메뉴 건너뛰기




Volumn 369, Issue 1633, 2014, Pages

Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo

Author keywords

Alzheimer's disease; Amyloid protein; Long term potentiation; Muscarinic receptor; Nicotinic receptor; NMDA receptor

Indexed keywords

BRAIN; ENZYME ACTIVITY; INHIBITION; NEUROLOGY; PROTEIN; TIME DEPENDENT BEHAVIOR;

EID: 84888779957     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2013.0147     Document Type: Article
Times cited : (26)

References (59)
  • 1
    • 84860554747 scopus 로고    scopus 로고
    • New and emerging treatments for Alzheimer's disease
    • (doi:10.1586/ern.12.43)
    • Corbett A, Smith J, Ballard C. 2012 New and emerging treatments for Alzheimer's disease. Expert Rev. Neurother. 12, 535-543. (doi:10.1586/ern.12.43)
    • (2012) Expert Rev. Neurother. , vol.12 , pp. 535-543
    • Corbett, A.1    Smith, J.2    Ballard, C.3
  • 2
    • 79956076567 scopus 로고    scopus 로고
    • Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • (doi:10.1016/j.jalz.2011.03.004)
    • Jack Jr CR, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH. 2011 Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 7, 257-262. (doi:10.1016/j.jalz.2011.03.004)
    • (2011) Alzheimers Dement. , vol.7 , pp. 257-262
    • Jack Jr., C.R.1    Albert, M.S.2    Knopman, D.S.3    McKhann, G.M.4    Sperling, R.A.5    Carrillo, M.C.6    Thies, B.7    Phelps, C.H.8
  • 3
    • 84867328498 scopus 로고    scopus 로고
    • Pharmacological treatment of dementia
    • (doi:10.1097/YCO. 0b013e328358e4f2)
    • Schwarz S, Froelich L, Burns A. 2012 Pharmacological treatment of dementia. Curr. Opin Psychiatry 25, 542-550. (doi:10.1097/YCO. 0b013e328358e4f2)
    • (2012) Curr. Opin Psychiatry , vol.25 , pp. 542-550
    • Schwarz, S.1    Froelich, L.2    Burns, A.3
  • 5
    • 84857642949 scopus 로고    scopus 로고
    • The toxic Ab oligomer and Alzheimer's disease: An emperor in need of clothes
    • (doi:10.1038/nn.3028)
    • Benilova I, Karran E, De Strooper B. 2012 The toxic Ab oligomer and Alzheimer's disease: an emperor in need of clothes. Nat. Neurosci. 15, 349-357. (doi:10.1038/nn.3028)
    • (2012) Nat. Neurosci. , vol.15 , pp. 349-357
    • Benilova, I.1    Karran, E.2    De Strooper, B.3
  • 6
    • 84655162704 scopus 로고    scopus 로고
    • Soluble Ab oligomer production and toxicity
    • (doi:10.1111/j.1471-4159.2011.07478.x)
    • Larson ME, Lesne SE. 2012 Soluble Ab oligomer production and toxicity. J. Neurochem. 120(Suppl. 1), 125-139. (doi:10.1111/j.1471-4159.2011.07478.x)
    • (2012) J. Neurochem. , vol.120 , Issue.SUPPL. 1 , pp. 125-139
    • Larson, M.E.1    Lesne, S.E.2
  • 7
    • 84855523295 scopus 로고    scopus 로고
    • Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances
    • (doi:10.1016/j.pbb. 2011.04.013)
    • Hu NW, Ondrejcak T, Rowan MJ. 2012 Glutamate receptors in preclinical research on Alzheimer's disease: update on recent advances. Pharmacol. Biochem. Behav. 100, 855-862. (doi:10.1016/j.pbb. 2011.04.013)
    • (2012) Pharmacol. Biochem. Behav. , vol.100 , pp. 855-862
    • Hu, N.W.1    Ondrejcak, T.2    Rowan, M.J.3
  • 9
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-b-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
    • (doi:10.1038/nn.2583)
    • Palop JJ, Mucke L. 2010 Amyloid-b-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat. Neurosci. 13, 812-818. (doi:10.1038/nn.2583)
