-
1
-
-
70549106846
-
Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses
-
Abramov E, Dolev I, Fogel H, Ciccotosto GD, Ruff E, Slutsky I. Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses. Nat Neurosci 2009;12:1567-76.
-
(2009)
Nat Neurosci
, vol.12
, pp. 1567-1576
-
-
Abramov, E.1
Dolev, I.2
Fogel, H.3
Ciccotosto, G.D.4
Ruff, E.5
Slutsky, I.6
-
3
-
-
77950229880
-
Neural mechanisms of ageing and cognitive decline
-
Bishop NA, Lu T, Yankner BA. Neural mechanisms of ageing and cognitive decline. Nature 2010;464:529-35.
-
(2010)
Nature
, vol.464
, pp. 529-535
-
-
Bishop, N.A.1
Lu, T.2
Yankner, B.A.3
-
4
-
-
78649498235
-
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice
-
Bittner T, Fuhrmann M, Burgold S, Ochs SM, Hoffmann N, Mitteregger G, et al. Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice. PLoS One 2010;5:e15477.
-
(2010)
PLoS One
, vol.5
-
-
Bittner, T.1
Fuhrmann, M.2
Burgold, S.3
Ochs, S.M.4
Hoffmann, N.5
Mitteregger, G.6
-
5
-
-
78649417803
-
Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ss production
-
Bordji K, Becerril-Ortega J, Nicole O, Buisson A. Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ss production. J Neurosci 2010;30:15927-42.
-
(2010)
J Neurosci
, vol.30
, pp. 15927-15942
-
-
Bordji, K.1
Becerril-Ortega, J.2
Nicole, O.3
Buisson, A.4
-
6
-
-
61349088541
-
Up-regulation of astrocyte metabotropic glutamate receptor 5 by amyloid-beta peptide
-
Casley CS, Lakics V, Lee HG, Broad LM, Day TA, Cluett T, et al. Up-regulation of astrocyte metabotropic glutamate receptor 5 by amyloid-beta peptide. Brain Res 2009;1260:65-75.
-
(2009)
Brain Res
, vol.1260
, pp. 65-75
-
-
Casley, C.S.1
Lakics, V.2
Lee, H.G.3
Broad, L.M.4
Day, T.A.5
Cluett, T.6
-
7
-
-
77249117920
-
Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons
-
Cerpa W, Farias GG, Godoy JA, Fuenzalida M, Bonansco C, Inestrosa NC. Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons. Mol Neurodegener 2010;5:3.
-
(2010)
Mol Neurodegener
, vol.5
, pp. 3
-
-
Cerpa, W.1
Farias, G.G.2
Godoy, J.A.3
Fuenzalida, M.4
Bonansco, C.5
Inestrosa, N.C.6
-
8
-
-
78650970378
-
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model
-
Cisse M, Halabisky B, Harris J, Devidze N, Dubal DB, Sun B, et al. Reversing EphB2 depletion rescues cognitive functions in Alzheimer model. Nature 2011;469:472.
-
(2011)
Nature
, vol.469
, pp. 472
-
-
Cisse, M.1
Halabisky, B.2
Harris, J.3
Devidze, N.4
Dubal, D.B.5
Sun, B.6
-
10
-
-
78650659370
-
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
-
D'Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S, Ferri A, et al. Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nat Neurosci 2011;14:69-76.
-
(2011)
Nat Neurosci
, vol.14
, pp. 69-76
-
-
D'Amelio, M.1
Cavallucci, V.2
Middei, S.3
Marchetti, C.4
Pacioni, S.5
Ferri, A.6
-
11
-
-
65249093004
-
A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses
-
Deshpande A, Kawai H, Metherate R, Glabe CG, Busciglio J. A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses. J Neurosci 2009;29:4004-15.
-
(2009)
J Neurosci
, vol.29
, pp. 4004-4015
-
-
Deshpande, A.1
Kawai, H.2
Metherate, R.3
Glabe, C.G.4
Busciglio, J.5
-
12
-
-
78149392229
-
Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis
-
Eisele YS, Obermuller U, Heilbronner G, Baumann F, Kaeser SA, Wolburg H, et al. Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis. Science 2010;330:980-2.
