Murine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation

Endocrinology

Volumn 142, Issue 6, 2001, Pages 2405-2408

  Johnston, Daniel S ^a   Russell, Lonnie D ^b   Friel, Patrick J ^a   Griswold, Michael D ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AZOOSPERMIA; CONTROLLED STUDY; FEMINIZATION; GERM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; SEMINIFEROUS TUBULE; SPERMATOGENESIS; SPERMATOGONIUM; STEM CELL TRANSPLANTATION; TESTIS;

ANIMALS; CELL DIFFERENTIATION; FEMALE; GENE DELETION; MALE; MICE; MICE, INBRED C57BL; MUTATION; OLIGOSPERMIA; POLYMERASE CHAIN REACTION; RECEPTORS, ANDROGEN; SEMINIFEROUS TUBULES; SPERMATOGENESIS; SPERMATOGONIA; SPERMATOZOA; STEM CELL TRANSPLANTATION; TESTIS;

EID: 0035000459     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.142.6.2405     Document Type: Article

References (25)

1. 1. Roberts KP, Zirkin BR 1991 Androgen regulation of spermatogenesis in the rat Ann N Y Acad Sci 637:90-106
2. 2. Sharpe RM 1994 The Regulation of Spermatogenesis. In: Knobil E and Neill JD (ed) The Physiology of Reproduction. Raven Press. New York, vol 1:1363-1434
3. 3. Anthony CT, Kovacs WJ, Skinner MK 1989 Analysis of the androgen receptor in isolated testicular cell types with a microassay that uses an affinity ligand. Endocrinology 125(5):2628-2635
4. 4. Galena HJ, Pillai AK, Terner C 1974 Progesterone and androgen receptors in non-flagellate germ cells of the rat testis. J. Endocrinol 63(1):223-237
5. 5. Sanborn BM, Steinberger A, Meistrich ML, Steinberger E 1975 Androgen binding sites in th testis cells fractions as measured by a nuclear exchange assay. J Steroid Biochem 6(11-12):1459-1465
6. 6. Wright WW, Frankel AI 1980 An androgen receptor in the nuclei of late spermatids in testes of male rats. Endocrinology 107:314-318
7. 7. Frankel AI, Chapman JC, Wright WW 1989 The equivocal presence of nuclear androgen binding proteins in mammalian spermatids and spermatozoa. J Steroid Biochem 33:71-79
8. 8. Vornberger W, Prins G, Musto NA, Suarez-Quian CA 1994 Androgen receptor distribution in rat testis: new implications for androgen regulation of spermatogenesis. Endocrinology;134(5):2307-16.
9. 9. Grootegoed JA, Peters MJ, Mulder E, Rommerts FF, Van der Molen HJ 1977 Absence of a nuclear androgen receptor in isolated germinal cells of rat testis. Mol Cell Endocrinol 9(2):159-167
10. 10. Bremner WJ, Millar MR, Sharpe RM, Saunders PT 1994 Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens. Endocrinology. 135(3):1227-1234
11. 11. Charest NJ, Zhou ZX, Lubahn DB, Olsen KL, Wilson EM, French FS 1991 A frameshift mutation destabilizes androgen receptor messenger RNA in the Tfm mouse. Mol Endocrinol 5(4): 573-581
12. 12. Lyon MF, Hawkes SG 1970 X-linked Gene for Testicular Feminization in the Mouse. Nature 227:1217-1219
13. 13. Dofuku R, Tettenborn U, Ohno S 1971 Testosterone-"regulon" in the mouse kidney. Nature 232:5-7
14. 14. Lyon MF, Hendry I, Short RV 1973 The submaxillary salivary glands as test organs for response to androgen in mice with testicular feminization. J Endocrinol 58:357-362
15. 15. Lyon MF, Glenister PH, Lynn Lamoreux M 1975 Normal spermatozoa from androgen-resistant germ cells of chimeric mice and the role of androgen in spermatogenesis. Nature258:620-622.
16. 16. Russell LD, Kershaw M, Borg KE, El Shennawy A, Rulli SS, Gates RJ, Calandra RS 1998 Hormonal Regulation of spermatogenesis in the hypophysectomized rat; FSH Maintenance of cellular viability during pubertal spermatogenesis. J. Androl. 19:308-319
17. 17. Boettger-Tong HL, Johnston DS, Russell LD, Griswold MD, Bishop CE 2000 Juvenile spermatogonial depletion (jsd) mutant seminiferous tubules are capable of supporting transplanted spermatogenesis. Biol Reprod 63(4):1185-1191
18. 18. Brinster RL, Avarbock MR 1994 Germline transmission of donor haplotype following spermatogonial transplantation. Proc Natl Acad Sci U S A 91(24):11303-11307
19. 19. Ogawa T, Arechaga JM, Avarbock MR, Brinster RL 1997 Transplantation of testis germinal cells into mouse seminiferous tubules. Int J. Dev Biol 41(1): 111-122
20. 20. Silvers WK 1979 The coat colors of mice: a model for mammalian gene action and interaction (Springer, New York), pp. 206-241
21. 21. Handel MA, Eppig JJ 1979 Sertoli cell differentiation in the testis of mice genetically deficient in germ cells. Biol Reprod 20(5):1031-1038
22. 22. Kuroda H, Nakayama H, Namiki M, Matsumoto K, Nishimune Y, Kitamura Y 1989 Differentiation of germ cells in seminiferous tubules transplanted to testis of germ cell-deficient mice of W/Wv and S1/S1d genotypes. J Cell Physiol 139(2):329-334
23. 23. Mizunuma M, Dohmae K, Tajima Y, Kosimizu U, Watanabe D, Nishimune Y 1992 Loss of sperm in juvenile spermatogonial depletion (jsd) mutant mice is ascribed to a defect of intratubular environment to support germ cell differentiation. J Cell Physiol 150: 188-93
24. 24. Dobrinski I, Ogawa T, Avarbock MR, Brinster RL 1999 Computer assisted image analysis to assess colonization of recipient seminiferous tubules by spermatogonial stem cells from transgenic donor mice. Mol Reprod Dev 53(2):142-148
25. 25. Shinohara T, Brinster RL 2000 Enrichment and transplantation of spermatogonial stem cells. Int J Androl 23 Suppl 2:89-91