    • (2010) Nat. Neurosci. , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 10
    • 3042798841 scopus 로고    scopus 로고
    • β-amyloidmediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
    • (doi:10.1523/JNEUROSCI.0233-04.2004)
    • Wang Q, Rowan MJ, Anwyl R. 2004 β-amyloidmediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide. J. Neurosci. 24, 6049-6056. (doi:10.1523/JNEUROSCI.0233-04.2004)
    • (2004) J. Neurosci. , vol.24 , pp. 6049-6056
    • Wang, Q.1    Rowan, M.J.2    Anwyl, R.3
  • 11
    • 73949133583 scopus 로고    scopus 로고
    • GluN2B subunit-containing NMDA receptor antagonists prevent Ab-mediated synaptic plasticity disruption in vivo
    • (doi:10.1073/pnas.0908083106)
    • Hu NW, Klyubin I, Anwyl R, Rowan MJ. 2009 GluN2B subunit-containing NMDA receptor antagonists prevent Ab-mediated synaptic plasticity disruption in vivo. Proc. Natl Acad. Sci. USA 106, 20 504-20 509. (doi:10.1073/pnas.0908083106)
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 20504-20509
    • Hu, N.W.1    Klyubin, I.2    Anwyl, R.3    Rowan, M.J.4
  • 12
    • 67249087641 scopus 로고    scopus 로고
    • Soluble oligomers of amyloid b protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
    • (doi:10.1016/j.neuron.2009.05.012)
    • Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. 2009 Soluble oligomers of amyloid b protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 62, 788-801. (doi:10.1016/j.neuron.2009.05.012)
    • (2009) Neuron , vol.62 , pp. 788-801
    • Li, S.1    Hong, S.2    Shepardson, N.E.3    Walsh, D.M.4    Shankar, G.M.5    Selkoe, D.6
  • 13
    • 79952454330 scopus 로고    scopus 로고
    • Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of b-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices
    • (doi:10.1016/j.neuropharm. 2011.01.051)
    • Rammes G, Hasenjager A, Sroka-Saidi K, Deussing JM, Parsons CG. 2011 Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of b-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices. Neuropharmacology 60, 982-990. (doi:10.1016/j.neuropharm. 2011.01.051)
    • (2011) Neuropharmacology , vol.60 , pp. 982-990
    • Rammes, G.1    Hasenjager, A.2    Sroka-Saidi, K.3    Deussing, J.M.4    Parsons, C.G.5
  • 15
    • 49149124343 scopus 로고    scopus 로고
    • Amyloid-b protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
    • (doi:10.1038/nm1782)
    • Shankar GM et al. 2008 Amyloid-b protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat. Med. 14, 837-842. (doi:10.1038/nm1782)
    • (2008) Nat. Med. , vol.14 , pp. 837-842
    • Shankar, G.M.1
  • 16
    • 50849141912 scopus 로고    scopus 로고
    • Soluble amyloid-b peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo
    • (doi:10.1093/brain/awn174)
    • Hu NW, Smith IM, Walsh DM, Rowan MJ. 2008 Soluble amyloid-b peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo. Brain 131, 2414-2424. (doi:10.1093/brain/awn174)
    • (2008) Brain , vol.131 , pp. 2414-2424
    • Hu, N.W.1    Smith, I.M.2    Walsh, D.M.3    Rowan, M.J.4
  • 17
    • 77953036654 scopus 로고    scopus 로고
    • Persistent inhibition of hippocampal longterm potentiation in vivo by learned helplessness stress
    • (doi:10.1002/ hipo.20677)
