메뉴 건너뛰기




Volumn 139, Issue 1, 2010, Pages 177-184

Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; RECOMBINANT FOLLITROPIN; TESTOSTERONE;

EID: 75149163369     PISSN: 14701626     EISSN: 17417899     Source Type: Journal    
DOI: 10.1530/REP-09-0377     Document Type: Article
Times cited : (101)

References (50)
  • 1
    • 0034457577 scopus 로고    scopus 로고
    • The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction
    • Abel MH, Wootton AN, Wilkins V, Huhtaniemi I, Knight PG & Charlton HM 2000 The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction. Endocrinology 141 1795-1803.
    • (2000) Endocrinology , vol.141 , pp. 1795-1803
    • Abel, M.H.1    Wootton, A.N.2    Wilkins, V.3    Huhtaniemi, I.4    Knight, P.G.5    Charlton, H.M.6
  • 3
    • 67449164713 scopus 로고    scopus 로고
    • Effects of follicle stimulating hormone on testicular mRNA transcript levels in the hypogonadal mouse
    • Abel M, Baban D, Lee S, Charlton H & O'Shaughnessy P 2009 Effects of follicle stimulating hormone on testicular mRNA transcript levels in the hypogonadal mouse. Journal of Molecular Endocrinology 42 291-303.
    • (2009) Journal of Molecular Endocrinology , vol.42 , pp. 291-303
    • Abel, M.1    Baban, D.2    Lee, S.3    Charlton, H.4    O'Shaughnessy, P.5
  • 5
    • 0034908014 scopus 로고    scopus 로고
    • Role of gonadotrophins in regulating numbers of Leydig and Sertoli cells during fetal and postnatal development in mice
    • Baker PJ & O'Shaughnessy PJ 2001 Role of gonadotrophins in regulating numbers of Leydig and Sertoli cells during fetal and postnatal development in mice. Reproduction 122 227-234.
    • (2001) Reproduction , vol.122 , pp. 227-234
    • Baker, P.J.1    O'Shaughnessy, P.J.2
  • 6
    • 0037225516 scopus 로고    scopus 로고
    • Failure of normal Leydig cell development in follicle-stimulating hormone (FSH) receptor-deficient mice, but not FSHb-deficient mice: Role for constitutive FSH receptor activity
    • Baker PJ, Pakarinen P, Huhtaniemi IT, Abel MH, Charlton HM, Kumar TR & O'Shaughnessy PJ 2003 Failure of normal Leydig cell development in follicle-stimulating hormone (FSH) receptor-deficient mice, but not FSHb-deficient mice: role for constitutive FSH receptor activity. Endocrinology 144 138-145.
    • (2003) Endocrinology , vol.144 , pp. 138-145
    • Baker, P.J.1    Pakarinen, P.2    Huhtaniemi, I.T.3    Abel, M.H.4    Charlton, H.M.5    Kumar, T.R.6    O'Shaughnessy, P.J.7
  • 7
    • 0028103854 scopus 로고
    • Immunohistochemical localization of androgen receptors in the rat testis: Evidence for stage-dependent expression and regulation by androgens
    • Bremner WJ, Millar MR, Sharpe RM & Saunders PT 1994 Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens. Endocrinology 135 1227-1234.
    • (1994) Endocrinology , vol.135 , pp. 1227-1234
    • Bremner, W.J.1    Millar, M.R.2    Sharpe, R.M.3    Saunders, P.T.4
  • 8
    • 0017655350 scopus 로고
    • Gonadotrophin releasing hormone deficiency in a mutant mouse with hypogonadism
    • Cattanach BM, Iddon CA, Charlton HM, Chiappa SA & Fink G 1977 Gonadotrophin releasing hormone deficiency in a mutant mouse with hypogonadism. Nature 269 338-340.
    • (1977) Nature , vol.269 , pp. 338-340
    • Cattanach, B.M.1    Iddon, C.A.2    Charlton, H.M.3    Chiappa, S.A.4    Fink, G.5
  • 12
    • 0032506018 scopus 로고    scopus 로고
    • Impairing follicle-stimulating hormone (FSH) signaling in vivo: Targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance
    • Dierich A, Sairam MR, Monaco L, Fimia GM, Gansmuller A, LeMeur M & Sassone-Corsi P 1998 Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance. PNAS 95 13612-13617.