-
(2010)
Science
, vol.330
, pp. 980-982
-
-
Eisele, Y.S.1
Obermuller, U.2
Heilbronner, G.3
Baumann, F.4
Kaeser, S.A.5
Wolburg, H.6
-
13
-
-
77956586233
-
+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice
-
+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice. J Neurosci 2010;30:12128-37.
-
(2010)
J Neurosci
, vol.30
, pp. 12128-12137
-
-
Goussakov, I.1
Miller, M.B.2
Stutzmann, G.E.3
-
14
-
-
0024363934
-
Excitatory amino acids and Alzheimer's disease
-
DOI 10.1016/0197-4580(89)90143-7
-
Greenamyre JT, Young AB. Excitatory amino acids and Alzheimer's disease. Neurobiol Aging 1989;10:593-602. (Pubitemid 19245482)
-
(1989)
Neurobiology of Aging
, vol.10
, Issue.5
, pp. 593-602
-
-
Greenamyre, J.T.1
Young, A.B.2
-
15
-
-
67449084098
-
2+/calmodulin-dependent protein kinase II synaptic distribution
-
2+/calmodulin-dependent protein kinase II synaptic distribution. J Biol Chem 2009;284:10639-49.
-
(2009)
J Biol Chem
, vol.284
, pp. 10639-10649
-
-
Gu, Z.1
Liu, W.2
Yan, Z.3
-
16
-
-
77956917231
-
Synaptic versus extrasynaptic NMDA receptor signalling: Implications for neurodegenerative disorders
-
Hardingham GE, Bading H. Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 2010;11:682-96.
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 682-696
-
-
Hardingham, G.E.1
Bading, H.2
-
17
-
-
65549119787
-
Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production
-
Hoey SE, Williams RJ, Perkinton MS. Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production. J Neurosci 2009;29:4442-60.
-
(2009)
J Neurosci
, vol.29
, pp. 4442-4460
-
-
Hoey, S.E.1
Williams, R.J.2
Perkinton, M.S.3
-
18
-
-
78650251838
-
Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration
-
Hoover BR, Reed MN, Su J, Penrod RD, Kotilinek LA, Grant MK, et al. Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron 2010;68:1067-81.
-
(2010)
Neuron
, vol.68
, pp. 1067-1081
-
-
Hoover, B.R.1
Reed, M.N.2
Su, J.3
Penrod, R.D.4
Kotilinek, L.A.5
Grant, M.K.6
-
19
-
-
33845411954
-
AMPAR Removal Underlies Abeta-Induced Synaptic Depression and Dendritic Spine Loss
-
DOI 10.1016/j.neuron.2006.10.035, PII S0896627306008725
-
Hsieh H, Boehm J, Sato C, Iwatsubo T, Tomita T, Sisodia S, et al. AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 2006;52:831-43. (Pubitemid 44828454)
-
(2006)
Neuron
, vol.52
, Issue.5
, pp. 831-843
-
-
Hsieh, H.1
Boehm, J.2
Sato, C.3
Iwatsubo, T.4
Tomita, T.5
Sisodia, S.6
Malinow, R.7
-
20
-
-
73949133583
-
GluN2B subunit-containing NMDA receptor antagonists prevent Abeta-mediated synaptic plasticity disruption in vivo
-
Hu NW, Klyubin I, Anwyl R, Rowan MJ. GluN2B subunit-containing NMDA receptor antagonists prevent Abeta-mediated synaptic plasticity disruption in vivo. Proc Natl Acad Sci U S A 2009;106:20504-9.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20504-20509
-
-
Hu, N.W.1
Klyubin, I.2
Anwyl, R.3
Rowan, M.J.4
-
21
-
-
77955322042
-
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
-
Ittner LM, Ke YD, Delerue F, Bi M, Gladbach A, van Eersel J, et al. Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell 2010;142:387-97.