    • Ryan BK, Vollmayr B, Klyubin I, Gass P, Rowan MJ. 2010 Persistent inhibition of hippocampal longterm potentiation in vivo by learned helplessness stress. Hippocampus 20, 758-767. (doi:10.1002/ hipo.20677)
    • (2010) Hippocampus , vol.20 , pp. 758-767
    • Ryan, B.K.1    Vollmayr, B.2    Klyubin, I.3    Gass, P.4    Rowan, M.J.5
  • 18
    • 0030836513 scopus 로고    scopus 로고
    • Contrasting biophysical and pharmacological properties of T-type and Rtype calcium channels
    • (doi:10.1016/S0028-3908(97)00086-5)
    • Randall AD, Tsien RW. 1997 Contrasting biophysical and pharmacological properties of T-type and Rtype calcium channels. Neuropharmacology 36, 879-893. (doi:10.1016/S0028-3908(97)00086-5)
    • (1997) Neuropharmacology , vol.36 , pp. 879-893
    • Randall, A.D.1    Tsien, R.W.2
  • 21
    • 0025089008 scopus 로고
    • Two components of long-term potentiation induced by different patterns of afferent activation
    • (doi:10.1038/347477a0)
    • Grover LM, Teyler TJ. 1990 Two components of long-term potentiation induced by different patterns of afferent activation. Nature 347, 477-479. (doi:10.1038/347477a0)
    • (1990) Nature , vol.347 , pp. 477-479
    • Grover, L.M.1    Teyler, T.J.2
  • 22
    • 77955089126 scopus 로고    scopus 로고
    • The functional neurophysiology of the amyloid precursor protein (APP) processing pathway
    • (doi:10.1016/j.neuropharm.2010.02.011)
    • Randall AD, Witton J, Booth C, Hynes-Allen A, Brown JT. 2010 The functional neurophysiology of the amyloid precursor protein (APP) processing pathway. Neuropharmacology 59, 243-267. (doi:10.1016/j.neuropharm.2010.02.011)
    • (2010) Neuropharmacology , vol.59 , pp. 243-267
    • Randall, A.D.1    Witton, J.2    Booth, C.3    Hynes-Allen, A.4    Brown, J.T.5
  • 23
    • 70350304571 scopus 로고    scopus 로고
    • Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities
    • (doi:10.1016/j.pneurobio.2009.07.009)
    • Yu JT, Chang RC, Tan L. 2009 Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities. Progr. Neurobiol. 89, 240-255. (doi:10.1016/j.pneurobio.2009.07.009)
    • (2009) Progr. Neurobiol. , vol.89 , pp. 240-255
    • Yu, J.T.1    Chang, R.C.2    Tan, L.3
  • 24
    • 77951218076 scopus 로고    scopus 로고
    • Icariin inhibits the increased inward calcium currents induced by amyloid-b(25-35) peptide in CA1 pyramidal neurons of neonatal rat hippocampal slice
    • (doi:10.1142/ S0192415X10007701)
    • Li L, Tsai HJ, Li L, Wang XM. 2010 Icariin inhibits the increased inward calcium currents induced by amyloid-b(25-35) peptide in CA1 pyramidal neurons of neonatal rat hippocampal slice. Am. J. Chinese Med. 38, 113-125. (doi:10.1142/ S0192415X10007701)
    • (2010) Am. J. Chinese Med. , vol.38 , pp. 113-125
    • Li, L.1    Tsai, H.J.2    Li, L.3    Wang, X.M.4
  • 25
    • 0035984337 scopus 로고    scopus 로고
    • Ab(25-35) and Ab(1-40) act on different calcium channels in CA1 hippocampal neurons
    • (doi:10.1016/S0006-291X(02)02072-7)
    • Rovira C, Arbez N, Mariani J. 2002 Ab(25-35) and Ab(1-40) act on different calcium channels in CA1 hippocampal neurons. Biochem. Biophys Res Commun. 296, 1317-1321. (doi:10.1016/S0006-291X(02)02072-7)
    • (2002) Biochem. Biophys Res Commun. , vol.296 , pp. 1317-1321
    • Rovira, C.1    Arbez, N.2    Mariani, J.3
  • 26
    • 27844510969 scopus 로고    scopus 로고
    • Mechanism of impairment of long-term potentiation by amyloid b is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons
    • (doi:10.1016/j.neulet.2005.08.024)
    • Nomura I, Kato N, Kita T, Takechi H. 2005 Mechanism of impairment of long-term potentiation by amyloid b is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons. Neurosci. Lett. 391, 1-6. (doi:10.1016/j.neulet.2005.08.024)
    • (2005) Neurosci. Lett. , vol.391 , pp. 1-6
    • Nomura, I.1    Kato, N.2    Kita, T.3    Takechi, H.4
  • 27
    • 64149128091 scopus 로고    scopus 로고
    • Pathway interactions and synaptic plasticity in the dendritic tuft regions of CA1 pyramidal neurons
    • (doi:10.1016/j.neuron.2009.03.007)
    • Takahashi H, Magee JC. 2009 Pathway interactions and synaptic plasticity in the dendritic tuft regions of CA1 pyramidal neurons. Neuron 62, 102-111. (doi:10.1016/j.neuron.2009.03.007)
    • (2009) Neuron , vol.62 , pp. 102-111
    • Takahashi, H.1    Magee, J.C.2
  • 28
    • 0042861385 scopus 로고    scopus 로고
    • Plasticity of calcium channels in dendritic spines
    • (doi:10.1038/nn1112)
    • Yasuda R, Sabatini BL, Svoboda K. 2003 Plasticity of calcium channels in dendritic spines. Nat. Neurosci. 6, 948-955. (doi:10.1038/nn1112)
    • (2003) Nat. Neurosci. , vol.6 , pp. 948-955
    • Yasuda, R.1    Sabatini, B.L.2    Svoboda, K.3
  • 29
    • 79960193224 scopus 로고    scopus 로고
    • Timing-dependent septal cholinergic induction of dynamic hippocampal synaptic plasticity
    • (doi:10. 1016/j.neuron.2011.04.026)
    • Gu Z, Yakel JL. 2011 Timing-dependent septal cholinergic induction of dynamic hippocampal synaptic plasticity. Neuron 71, 155-165. (doi:10. 1016/j.neuron.2011.04.026)
    • (2011) Neuron , vol.71 , pp. 155-165
    • Gu, Z.1    Yakel, J.L.2
  • 30
    • 0141523154 scopus 로고    scopus 로고
    • Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro
    • (doi:10.1113/jphysiol. 2003.045492)
    • Mann EO, Greenfield SA. 2003 Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro. J. Physiol. 551, 539-550. (doi:10.1113/jphysiol. 2003.045492)
    • (2003) J. Physiol. , vol.551 , pp. 539-550
    • Mann, E.O.1    Greenfield, S.A.2
  • 31
    • 33845676294 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus
    • (doi:10.1111/j.1460-9568.2006. 05187.x)
    • Welsby P, Rowan M, Anwyl R. 2006 Nicotinic receptor-mediated enhancement of long-term potentiation involves activation of metabotropic glutamate receptors and ryanodine-sensitive calcium stores in the dentate gyrus. Eur. J. Neurosci. 24, 3109-3118. (doi:10.1111/j.1460-9568.2006. 05187.x)
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 3109-3118
    • Welsby, P.1    Rowan, M.2    Anwyl, R.3
  • 32
    • 58149107335 scopus 로고    scopus 로고
    • Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus
    • (doi:10.1111/j.1460-9568.2008.06562.x)
    • Welsby PJ, Rowan MJ, Anwyl R. 2009 Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus. Eur. J. Neurosci. 29, 65-75. (doi:10.1111/j.1460-9568.2008.06562.x)
    • (2009) Eur. J. Neurosci. , vol.29 , pp. 65-75
    • Welsby, P.J.1    Rowan, M.J.2    Anwyl, R.3
  • 33
    • 34547165139 scopus 로고    scopus 로고
    • β-Amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP
    • (doi:10.1016/j.neuropharm.2007.05.013)
    • Welsby PJ, Rowan MJ, Anwyl R. 2007 β-Amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP. Neuropharmacology 53, 188-195. (doi:10.1016/j.neuropharm.2007.05.013)