    • (1998) PNAS , vol.95 , pp. 13612-13617
    • Dierich, A.1    Sairam, M.R.2    Monaco, L.3    Fimia, G.M.4    Gansmuller, A.5    LeMeur, M.6    Sassone-Corsi, P.7
  • 13
    • 0000962118 scopus 로고
    • Effects of two hypophyseal gonadotrophic hormones on the reproductive system of the male rat
    • Greep RO, Fevold HL & Hisaw FL 1936 Effects of two hypophyseal gonadotrophic hormones on the reproductive system of the male rat. Anatomical Record 65 261-270.
    • (1936) Anatomical Record , vol.65 , pp. 261-270
    • Greep, R.O.1    Fevold, H.L.2    Hisaw, F.L.3
  • 14
    • 0037318477 scopus 로고    scopus 로고
    • Sertoli and germ cell development in hypogonadal (hpg) mice expressing transgenic follicle-stimulating hormone alone or in combination with testosterone
    • Haywood M, Spaliviero J, Jimemez M, King NJ, Handelsman DJ & Allan CM 2003 Sertoli and germ cell development in hypogonadal (hpg) mice expressing transgenic follicle-stimulating hormone alone or in combination with testosterone. Endocrinology 144 509-517.
    • (2003) Endocrinology , vol.144 , pp. 509-517
    • Haywood, M.1    Spaliviero, J.2    Jimemez, M.3    King, N.J.4    Handelsman, D.J.5    Allan, C.M.6
  • 15
    • 0015222079 scopus 로고
    • Follicle-stimulating hormone and the regulation of testosterone secretion in rabbit testes
    • Johnson BH & Ewing LL 1971 Follicle-stimulating hormone and the regulation of testosterone secretion in rabbit testes. Science 173 635-637.
    • (1971) Science , vol.173 , pp. 635-637
    • Johnson, B.H.1    Ewing, L.L.2
  • 16
    • 0345827710 scopus 로고    scopus 로고
    • Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse
    • Johnston H, Baker PJ, Abel M, Charlton HM, Jackson G, Fleming L, Kumar TR & O'Shaughnessy PJ 2004 Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse. Endocrinology 145 318-329.
    • (2004) Endocrinology , vol.145 , pp. 318-329
    • Johnston, H.1    Baker, P.J.2    Abel, M.3    Charlton, H.M.4    Jackson, G.5    Fleming, L.6    Kumar, T.R.7    O'Shaughnessy, P.J.8
  • 17
    • 0032152031 scopus 로고    scopus 로고
    • Ram lambs need FSH for normal testicular growth, Sertoli cell numbers and onset of spermatogenesis
    • Kilgour RJ, Pisselet C, Dubois MP & Courot M 1998 Ram lambs need FSH for normal testicular growth, Sertoli cell numbers and onset of spermatogenesis. Reproduction, Nutrition, Development 38 539-550.
    • (1998) Reproduction, Nutrition, Development , vol.38 , pp. 539-550
    • Kilgour, R.J.1    Pisselet, C.2    Dubois, M.P.3    Courot, M.4
  • 18
    • 0034088783 scopus 로고    scopus 로고
    • Qualitative and quantitative decline in spermatogenesis of the follicle-stimulating hormone receptor knockout (FORKO) mouse
    • Krishnamurthy H, Danilovich N, Morales CR & Sairam MR 2000 Qualitative and quantitative decline in spermatogenesis of the follicle-stimulating hormone receptor knockout (FORKO) mouse. Biology of Reproduction 62 1146-1159.
    • (2000) Biology of Reproduction , vol.62 , pp. 1146-1159
    • Krishnamurthy, H.1    Danilovich, N.2    Morales, C.R.3    Sairam, M.R.4
  • 19
    • 0031054284 scopus 로고    scopus 로고
    • Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility
    • Kumar TR, Wang Y, Lu N & Matzuk MM 1997 Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nature Genetics 15 201-204.
    • (1997) Nature Genetics , vol.15 , pp. 201-204
    • Kumar, T.R.1    Wang, Y.2    Lu, N.3    Matzuk, M.M.4
  • 20
    • 0001292496 scopus 로고
    • Assay for deletion in GnRH (hpg) locus using PCR
    • Lang J 1991 Assay for deletion in GnRH (hpg) locus using PCR. Mouse Genetics 89 857.