-
(2010)
Cell
, vol.142
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
Bi, M.4
Gladbach, A.5
Van Eersel, J.6
-
22
-
-
79955044494
-
Soluble amyloid {beta}-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration
-
Jin M, Shepardson N, Yang T, Chen G, Walsh D, Selkoe DJ. Soluble amyloid {beta}-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration. Proc Natl Acad Sci U S A 2011;108:5819-24.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 5819-5824
-
-
Jin, M.1
Shepardson, N.2
Yang, T.3
Chen, G.4
Walsh, D.5
Selkoe, D.J.6
-
23
-
-
79955484857
-
Abeta(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3beta
-
Jo J, Whitcomb DJ, Olsen KM, Kerrigan TL, Lo SC, Bru-Mercier G, et al. Abeta(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3beta. Nat Neurosci 2011;14:545-7.
-
(2011)
Nat Neurosci
, vol.14
, pp. 545-547
-
-
Jo, J.1
Whitcomb, D.J.2
Olsen, K.M.3
Kerrigan, T.L.4
Lo, S.C.5
Bru-Mercier, G.6
-
25
-
-
78149320656
-
The benefits and limitations of animal models for translational research in neurodegenerative diseases
-
Jucker M. The benefits and limitations of animal models for translational research in neurodegenerative diseases. Nat Med 2010;16:1210-4.
-
(2010)
Nat Med
, vol.16
, pp. 1210-1214
-
-
Jucker, M.1
-
26
-
-
77955617917
-
The prion protein as a receptor for amyloid-beta
-
discussion E-5
-
Kessels HW, Nguyen LN, Nabavi S, Malinow R. The prion protein as a receptor for amyloid-beta. Nature 2010;466:E3-4 discussion E-5.
-
(2010)
Nature
, vol.466
-
-
Kessels, H.W.1
Nguyen, L.N.2
Nabavi, S.3
Malinow, R.4
-
27
-
-
0035866076
-
Use-dependent effects of amyloidogenic fragments of beta-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo
-
Kim JH, Anwyl R, Suh YH, Djamgoz MB, Rowan MJ. Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo. J Neurosci 2001;21:1327-33. (Pubitemid 32128777)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.4
, pp. 1327-1333
-
-
Kim, J.-H.1
Anwyl, R.2
Suh, Y.-H.3
Djamgoz, M.B.A.4
Rowan, M.J.5
-
28
-
-
77949669251
-
Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals
-
Kim SH, Fraser PE, Westaway D, St George-Hyslop PH, Ehrlich ME, Gandy S. Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals. J Neurosci 2010;30:3870-5.
-
(2010)
J Neurosci
, vol.30
, pp. 3870-3875
-
-
Kim, S.H.1
Fraser, P.E.2
Westaway, D.3
St George-Hyslop, P.H.4
Ehrlich, M.E.5
Gandy, S.6
-
29
-
-
79953061290
-
Protection against Abeta-mediated rapid disruption of synaptic plasticity and memory by memantine
-
Klyubin I, Wang Q, Reed MN, Irving EA, Upton N, Hofmeister J, et al. Protection against Abeta-mediated rapid disruption of synaptic plasticity and memory by memantine. Neurobiol Aging 2011;32:614.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 614
-
-
Klyubin, I.1
Wang, Q.2
Reed, M.N.3
Irving, E.A.4
Upton, N.5
Hofmeister, J.6
-
30
-
-
77951653236
-
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61
-
Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, et al. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. J Neurosci 2010;30:5948-57.
-
(2010)
J Neurosci
, vol.30
, pp. 5948-5957
-
-
Kurup, P.1
Zhang, Y.2
Xu, J.3
Venkitaramani, D.V.4
Haroutunian, V.5
Greengard, P.6
-
31
-
-
77955570062
-
Glutamate receptors, neurotoxicity and neurodegeneration
-
Lau A, Tymianski M. Glutamate receptors, neurotoxicity and neurodegeneration. Pflugers Arch 2010;460:525-42.
-
(2010)
Pflugers Arch
, vol.460
, pp. 525-542
-
-
Lau, A.1
Tymianski, M.2
-
32
-
-
49249099916
-
Coordinate action of pre- And postsynaptic brain-derived neurotrophic factor is required for AMPAR trafficking and acquisition of in vitro classical conditioning
-
Li W, Keifer J. Coordinate action of pre- and postsynaptic brain-derived neurotrophic factor is required for AMPAR trafficking and acquisition of in vitro classical conditioning. Neuroscience 2008;155:686-97.
