Altered prostate epithelial development and IGF-1 signal in mice lacking the androgen receptor in stromal smooth muscle cells

Prostate

Volumn 71, Issue 5, 2011, Pages 517-524

  Yu, Shengqiang ^a,b   Zhang, Caixia ^a   Lin, Chiu Chun ^a   Niu, Yuanjie ^a,c   Lai, Kuo Pao ^a   Chang, Hong Chiang ^a   Yeh, Shauh Der ^a,d,e   Chang, Chawnshang ^a,f   Yeh, Shuyuan ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cre loxP; gene knockout; stroma; transgelin

Indexed keywords

ANDROGEN RECEPTOR; DNA; PROTEIN; RNA;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; STROMA CELL;

ANIMALS; APOPTOSIS; EPITHELIAL CELLS; EPITHELIUM; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCLE, SMOOTH; PROSTATE; RECEPTORS, ANDROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION;

EID: 79951527527     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21264     Document Type: Article

References (30)

1. Thomson AA,. Mesenchymal mechanisms in prostate organogenesis. Differentiation 2008; 76 (6): 587-598. (Pubitemid 352032749)
2. Cunha GR, Alarid ET, Turner T, Donjacour AA, Boutin EL, Foster BA,. Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors. J Androl 1992; 13 (6): 465-475.
3. Chang C, Saltzman A, Yeh S, Young W, Keller E, Lee HJ, Wang C, Mizokami A,. Androgen receptor: An overview. Crit Rev Eukaryot Gene Expr 1995; 5 (2): 97-125.
4. Chung LW, Cunha GR,. Stromal-epithelial interactions: II. Regulation of prostatic growth by embryonic urogenital sinus mesenchyme. Prostate 1983; 4 (5): 503-511. (Pubitemid 14236147)
5. Cunha GR,. Mesenchymal-epithelial interactions: Past, present, and future. Differentiation 2008; 76 (6): 578-586. (Pubitemid 352032745)
6. Shapiro E, Becich MJ, Hartanto V, Lepor H,. The relative proportion of stromal and epithelial hyperplasia is related to the development of symptomatic benign prostate hyperplasia. J Urol 1992; 147 (5): 1293-1297.
7. Cunha GR, Hayward SW, Dahiya R, Foster BA,. Smooth muscle-epithelial interactions in normal and neoplastic prostatic development. Acta Anat (Basel) 1996; 155 (1): 63-72. (Pubitemid 26193060)
8. Prins GS, Putz O,. Molecular signaling pathways that regulate prostate gland development. Differentiation 2008; 76 (6): 641-659. (Pubitemid 352032742)
9. Tuxhorn JA, Ayala GE, Rowley DR,. Reactive stroma in prostate cancer progression. J Urol 2001; 166 (6): 2472-2483. (Pubitemid 33065339)
10. Antonioli E, Della-Colleta HH, Carvalho HF,. Smooth muscle cell behavior in the ventral prostate of castrated rats. J Androl 2004; 25 (1): 50-56. (Pubitemid 38017785)
11. Yeh S, Tsai MY, Xu Q, Mu XM, Lardy H, Huang KE, Lin H, Yeh SD, Altuwaijri S, Zhou X, Xing L, Boyce BF, Hung MC, Zhang S, Gan L, Chang C,. Generation and characterization of androgen receptor knockout (ARKO) mice: An in vivo model for the study of androgen functions in selective tissues. Proc Natl Acad Sci USA 2002; 99 (21): 13498-13503. (Pubitemid 35215410)
12. Wu CT, Altuwaijri S, Ricke WA, Huang SP, Yeh S, Zhang C, Niu Y, Tsai MY, Chang C,. Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor. Proc Natl Acad Sci USA 2007; 104 (31): 12679-12684. (Pubitemid 47255214)
13. Gerdes MJ, Dang TD, Lu B, Larsen M, McBride L, Rowley DR,. Androgen-regulated proliferation and gene transcription in a prostate smooth muscle cell line (PS-1). Endocrinology 1996; 137 (3): 864-872. (Pubitemid 26070365)