    • (1991) Mouse Genetics , vol.89 , pp. 857
    • Lang, J.1
  • 22
    • 0036327168 scopus 로고    scopus 로고
    • Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice
    • Lecureuil C, Fontaine I, Crepieux P & Guillou F 2002 Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice. Genesis 33 114-118.
    • (2002) Genesis , vol.33 , pp. 114-118
    • Lecureuil, C.1    Fontaine, I.2    Crepieux, P.3    Guillou, F.4
  • 24
    • 0031712880 scopus 로고    scopus 로고
    • Follitropin (FSH) deficiency in an infertile male due to FSHb gene mutation. A syndrome of normal puberty and virilization but under-developed testicles with azoospermia, low FSH but high lutropin and normal serum testosterone concentrations
    • Lindstedt G, Nystrom E, Matthews C, Ernest I, Janson PO & Chatterjee K 1998 Follitropin (FSH) deficiency in an infertile male due to FSHb gene mutation. A syndrome of normal puberty and virilization but under-developed testicles with azoospermia, low FSH but high lutropin and normal serum testosterone concentrations. Clinical Chemistry and Laboratory Medicine 36 663-665.
    • (1998) Clinical Chemistry and Laboratory Medicine , vol.36 , pp. 663-665
    • Lindstedt, G.1    Nystrom, E.2    Matthews, C.3    Ernest, I.4    Janson, P.O.5    Chatterjee, K.6
  • 25
    • 0023031013 scopus 로고
    • Maintenance of complete but quantitatively reduced spermatogenesis in hypophysectomized monkeys by testosterone alone
    • Marshall GR, Jockenhövel F, Lüdecke D & Nieschlag E 1986 Maintenance of complete but quantitatively reduced spermatogenesis in hypophysectomized monkeys by testosterone alone. Acta Endocrinologica 113 424-431.
    • (1986) Acta Endocrinologica , vol.113 , pp. 424-431
    • Marshall, G.R.1    Jockenhövel, F.2    Lüdecke, D.3    Nieschlag, E.4
  • 26
    • 0029143454 scopus 로고
    • Follicle-stimulating hormone amplifies the population of differentiated spermatogonia in the hypophysectomized testosterone-replaced adult rhesus monkey (Macaca mulatta)
    • Marshall GR, Zorub DS & Plant TM 1995 Follicle-stimulating hormone amplifies the population of differentiated spermatogonia in the hypophysectomized testosterone-replaced adult rhesus monkey (Macaca mulatta). Endocrinology 136 3504-3511.
    • (1995) Endocrinology , vol.136 , pp. 3504-3511
    • Marshall, G.R.1    Zorub, D.S.2    Plant, T.M.3
  • 27
    • 0028264206 scopus 로고
    • Effects of recombinant human FSH in immature hypophysectomized male rats: Evidence for Leydig cell-mediated action on spermatogenesis
    • Matikainen T, Toppari J, Vihko KK & Huhtaniemi I 1994 Effects of recombinant human FSH in immature hypophysectomized male rats: evidence for Leydig cell-mediated action on spermatogenesis. Journal of Endocrinology 141 449-457.
    • (1994) Journal of Endocrinology , vol.141 , pp. 449-457
    • Matikainen, T.1    Toppari, J.2    Vihko, K.K.3    Huhtaniemi, I.4
  • 28
    • 0026517873 scopus 로고
    • A review of recent advances in stereology for quantifying neural structure
    • Mayhew TM 1992 A review of recent advances in stereology for quantifying neural structure. Journal of Neurocytology 21 313-328.
    • (1992) Journal of Neurocytology , vol.21 , pp. 313-328
    • Mayhew, T.M.1
  • 29
    • 0029084589 scopus 로고
    • The effects of recombinant follicle-stimulating hormone on the restoration of spermatogenesis in the gonadotropin-releasing hormone-immunized adult rat
    • McLachlan RI, Wreford NG, de Kretser DM & Robertson DM 1995 The effects of recombinant follicle-stimulating hormone on the restoration of spermatogenesis in the gonadotropin-releasing hormone-immunized adult rat. Endocrinology 136 4035-4043.
    • (1995) Endocrinology , vol.136 , pp. 4035-4043
    • McLachlan, R.I.1    Wreford, N.G.2    de Kretser, D.M.3    Robertson, D.M.4
  • 30
    • 33847639684 scopus 로고    scopus 로고
    • Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation
    • Merlet J, Racine C, Moreau E, Moreno SG & Habert R 2007 Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation. PNAS 104 3615-3620.
