Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers

Neuron

Volumn 77, Issue 5, 2013, Pages 929-941

  Li, Shaomin ^a   Jin, Ming ^a   Zhang, Dainan ^a,b   Yang, Ting ^a   Koeglsperger, Thomas ^a,c   Fu, Hongjun ^a,d   Selkoe, Dennis J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP; ISOPRENALINE; OLIGOMER; AMPA RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1;

AEROBIC EXERCISE; AGING; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; BIOACCUMULATION; COGNITIVE THERAPY; CONTROLLED STUDY; DENDRITIC SPINE; ENVIRONMENTAL ENRICHMENT; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; INTERMETHOD COMPARISON; INTRACELLULAR SIGNALING; KINESIOTHERAPY; LONG TERM EXPOSURE; LONG TERM POTENTIATION; MALE; MOUSE; NERVE CELL PLASTICITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; PROTEIN ISOLATION; SYNAPTIC INHIBITION; TREATMENT OUTCOME; ANIMAL; C57BL MOUSE; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; ELECTROPHYSIOLOGY; ENVIRONMENT; GENETICS; HIPPOCAMPUS; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; METABOLISM; PATCH CLAMP; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYNAPTOSOME; WESTERN BLOTTING;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; AMYLOID BETA-PEPTIDES; ANIMALS; BLOTTING, WESTERN; CYTOSOL; DENDRITIC SPINES; ELECTROPHYSIOLOGICAL PHENOMENA; ENVIRONMENT; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; LONG-TERM POTENTIATION; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; PATCH-CLAMP TECHNIQUES; PHYSICAL CONDITIONING, ANIMAL; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, AMPA; SIGNAL TRANSDUCTION; SYNAPTOSOMES;

MLCS; MLOWN;

EID: 84875717632     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2012.12.040     Document Type: Article

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