14. Holtwick R, Gotthardt M, Skryabin B, Steinmetz M, Potthast R, Zetsche B, Hammer RE, Herz J, Kuhn M,. Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure. Proc Natl Acad Sci USA 2002; 99 (10): 7142-7147. (Pubitemid 34526269)
15. Zhang C, Yeh S, Chen YT, Wu CC, Chuang KH, Lin HY, Wang RS, Chang YJ, Mendis-Handagama C, Hu L, Lardy H, Chang C,. Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells. Proc Natl Acad Sci USA 2006; 103 (47): 17718-17723. (Pubitemid 44852226)
16. Yeh S, Hu YC, Wang PH, Xie C, Xu Q, Tsai MY, Dong Z, Wang RS, Lee TH, Chang C,. Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor. J Exp Med 2003; 198 (12): 1899-1908. (Pubitemid 38032122)
17. Soriano P,. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999; 21 (1): 70-71. (Pubitemid 29036285)
18. Kleinberg DL, Ruan W, Yee D, Kovacs KT, Vidal S,. Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice. Endocrinology 2007; 148 (3): 1080-1088.
19. Ohlson N, Bergh A, Stattin P, Wikstrom P,. Castration-induced epithelial cell death in human prostate tissue is related to locally reduced IGF-1 levels. Prostate 2007; 67 (1): 32-40. (Pubitemid 46013465)
20. Ohlson N, Bergh A, Persson ML, Wikstrom P,. Castration rapidly decreases local insulin-like growth factor-1 levels and inhibits its effects in the ventral prostate in mice. Prostate 2006; 66 (16): 1687-1697. (Pubitemid 44893895)
21. Wu Y, Zhao W, Zhao J, Pan J, Wu Q, Zhang Y, Bauman WA, Cardozo CP,. Identification of androgen response elements in the insulin-like growth factor I upstream promoter. Endocrinology 2007; 148 (6): 2984-2993. (Pubitemid 46984806)
22. Gray LE, Ostby J, Furr J, Wolf CJ, Lambright C, Parks L, Veeramachaneni DN, Wilson V, Price M, Hotchkiss A, Orlando E, Guillette L,. Effects of environmental antiandrogens on reproductive development in experimental animals. Hum Reprod Update 2001; 7 (3): 248-264. (Pubitemid 32440287)
23. Cooke PS, Young P, Cunha GR,. Androgen receptor expression in developing male reproductive organs. Endocrinology 1991; 128 (6): 2867-2873.
24. Cunha GR, Chung LW,. Stromal-epithelial interactions-I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice. J Steroid Biochem 1981; 14 (12): 1317-1324. (Pubitemid 12136929)
25. Cunha GR, Donjacour A,. Stromal-epithelial interactions in normal and abnormal prostatic development. Prog Clin Biol Res 1987; 239: 251-272.
26. Frutkin AD, Shi H, Otsuka G, Leveen P, Karlsson S, Dichek DA,. A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre. J Mol Cell Cardiol 2006; 41 (4): 724-731. (Pubitemid 44374534)
27. Umans L, Cox L, Tjwa M, Bito V, Vermeire L, Laperre K, Sipido K, Moons L, Huylebroeck D, Zwijsen A,. Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis. Am J Pathol 2007; 170 (5): 1460-1472. (Pubitemid 47339293)
28. Berry PA, Maitland NJ, Collins AT,. Androgen receptor signalling in prostate: Effects of stromal factors on normal and cancer stem cells. Mol Cell Endocrinol 2008; 288 (1-2): 30-37.
29. Ruan W, Powell-Braxton L, Kopchick JJ, Kleinberg DL,. Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development. Endocrinology 1999; 140 (5): 1984-1989. (Pubitemid 30639064)
30. Furukawa J, Wraight CJ, Freier SM, Peralta E, Atley LM, Monia BP, Gleave ME, Cox ME,. Antisense oligonucleotide targeting of insulin-like growth factor-1 receptor (IGF-1R) in prostate cancer. Prostate 2010; 70 (2): 206-218.