    • (2007) PNAS , vol.104 , pp. 3615-3620
    • Merlet, J.1    Racine, C.2    Moreau, E.3    Moreno, S.G.4    Habert, R.5
  • 31
    • 29644445928 scopus 로고    scopus 로고
    • Atypical development of Sertoli cells and impairment of spermatogenesis in the hypogonadal (hpg) mouse
    • Myers M, Ebling FJ, Nwagwu M, Boulton R, Wadhwa K, Stewart J & Kerr JB 2005 Atypical development of Sertoli cells and impairment of spermatogenesis in the hypogonadal (hpg) mouse. Journal of Anatomy 207 797-811.
    • (2005) Journal of Anatomy , vol.207 , pp. 797-811
    • Myers, M.1    Ebling, F.J.2    Nwagwu, M.3    Boulton, R.4    Wadhwa, K.5    Stewart, J.6    Kerr, J.B.7
  • 32
    • 0025288425 scopus 로고
    • Effect of testosterone on testicular steroidogenesis in the hypogonadal (hpg) mouse
    • O'Shaughnessy PJ & Sheffield JW 1990 Effect of testosterone on testicular steroidogenesis in the hypogonadal (hpg) mouse. Journal of Steroid Biochemistry 35 729-734.
    • (1990) Journal of Steroid Biochemistry , vol.35 , pp. 729-734
    • O'Shaughnessy, P.J.1    Sheffield, J.W.2
  • 35
  • 36
    • 45249123233 scopus 로고    scopus 로고
    • Effect of germ cell depletion on levels of specific mRNA transcripts in mouse Sertoli cells and Leydig cells
    • O'Shaughnessy PJ, Hu L & Baker PJ 2008 Effect of germ cell depletion on levels of specific mRNA transcripts in mouse Sertoli cells and Leydig cells. Reproduction 135 839-850.
    • (2008) Reproduction , vol.135 , pp. 839-850
    • O'Shaughnessy, P.J.1    Hu, L.2    Baker, P.J.3
  • 38
    • 0032508059 scopus 로고    scopus 로고
    • Male hypogonadism due to a mutation in the gene for the b-subunit of follicle-stimulating hormone
    • Phillip M, Arbelle JE, Segev Y & Parvari R 1998 Male hypogonadism due to a mutation in the gene for the b-subunit of follicle-stimulating hormone. New England Journal of Medicine 338 1729-1732.
    • (1998) New England Journal of Medicine , vol.338 , pp. 1729-1732
    • Phillip, M.1    Arbelle, J.E.2    Segev, Y.3    Parvari, R.4
  • 40
    • 0027367277 scopus 로고
    • Recombinant human follicle-stimulating hormone is capable of exerting a biological effect in the adult hypophysectomized rat by reducing the numbers of degenerating germ cells
    • Russell LD, Corbin TJ, Borg KE, De Franca LR, Grasso P & Bartke A 1993 Recombinant human follicle-stimulating hormone is capable of exerting a biological effect in the adult hypophysectomized rat by reducing the numbers of degenerating germ cells. Endocrinology 133 2062-2070.
    • (1993) Endocrinology , vol.133 , pp. 2062-2070
    • Russell, L.D.1    Corbin, T.J.2    Borg, K.E.3    De Franca, L.R.4    Grasso, P.5    Bartke, A.6
  • 41
    • 0031800536 scopus 로고    scopus 로고
    • Hormonal regulation of spermatogenesis in the hypophysectomized rat: FSH maintenance of cellular viability during pubertal spermatogenesis
    • Russell LD, Kershaw M, Borg KE, El Shennawy A, Rulli SS, Gates RJ & Calandra RS 1998 Hormonal regulation of spermatogenesis in the hypophysectomized rat: FSH maintenance of cellular viability during pubertal spermatogenesis. Journal of Andrology 19 308-319.
    • (1998) Journal of Andrology , vol.19 , pp. 308-319
    • Russell, L.D.1    Kershaw, M.2    Borg, K.E.3    El Shennawy, A.4    Rulli, S.S.5    Gates, R.J.6    Calandra, R.S.7
  • 42
    • 69149091351 scopus 로고    scopus 로고
    • A selective monotropic elevation of FSH, but not that of LH, amplifies the proliferation and differentiation of spermatogonia in the adult rhesus monkey (Macaca mulatta)
    • Simorangkir DR, Ramaswamy S, Marshall GR, Pohl CR & Plant TM 2009 A selective monotropic elevation of FSH, but not that of LH, amplifies the proliferation and differentiation of spermatogonia in the adult rhesus monkey (Macaca mulatta). Human Reproduction 24 1584-1595.