    • (2007) Neuropharmacology , vol.53 , pp. 188-195
    • Welsby, P.J.1    Rowan, M.J.2    Anwyl, R.3
  • 34
    • 37849030372 scopus 로고    scopus 로고
    • A role for protein kinase A and protein kinase M z in muscarinic acetylcholine receptor-initiated persistent synaptic enhancement in rat hippocampus in vivo
    • (doi:10.1016/j. neuroscience.2007.10.016)
    • Hayes J, Li S, Anwyl R, Rowan MJ. 2008 A role for protein kinase A and protein kinase M z in muscarinic acetylcholine receptor-initiated persistent synaptic enhancement in rat hippocampus in vivo. Neuroscience 151, 604-612. (doi:10.1016/j. neuroscience.2007.10.016)
    • (2008) Neuroscience , vol.151 , pp. 604-612
    • Hayes, J.1    Li, S.2    Anwyl, R.3    Rowan, M.J.4
  • 35
    • 33845226397 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo
    • (doi:10.1016/j.neuroscience.2006.10.001)
    • Li S, Cullen WK, Anwyl R, Rowan MJ. 2007 Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo. Neuroscience 144, 754-761. (doi:10.1016/j.neuroscience.2006.10.001)
    • (2007) Neuroscience , vol.144 , pp. 754-761
    • Li, S.1    Cullen, W.K.2    Anwyl, R.3    Rowan, M.J.4
  • 36
  • 37
    • 0036792096 scopus 로고    scopus 로고
    • Amyloid b-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
    • (doi:10.1073/pnas.172504199)
    • Vitolo OV, Sant'Angelo A, Costanzo V, Battaglia F, Arancio O, Shelanski M. 2002 Amyloid b-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proc. Natl Acad. Sci. USA 99, 13 217-13 221. (doi:10.1073/pnas.172504199)
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13217-13221
    • Vitolo, O.V.1    Sant'Angelo, A.2    Costanzo, V.3    Battaglia, F.4    Arancio, O.5    Shelanski, M.6
  • 38
    • 84875717632 scopus 로고    scopus 로고
    • Environmental novelty activates b2-adrenergic signaling to prevent the impairment of hippocampal LTP by Ab oligomers
    • (doi:10.1016/j.neuron.2012.12.040)
    • Li S, Jin M, Zhang D, Yang T, Koeglsperger T, Fu H, Selkoe D. 2013 Environmental novelty activates b2-adrenergic signaling to prevent the impairment of hippocampal LTP by Ab oligomers. Neuron 77, 929-941. (doi:10.1016/j.neuron.2012.12.040)
    • (2013) Neuron , vol.77 , pp. 929-941
    • Li, S.1    Jin, M.2    Zhang, D.3    Yang, T.4    Koeglsperger, T.5    Fu, H.6    Selkoe, D.7
  • 39
    • 69249202594 scopus 로고    scopus 로고
    • Inhibition of LTP by b-amyloid is prevented by activation of b2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway
    • (doi:10.1016/j.neurobiolaging.2007.12.004)
    • Wang QW, Rowan MJ, Anwyl R. 2009 Inhibition of LTP by b-amyloid is prevented by activation of b2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway. Neurobiol. Aging 30, 1608-1613. (doi:10.1016/j.neurobiolaging.2007.12.004)
    • (2009) Neurobiol. Aging , vol.30 , pp. 1608-1613
    • Wang, Q.W.1    Rowan, M.J.2    Anwyl, R.3
  • 40
    • 84655164275 scopus 로고    scopus 로고
    • Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: Perspectives and challenges in treatment of Alzheimer's disease
    • (doi:10.1111/j.1471-4159. 2011.07507.x)
    • Fisher A. 2012 Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer's disease. J. Neurochem. 120(Suppl. 1), 22-33. (doi:10.1111/j.1471-4159. 2011.07507.x)
    • (2012) J. Neurochem. , vol.120 , Issue.SUPPL. 1 , pp. 22-33