-
(2008)
Neuroscience
, vol.155
, pp. 686-697
-
-
Li, W.1
Keifer, J.2
-
33
-
-
67249087641
-
Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
-
Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 2009;62:788-801.
-
(2009)
Neuron
, vol.62
, pp. 788-801
-
-
Li, S.1
Hong, S.2
Shepardson, N.E.3
Walsh, D.M.4
Shankar, G.M.5
Selkoe, D.6
-
34
-
-
77957350879
-
Amyloid-beta decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2
-
Liu SJ, Gasperini R, Foa L, Small DH. Amyloid-beta decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2. J Alzheimers Dis 2010;21:655-66.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 655-666
-
-
Liu, S.J.1
Gasperini, R.2
Foa, L.3
Small, D.H.4
-
35
-
-
76849116197
-
Group 1 mGluR-dependent synaptic long-term depression: Mechanisms and implications for circuitry and disease
-
Luscher C, Huber KM. Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease. Neuron 2010;65:445-59.
-
(2010)
Neuron
, vol.65
, pp. 445-459
-
-
Luscher, C.1
Huber, K.M.2
-
36
-
-
77958465822
-
Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease
-
pii:e12845
-
Ma T, Hoeffer CA, Capetillo-Zarate E, Yu F, Wong H, Lin MT, et al. Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease. PLoS One 2010;5 pii:e12845.
-
(2010)
PLoS One
, pp. 5
-
-
Ma, T.1
Hoeffer, C.A.2
Capetillo-Zarate, E.3
Yu, F.4
Wong, H.5
Lin, M.T.6
-
37
-
-
77951741984
-
Learning discloses abnormal structural and functional plasticity at hippocampal synapses in the APP23 mouse model of Alzheimer's disease
-
Middei S, Roberto A, Berretta N, Panico MB, Lista S, Bernardi G, et al. Learning discloses abnormal structural and functional plasticity at hippocampal synapses in the APP23 mouse model of Alzheimer's disease. Learn Mem 2010;17:236-40.
-
(2010)
Learn Mem
, vol.17
, pp. 236-240
-
-
Middei, S.1
Roberto, A.2
Berretta, N.3
Panico, M.B.4
Lista, S.5
Bernardi, G.6
-
38
-
-
63849180498
-
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy
-
Minkeviciene R, Rheims S, Dobszay MB, Zilberter M, Hartikainen J, Fulop L, et al. Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci 2009;29:3453-62.
-
(2009)
J Neurosci
, vol.29
, pp. 3453-3462
-
-
Minkeviciene, R.1
Rheims, S.2
Dobszay, M.B.3
Zilberter, M.4
Hartikainen, J.5
Fulop, L.6
-
39
-
-
77949516412
-
Metabotropic glutamate receptors: Physiology, pharmacology, and disease
-
Niswender CM, Conn PJ. Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu Rev Pharmacol Toxicol 2010;50:295-322.
-
(2010)
Annu Rev Pharmacol Toxicol
, vol.50
, pp. 295-322
-
-
Niswender, C.M.1
Conn, P.J.2
-
40
-
-
77952499447
-
Alzheimer's disease amyloid beta-protein and synaptic function
-
Ondrejcak T, Klyubin I, Hu NW, Barry AE, Cullen WK, Rowan MJ. Alzheimer's disease amyloid beta-protein and synaptic function. Neuromolecular Med 2010;12:13-26.
-
(2010)
Neuromolecular Med
, vol.12
, pp. 13-26
-
-
Ondrejcak, T.1
Klyubin, I.2
Hu, N.W.3
Barry, A.E.4
Cullen, W.K.5
Rowan, M.J.6
-
41
-
-
78049326855
-
Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils
-
O'Nuallain B, Freir DB, Nicoll AJ, Risse E, Ferguson N, Herron CE, et al. Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils. J Neurosci 2010;30:14411-9.