    • (2009) Human Reproduction , vol.24 , pp. 1584-1595
    • Simorangkir, D.R.1    Ramaswamy, S.2    Marshall, G.R.3    Pohl, C.R.4    Plant, T.M.5
  • 43
    • 0029838739 scopus 로고    scopus 로고
    • The effects of recombinant fsh on testosterone-induced spermatogenesis in gonadotropin-deficient (Hpg) mice
    • Singh J & Handelsman DJ 1996 The effects of recombinant fsh on testosterone-induced spermatogenesis in gonadotropin-deficient (Hpg) mice. Journal of Andrology 17 382-393.
    • (1996) Journal of Andrology , vol.17 , pp. 382-393
    • Singh, J.1    Handelsman, D.J.2
  • 44
    • 18844407557 scopus 로고    scopus 로고
    • The role of androgens in Sertoli cell proliferation and functional maturation: Studies in mice with total (ARKO) or Sertoli cell-selective (SCARKO) ablation of the androgen receptor
    • Tan KA, De Gendt K, Atanassova N, Walker M, Sharpe RM, Saunders PT, Denolet E & Verhoeven G 2005 The role of androgens in Sertoli cell proliferation and functional maturation: studies in mice with total (ARKO) or Sertoli cell-selective (SCARKO) ablation of the androgen receptor. Endocrinology 146 2674-2683.
    • (2005) Endocrinology , vol.146 , pp. 2674-2683
    • Tan, K.A.1    De Gendt, K.2    Atanassova, N.3    Walker, M.4    Sharpe, R.M.5    Saunders, P.T.6    Denolet, E.7    Verhoeven, G.8
  • 45
    • 1842376911 scopus 로고    scopus 로고
    • Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility
    • Tapanainen JS, Aittomaki K, Min J, Vaskivuo T & Huhtaniemi IT 1997 Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility. Nature Genetics 15 205-206.
    • (1997) Nature Genetics , vol.15 , pp. 205-206
    • Tapanainen, J.S.1    Aittomaki, K.2    Min, J.3    Vaskivuo, T.4    Huhtaniemi, I.T.5
  • 46
    • 0025996822 scopus 로고
    • Stimulatory effects of recombinant follicle-stimulating hormone on Leydig cell function and spermatogenesis in immature hypophysectomized rats
    • Vihko KK, Lapolt PS, Nishimori K & Hsueh AJ 1991 Stimulatory effects of recombinant follicle-stimulating hormone on Leydig cell function and spermatogenesis in immature hypophysectomized rats. Endocrinology 129 1926-1932.
    • (1991) Endocrinology , vol.129 , pp. 1926-1932
    • Vihko, K.K.1    Lapolt, P.S.2    Nishimori, K.3    Hsueh, A.J.4
  • 47
    • 72749101744 scopus 로고    scopus 로고
    • Androgen action via testicular peritubular myoid cells is essential for male fertility
    • in press, DOI: 10.1096/fj.09-138347
    • Welsh M, Saunders PT, Atanassova N, Sharpe RM & Smith LB 2009 Androgen action via testicular peritubular myoid cells is essential for male fertility. FASEB Journal [in press]. DOI: 10.1096/fj.09-138347.
    • (2009) FASEB Journal
    • Welsh, M.1    Saunders, P.T.2    Atanassova, N.3    Sharpe, R.M.4    Smith, L.B.5
  • 48
    • 0028832450 scopus 로고
    • Theory and practice of stereological techniques applied to the estimation of cell number and nuclear volume of the testis
    • Wreford NG 1995 Theory and practice of stereological techniques applied to the estimation of cell number and nuclear volume of the testis. Microscopy Research and Technique 32 423-436.
    • (1995) Microscopy Research and Technique , vol.32 , pp. 423-436
    • Wreford, N.G.1
  • 49
    • 0029991553 scopus 로고    scopus 로고
    • Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development
    • Zhou X, Kudo A, Kawakami H & Hirano H 1996 Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development. Anatomical Record 245 509-518.
    • (1996) Anatomical Record , vol.245 , pp. 509-518
    • Zhou, X.1    Kudo, A.2    Kawakami, H.3    Hirano, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.