    • Fisher, A.1
  • 41
    • 0030856768 scopus 로고    scopus 로고
    • β-amyloid produces a selective block of late-phase long-term potentiation in rat hippocampus in vivo
    • (doi:10.1038/sj. bjp.0701393)
    • Cullen WK, Anwyl R, Rowan MJ. 1997 β-amyloid produces a selective block of late-phase long-term potentiation in rat hippocampus in vivo. Br. J. Pharmacol. 122, 330-334. (doi:10.1038/sj. bjp.0701393)
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 330-334
    • Cullen, W.K.1    Anwyl, R.2    Rowan, M.J.3
  • 42
    • 0028173895 scopus 로고
    • A novel nicotinic agonist facilitates induction of long-term potentiation in the rat hippocampus
    • (doi:10.1016/0304-3940(94)90433-2)
    • Hunter BE, de Fiebre CM, Papke RL, Kem WR, Meyer EM. 1994 A novel nicotinic agonist facilitates induction of long-term potentiation in the rat hippocampus. Neurosci. Lett. 168, 130-134. (doi:10.1016/0304-3940(94)90433-2)
    • (1994) Neurosci. Lett. , vol.168 , pp. 130-134
    • Hunter, B.E.1    de Fiebre, C.M.2    Papke, R.L.3    Kem, W.R.4    Meyer, E.M.5
  • 43
    • 30744443800 scopus 로고    scopus 로고
    • α7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in b-amyloid infused rats
    • (doi:10.1016/j.neuropharm.2005.09.018)
    • Chen L, Yamada K, Nabeshima T, Sokabe M. 2006 α7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in b-amyloid infused rats. Neuropharmacology 50, 254-268. (doi:10.1016/j.neuropharm.2005.09.018)
    • (2006) Neuropharmacology , vol.50 , pp. 254-268
    • Chen, L.1    Yamada, K.2    Nabeshima, T.3    Sokabe, M.4
  • 44
    • 0028982464 scopus 로고
    • α-Bungarotoxinsensitive hippocampal nicotinic receptor channel has a high calcium permeability
    • (doi:10.1016/S0006-3495(95)80213-4)
    • Castro NG, Albuquerque EX. 1995 α-Bungarotoxinsensitive hippocampal nicotinic receptor channel has a high calcium permeability. Biophys. J. 68, 516-524. (doi:10.1016/S0006-3495(95)80213-4)
    • (1995) Biophys. J. , vol.68 , pp. 516-524
    • Castro, N.G.1    Albuquerque, E.X.2
  • 45
    • 20544460348 scopus 로고    scopus 로고
    • Long-lasting cognitive improvement with nicotinic receptor agonists: Mechanisms of pharmacokinetic-pharmacodynamic discordance
    • (doi:10.1016/j. tips.2005.05.007)
    • Buccafusco JJ, Letchworth SR, Bencherif M, Lippiello PM. 2005 Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance. Trends Pharmacol. Sci. 26, 352-360. (doi:10.1016/j. tips.2005.05.007)
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 352-360
    • Buccafusco, J.J.1    Letchworth, S.R.2    Bencherif, M.3    Lippiello, P.M.4
  • 46
    • 0037067717 scopus 로고    scopus 로고
    • α-Amyloid peptide activates a7 nicotinic acetylcholine receptors expressed in Xenopus oocytes
    • (doi:10.1074/jbc.M200066200)
    • Dineley KT, Bell KA, Bui D, Sweatt JD. 2002 α-Amyloid peptide activates a7 nicotinic acetylcholine receptors expressed in Xenopus oocytes. J. Biol. Chem. 277, 25 056-25 061. (doi:10.1074/jbc.M200066200)
    • (2002) J. Biol. Chem. , vol.277 , pp. 25056-25061
    • Dineley, K.T.1    Bell, K.A.2    Bui, D.3    Sweatt, J.D.4
  • 47
    • 0034006944 scopus 로고    scopus 로고
    • β-Amyloid(1-42) binds to a7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
    • (doi:10.1074/jbc. 275.8.5626)
    • Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB. 2000 β-Amyloid(1-42) binds to a7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J. Biol. Chem. 275, 5626-5632. (doi:10.1074/jbc. 275.8.5626)
    • (2000) J. Biol. Chem. , vol.275 , pp. 5626-5632
    • Wang, H.Y.1    Lee, D.H.2    D'Andrea, M.R.3    Peterson, P.A.4    Shank, R.P.5    Reitz, A.B.6
  • 48
    • 84856299171 scopus 로고    scopus 로고
    • Activation of a7 nicotinic acetylcholine receptors persistently enhances hippocampal synaptic transmission and prevents Ass-mediated inhibition of LTP in the rat hippocampus
    • (doi:10.1016/j.ejphar.2011.12.008)
    • Ondrejcak T, Wang Q, Kew JN, Virley DJ, Upton N, Anwyl R, Rowan MJ. 2012 Activation of a7 nicotinic acetylcholine receptors persistently enhances hippocampal synaptic transmission and prevents Ass-mediated inhibition of LTP in the rat hippocampus. Eur. J. Pharmacol. 677, 63-70. (doi:10.1016/j.ejphar.2011.12.008)
    • (2012) Eur. J. Pharmacol. , vol.677 , pp. 63-70
    • Ondrejcak, T.1    Wang, Q.2    Kew, J.N.3    Virley, D.J.4    Upton, N.5    Anwyl, R.6    Rowan, M.J.7
  • 49
    • 60849097262 scopus 로고    scopus 로고
    • Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Ab oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice
    • (doi:10.1523/ JNEUROSCI.2984-08.2009)
    • Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce-Levie K, Cheng IH, Yu G-Q, Mucke L. 2009 Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Ab oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice. J. Neurosci. 29, 1977-1986. (doi:10.1523/ JNEUROSCI.2984-08.2009)
    • (2009) J. Neurosci. , vol.29 , pp. 1977-1986
    • Meilandt, W.J.1    Cisse, M.2    Ho, K.3    Wu, T.4    Esposito, L.A.5    Scearce-Levie, K.6    Cheng, I.H.7    Yu, G.-Q.8    Mucke, L.9
  • 50
    • 0028361145 scopus 로고
    • LTP in hippocampal CA1 of urethane-narcotized rats requires stronger tetanization parameters
    • (doi:10.1016/0031-9384(94)90401-4)
    • Riedel G, Seidenbecher T, Reymann KG. 1994 LTP in hippocampal CA1 of urethane-narcotized rats requires stronger tetanization parameters. Physiol. Behav. 55, 1141-1146. (doi:10.1016/0031-9384(94)90401-4)
    • (1994) Physiol. Behav. , vol.55 , pp. 1141-1146
    • Riedel, G.1    Seidenbecher, T.2    Reymann, K.G.3
  • 51
    • 77951928742 scopus 로고    scopus 로고
    • The presence of sodium dodecyl sulphate-stable Ab dimers is strongly associated with Alzheimer-type dementia
    • (doi:10.1093/brain/awq065)
    • Mc Donald JM, Savva GM, Brayne C, Welzel AT, Forster G, Shankar GM, Selkoe DJ, Ince PG, Walsh DM. 2010 The presence of sodium dodecyl sulphate-stable Ab dimers is strongly associated with Alzheimer-type dementia. Brain 133, 1328-1341. (doi:10.1093/brain/awq065)
    • (2010) Brain , vol.133 , pp. 1328-1341
    • Mc Donald, J.M.1    Savva, G.M.2    Brayne, C.3    Welzel, A.T.4    Forster, G.5    Shankar, G.M.6    Selkoe, D.J.7    Ince, P.G.8    Walsh, D.M.9
  • 52
    • 79955769953 scopus 로고    scopus 로고
    • Soluble Ab oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2Bcontaining NMDA receptors
    • (doi:10.1523/JNEUROSCI.0203-11.2011)
    • Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ. 2011 Soluble Ab oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2Bcontaining NMDA receptors. J. Neurosci. 31, 6627-6638. (doi:10.1523/JNEUROSCI.0203-11.2011)
    • (2011) J. Neurosci. , vol.31 , pp. 6627-6638