-
(2010)
J Neurosci
, vol.30
, pp. 14411-14419
-
-
O'Nuallain, B.1
Freir, D.B.2
Nicoll, A.J.3
Risse, E.4
Ferguson, N.5
Herron, C.E.6
-
42
-
-
77954132249
-
Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
-
Palop JJ, Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat Neurosci 2010a;13:812-8.
-
(2010)
Nat Neurosci
, vol.13
, pp. 812-818
-
-
Palop, J.J.1
Mucke, L.2
-
43
-
-
77952484484
-
Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: Two faces of the same coin?
-
Palop JJ, Mucke L. Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin? Neuromolecular Med 2010b;12:48-55.
-
(2010)
Neuromolecular Med
, vol.12
, pp. 48-55
-
-
Palop, J.J.1
Mucke, L.2
-
44
-
-
70350061949
-
Multimodal techniques for diagnosis and prognosis of Alzheimer's disease
-
Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. Nature 2009;461:916-22.
-
(2009)
Nature
, vol.461
, pp. 916-922
-
-
Perrin, R.J.1
Fagan, A.M.2
Holtzman, D.M.3
-
45
-
-
78149488153
-
Amyloid-independent mechanisms in Alzheimer's disease pathogenesis
-
Pimplikar SW, Nixon RA, Robakis NK, Shen J, Tsai LH. Amyloid-independent mechanisms in Alzheimer's disease pathogenesis. J Neurosci 2010;30:14946-54.
-
(2010)
J Neurosci
, vol.30
, pp. 14946-14954
-
-
Pimplikar, S.W.1
Nixon, R.A.2
Robakis, N.K.3
Shen, J.4
Tsai, L.H.5
-
46
-
-
77955089126
-
The functional neurophysiology of the amyloid precursor protein (APP) processing pathway
-
Randall AD, Witton J, Booth C, Hynes-Allen A, Brown JT. The functional neurophysiology of the amyloid precursor protein (APP) processing pathway. Neuropharmacology 2010;59:243-67.
-
(2010)
Neuropharmacology
, vol.59
, pp. 243-267
-
-
Randall, A.D.1
Witton, J.2
Booth, C.3
Hynes-Allen, A.4
Brown, J.T.5
-
47
-
-
77953658771
-
Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5
-
Renner M, Lacor PN, Velasco PT, Xu J, Contractor A, Klein WL, et al. Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5. Neuron 2010;66:739-54.
-
(2010)
Neuron
, vol.66
, pp. 739-754
-
-
Renner, M.1
Lacor, P.N.2
Velasco, P.T.3
Xu, J.4
Contractor, A.5
Klein, W.L.6
-
48
-
-
78651506630
-
Amyloid-beta/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease
-
Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, Yan F, et al. Amyloid-beta/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. J Neurosci 2011;31:700-11.
-
(2011)
J Neurosci
, vol.31
, pp. 700-711
-
-
Roberson, E.D.1
Halabisky, B.2
Yoo, J.W.3
Yao, J.4
Chin, J.5
Yan, F.6
-
49
-
-
80053652289
-
Early neuronal dysfunction by amyloid beta oligomers depends on activation of NR2B-containing NMDA receptors
-
Ronicke R, Mikhaylova M, Ronicke S, Meinhardt J, Schroder UH, Fandrich M, et al. Early neuronal dysfunction by amyloid beta oligomers depends on activation of NR2B-containing NMDA receptors. Neurobiol Aging 2011;32:2219-28.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 2219-2228
-
-
Ronicke, R.1
Mikhaylova, M.2
Ronicke, S.3
Meinhardt, J.4
Schroder, U.H.5
Fandrich, M.6
-
50
-
-
77950893260
-
Inhibition of AMPA receptor trafficking at hippocampal synapses by beta-amyloid oligomers: The mitochondrial contribution
-
Rui Y, Gu J, Yu K, Hartzell HC, Zheng JQ. Inhibition of AMPA receptor trafficking at hippocampal synapses by beta-amyloid oligomers: the mitochondrial contribution. Mol Brain 2010;3:10.
