A. Micropenis secondary to growth hormone deficiency: does treatment with growth hormone alone result in adequate penile growth? J. Urol. 156 1996 214