    • Li, S.1    Jin, M.2    Koeglsperger, T.3    Shepardson, N.E.4    Shankar, G.M.5    Selkoe, D.J.6
  • 53
    • 79956302348 scopus 로고    scopus 로고
    • Alzheimer's disease brain-derived amyloid-b-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein
    • (doi:10.1523/JNEUROSCI.6500-10.2011)
    • Barry AE, Klyubin I, Mc Donald JM, Mably AJ, Farrell MA, Scott M, Walsh DM, Rowan MJ. 2011 Alzheimer's disease brain-derived amyloid-b-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein. J. Neurosci. 31, 7259-7263. (doi:10.1523/JNEUROSCI.6500-10.2011)
    • (2011) J. Neurosci. , vol.31 , pp. 7259-7263
    • Barry, A.E.1    Klyubin, I.2    Mc Donald, J.M.3    Mably, A.J.4    Farrell, M.A.5    Scott, M.6    Walsh, D.M.7    Rowan, M.J.8
  • 54
    • 79958249995 scopus 로고    scopus 로고
    • Interaction between prion protein and toxic Ab assemblies can be therapeutically targeted at multiple sites
    • (doi:10.1038/ncomms1341)
    • Freir DB et al. 2011 Interaction between prion protein and toxic Ab assemblies can be therapeutically targeted at multiple sites. Nat. Commun. 2, 336. (doi:10.1038/ncomms1341)
    • (2011) Nat. Commun. , vol.2 , pp. 336
    • Freir, D.B.1
  • 56
    • 0034657130 scopus 로고    scopus 로고
    • Evidence for seeding of bamyloid by intracerebral infusion of Alzheimer brain extracts in b-amyloid precursor protein-transgenic mice
    • Kane MD et al. 2000 Evidence for seeding of bamyloid by intracerebral infusion of Alzheimer brain extracts in b-amyloid precursor protein-transgenic mice. J. Neurosci. 20, 3606-3611.
    • (2000) J. Neurosci. , vol.20 , pp. 3606-3611
    • Kane, M.D.1
  • 57
    • 80054010366 scopus 로고    scopus 로고
    • Soluble Ab seeds are potent inducers of cerebral b-amyloid deposition
    • (doi:10.1523/ JNEUROSCI.3088-11.2011)
    • Langer F, Eisele YS, Fritschi SK, Staufenbiel M, Walker LC, Jucker M. 2011 Soluble Ab seeds are potent inducers of cerebral b-amyloid deposition. J. Neurosci. 31, 14 488-14 495. (doi:10.1523/ JNEUROSCI.3088-11.2011)
    • (2011) J. Neurosci. , vol.31 , pp. 14488-14495
    • Langer, F.1    Eisele, Y.S.2    Fritschi, S.K.3    Staufenbiel, M.4    Walker, L.C.5    Jucker, M.6
  • 58
    • 0030809128 scopus 로고    scopus 로고
    • Block of LTP in rat hippocampus in vivo by b-amyloid precursor protein fragments
    • (doi:10.1097/00001756-199710200-00006)
    • Cullen WK, Suh YH, Anwyl R, Rowan MJ. 1997 Block of LTP in rat hippocampus in vivo by b-amyloid precursor protein fragments. Neuroreport 8, 3213-3217. (doi:10.1097/00001756-199710200-00006)
    • (1997) Neuroreport , vol.8 , pp. 3213-3217
    • Cullen, W.K.1    Suh, Y.H.2    Anwyl, R.3    Rowan, M.J.4
  • 59
    • 2942626182 scopus 로고    scopus 로고
    • Soluble Arctic amyloid b protein inhibits hippocampal long-term potentiation in vivo
    • (doi:10.1111/j.1460-9568.2004.03389.x)
    • Klyubin I, Walsh DM, Cullen WK, Fadeeva JV, Anwyl R, Selkoe DJ, Rowan MJ. 2004 Soluble Arctic amyloid b protein inhibits hippocampal long-term potentiation in vivo. Eur. J. Neurosci. 19, 2839-2846. (doi:10.1111/j.1460-9568.2004.03389.x)
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 2839-2846
    • Klyubin, I.1    Walsh, D.M.2    Cullen, W.K.3    Fadeeva, J.V.4    Anwyl, R.5    Selkoe, D.J.6    Rowan, M.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.