-
(2010)
Mol Brain
, vol.3
, pp. 10
-
-
Rui, Y.1
Gu, J.2
Yu, K.3
Hartzell, H.C.4
Zheng, J.Q.5
-
51
-
-
2442663046
-
Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocard
-
DOI 10.1074/jbc.M313009200
-
Seeber S, Humeny A, Herkert M, Rau T, Eschenhagen T, Becker CM. Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocard. J Biol Chem 2004;279:21062-8. (Pubitemid 38656508)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.20
, pp. 21062-21068
-
-
Seeber, S.1
Humeny, A.2
Herkert, M.3
Rau, T.4
Eschenhagen, T.5
Becker, C.-M.6
-
52
-
-
79551510136
-
Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation
-
Shipton OA, Leitz JR, Dworzak J, Acton CE, Tunbridge EM, Denk F, et al. Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation. J Neurosci 2011;3:1688.
-
(2011)
J Neurosci
, vol.3
, pp. 1688
-
-
Shipton, O.A.1
Leitz, J.R.2
Dworzak, J.3
Acton, C.E.4
Tunbridge, E.M.5
Denk, F.6
-
53
-
-
68549127183
-
Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations
-
Tampellini D, Rahman N, Gallo EF, Huang Z, Dumont M, Capetillo-Zarate E, et al. Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations. J Neurosci 2009;29:9704-13.
-
(2009)
J Neurosci
, vol.29
, pp. 9704-9713
-
-
Tampellini, D.1
Rahman, N.2
Gallo, E.F.3
Huang, Z.4
Dumont, M.5
Capetillo-Zarate, E.6
-
54
-
-
77149131235
-
Fibrillar Abeta (1-42) enhances NMDA receptor sensitivity via the integrin signaling pathway
-
Uhasz GJ, Barkoczi B, Vass G, Datki Z, Hunya A, Fulop L, et al. Fibrillar Abeta (1-42) enhances NMDA receptor sensitivity via the integrin signaling pathway. J Alzheimers Dis 2010;19:1055-67.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 1055-1067
-
-
Uhasz, G.J.1
Barkoczi, B.2
Vass, G.3
Datki, Z.4
Hunya, A.5
Fulop, L.6
-
55
-
-
75549092259
-
Amyloid beta from axons and dendrites reduces local spine number and plasticity
-
Wei W, Nguyen LN, Kessels HW, Hagiwara H, Sisodia S, Malinow R. Amyloid beta from axons and dendrites reduces local spine number and plasticity. Nat Neurosci 2010;13:190-6.
-
(2010)
Nat Neurosci
, vol.13
, pp. 190-196
-
-
Wei, W.1
Nguyen, L.N.2
Kessels, H.W.3
Hagiwara, H.4
Sisodia, S.5
Malinow, R.6
-
56
-
-
77956587739
-
+) elevation,missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines
-
+) elevation,missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci 2010;30:11938-50.
-
(2010)
J Neurosci
, vol.30
, pp. 11938-11950
-
-
Zempel, H.1
Thies, E.2
Mandelkow, E.3
Mandelkow, E.M.4
-
57
-
-
77957272505
-
Neurotrophins enhance CaMKII activity and rescue amyloid-beta-induced deficits in hippocampal synaptic plasticity
-
Zeng Y, Zhao D, Xie CW. Neurotrophins enhance CaMKII activity and rescue amyloid-beta-induced deficits in hippocampal synaptic plasticity. J Alzheimers Dis 2010;21:823-31.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 823-831
-
-
Zeng, Y.1
Zhao, D.2
Xie, C.W.3
-
58
-
-
78650491806
-
Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model
-
Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, et al. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A 2010;107:19014-9.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 19014-19019
-
-
Zhang, Y.1
Kurup, P.2
Xu, J.3
Carty, N.4
Fernandez, S.M.5
Nygaard, H.B.6
-
59
-
-
77951246736
-
Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy- 5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption
-
Zhao WQ, Santini F, Breese R, Ross D, Zhang XD, Stone DJ, et al. Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5- methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption. J Biol Chem 2010;285:7619-32.
-
(2010)
J Biol Chem
, vol.285
, pp. 7619-7632
-
-
Zhao, W.Q.1
Santini, F.2
Breese, R.3
Ross, D.4
Zhang, X.D.5
Stone, D.J.6
|